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The map label for this gene is lldD [H]

Identifier: 78044740

GI number: 78044740

Start: 1175367

End: 1176389

Strand: Direct

Name: lldD [H]

Synonym: CHY_1319

Alternate gene names: 78044740

Gene position: 1175367-1176389 (Clockwise)

Preceding gene: 78043934

Following gene: 78043161

Centisome position: 48.94

GC content: 47.51

Gene sequence:

>1023_bases
ATGGACTTAAAAGAAATTAGGGCAACCGCCAGAGAAAAGCTCAAGGGATTTTGCCGGGTTTGCCCGGTATGTGACGGTCG
GGCATGTGCCGGAGAAGTACCGGGAATGGGAGGAGTAGGTACCGGAAAAGCTTTTCAGGAAAATTTACGGGCTCTTTCCC
GGTATAAGTTAAATTTAAGAACGATTCACGGAGTAAAAGAACCGGATTTAAGCTTTGAACTTTTTGGGGTTAAGGTAAGC
ATGCCGGTTTTTGCTGCTCCGATTACCGGAACCACTTACAACATGGGCGGAGCGTTAACTGATGAGGAATATAGTTTAGC
GGTTGTTGAAGGTAGCCTTTTAGCTGGAACCTTAGCTTTTACCGGAGATGGAGCCGATCCCACCATGTACGGTTCGGGGT
TAAAAGCGATTAAAAAAGTGGAGGGTAAAGGTATTCCCATTATTAAACCAAGAGCGCAAGAGGAGATAATTAAAAGGATT
AGAGAAGCGGAAGAAACGGGAGCTATTGCTGTAGGGGTGGATATTGATGGAGCCGGATTACTAACGATGGCTTTAAAGGG
GCAGCCGGTCAGTCCGAAAACCCTGGAAGAAGTAATGGAAATTGTTAATTCCACCAGGCTTCCGTTTATTTTAAAAGGTA
TTATGACCCCTGATGAGGCCGAATTAGCGGTTCAGGCCGGGGCGAAAGCCATTGTGGTTTCCAACCATGGTGGAAGGACG
TTGGATGAAACTCCCGGGGCTGCCGATGTCCTGCCGGAAATTGCTGCCAGAGTAAAAGGGAAAATCACCATCCTGGCCGA
TGGAGGAGTAAGATCCGGTGTCGATGTTTTAAAACTTTTGGCGCTGGGAGCGGATGGAGTATTAATAGGGCGGCCGATAA
TTGTGGCAGCTTTTGGCGGTGGTGCCGAAGGAGTTAAAATTTACCTAGAGAAAATTAAAAAGGAACTAAGGGAAGCGATG
CTTTTAACCGGAGTTGCGCGGGTGACCGAAGTCCCGGGAACAATTATCCGGAAGGAGCAGTAA

Upstream 100 bases:

>100_bases
AACGTCGAAAGATATCTCGAAATGGGAAAAGTTTTAAAGTTACAAAAATAAAAAGGCAAACAAAAATTCTCTAAAAAAAA
TAATGAGAGGGAAAGAAATT

Downstream 100 bases:

>100_bases
GATGGGAAATTATGTTGTGGGGTTTCATCTTAATATAAAAATAACCTAGAAAAAATAAATTGAATGTAATTATTCCAACT
CAGGAGGTTTAAACATGACA

Product: FMN-dependent family dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLSFELFGVKVS
MPVFAAPITGTTYNMGGALTDEEYSLAVVEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVQAGAKAIVVSNHGGRT
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ

Sequences:

>Translated_340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLSFELFGVKVS
MPVFAAPITGTTYNMGGALTDEEYSLAVVEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVQAGAKAIVVSNHGGRT
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ
>Mature_340_residues
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLRTIHGVKEPDLSFELFGVKVS
MPVFAAPITGTTYNMGGALTDEEYSLAVVEGSLLAGTLAFTGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRI
REAEETGAIAVGVDIDGAGLLTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVQAGAKAIVVSNHGGRT
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGGGAEGVKIYLEKIKKELREAM
LLTGVARVTEVPGTIIRKEQ

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=347, Percent_Identity=33.1412103746398, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI54234014, Length=329, Percent_Identity=30.6990881458967, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI7705393, Length=329, Percent_Identity=30.6990881458967, Blast_Score=130, Evalue=1e-30,
Organism=Escherichia coli, GI1790033, Length=142, Percent_Identity=46.4788732394366, Blast_Score=121, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI193208036, Length=131, Percent_Identity=42.7480916030534, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323587, Length=143, Percent_Identity=37.0629370629371, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363140, Length=147, Percent_Identity=32.6530612244898, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78707190, Length=147, Percent_Identity=32.6530612244898, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78707188, Length=146, Percent_Identity=32.8767123287671, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 35671; Mature: 35671

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEE
TIHGVKEPDLSFELFGVKVSMPVFAAPITGTTYNMGGALTDEEYSLAVVEGSLLAGTLAF
EECCCCCCCCCEEEEEEEEECCEEECCCCCCEECCCCCCCCCCEEEEEEECCEEEEEEEE
TGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRIREAEETGAIAVGVDIDGAGL
ECCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVQAGAKAIVVSNHGGRT
EEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCC
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGG
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECC
GAEGVKIYLEKIKKELREAMLLTGVARVTEVPGTIIRKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MDLKEIRATAREKLKGFCRVCPVCDGRACAGEVPGMGGVGTGKAFQENLRALSRYKLNLR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEE
TIHGVKEPDLSFELFGVKVSMPVFAAPITGTTYNMGGALTDEEYSLAVVEGSLLAGTLAF
EECCCCCCCCCEEEEEEEEECCEEECCCCCCEECCCCCCCCCCEEEEEEECCEEEEEEEE
TGDGADPTMYGSGLKAIKKVEGKGIPIIKPRAQEEIIKRIREAEETGAIAVGVDIDGAGL
ECCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCE
LTMALKGQPVSPKTLEEVMEIVNSTRLPFILKGIMTPDEAELAVQAGAKAIVVSNHGGRT
EEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHCCCEEEEEECCCCCC
LDETPGAADVLPEIAARVKGKITILADGGVRSGVDVLKLLALGADGVLIGRPIIVAAFGG
CCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCEEEEEECC
GAEGVKIYLEKIKKELREAMLLTGVARVTEVPGTIIRKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA