| Definition | Carboxydothermus hydrogenoformans Z-2901 chromosome, complete genome. |
|---|---|
| Accession | NC_007503 |
| Length | 2,401,520 |
Click here to switch to the map view.
The map label for this gene is comEC [H]
Identifier: 78044560
GI number: 78044560
Start: 344456
End: 346633
Strand: Direct
Name: comEC [H]
Synonym: CHY_0403
Alternate gene names: 78044560
Gene position: 344456-346633 (Clockwise)
Preceding gene: 78044921
Following gene: 78043916
Centisome position: 14.34
GC content: 39.21
Gene sequence:
>2178_bases ATGGAAATTTATCTTGCTTTCATTTTTTACATACTGGGAATTATCATAGCCGATCAGGGTTTTATCCCTTTTCGGCTATT TCTGTATTTGGCCTTATTGTTTATGCTTTTATATCTTGTTTTACCCCGGGAACGCAAAAGCTTAGCCGTTCTTTTAGTAG CTTTTATGCTTCTTGGAGGGGTAAACCTAAATCTTCATGTGAGTCCGGGTTTTCGGGAAGGGGAATATCGGGGAATTTGC CGGGTGGTGGAAGGGTCTACCGTAAAAAATGATAAAAACAGTTTTAAAGTAGTGGATTTAAAAACCAAAGAAACCTATTT AGTCCGGGAAAAAGAAATGGTTTTAAGGCTTCCGGGAGATATTTTAAAAATTACCGGAAGTTTCCTAAAACCAGTTCCTC CGCAAAATCCCGGCGAGTTTAACTATCCAAGTTATTTAAGACGGCAAGGAATTTATGGGGTTTTAAACGTTCAAACCGCG GAAAAAATCGGGGATAACTTTTCTTTTCTTCGGCCTTTTGCAGCAGTAAAAAATTTTCTTAAAGAAAAGTTAAATACCTA TTCTCCCGAAACTGCGGCGTTATTAAAAGGTTTGTATTTAGGGGACGATGAGGAAATTTCCCCGGAGGTTTACGATAGTT TTGCGAAAACCGGGGTCGTGCATATTTTAAGTGTCAGCGGCCTGCATTTGGGGTTGGTGGCGGGGGCAATTTATTTTTTG GGAAAGGGGTTACGGCTTTCCCGGCAATGGCAAAACCTTTTTACAATAATTTTTTGCTTTTTTTATACCGCCCTAACCGG TTTTAACCCGGCAACGGTGCGGGCCTTCTTAATGCTGGTGTTTTTGGTCGGGGCTTTTTTCTTGGGGCGGGATTATCAGC CGGTTTATCACTTATTTTTAAGTGCCTTTTTTTATCTTTTAATAAAACCTCAGGAGCTTTTTTCGGCGGGTTTTCTCTTA TCGTATTTAGCAACCCTGGGGATATTTTTAATAGGTTTACCTTTAGCGGAAAAATTAAAGTTGTATTTACCTTCTTATTT GGCCGACACTATTGGAGTTACGGTTGGTGCGCAAATTTTAACCGAGCCAATTGTATTTTATCATTATTCCCTCTTTGCTA CCCTTTCAATTATAGCCAATCTTTTAGTAGTTCCCCTTACCGGTATTATTATGGCTTCCGGAATTTTCGGTTTATTTTTA TCTCCCTTAAGACACCTAACTGAACTACTAACGGTGTTTACTTTAAATATGAACAGTCAAATGGCTTTAATTCCCGGGGC GACAATAGCAGTAAAAAAGCCTTTTTTTACATTAATTTTTCTTTTTTATTGCTGGTTATTTTTAGGATATTTTTGGTTGG TAAAAAAAGAAAAGATCGATATTGTTAAATTCTGTGTAATTGCCTTTTTAATTTTAGGAATATTTTTAGTACCAAAAGAG CACGGAAAAACTGTTTTTCTTGCCGTGGGCCAGGGGGATGCAGCGGTAATTCATACTTTGCGCGGACGCACGATTGTGGT GGATACCGGACCAAAAAACGAAAATTATGATGCGGGAAGAAAAGTTTTAGCGTATCTTCGCCAAAGTGGCACGGGGGTTA TAGACCTTTTAGTGTTGACCCATCCCCATAATGACCATTACGGGGGTGCAGAAACGCTTATCCAGAGTGCCACGGTAAAG GCGGTCTTAATTTCTCCATATTTAGGGGAAGACCAGGAATACCTGGAACTTTTAAATTTACTCCGGTTAAGAAAAATAAA AATTTATTATGCTAAAACTTCTGCCGTTATTAGTTTGGATGATGTTTCTTTACGGATATTAGGACCGGAAAGAATCTATT CCGGTACCCGCTCAGACCCCAATAACAACAGTGTAGTGCTAGCGGGTAAAATAGGCCGGAAAACCTACTTTTTTGGGGCG GACATCGAGAGAGAAGCGGAAGAAGATCTGGAAAACCAACTTCTGGCTTATTATGAAGTGGTAAAAATTCCCCATCATGG TAGTAACTTTTTTTCAGAAAGCTTTATGGAAAAGTTAAAATTTGGTTATGGAGTTATTTCCGTTGGTCAAAATAATCTTT ATGGTTTTCCCGGGGATAAGCTTTTAGCGGCTCTAAAAGGTAAGGGAAAGCTTTGGCGTACCGACCTTGAGGGGGCTTTA GTTGTCGAAAATTATTAA
Upstream 100 bases:
>100_bases GGCCCTTTGCGACTATTGAGGATCTAAAAAAAGTTAAGGGTATAGGGGACAAAAAGTTTGAAACGCTAAAAGATTATATT ACGGTTAATTAGAGGGGAAT
Downstream 100 bases:
>100_bases GTTGTATTAAAATTAAAGAAAAAAGTACCGGGGTGGAAGGATGATTGATTTAACACCTCTTTTGACTTATTATTATCTTG CTTTACTAACCCAGATGATA
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 725; Mature: 725
Protein sequence:
>725_residues MEIYLAFIFYILGIIIADQGFIPFRLFLYLALLFMLLYLVLPRERKSLAVLLVAFMLLGGVNLNLHVSPGFREGEYRGIC RVVEGSTVKNDKNSFKVVDLKTKETYLVREKEMVLRLPGDILKITGSFLKPVPPQNPGEFNYPSYLRRQGIYGVLNVQTA EKIGDNFSFLRPFAAVKNFLKEKLNTYSPETAALLKGLYLGDDEEISPEVYDSFAKTGVVHILSVSGLHLGLVAGAIYFL GKGLRLSRQWQNLFTIIFCFFYTALTGFNPATVRAFLMLVFLVGAFFLGRDYQPVYHLFLSAFFYLLIKPQELFSAGFLL SYLATLGIFLIGLPLAEKLKLYLPSYLADTIGVTVGAQILTEPIVFYHYSLFATLSIIANLLVVPLTGIIMASGIFGLFL SPLRHLTELLTVFTLNMNSQMALIPGATIAVKKPFFTLIFLFYCWLFLGYFWLVKKEKIDIVKFCVIAFLILGIFLVPKE HGKTVFLAVGQGDAAVIHTLRGRTIVVDTGPKNENYDAGRKVLAYLRQSGTGVIDLLVLTHPHNDHYGGAETLIQSATVK AVLISPYLGEDQEYLELLNLLRLRKIKIYYAKTSAVISLDDVSLRILGPERIYSGTRSDPNNNSVVLAGKIGRKTYFFGA DIEREAEEDLENQLLAYYEVVKIPHHGSNFFSESFMEKLKFGYGVISVGQNNLYGFPGDKLLAALKGKGKLWRTDLEGAL VVENY
Sequences:
>Translated_725_residues MEIYLAFIFYILGIIIADQGFIPFRLFLYLALLFMLLYLVLPRERKSLAVLLVAFMLLGGVNLNLHVSPGFREGEYRGIC RVVEGSTVKNDKNSFKVVDLKTKETYLVREKEMVLRLPGDILKITGSFLKPVPPQNPGEFNYPSYLRRQGIYGVLNVQTA EKIGDNFSFLRPFAAVKNFLKEKLNTYSPETAALLKGLYLGDDEEISPEVYDSFAKTGVVHILSVSGLHLGLVAGAIYFL GKGLRLSRQWQNLFTIIFCFFYTALTGFNPATVRAFLMLVFLVGAFFLGRDYQPVYHLFLSAFFYLLIKPQELFSAGFLL SYLATLGIFLIGLPLAEKLKLYLPSYLADTIGVTVGAQILTEPIVFYHYSLFATLSIIANLLVVPLTGIIMASGIFGLFL SPLRHLTELLTVFTLNMNSQMALIPGATIAVKKPFFTLIFLFYCWLFLGYFWLVKKEKIDIVKFCVIAFLILGIFLVPKE HGKTVFLAVGQGDAAVIHTLRGRTIVVDTGPKNENYDAGRKVLAYLRQSGTGVIDLLVLTHPHNDHYGGAETLIQSATVK AVLISPYLGEDQEYLELLNLLRLRKIKIYYAKTSAVISLDDVSLRILGPERIYSGTRSDPNNNSVVLAGKIGRKTYFFGA DIEREAEEDLENQLLAYYEVVKIPHHGSNFFSESFMEKLKFGYGVISVGQNNLYGFPGDKLLAALKGKGKLWRTDLEGAL VVENY >Mature_725_residues MEIYLAFIFYILGIIIADQGFIPFRLFLYLALLFMLLYLVLPRERKSLAVLLVAFMLLGGVNLNLHVSPGFREGEYRGIC RVVEGSTVKNDKNSFKVVDLKTKETYLVREKEMVLRLPGDILKITGSFLKPVPPQNPGEFNYPSYLRRQGIYGVLNVQTA EKIGDNFSFLRPFAAVKNFLKEKLNTYSPETAALLKGLYLGDDEEISPEVYDSFAKTGVVHILSVSGLHLGLVAGAIYFL GKGLRLSRQWQNLFTIIFCFFYTALTGFNPATVRAFLMLVFLVGAFFLGRDYQPVYHLFLSAFFYLLIKPQELFSAGFLL SYLATLGIFLIGLPLAEKLKLYLPSYLADTIGVTVGAQILTEPIVFYHYSLFATLSIIANLLVVPLTGIIMASGIFGLFL SPLRHLTELLTVFTLNMNSQMALIPGATIAVKKPFFTLIFLFYCWLFLGYFWLVKKEKIDIVKFCVIAFLILGIFLVPKE HGKTVFLAVGQGDAAVIHTLRGRTIVVDTGPKNENYDAGRKVLAYLRQSGTGVIDLLVLTHPHNDHYGGAETLIQSATVK AVLISPYLGEDQEYLELLNLLRLRKIKIYYAKTSAVISLDDVSLRILGPERIYSGTRSDPNNNSVVLAGKIGRKTYFFGA DIEREAEEDLENQLLAYYEVVKIPHHGSNFFSESFMEKLKFGYGVISVGQNNLYGFPGDKLLAALKGKGKLWRTDLEGAL VVENY
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG0658
COG function: function code R; Predicted membrane metal-binding protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=567, Percent_Identity=24.1622574955908, Blast_Score=94, Evalue=4e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 81259; Mature: 81259
Theoretical pI: Translated: 9.17; Mature: 9.17
Prosite motif: PS00327 BACTERIAL_OPSIN_RET
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEIYLAFIFYILGIIIADQGFIPFRLFLYLALLFMLLYLVLPRERKSLAVLLVAFMLLGG CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC VNLNLHVSPGFREGEYRGICRVVEGSTVKNDKNSFKVVDLKTKETYLVREKEMVLRLPGD CCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEHHHHHEECCCH ILKITGSFLKPVPPQNPGEFNYPSYLRRQGIYGVLNVQTAEKIGDNFSFLRPFAAVKNFL HHHHCHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHH KEKLNTYSPETAALLKGLYLGDDEEISPEVYDSFAKTGVVHILSVSGLHLGLVAGAIYFL HHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH GKGLRLSRQWQNLFTIIFCFFYTALTGFNPATVRAFLMLVFLVGAFFLGRDYQPVYHLFL CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH SAFFYLLIKPQELFSAGFLLSYLATLGIFLIGLPLAEKLKLYLPSYLADTIGVTVGAQIL HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH TEPIVFYHYSLFATLSIIANLLVVPLTGIIMASGIFGLFLSPLRHLTELLTVFTLNMNSQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC MALIPGATIAVKKPFFTLIFLFYCWLFLGYFWLVKKEKIDIVKFCVIAFLILGIFLVPKE EEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC HGKTVFLAVGQGDAAVIHTLRGRTIVVDTGPKNENYDAGRKVLAYLRQSGTGVIDLLVLT CCCEEEEEECCCCCEEHEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE HPHNDHYGGAETLIQSATVKAVLISPYLGEDQEYLELLNLLRLRKIKIYYAKTSAVISLD CCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCEEEEEC DVSLRILGPERIYSGTRSDPNNNSVVLAGKIGRKTYFFGADIEREAEEDLENQLLAYYEV CCEEEEECHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH VKIPHHGSNFFSESFMEKLKFGYGVISVGQNNLYGFPGDKLLAALKGKGKLWRTDLEGAL HCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCEE VVENY EEECC >Mature Secondary Structure MEIYLAFIFYILGIIIADQGFIPFRLFLYLALLFMLLYLVLPRERKSLAVLLVAFMLLGG CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC VNLNLHVSPGFREGEYRGICRVVEGSTVKNDKNSFKVVDLKTKETYLVREKEMVLRLPGD CCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEHHHHHEECCCH ILKITGSFLKPVPPQNPGEFNYPSYLRRQGIYGVLNVQTAEKIGDNFSFLRPFAAVKNFL HHHHCHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHH KEKLNTYSPETAALLKGLYLGDDEEISPEVYDSFAKTGVVHILSVSGLHLGLVAGAIYFL HHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH GKGLRLSRQWQNLFTIIFCFFYTALTGFNPATVRAFLMLVFLVGAFFLGRDYQPVYHLFL CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH SAFFYLLIKPQELFSAGFLLSYLATLGIFLIGLPLAEKLKLYLPSYLADTIGVTVGAQIL HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH TEPIVFYHYSLFATLSIIANLLVVPLTGIIMASGIFGLFLSPLRHLTELLTVFTLNMNSQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC MALIPGATIAVKKPFFTLIFLFYCWLFLGYFWLVKKEKIDIVKFCVIAFLILGIFLVPKE EEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC HGKTVFLAVGQGDAAVIHTLRGRTIVVDTGPKNENYDAGRKVLAYLRQSGTGVIDLLVLT CCCEEEEEECCCCCEEHEEECCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEE HPHNDHYGGAETLIQSATVKAVLISPYLGEDQEYLELLNLLRLRKIKIYYAKTSAVISLD CCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCEEEEEC DVSLRILGPERIYSGTRSDPNNNSVVLAGKIGRKTYFFGADIEREAEEDLENQLLAYYEV CCEEEEECHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHH VKIPHHGSNFFSESFMEKLKFGYGVISVGQNNLYGFPGDKLLAALKGKGKLWRTDLEGAL HCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCEE VVENY EEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]