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The map label for this gene is yicO [C]

Identifier: 78045874

GI number: 78045874

Start: 364725

End: 366218

Strand: Reverse

Name: yicO [C]

Synonym: XCV0318

Alternate gene names: 78045874

Gene position: 366218-364725 (Counterclockwise)

Preceding gene: 78045875

Following gene: 78045873

Centisome position: 7.07

GC content: 68.41

Gene sequence:

>1494_bases
GTGTGCAAACGCTCCTGCAGCGCAATCCGTGCCCGATGCCCGTGGCAAGCGCAGCGCAACAGGGCAAGATGGGCCGCCCG
CGTGCGTGCCCTGCCACGCACCCCGCCCCGTATCGATGAGATCTCTGCCGATGTTCGTTTGTCCTGCCGTCAACCGGCTG
TACGCCCCGAGCGCATGCTGATGCGCTGGCCCGGTTTTGCGCTTGCCGCCAACGGCAGCAGCGTGCGCACCGAACTGCTG
GCCGGTGCCACCACCTTCCTGACGATGGCGTACATCGTCTTCGTCAATCCCGACATCCTGGCCACCACCGGCATGGATCA
CGGCGCGGTGTTCGTCGCCACCTGCCTGGCCGCCGCACTCGGCTCGCTGTTGATGGGCATGCTGGCCAACTATCCCATCG
GCATGGCGCCGGGCATGGGCTTGAACGCGTTCTTCGCCTTCAGCGTGGTCGGCACATTGGGCTACAGCTGGCAGCAGACC
CTGGGGCTGGTGTTCGTTTCCGGCTGCCTCTTTCTGCTGCTCACCGTCACCGGCGCGCGGCGCTGGTTGGTGGATGGCAT
TCCGCCCACCTTGCGCAGCGCCATTGCGGCGGGCATTGGCTTGTTCCTGGCCCTGATCGGGCTGCAGAAGGCCGGACTGG
TGGTGGCGCATCCGCAGACCTTGCTGACCTTGGGCGATCTGCACCGGCCCGAGCCGCTGCTTGCGCTGGCCGGGCTGCTG
CTGATCGGCGTGCTGGAAGTGCGCCGCGTGCGGGGTGCCATGTTGCTGGGCATTCTTGCGGTGACCGGCGCGGCGCTGGC
GTTGGGGCTGGTGCGCTACCAAGGCGTCCTGGCGCTGCCGCCAAGCCTGGCGCCCACCTTGCTACAGCTGGATATCGTCG
GCGCCTTGCACGGCCATGGCGGCGGCGGTGCGCTCGCTGCGGTGCTGCATGTGGTGCTGGTGTTCGTGCTGGTGGAAATG
TTCGACGCCACCGGCACGCTGATGGGTGTGGCGCAACGCGCCGGCCTGCTGCACACGCCCGCGCAGCGCCGCCAGTTCGA
CCGCGCGCTGCTTGCCGACAGTACCGCCATCCTGGCCGGCTCGCTGCTCGGCACCTCCAGCACCACTGCCTATGTGGAAA
GCGCCGCCGGCGTGCAGGTGGGCGGGCGCACCGGCCTCACCGCGCTGGTGGTTGCCGCCTTGTTCTTGCTTGCCCTGCTG
TTCTCGCCGCTGGCCGCGATGGTGCCGGCCTACGCCACCGCACCCGCGCTGATCTACCTGGCCTCGGTGATGCTGCGCGA
ATGCACGCAGATCCAGTGGGACGATGTGGGCGACGCCTTGCCGGCCGCCATCTGCATGCTCGCCATGCCGCTGACCTATT
CCATTGCGACGGGGCTTGCGTTCGGCTTCGTCACCTATGCCGCGCTCAGGCTCGGCAGCGGCCGCTGGCGTGGTGTGCAC
CCGGCCACCTGGGCCATCGCGGGCTTGTTCGTGCTGCGCTATGCGCTGGAATGA

Upstream 100 bases:

>100_bases
AGCGCGCCATCGCCCACGGCACGTGCGCTGCCATGCGTGCAGCGGCGGCGCGGCATGCGCCGCAACGATGCGCGATGCCG
CGTGACGCTTCCGCGCACCT

Downstream 100 bases:

>100_bases
TGCGTGCCTCCACGTGTTCCAGGCGTGCTTGCCGGCGCGTACGTGGGTGGCTTCGGATCGCGCTGGTGGGCAAGCTATGG
GGCCGCCGGCCGTCGCACGC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MCKRSCSAIRARCPWQAQRNRARWAARVRALPRTPPRIDEISADVRLSCRQPAVRPERMLMRWPGFALAANGSSVRTELL
AGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAALGSLLMGMLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQT
LGLVFVSGCLFLLLTVTGARRWLVDGIPPTLRSAIAAGIGLFLALIGLQKAGLVVAHPQTLLTLGDLHRPEPLLALAGLL
LIGVLEVRRVRGAMLLGILAVTGAALALGLVRYQGVLALPPSLAPTLLQLDIVGALHGHGGGGALAAVLHVVLVFVLVEM
FDATGTLMGVAQRAGLLHTPAQRRQFDRALLADSTAILAGSLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALL
FSPLAAMVPAYATAPALIYLASVMLRECTQIQWDDVGDALPAAICMLAMPLTYSIATGLAFGFVTYAALRLGSGRWRGVH
PATWAIAGLFVLRYALE

Sequences:

>Translated_497_residues
MCKRSCSAIRARCPWQAQRNRARWAARVRALPRTPPRIDEISADVRLSCRQPAVRPERMLMRWPGFALAANGSSVRTELL
AGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAALGSLLMGMLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQT
LGLVFVSGCLFLLLTVTGARRWLVDGIPPTLRSAIAAGIGLFLALIGLQKAGLVVAHPQTLLTLGDLHRPEPLLALAGLL
LIGVLEVRRVRGAMLLGILAVTGAALALGLVRYQGVLALPPSLAPTLLQLDIVGALHGHGGGGALAAVLHVVLVFVLVEM
FDATGTLMGVAQRAGLLHTPAQRRQFDRALLADSTAILAGSLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALL
FSPLAAMVPAYATAPALIYLASVMLRECTQIQWDDVGDALPAAICMLAMPLTYSIATGLAFGFVTYAALRLGSGRWRGVH
PATWAIAGLFVLRYALE
>Mature_497_residues
MCKRSCSAIRARCPWQAQRNRARWAARVRALPRTPPRIDEISADVRLSCRQPAVRPERMLMRWPGFALAANGSSVRTELL
AGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAALGSLLMGMLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQT
LGLVFVSGCLFLLLTVTGARRWLVDGIPPTLRSAIAAGIGLFLALIGLQKAGLVVAHPQTLLTLGDLHRPEPLLALAGLL
LIGVLEVRRVRGAMLLGILAVTGAALALGLVRYQGVLALPPSLAPTLLQLDIVGALHGHGGGGALAAVLHVVLVFVLVEM
FDATGTLMGVAQRAGLLHTPAQRRQFDRALLADSTAILAGSLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALL
FSPLAAMVPAYATAPALIYLASVMLRECTQIQWDDVGDALPAAICMLAMPLTYSIATGLAFGFVTYAALRLGSGRWRGVH
PATWAIAGLFVLRYALE

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=431, Percent_Identity=44.7795823665893, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=44.988344988345, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1790499, Length=454, Percent_Identity=40.0881057268723, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI48994909, Length=462, Percent_Identity=39.1774891774892, Blast_Score=258, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 52208; Mature: 52208

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKRSCSAIRARCPWQAQRNRARWAARVRALPRTPPRIDEISADVRLSCRQPAVRPERML
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEECCCCCCCHHHHH
MRWPGFALAANGSSVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAL
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GSLLMGMLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQTLGLVFVSGCLFLLLTVTGAR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
RWLVDGIPPTLRSAIAAGIGLFLALIGLQKAGLVVAHPQTLLTLGDLHRPEPLLALAGLL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCHHHHHHHHH
LIGVLEVRRVRGAMLLGILAVTGAALALGLVRYQGVLALPPSLAPTLLQLDIVGALHGHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCC
GGGALAAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLHTPAQRRQFDRALLADSTAILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHH
SLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALIYL
HHHCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVMLRECTQIQWDDVGDALPAAICMLAMPLTYSIATGLAFGFVTYAALRLGSGRWRGVH
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PATWAIAGLFVLRYALE
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCKRSCSAIRARCPWQAQRNRARWAARVRALPRTPPRIDEISADVRLSCRQPAVRPERML
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEECCCCCCCHHHHH
MRWPGFALAANGSSVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAL
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GSLLMGMLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQTLGLVFVSGCLFLLLTVTGAR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
RWLVDGIPPTLRSAIAAGIGLFLALIGLQKAGLVVAHPQTLLTLGDLHRPEPLLALAGLL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCHHHHHHHHH
LIGVLEVRRVRGAMLLGILAVTGAALALGLVRYQGVLALPPSLAPTLLQLDIVGALHGHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCC
GGGALAAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLHTPAQRRQFDRALLADSTAILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHH
SLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALIYL
HHHCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVMLRECTQIQWDDVGDALPAAICMLAMPLTYSIATGLAFGFVTYAALRLGSGRWRGVH
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PATWAIAGLFVLRYALE
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]