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The map label for this gene is cat2 [H]

Identifier: 78045205

GI number: 78045205

Start: 1210352

End: 1211650

Strand: Direct

Name: cat2 [H]

Synonym: CHY_1351

Alternate gene names: 78045205

Gene position: 1210352-1211650 (Clockwise)

Preceding gene: 78044080

Following gene: 78045170

Centisome position: 50.4

GC content: 40.42

Gene sequence:

>1299_bases
ATGCCAGCAACACCTTCAGCAGAATACCAAAAAAAACTGGTAGATGTAGACCACGCCCTTTCTTTGATAAAAGATAACGA
TAATATTGTGGTTTCCCTTGGTGCAGCAGAACCATTACTTCTTTTGGAAGGTTTAGGTAAAAAAGCTTTGGAATTAAAAG
GAGTTAAAGTTTACCAAATACTGCCCGTCCATTCTCCATCTTACTTAAAACCAGAATTGAGCGATAACATAAGGCACATA
TCATTTTTCGCTGGCAAACCGGTCCGGGAGTTAATCCATCAGGGGTATGCCGAGGCAATTCCCTGTAACTTTCATGATGT
TCCCCGAATTATTCAGGATTATTTAGATGTCGATGTTTTTATGACAACGGTTTCGCCCATGGATGAACATGGTTTTTTTA
GCCTGGGAACATCGGTGGATTATTCGCTGGCCGCTCTTAAAAAAGCCAAAAAAGTAATAGTTGAAGTAAATCCGAATATG
CCAAGGACTCTGGGACAAGGAATAGTGCATATTTCCGAAATAGATTTTTTAATTGAAAGCAAGCGCGAGCTTCCTGAACT
TCCTTCGGAAGATCTCAAACCGGAAGATTACCGGATAGGTGAGTTTATTGCTGAACTGGTGGAAGATGAGTCAACTCTGC
AGTTGGGAATTGGTGCTATACCCAACGCAGTTGCGAAACTCTTATTAAACAAACGCGACTTGGGCATTCATACCGAGATG
ATTACTGACAGCATGGTCGATTTAGTAGAAGCGGGTGTGGTTACAGGACGGGCTAAAACACTTCATCCCTATAAAATAAT
TGGTACCTTTGCCTTTGGTTCCAAAAAACTTTATAAGTTTTTAAACAATAACCCAATGGTTGAAATGCACCCTGTTTCGT
ATACCAATAATCCGTGGGTGATTGGTCAAAACAAAAAAATGGTTTCCATCAATACAACAATAGAAATTGATTTATGGGGG
CAATGTGCATCCGAAAGTATAGGCACAAAAATTTACAGCGGTAGCGGCGGTCAGGCAGACTTTGCCCGTGGGGTTTTGTA
TTCTCCCGGGGGTAAAGGTATAATTGCCCTTTATTCTACAGCAAAAGACGGACAGATTTCCAAAATTGTTCCCACATTAA
AACCGGGAGCTATAGTCACCAACTCAAAAAACGATGTTGATTATGTTGTTACGGAATTTGGTGTAGCCAAACTTCGGGGA
AAGACCTACAGAGAAAGAGCTAAAGCCCTAATAAACATAGCCCATCCCGATTTCAGAGACGAACTTAAGTTTCAAGCAAA
AAAGTTAAATATATTGTAA

Upstream 100 bases:

>100_bases
TACCAGTGAAGTACAAAGAATAGTTATTTCTTCGTATATCTTAAAGGAGTTTTAATTGGTATAATAATCCTGTATAAGAC
TAAAGCAGAGGAGGAGCCTA

Downstream 100 bases:

>100_bases
TTAATTCTTTCAGGGGGGGATTTAACTTTATGAAATTAGTAGTCCTTTTAAAGCAAACCTTTGACACCGAAGCCAAGATA
GTATTAAAGGACGGGAAAAT

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MPATPSAEYQKKLVDVDHALSLIKDNDNIVVSLGAAEPLLLLEGLGKKALELKGVKVYQILPVHSPSYLKPELSDNIRHI
SFFAGKPVRELIHQGYAEAIPCNFHDVPRIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVIVEVNPNM
PRTLGQGIVHISEIDFLIESKRELPELPSEDLKPEDYRIGEFIAELVEDESTLQLGIGAIPNAVAKLLLNKRDLGIHTEM
ITDSMVDLVEAGVVTGRAKTLHPYKIIGTFAFGSKKLYKFLNNNPMVEMHPVSYTNNPWVIGQNKKMVSINTTIEIDLWG
QCASESIGTKIYSGSGGQADFARGVLYSPGGKGIIALYSTAKDGQISKIVPTLKPGAIVTNSKNDVDYVVTEFGVAKLRG
KTYRERAKALINIAHPDFRDELKFQAKKLNIL

Sequences:

>Translated_432_residues
MPATPSAEYQKKLVDVDHALSLIKDNDNIVVSLGAAEPLLLLEGLGKKALELKGVKVYQILPVHSPSYLKPELSDNIRHI
SFFAGKPVRELIHQGYAEAIPCNFHDVPRIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVIVEVNPNM
PRTLGQGIVHISEIDFLIESKRELPELPSEDLKPEDYRIGEFIAELVEDESTLQLGIGAIPNAVAKLLLNKRDLGIHTEM
ITDSMVDLVEAGVVTGRAKTLHPYKIIGTFAFGSKKLYKFLNNNPMVEMHPVSYTNNPWVIGQNKKMVSINTTIEIDLWG
QCASESIGTKIYSGSGGQADFARGVLYSPGGKGIIALYSTAKDGQISKIVPTLKPGAIVTNSKNDVDYVVTEFGVAKLRG
KTYRERAKALINIAHPDFRDELKFQAKKLNIL
>Mature_431_residues
PATPSAEYQKKLVDVDHALSLIKDNDNIVVSLGAAEPLLLLEGLGKKALELKGVKVYQILPVHSPSYLKPELSDNIRHIS
FFAGKPVRELIHQGYAEAIPCNFHDVPRIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVIVEVNPNMP
RTLGQGIVHISEIDFLIESKRELPELPSEDLKPEDYRIGEFIAELVEDESTLQLGIGAIPNAVAKLLLNKRDLGIHTEMI
TDSMVDLVEAGVVTGRAKTLHPYKIIGTFAFGSKKLYKFLNNNPMVEMHPVSYTNNPWVIGQNKKMVSINTTIEIDLWGQ
CASESIGTKIYSGSGGQADFARGVLYSPGGKGIIALYSTAKDGQISKIVPTLKPGAIVTNSKNDVDYVVTEFGVAKLRGK
TYRERAKALINIAHPDFRDELKFQAKKLNIL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=474, Percent_Identity=24.8945147679325, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563853, Length=429, Percent_Identity=41.4918414918415, Blast_Score=315, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI17538151, Length=420, Percent_Identity=39.0476190476191, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6319456, Length=418, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358615, Length=420, Percent_Identity=43.0952380952381, Blast_Score=328, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47613; Mature: 47481

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATPSAEYQKKLVDVDHALSLIKDNDNIVVSLGAAEPLLLLEGLGKKALELKGVKVYQI
CCCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHHCCCHHHEECCEEEEEE
LPVHSPSYLKPELSDNIRHISFFAGKPVRELIHQGYAEAIPCNFHDVPRIIQDYLDVDVF
EECCCCCCCCCCHHCCCEEEEEECCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCEEE
MTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVIVEVNPNMPRTLGQGIVHISEIDFLIES
EEECCCCCCCCCEEECCCCCHHHHHHHHCCEEEEEECCCCCHHHHCCEEEEHHHHHHHHH
KRELPELPSEDLKPEDYRIGEFIAELVEDESTLQLGIGAIPNAVAKLLLNKRDLGIHTEM
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHH
ITDSMVDLVEAGVVTGRAKTLHPYKIIGTFAFGSKKLYKFLNNNPMVEMHPVSYTNNPWV
HHHHHHHHHHHHHEECCCCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECCEECCCCEE
IGQNKKMVSINTTIEIDLWGQCASESIGTKIYSGSGGQADFARGVLYSPGGKGIIALYST
EECCCEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCCCHHHCCEEECCCCCEEEEEEEC
AKDGQISKIVPTLKPGAIVTNSKNDVDYVVTEFGVAKLRGKTYRERAKALINIAHPDFRD
CCCCCHHHHCCCCCCCEEEECCCCCCHHHHHHHCHHHHCCHHHHHHHHHEEEECCCCHHH
ELKFQAKKLNIL
HHHHHHHHCCCC
>Mature Secondary Structure 
PATPSAEYQKKLVDVDHALSLIKDNDNIVVSLGAAEPLLLLEGLGKKALELKGVKVYQI
CCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCCHHHHHHHCCCHHHEECCEEEEEE
LPVHSPSYLKPELSDNIRHISFFAGKPVRELIHQGYAEAIPCNFHDVPRIIQDYLDVDVF
EECCCCCCCCCCHHCCCEEEEEECCCHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCEEE
MTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVIVEVNPNMPRTLGQGIVHISEIDFLIES
EEECCCCCCCCCEEECCCCCHHHHHHHHCCEEEEEECCCCCHHHHCCEEEEHHHHHHHHH
KRELPELPSEDLKPEDYRIGEFIAELVEDESTLQLGIGAIPNAVAKLLLNKRDLGIHTEM
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCHHHH
ITDSMVDLVEAGVVTGRAKTLHPYKIIGTFAFGSKKLYKFLNNNPMVEMHPVSYTNNPWV
HHHHHHHHHHHHHEECCCCCCCCEEEEEEEECCHHHHHHHHCCCCEEEEECCEECCCCEE
IGQNKKMVSINTTIEIDLWGQCASESIGTKIYSGSGGQADFARGVLYSPGGKGIIALYST
EECCCEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCCCHHHCCEEECCCCCEEEEEEEC
AKDGQISKIVPTLKPGAIVTNSKNDVDYVVTEFGVAKLRGKTYRERAKALINIAHPDFRD
CCCCCHHHHCCCCCCCEEEECCCCCCHHHHHHHCHHHHCCHHHHHHHHHEEEECCCCHHH
ELKFQAKKLNIL
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]