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The map label for this gene is 78046051

Identifier: 78046051

GI number: 78046051

Start: 559497

End: 561095

Strand: Reverse

Name: 78046051

Synonym: XCV0495

Alternate gene names: NA

Gene position: 561095-559497 (Counterclockwise)

Preceding gene: 78046052

Following gene: 78046050

Centisome position: 10.84

GC content: 63.98

Gene sequence:

>1599_bases
ATGCAATTCCATGTCCTGGGCGCGGCAATCTGCTGCGCGCTCTCGTTTTCTGCTGCCGCGAATGCTGCCGATGTGTCGGC
AAATGCCGCTGTTTCGCGCGCGCAATCGTTATTGGGGAACAACGCGTCTGCATTGGCCAATCGCGCGCCGGCCGACGCCT
TCATCGCACGCGACAGCATCGTCGATGCCGACGGTACCGAACATGTGCGTTTCGATCGCACCTATCAGGGCCTGCCGGTG
ATCGGCGGCGACGTGGTGGTGCACTCGCGTCGCGGGGTGATGCGTGAATTGAGCCAGACCATGGACACCACGGTGCGTCC
GAGCCTGGTGCCGGGAATCGATGCGGCAACCGCGTTGCGTGTGGCCGGTTCGCACTTCGATGTGGCGCAGGATGCCGCGC
CGCGTGCGAGTCTGGCGCTGTATGCACGCCAGGGCGCGCCGCGCCTGGTGTACGAGGTAATTTACAGCGGCGTCAAACCC
GACCAGACACCGACCGAGATGCATTACATCGTCGATGCGGTGAACCAGCGCATCCTCGAATCCTGGGATACCGTGCATAC
CGCATGTAGCGGCGGCACCAGCGCCGCTGGCACAGGACGTTCGTTGTATGCGGGCAGCGTGACGGTGAACACGACGCGCT
GCAGCAGCACCAGCTACGAAATGACCGATCTCAGTCGCGGCAGCGGTGCGACCTACAACATGCGCAACAGCACCTCCGGC
AATGGCACGCTGGTCACCGATGCCGACAATGCCTGGGGCAGCGGCACCACCGGCGATACGGTCACCGCAGCGGTCGATGC
GCATTACGGCGTGGCGTTGACCTGGGACTATTACCGCACCACGCATTCGCGCACGGGCATTGCAAACGATGGCGCCGGTG
CACGGAGCCGGGTGCATTACGGTAGTCGCTACAACAACGCCTTCTGGCAGGACAGTTGTTTCTGCATGACCTTCGGCGAT
GGCGACGGCAGCACGTTCACGCCGTTGGTGTCGGTGGATGTGGCCGGTCACGAGATGACCCACGGTGTGACCAGCCGCAC
CGCCGCGCTGACCTACTCGGGCGAATCGGGCGGTTTGAATGAAGCCACGTCCGACATCATGGGCACCATGGTGGAGTACT
CCGCTGCCAACAGCGCCGAGCCGGGCAATTATCTGATTGGCGAGAAGATCATCCCCAACAACAGCACCGGCACACTGGCG
TTGCGTTACATGTTCAAGCCAAGCCTGGATGGCAAATCGCCCGATTGCTACAGCAGCAGCCTGGGCTCGCTCAATGTGCA
CTACAGGTCGGGCGTGGCCAATCACTTCTACTATCTGCTGGCCGAAGGGGCGGTGGTGCCGAGCGGGTTCGGCTCGGGCA
CCAGCTACAACCTGACCCCGACCAGTCTGGTCTGCAGCGGCTCCACGGCGCTCACCGCGATCGGCCGCGCCGCGGCCAGC
CGCATCTGGTATCGCGCACTGACGGTCTACATGACCTCGTCCACCAACTACGCGGCGGCCCGTCGGGCCACGCTGAGCGC
GGCCACCGATCTGTACGGCAGCACGTCCACGCAATACCGCGCGGTAGCGGCGGCGTGGAGCGCGGTCTCGGTGAACTGA

Upstream 100 bases:

>100_bases
GACTGTGCAAGCGTAACTGCCGGCACCCAAGGTGCCATCGGCGACCGGCTGTCGGGGGGCTGCCGGTCTTTGCATTGCAC
GTTTTCTGGAGAGAGTCGTC

Downstream 100 bases:

>100_bases
CGGTGCGTCCCTCGCCACGCCACCAAGGCGTGGCGAGGGCACATCTGCCATGGCGCCATCCGCGCGCGTATGCTTGGATC
ATTCCTGGGAGGGAACATGA

Product: Zinc metalloprotease precursor

Products: NA

Alternate protein names: Thermostable neutral proteinase [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MQFHVLGAAICCALSFSAAANAADVSANAAVSRAQSLLGNNASALANRAPADAFIARDSIVDADGTEHVRFDRTYQGLPV
IGGDVVVHSRRGVMRELSQTMDTTVRPSLVPGIDAATALRVAGSHFDVAQDAAPRASLALYARQGAPRLVYEVIYSGVKP
DQTPTEMHYIVDAVNQRILESWDTVHTACSGGTSAAGTGRSLYAGSVTVNTTRCSSTSYEMTDLSRGSGATYNMRNSTSG
NGTLVTDADNAWGSGTTGDTVTAAVDAHYGVALTWDYYRTTHSRTGIANDGAGARSRVHYGSRYNNAFWQDSCFCMTFGD
GDGSTFTPLVSVDVAGHEMTHGVTSRTAALTYSGESGGLNEATSDIMGTMVEYSAANSAEPGNYLIGEKIIPNNSTGTLA
LRYMFKPSLDGKSPDCYSSSLGSLNVHYRSGVANHFYYLLAEGAVVPSGFGSGTSYNLTPTSLVCSGSTALTAIGRAAAS
RIWYRALTVYMTSSTNYAAARRATLSAATDLYGSTSTQYRAVAAAWSAVSVN

Sequences:

>Translated_532_residues
MQFHVLGAAICCALSFSAAANAADVSANAAVSRAQSLLGNNASALANRAPADAFIARDSIVDADGTEHVRFDRTYQGLPV
IGGDVVVHSRRGVMRELSQTMDTTVRPSLVPGIDAATALRVAGSHFDVAQDAAPRASLALYARQGAPRLVYEVIYSGVKP
DQTPTEMHYIVDAVNQRILESWDTVHTACSGGTSAAGTGRSLYAGSVTVNTTRCSSTSYEMTDLSRGSGATYNMRNSTSG
NGTLVTDADNAWGSGTTGDTVTAAVDAHYGVALTWDYYRTTHSRTGIANDGAGARSRVHYGSRYNNAFWQDSCFCMTFGD
GDGSTFTPLVSVDVAGHEMTHGVTSRTAALTYSGESGGLNEATSDIMGTMVEYSAANSAEPGNYLIGEKIIPNNSTGTLA
LRYMFKPSLDGKSPDCYSSSLGSLNVHYRSGVANHFYYLLAEGAVVPSGFGSGTSYNLTPTSLVCSGSTALTAIGRAAAS
RIWYRALTVYMTSSTNYAAARRATLSAATDLYGSTSTQYRAVAAAWSAVSVN
>Mature_532_residues
MQFHVLGAAICCALSFSAAANAADVSANAAVSRAQSLLGNNASALANRAPADAFIARDSIVDADGTEHVRFDRTYQGLPV
IGGDVVVHSRRGVMRELSQTMDTTVRPSLVPGIDAATALRVAGSHFDVAQDAAPRASLALYARQGAPRLVYEVIYSGVKP
DQTPTEMHYIVDAVNQRILESWDTVHTACSGGTSAAGTGRSLYAGSVTVNTTRCSSTSYEMTDLSRGSGATYNMRNSTSG
NGTLVTDADNAWGSGTTGDTVTAAVDAHYGVALTWDYYRTTHSRTGIANDGAGARSRVHYGSRYNNAFWQDSCFCMTFGD
GDGSTFTPLVSVDVAGHEMTHGVTSRTAALTYSGESGGLNEATSDIMGTMVEYSAANSAEPGNYLIGEKIIPNNSTGTLA
LRYMFKPSLDGKSPDCYSSSLGSLNVHYRSGVANHFYYLLAEGAVVPSGFGSGTSYNLTPTSLVCSGSTALTAIGRAAAS
RIWYRALTVYMTSSTNYAAARRATLSAATDLYGSTSTQYRAVAAAWSAVSVN

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.27 [H]

Molecular weight: Translated: 55768; Mature: 55768

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFHVLGAAICCALSFSAAANAADVSANAAVSRAQSLLGNNASALANRAPADAFIARDSI
CEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHEEECCCE
VDADGTEHVRFDRTYQGLPVIGGDVVVHSRRGVMRELSQTMDTTVRPSLVPGIDAATALR
ECCCCCCCEEECCCCCCCCEECCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VAGSHFDVAQDAAPRASLALYARQGAPRLVYEVIYSGVKPDQTPTEMHYIVDAVNQRILE
CCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SWDTVHTACSGGTSAAGTGRSLYAGSVTVNTTRCSSTSYEMTDLSRGSGATYNMRNSTSG
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCEEHHCCCCCCCCEEEECCCCCC
NGTLVTDADNAWGSGTTGDTVTAAVDAHYGVALTWDYYRTTHSRTGIANDGAGARSRVHY
CCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCEEC
GSRYNNAFWQDSCFCMTFGDGDGSTFTPLVSVDVAGHEMTHGVTSRTAALTYSGESGGLN
CCCCCCCCCCCCEEEEEEECCCCCEECEEEEEEECCCHHHCCCCCCEEEEEECCCCCCCC
EATSDIMGTMVEYSAANSAEPGNYLIGEKIIPNNSTGTLALRYMFKPSLDGKSPDCYSSS
HHHHHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCEEEEEEEECCCCCCCCCCHHHCC
LGSLNVHYRSGVANHFYYLLAEGAVVPSGFGSGTSYNLTPTSLVCSGSTALTAIGRAAAS
CCCEEEEECCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
RIWYRALTVYMTSSTNYAAARRATLSAATDLYGSTSTQYRAVAAAWSAVSVN
HHHEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECC
>Mature Secondary Structure
MQFHVLGAAICCALSFSAAANAADVSANAAVSRAQSLLGNNASALANRAPADAFIARDSI
CEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHEEECCCE
VDADGTEHVRFDRTYQGLPVIGGDVVVHSRRGVMRELSQTMDTTVRPSLVPGIDAATALR
ECCCCCCCEEECCCCCCCCEECCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
VAGSHFDVAQDAAPRASLALYARQGAPRLVYEVIYSGVKPDQTPTEMHYIVDAVNQRILE
CCCCCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SWDTVHTACSGGTSAAGTGRSLYAGSVTVNTTRCSSTSYEMTDLSRGSGATYNMRNSTSG
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCEEHHCCCCCCCCEEEECCCCCC
NGTLVTDADNAWGSGTTGDTVTAAVDAHYGVALTWDYYRTTHSRTGIANDGAGARSRVHY
CCEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCEEC
GSRYNNAFWQDSCFCMTFGDGDGSTFTPLVSVDVAGHEMTHGVTSRTAALTYSGESGGLN
CCCCCCCCCCCCEEEEEEECCCCCEECEEEEEEECCCHHHCCCCCCEEEEEECCCCCCCC
EATSDIMGTMVEYSAANSAEPGNYLIGEKIIPNNSTGTLALRYMFKPSLDGKSPDCYSSS
HHHHHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCEEEEEEEECCCCCCCCCCHHHCC
LGSLNVHYRSGVANHFYYLLAEGAVVPSGFGSGTSYNLTPTSLVCSGSTALTAIGRAAAS
CCCEEEEECCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
RIWYRALTVYMTSSTNYAAARRATLSAATDLYGSTSTQYRAVAAAWSAVSVN
HHHEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7789802 [H]