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The map label for this gene is hemD

Identifier: 78045757

GI number: 78045757

Start: 237771

End: 238550

Strand: Reverse

Name: hemD

Synonym: XCV0201

Alternate gene names: NA

Gene position: 238550-237771 (Counterclockwise)

Preceding gene: 78045764

Following gene: 78045756

Centisome position: 4.61

GC content: 70.13

Gene sequence:

>780_bases
ATGACCGGCCTTGCCCATCCCGACGCTGCCTGGACCCTGATCTCGCTGCGCCCCAGCGGTGAACATGCGCCGTTACGGCG
GGCAGTTGCGCGGCATAGCGGACGGGTACTTGCGCTGTCGCCATGGCGCCTGCAGACCCATGACACCGCGCAGGCGCGAG
ACGCGCTGCGGCAGGCGCTGGCAGCACCGATTGCGATTTTCACCAGCCCGGCCGCGGTGCAGGCAGCGCATCGTCTGGCG
CCGCTGCAGCGCCCGGCGCCGGCGCACTGGGTCAGCGTGGGCGACGGCACTGCACGCGCATTGCACGCCTGCGGCATCGA
CAGCGTGGTGCGGCCGGCGCGCATGGACAGCGAAGGCCTGCTTGCGCTGCCGCTGCTGCAGGCACCGCTACAGGCCGTCG
GGCTGATCACTGCCCCCGGCGGGCGCGGCATGCTGGCGCCCACGTTGCAGCAGCGCGGTGCACGCATCGTGCGTGCCGAT
GTCTATCGACGCGTCCCGCTGCGCTTGCGCGCCTCGTCCATCCAGGCGTTGTCGCTTGCACTGCCGCGCAGCGTGCTGGC
GCTCAGTAGCGCCGAAGCGCTGACGCTGGTTCTGCAACAGCTGCCTGCCGAATTGGTCGCTGCGTGGCAACAGCGTCCGG
TAGTGGCATCCAGCGATCGCATGCTCGACGCCGCACATGCAGCCGGTTTCGTGCATGGCATGCGCGCAGCAGGCCCGTTG
CCGCAGCAGCTCGCCGCTGCTGCTGGGGCGGCAATCATGACACCACCACGACCTTGCTGA

Upstream 100 bases:

>100_bases
ATCGCTCTGGCTGCCGGCATTGCGCCATCGATTCGTACTGGCATCCCCGGATGCGGCGACAGTGGGCCGCAGGTGACCCA
CGCTCTCGCATAATCACCTC

Downstream 100 bases:

>100_bases
ACTGCGAACTCAAGCACAGCTTGCCGCCGTCCGGCGCTGCACGCCATGCTGTGTGCGATGACTGCGGCGCCTGCGCCGGT
CGTGACTGCCCGAGGATGTC

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase Protein

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTGLAHPDAAWTLISLRPSGEHAPLRRAVARHSGRVLALSPWRLQTHDTAQARDALRQALAAPIAIFTSPAAVQAAHRLA
PLQRPAPAHWVSVGDGTARALHACGIDSVVRPARMDSEGLLALPLLQAPLQAVGLITAPGGRGMLAPTLQQRGARIVRAD
VYRRVPLRLRASSIQALSLALPRSVLALSSAEALTLVLQQLPAELVAAWQQRPVVASSDRMLDAAHAAGFVHGMRAAGPL
PQQLAAAAGAAIMTPPRPC

Sequences:

>Translated_259_residues
MTGLAHPDAAWTLISLRPSGEHAPLRRAVARHSGRVLALSPWRLQTHDTAQARDALRQALAAPIAIFTSPAAVQAAHRLA
PLQRPAPAHWVSVGDGTARALHACGIDSVVRPARMDSEGLLALPLLQAPLQAVGLITAPGGRGMLAPTLQQRGARIVRAD
VYRRVPLRLRASSIQALSLALPRSVLALSSAEALTLVLQQLPAELVAAWQQRPVVASSDRMLDAAHAAGFVHGMRAAGPL
PQQLAAAAGAAIMTPPRPC
>Mature_258_residues
TGLAHPDAAWTLISLRPSGEHAPLRRAVARHSGRVLALSPWRLQTHDTAQARDALRQALAAPIAIFTSPAAVQAAHRLAP
LQRPAPAHWVSVGDGTARALHACGIDSVVRPARMDSEGLLALPLLQAPLQAVGLITAPGGRGMLAPTLQQRGARIVRADV
YRRVPLRLRASSIQALSLALPRSVLALSSAEALTLVLQQLPAELVAAWQQRPVVASSDRMLDAAHAAGFVHGMRAAGPLP
QQLAAAAGAAIMTPPRPC

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 27165; Mature: 27034

Theoretical pI: Translated: 12.22; Mature: 12.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLAHPDAAWTLISLRPSGEHAPLRRAVARHSGRVLALSPWRLQTHDTAQARDALRQAL
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHH
AAPIAIFTSPAAVQAAHRLAPLQRPAPAHWVSVGDGTARALHACGIDSVVRPARMDSEGL
HCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCHHHHHCCCCCCCCCC
LALPLLQAPLQAVGLITAPGGRGMLAPTLQQRGARIVRADVYRRVPLRLRASSIQALSLA
EEHHHHHHHHHHHEEEECCCCCCCCCHHHHHCCCEEEHHHHHHHCCCEEEHHHHHHHHHH
LPRSVLALSSAEALTLVLQQLPAELVAAWQQRPVVASSDRMLDAAHAAGFVHGMRAAGPL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PQQLAAAAGAAIMTPPRPC
HHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
TGLAHPDAAWTLISLRPSGEHAPLRRAVARHSGRVLALSPWRLQTHDTAQARDALRQAL
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCEECCCCHHHHHHHHHHHH
AAPIAIFTSPAAVQAAHRLAPLQRPAPAHWVSVGDGTARALHACGIDSVVRPARMDSEGL
HCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHCCHHHHHCCCCCCCCCC
LALPLLQAPLQAVGLITAPGGRGMLAPTLQQRGARIVRADVYRRVPLRLRASSIQALSLA
EEHHHHHHHHHHHEEEECCCCCCCCCHHHHHCCCEEEHHHHHHHCCCEEEHHHHHHHHHH
LPRSVLALSSAEALTLVLQQLPAELVAAWQQRPVVASSDRMLDAAHAAGFVHGMRAAGPL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PQQLAAAAGAAIMTPPRPC
HHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA