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The map label for this gene is dsdA

Identifier: 78044497

GI number: 78044497

Start: 57665

End: 58933

Strand: Direct

Name: dsdA

Synonym: CHY_0067

Alternate gene names: 78044497

Gene position: 57665-58933 (Clockwise)

Preceding gene: 78043041

Following gene: 78044612

Centisome position: 2.4

GC content: 43.74

Gene sequence:

>1269_bases
ATGTCCGACCTTTTAACAGGTATTAAGAATTACCAGCAGATGTTCTGGCAAAATCCCAATAAACTTTCGGCTGATGAGGC
TTTGGCCAGGATTAATTTTAGTTTTGATGATATCTTCGAGGCTCAAAAGAGACTTCAAAGATTTGCCCCTCTTATAAAAA
AGCTTTTCCCCGAGACGGAAAACGGGATTATCGAATCGCCGTTAGCAGAAATTCCCCGGATGAAACAGGAAATTGAAAAG
CTTTACGGCGGGAAAATTCACGGCCGTCTTTTCCTAAAATGCGACAACTACTTAAAAGTAGCCGGTTCTATCAAAGCCCG
GGGCGGTATTTATGAAGTGTTAAAGCATGCCGAAACCCTCTTATTAGAAAATGGACTCATTACCCTGGAGGATGATTACT
CCAAAATCGCTGAGGAGCGGTTTAAAAAATTTTTCAGTAACTACAAAGTAGCGGTGGGTTCTACCGGAAATCTCGGGTTA
TCTATTGGAATCATGGCAGCAGCTTTAGGTTTTAAGGTAGATGTCCACATGTCCCATGATGCTAAGGAGTGGAAGAAAAA
AATCCTAAGAGACCGCGGCGTAAATGTGATCGAATACCGGGAGGATTACTCTAAAGCGGTAGAAGAAGGCCGGAAAAAAG
CGGCGGCGGAGAAGAACACCTATTTTATCGATGATGAAAACTCCCGGGATTTGTTTTTGGGCTATTCTGTTGCGGCTTTA
CGGCTAAAAGACCAGTTAACGGAGCTTGGCATTGAAGTAAATAAAGAAAACCCCCTTTTTGTCTACCTGCCTTGCGGTGT
AGGTGGGGCCCCGGGAGGTATTTCCTTTGGGCTAAAAACCATCTTTAAAGACGATGTTTACTGTTATTTTGTGGAGCCCA
CCCATTCACCCTGCATGCTTTTGGGCTTGGTTACCCAGAAATTTTCCGCTATCCACGTAAGGGATTTTGGTCTCGATAAC
ATTACCGAAGCGGACGGACTGGCGGTGGGGTCTCCTTCCAAGCTCGTAGCGGAAATAGCCAATATTTTAATTGACGGGAT
TTATACCATCGAAGATGAGGAACTTTTTAAGTTGTTAGCTCTATTAAAAGACAGCGAAAACATTAAAGTTGAGCCATCGG
CAGCAGCCTCGCTAAAAGGGCCGCTTTTAGTCAATAGCAGGGCAAATGCGATCCATATTTCCTGGGCAACCGGAGGAATA
TTTATTCCGGAAGAGATTTACCGGGAAATGTATATGAGGGGTAAGAGTTACCTTAAAGATGTGTATTGA

Upstream 100 bases:

>100_bases
TAATGCCAGTAAAAGCGTCTGTTTGTATCAGGTTTAAATAATGTAATTCAAACAGCAAAAAGGAAAGCTCGGACTATAAC
TTAACTTTTGAGGTGAAAGA

Downstream 100 bases:

>100_bases
CAAATTATAAGGTTTTATGTAGAATTATGCACGGTTTGACCGCCCAAATATTAATGGGCGTTTTCTTTTTTATTAAAATT
TATGGCAGTAGGAGGAGCAG

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSDLLTGIKNYQQMFWQNPNKLSADEALARINFSFDDIFEAQKRLQRFAPLIKKLFPETENGIIESPLAEIPRMKQEIEK
LYGGKIHGRLFLKCDNYLKVAGSIKARGGIYEVLKHAETLLLENGLITLEDDYSKIAEERFKKFFSNYKVAVGSTGNLGL
SIGIMAAALGFKVDVHMSHDAKEWKKKILRDRGVNVIEYREDYSKAVEEGRKKAAAEKNTYFIDDENSRDLFLGYSVAAL
RLKDQLTELGIEVNKENPLFVYLPCGVGGAPGGISFGLKTIFKDDVYCYFVEPTHSPCMLLGLVTQKFSAIHVRDFGLDN
ITEADGLAVGSPSKLVAEIANILIDGIYTIEDEELFKLLALLKDSENIKVEPSAAASLKGPLLVNSRANAIHISWATGGI
FIPEEIYREMYMRGKSYLKDVY

Sequences:

>Translated_422_residues
MSDLLTGIKNYQQMFWQNPNKLSADEALARINFSFDDIFEAQKRLQRFAPLIKKLFPETENGIIESPLAEIPRMKQEIEK
LYGGKIHGRLFLKCDNYLKVAGSIKARGGIYEVLKHAETLLLENGLITLEDDYSKIAEERFKKFFSNYKVAVGSTGNLGL
SIGIMAAALGFKVDVHMSHDAKEWKKKILRDRGVNVIEYREDYSKAVEEGRKKAAAEKNTYFIDDENSRDLFLGYSVAAL
RLKDQLTELGIEVNKENPLFVYLPCGVGGAPGGISFGLKTIFKDDVYCYFVEPTHSPCMLLGLVTQKFSAIHVRDFGLDN
ITEADGLAVGSPSKLVAEIANILIDGIYTIEDEELFKLLALLKDSENIKVEPSAAASLKGPLLVNSRANAIHISWATGGI
FIPEEIYREMYMRGKSYLKDVY
>Mature_421_residues
SDLLTGIKNYQQMFWQNPNKLSADEALARINFSFDDIFEAQKRLQRFAPLIKKLFPETENGIIESPLAEIPRMKQEIEKL
YGGKIHGRLFLKCDNYLKVAGSIKARGGIYEVLKHAETLLLENGLITLEDDYSKIAEERFKKFFSNYKVAVGSTGNLGLS
IGIMAAALGFKVDVHMSHDAKEWKKKILRDRGVNVIEYREDYSKAVEEGRKKAAAEKNTYFIDDENSRDLFLGYSVAALR
LKDQLTELGIEVNKENPLFVYLPCGVGGAPGGISFGLKTIFKDDVYCYFVEPTHSPCMLLGLVTQKFSAIHVRDFGLDNI
TEADGLAVGSPSKLVAEIANILIDGIYTIEDEELFKLLALLKDSENIKVEPSAAASLKGPLLVNSRANAIHISWATGGIF
IPEEIYREMYMRGKSYLKDVY

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=416, Percent_Identity=53.6057692307692, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_CARHZ (Q3AFZ5)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_358939.1
- ProteinModelPortal:   Q3AFZ5
- STRING:   Q3AFZ5
- GeneID:   3727616
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0067
- NMPDR:   fig|246194.3.peg.580
- TIGR:   CHY_0067
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- BioCyc:   CHYD246194:CHY_0067-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 47309; Mature: 47178

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLLTGIKNYQQMFWQNPNKLSADEALARINFSFDDIFEAQKRLQRFAPLIKKLFPETE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NGIIESPLAEIPRMKQEIEKLYGGKIHGRLFLKCDNYLKVAGSIKARGGIYEVLKHAETL
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHH
LLENGLITLEDDYSKIAEERFKKFFSNYKVAVGSTGNLGLSIGIMAAALGFKVDVHMSHD
HHHCCEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCEEEEEEECCC
AKEWKKKILRDRGVNVIEYREDYSKAVEEGRKKAAAEKNTYFIDDENSRDLFLGYSVAAL
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHH
RLKDQLTELGIEVNKENPLFVYLPCGVGGAPGGISFGLKTIFKDDVYCYFVEPTHSPCML
HHHHHHHHCCCEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHH
LGLVTQKFSAIHVRDFGLDNITEADGLAVGSPSKLVAEIANILIDGIYTIEDEELFKLLA
HHHHHHHHCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEECHHHHHHHHH
LLKDSENIKVEPSAAASLKGPLLVNSRANAIHISWATGGIFIPEEIYREMYMRGKSYLKD
HHCCCCCCEECCCCCCCCCCCEEEECCCCEEEEEEECCCEECCHHHHHHHHHHHHHHHHC
VY
CC
>Mature Secondary Structure 
SDLLTGIKNYQQMFWQNPNKLSADEALARINFSFDDIFEAQKRLQRFAPLIKKLFPETE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NGIIESPLAEIPRMKQEIEKLYGGKIHGRLFLKCDNYLKVAGSIKARGGIYEVLKHAETL
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHH
LLENGLITLEDDYSKIAEERFKKFFSNYKVAVGSTGNLGLSIGIMAAALGFKVDVHMSHD
HHHCCEEEEECHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCEEEEEEECCC
AKEWKKKILRDRGVNVIEYREDYSKAVEEGRKKAAAEKNTYFIDDENSRDLFLGYSVAAL
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHH
RLKDQLTELGIEVNKENPLFVYLPCGVGGAPGGISFGLKTIFKDDVYCYFVEPTHSPCML
HHHHHHHHCCCEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHH
LGLVTQKFSAIHVRDFGLDNITEADGLAVGSPSKLVAEIANILIDGIYTIEDEELFKLLA
HHHHHHHHCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEECHHHHHHHHH
LLKDSENIKVEPSAAASLKGPLLVNSRANAIHISWATGGIFIPEEIYREMYMRGKSYLKD
HHCCCCCCEECCCCCCCCCCCEEEECCCCEEEEEEECCCEECCHHHHHHHHHHHHHHHHC
VY
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA