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The map label for this gene is fadL [H]

Identifier: 78045576

GI number: 78045576

Start: 21039

End: 22379

Strand: Reverse

Name: fadL [H]

Synonym: XCV0020

Alternate gene names: 78045576

Gene position: 22379-21039 (Counterclockwise)

Preceding gene: 78045580

Following gene: 78045575

Centisome position: 0.43

GC content: 67.11

Gene sequence:

>1341_bases
ATGTCTACCGCTTCCACTCTCAGCCGCGCCACCCTGTTGGCCGTCGGTATCGCTGGCGTGCTGGCCGTTGGTCAGGCGCA
CGGCGCCGCGTTCCAGCTGAAGGAAAACAGCGCCAAGGGCCTTGGCCGCGCATTCGCAGGTTCGGGCAGCGCCCCGGATG
ATGCCTCCATCATCGCCAACAACCCGGCAGGCATGCGCCAGCTGGACGGTCGCCTGTTCCAGGCCGACGTCAGCGCCATC
AGCTTCTCGGCCAAGTTCCAGCCCGACACCGCGGCCTACGCCAACGGCGCTCCGGTCTCCGGCGGCAACGGCGGCGACGC
CGGCATGATCGCGCCGGTCCCGGCGATGTACTTCCACGTGCCGTTCGGCGAGAACGACAACATGCACCTGGGCACCTCGC
TGACCGTGCCGTTCGGCTTCAAGACCGAATACGACCGCGACTGGGTCGGCCGCTACCACGGCACCAAGACCGAGCTGCAG
GCGATCGACTTCAACGTCGCGTTCTCCTATGACGTGAACCCGTACGTGTCCTTCGGTGCCTCGGTGTTCGCCGAGCGTCT
GGATATCGACCTGGCCAACGCCGTGGATTTCGGCAGCGTGCTGGCTGCGCGCCGCGTGCCGGGCTTCGCGCCGGGCAGCG
CCGATGGCTACTCGCGCATCAAGGGCGACAGCACCGAAGTGGGCTTCACCCTGGGCGGCTTGTTCAGCATCGACGAGAAC
ACCCACATCGGCTTCAGCTACCGCTCGCAGGTGGAACACAAGATCACCGACGGCACCGCCGACTTCACCGTGCCGGGCAG
TGCTGCCGCCGTGCTGGGCGTAGCCGCGCCGGGTACCTTCGTCGACACCAAGGGCCGCGCCACCGTCAAGCTGCCGGCCA
GCGCCACCGCCAGCTTCACGCATAACGTGAACGAGCAGTGGTCGATCATGGCCGACGTCACCCGCACCGCCTGGAGCAAG
TTCGACCAGGTCACCGTGGACTTCGCCTCCAACCAGCCCGATAGCGTGCTGGACTTCTCCTACCGCGACACCACCTTCGC
CTCGATCGGTGCCGACTACCGCATGAGCGACACGGTGACCCTGCGCGGCGGCCTGGCGTACGACCAGACCCCGACCACGG
CCGAACACCGCGACGTGCGCGTGCCGGACGCGAGCCGCAAGTGGGTTTCGCTGGGTATGAGCTGGCGTCCGTCGGCGCAG
ACCGAGTACAACTTCGGCTACACCCACCTGTTCACCAGCGACCCGACCAGCGACACCCGCAGCGCCACCGGCGACCGTCT
GGCCGGCAGCTACGACGTGAAGGGCGACGTGCTGGCCGCTTCGATCAACTACAAGTTCTGA

Upstream 100 bases:

>100_bases
TATGTCGGGGGGGGTCTCCGGCGCGCTCCGGGCACTGGATTGGTGCTGGACGCGGGCGCTGAACCGACCATTGCAGTCCT
TATCCGGAGAGCTACAACTT

Downstream 100 bases:

>100_bases
TCGCCGCAGCACGCGTTGCGTGACGAAAAACTCCGCTTCGGCGGGGTTTTTCTTTGGCGCCTTGCATGCTCCACCCACGA
CACGGGCAACGGGCAACAAG

Product: FadL family outer membrane protein

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSTASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIANNPAGMRQLDGRLFQADVSAI
SFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPAMYFHVPFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQ
AIDFNVAFSYDVNPYVSFGASVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDEN
THIGFSYRSQVEHKITDGTADFTVPGSAAAVLGVAAPGTFVDTKGRATVKLPASATASFTHNVNEQWSIMADVTRTAWSK
FDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRMSDTVTLRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQ
TEYNFGYTHLFTSDPTSDTRSATGDRLAGSYDVKGDVLAASINYKF

Sequences:

>Translated_446_residues
MSTASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIANNPAGMRQLDGRLFQADVSAI
SFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPAMYFHVPFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQ
AIDFNVAFSYDVNPYVSFGASVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDEN
THIGFSYRSQVEHKITDGTADFTVPGSAAAVLGVAAPGTFVDTKGRATVKLPASATASFTHNVNEQWSIMADVTRTAWSK
FDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRMSDTVTLRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQ
TEYNFGYTHLFTSDPTSDTRSATGDRLAGSYDVKGDVLAASINYKF
>Mature_445_residues
STASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIANNPAGMRQLDGRLFQADVSAIS
FSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPAMYFHVPFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQA
IDFNVAFSYDVNPYVSFGASVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDENT
HIGFSYRSQVEHKITDGTADFTVPGSAAAVLGVAAPGTFVDTKGRATVKLPASATASFTHNVNEQWSIMADVTRTAWSKF
DQVTVDFASNQPDSVLDFSYRDTTFASIGADYRMSDTVTLRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQT
EYNFGYTHLFTSDPTSDTRSATGDRLAGSYDVKGDVLAASINYKF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=417, Percent_Identity=29.2565947242206, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 47303; Mature: 47171

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIAN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCEEEEC
NPAGMRQLDGRLFQADVSAISFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPAMYFHV
CCCCHHHHCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
PFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQAIDFNVAFSYDVNPYVSFGA
CCCCCCCEEECEEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEECCCHHHHHHH
SVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDEN
HHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCHHCCCCCCEEEEEEEEEEEECCC
THIGFSYRSQVEHKITDGTADFTVPGSAAAVLGVAAPGTFVDTKGRATVKLPASATASFT
CEECEEHHHCCCEEECCCCCCEECCCCCEEEEEEECCCCEEECCCCEEEEECCCCCCCEE
HNVNEQWSIMADVTRTAWSKFDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRMSDTVT
CCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCEEEECCCCCEECCEEE
LRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQTEYNFGYTHLFTSDPTSDTR
EECCEEECCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCCCCC
SATGDRLAGSYDVKGDVLAASINYKF
CCCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
STASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIAN
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCEEEEC
NPAGMRQLDGRLFQADVSAISFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPAMYFHV
CCCCHHHHCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEE
PFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQAIDFNVAFSYDVNPYVSFGA
CCCCCCCEEECEEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEEECCCHHHHHHH
SVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDEN
HHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCHHCCCCCCEEEEEEEEEEEECCC
THIGFSYRSQVEHKITDGTADFTVPGSAAAVLGVAAPGTFVDTKGRATVKLPASATASFT
CEECEEHHHCCCEEECCCCCCEECCCCCEEEEEEECCCCEEECCCCEEEEECCCCCCCEE
HNVNEQWSIMADVTRTAWSKFDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRMSDTVT
CCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCEEEECCCCCEEEECCCCCEECCEEE
LRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQTEYNFGYTHLFTSDPTSDTR
EECCEEECCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCCCCC
SATGDRLAGSYDVKGDVLAASINYKF
CCCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]