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The map label for this gene is rihA [H]

Identifier: 78045872

GI number: 78045872

Start: 361780

End: 362949

Strand: Reverse

Name: rihA [H]

Synonym: XCV0316

Alternate gene names: 78045872

Gene position: 362949-361780 (Counterclockwise)

Preceding gene: 78045873

Following gene: 78045871

Centisome position: 7.01

GC content: 65.81

Gene sequence:

>1170_bases
ATGCCTCTCTCCATCGCCGTTGCAACGCCTTCAACCTTCCACGACAAGAACGCAATGAACGATCCGCACCGCCCCTCATC
CAGACGCCGCGTCATTCTCGAAGACGACATCGACGGCTTCACGCCCGCACAGCTGCTGCTGTTGCAATCGCCCGACGTGC
AGGTGCTGGGCATCAGTGCCGTCAGCGGCAATATCTGGCGCGATGAGGCGCTGGCGCATACCTGCCGCCTGCTGGAACTG
GCTGGCCATCCGCAGATTCCAGTGCTTCCCGGCCCGGTGCATCCGCTGCTCAATAGCGAGTCGGCCACCGAGCGCTGGGA
AGCGCTGTACGGCAAACTCGTCTGGAAAGGCGCATGGACCAGGCACTGGGTGGACGGCGACACCGTGCAAAGCGCGCCGC
GCTATCACGCCCACGATGTGGTGCCCGAGCTGGCGTTGGGCAATCCCAGCGTGGTGCGCCCCGCAGACGAGCCGGCCGCG
TTGTTCATGCTGCGCATGGTGCGTCAATACCCGGGCGAGGTGAGCATCATCGCAACCGGCCCGTTGACCAATCTGGCACT
GGCGCAATCGCTGGACCCGTCCTTTGCCACGTTGGCGCGCGAGCTGGTCTACATGGGCGGCAGCCTCAATCCACGGCAGC
AACGCAACAGCGTGAGTGCGCAGCAATTCGCACGCGAGTTCGTCAATTCGCCGCGACGCGAATTCAATATCCGCTGGGAC
CCGGAAGCGGCCAGCATCGTCATGCGCGCGCCGTGGCGGCAGATCACCATGGTGCCGGTCGACCCCTCCACCGCCACCGA
ACTCACCACCGAGTTGCTGGCGCGCATGAGTGCGGCCGACACCACGATTGGCCACGCACTGCGCCGCCGCGAGCCGGGCT
TTCCGATGTGGGACGAACTGGCCACGGCCGTGTGGCTGCGCCCCGACTTGGCCACCCGCACCGAAACGCTGTACGTCGAC
ACCAACACCGCCTTCGATGCCGGGTACGGCGACATCTTGTCGTGGGCACCGGGGTATCAGCCCGGGCTGGGCGAGCAGGC
GCAGACGGTGGTGCATGCGGTGGACGTGCCGGCATTCGAACAGCTGCTGGTCGACCGCCTCACCGCGCCGCAACCACCGG
CAGTGGGGTTACCACTTCCCCTTTTTCCCATCGGACCTCGGTCCCCTTGA

Upstream 100 bases:

>100_bases
TAGCACCGACAACGACATGACACACGCAGCGTAGGAGCGCGCCCGAGCACGAACGGGCTTAACCGGTAACGCACCGTCGC
GCGCAGACACGCTCCCACAA

Downstream 100 bases:

>100_bases
TGGAACAAGGCGCCCGCAGGGCGAATGAAGGTTCGATATGCAGATGACAGTGCTGCATCGGTAGAGTCGCTGGTGAGGAA
TGTGGAAACAAATGCCTGGC

Product: putative nucleoside hydrolase

Products: cytosine; ribose; uracil [C]

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MPLSIAVATPSTFHDKNAMNDPHRPSSRRRVILEDDIDGFTPAQLLLLQSPDVQVLGISAVSGNIWRDEALAHTCRLLEL
AGHPQIPVLPGPVHPLLNSESATERWEALYGKLVWKGAWTRHWVDGDTVQSAPRYHAHDVVPELALGNPSVVRPADEPAA
LFMLRMVRQYPGEVSIIATGPLTNLALAQSLDPSFATLARELVYMGGSLNPRQQRNSVSAQQFAREFVNSPRREFNIRWD
PEAASIVMRAPWRQITMVPVDPSTATELTTELLARMSAADTTIGHALRRREPGFPMWDELATAVWLRPDLATRTETLYVD
TNTAFDAGYGDILSWAPGYQPGLGEQAQTVVHAVDVPAFEQLLVDRLTAPQPPAVGLPLPLFPIGPRSP

Sequences:

>Translated_389_residues
MPLSIAVATPSTFHDKNAMNDPHRPSSRRRVILEDDIDGFTPAQLLLLQSPDVQVLGISAVSGNIWRDEALAHTCRLLEL
AGHPQIPVLPGPVHPLLNSESATERWEALYGKLVWKGAWTRHWVDGDTVQSAPRYHAHDVVPELALGNPSVVRPADEPAA
LFMLRMVRQYPGEVSIIATGPLTNLALAQSLDPSFATLARELVYMGGSLNPRQQRNSVSAQQFAREFVNSPRREFNIRWD
PEAASIVMRAPWRQITMVPVDPSTATELTTELLARMSAADTTIGHALRRREPGFPMWDELATAVWLRPDLATRTETLYVD
TNTAFDAGYGDILSWAPGYQPGLGEQAQTVVHAVDVPAFEQLLVDRLTAPQPPAVGLPLPLFPIGPRSP
>Mature_388_residues
PLSIAVATPSTFHDKNAMNDPHRPSSRRRVILEDDIDGFTPAQLLLLQSPDVQVLGISAVSGNIWRDEALAHTCRLLELA
GHPQIPVLPGPVHPLLNSESATERWEALYGKLVWKGAWTRHWVDGDTVQSAPRYHAHDVVPELALGNPSVVRPADEPAAL
FMLRMVRQYPGEVSIIATGPLTNLALAQSLDPSFATLARELVYMGGSLNPRQQRNSVSAQQFAREFVNSPRREFNIRWDP
EAASIVMRAPWRQITMVPVDPSTATELTTELLARMSAADTTIGHALRRREPGFPMWDELATAVWLRPDLATRTETLYVDT
NTAFDAGYGDILSWAPGYQPGLGEQAQTVVHAVDVPAFEQLLVDRLTAPQPPAVGLPLPLFPIGPRSP

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788486, Length=342, Percent_Identity=22.8070175438596, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786871, Length=341, Percent_Identity=26.099706744868, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786213, Length=219, Percent_Identity=31.0502283105023, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: NA

Molecular weight: Translated: 42812; Mature: 42681

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSIAVATPSTFHDKNAMNDPHRPSSRRRVILEDDIDGFTPAQLLLLQSPDVQVLGISA
CCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEEEECCCCEEEEEEEE
VSGNIWRDEALAHTCRLLELAGHPQIPVLPGPVHPLLNSESATERWEALYGKLVWKGAWT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCE
RHWVDGDTVQSAPRYHAHDVVPELALGNPSVVRPADEPAALFMLRMVRQYPGEVSIIATG
EECCCCCHHHCCCCCCHHHHCHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEECC
PLTNLALAQSLDPSFATLARELVYMGGSLNPRQQRNSVSAQQFAREFVNSPRREFNIRWD
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHHCCEEEC
PEAASIVMRAPWRQITMVPVDPSTATELTTELLARMSAADTTIGHALRRREPGFPMWDEL
CHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ATAVWLRPDLATRTETLYVDTNTAFDAGYGDILSWAPGYQPGLGEQAQTVVHAVDVPAFE
HHHHEECCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCHHH
QLLVDRLTAPQPPAVGLPLPLFPIGPRSP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLSIAVATPSTFHDKNAMNDPHRPSSRRRVILEDDIDGFTPAQLLLLQSPDVQVLGISA
CEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHEEEECCCCEEEEEEEE
VSGNIWRDEALAHTCRLLELAGHPQIPVLPGPVHPLLNSESATERWEALYGKLVWKGAWT
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCE
RHWVDGDTVQSAPRYHAHDVVPELALGNPSVVRPADEPAALFMLRMVRQYPGEVSIIATG
EECCCCCHHHCCCCCCHHHHCHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEECC
PLTNLALAQSLDPSFATLARELVYMGGSLNPRQQRNSVSAQQFAREFVNSPRREFNIRWD
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHHCCEEEC
PEAASIVMRAPWRQITMVPVDPSTATELTTELLARMSAADTTIGHALRRREPGFPMWDEL
CHHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ATAVWLRPDLATRTETLYVDTNTAFDAGYGDILSWAPGYQPGLGEQAQTVVHAVDVPAFE
HHHHEECCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCHHH
QLLVDRLTAPQPPAVGLPLPLFPIGPRSP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytidine; H2O; uridine [C]

Specific reaction: cytidine + H2O = cytosine + ribose uridine + H2O = uracil + ribose [C]

General reaction: Pyrimidine-specific nucleoside hydrolase [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA