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The map label for this gene is lepB [H]

Identifier: 78044888

GI number: 78044888

Start: 1218522

End: 1219076

Strand: Direct

Name: lepB [H]

Synonym: CHY_1360

Alternate gene names: 78044888

Gene position: 1218522-1219076 (Clockwise)

Preceding gene: 78043131

Following gene: 78045221

Centisome position: 50.74

GC content: 36.76

Gene sequence:

>555_bases
ATGTTCAGCGAAACTGAAAAAGAAACAACAAAAAGTTTTTCCTGGAAAAATGAAATAAAAGAATTCATTTCAGCAGCAAT
CTGGGCAGTAATTTTAGCGTTTATCATTAAAACTTTTATCTTTCAACTGACTTACGTTCCAACCGGTTCAATGATACCCA
CAATTTTACCAAACGACCGGGTCGTAGTTTTGAAATTCTGGTATAAAATTAAGCCTATAGAGCGGGGACAAATAGTGGTT
TTTGATCCTCCGAATTCAGCAAATTCACCGCCCTTTATAAAAAGAGTAATTGGGCTTCCGGGGGAAACATTGGAAATTAA
AAATAATACCGTTTACATCAACGGTAAACCGTTAAAGGAAAATTATTTACCTGCAAAAATGGAAATGGAACCCTTTGGAC
CTTTTAAAATTCCCAAAGATGCAATTTTTGTTATGGGTGATAATCGCCAACACAGTGCTGATAGCAGGTATTTTGGTGCG
GTACCGATAAAAAACATAAAAGGTCGGGCAGTTTTAACCTACTGGCCGCTTAACCGGGTAAAGGTCTTAAGATAA

Upstream 100 bases:

>100_bases
GCGGCCAATCTTTTGGGAATATCCCGCCAATGGCTTCACAAAAGACTAAAATATTTTAACCTTTTACCTTAAAAAATTTT
TGGAAAGGACGTAAAAGACA

Downstream 100 bases:

>100_bases
CCAGAAAGTCTGGTTATCTTTTTTAAAGCTTTTTAGTTTACATAATACTTATTATGGGAAGTTATTTTTTAAACAAAAAA
GTGGACTACAAAGTTAGTCC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MFSETEKETTKSFSWKNEIKEFISAAIWAVILAFIIKTFIFQLTYVPTGSMIPTILPNDRVVVLKFWYKIKPIERGQIVV
FDPPNSANSPPFIKRVIGLPGETLEIKNNTVYINGKPLKENYLPAKMEMEPFGPFKIPKDAIFVMGDNRQHSADSRYFGA
VPIKNIKGRAVLTYWPLNRVKVLR

Sequences:

>Translated_184_residues
MFSETEKETTKSFSWKNEIKEFISAAIWAVILAFIIKTFIFQLTYVPTGSMIPTILPNDRVVVLKFWYKIKPIERGQIVV
FDPPNSANSPPFIKRVIGLPGETLEIKNNTVYINGKPLKENYLPAKMEMEPFGPFKIPKDAIFVMGDNRQHSADSRYFGA
VPIKNIKGRAVLTYWPLNRVKVLR
>Mature_184_residues
MFSETEKETTKSFSWKNEIKEFISAAIWAVILAFIIKTFIFQLTYVPTGSMIPTILPNDRVVVLKFWYKIKPIERGQIVV
FDPPNSANSPPFIKRVIGLPGETLEIKNNTVYINGKPLKENYLPAKMEMEPFGPFKIPKDAIFVMGDNRQHSADSRYFGA
VPIKNIKGRAVLTYWPLNRVKVLR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323800, Length=151, Percent_Identity=32.4503311258278, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21109; Mature: 21109

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSETEKETTKSFSWKNEIKEFISAAIWAVILAFIIKTFIFQLTYVPTGSMIPTILPNDR
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCC
VVVLKFWYKIKPIERGQIVVFDPPNSANSPPFIKRVIGLPGETLEIKNNTVYINGKPLKE
EEEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCEEEECCCCCCC
NYLPAKMEMEPFGPFKIPKDAIFVMGDNRQHSADSRYFGAVPIKNIKGRAVLTYWPLNRV
CCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCEEEEEECCCEE
KVLR
EECC
>Mature Secondary Structure
MFSETEKETTKSFSWKNEIKEFISAAIWAVILAFIIKTFIFQLTYVPTGSMIPTILPNDR
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCC
VVVLKFWYKIKPIERGQIVVFDPPNSANSPPFIKRVIGLPGETLEIKNNTVYINGKPLKE
EEEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCEEEECCCCCCC
NYLPAKMEMEPFGPFKIPKDAIFVMGDNRQHSADSRYFGAVPIKNIKGRAVLTYWPLNRV
CCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCEEEEEECCCEE
KVLR
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]