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The map label for this gene is aroC

Identifier: 78044224

GI number: 78044224

Start: 538167

End: 539321

Strand: Direct

Name: aroC

Synonym: CHY_0624

Alternate gene names: 78044224

Gene position: 538167-539321 (Clockwise)

Preceding gene: 78043133

Following gene: 78043432

Centisome position: 22.41

GC content: 50.48

Gene sequence:

>1155_bases
ATGTTTCGGTATTTAACTTCGGGGGAATCCCACGGTGAAGGATTATATGTGATTTTGGAAGGAGTGCCGGCAGGACTTAA
GGTTGACCTTGATTACATAAACCACGAACTTTCCCGCCGGCAACTGGGCTATGGCCGGGGGGAGCGGATGAAAATAGAAA
AGGATGAAGCGCAAATTTTAACAGGCGTCCGGGGAGGCTTTGCTACCGGAGCACCTATTACCATAAAGGTTAAAAACCGG
GATTATGAAAACTGGGAGAAGTTTATGCGGACCACCGGAGAAATCGAACCGGGAAGGGAGGTTACCGTGCCTCGCCCTGG
TCATGCCGATTTAGCCGGGGGGTTAAAGTACGGGCATAAAGATTTAAGGAACGTTTTGGAAAGGGCTTCGGCCCGGGAGA
CGGCGGTCCGGGTAGCTGCGGGAGCAGTTGCCAAACTTTTTTTGGCGGAGTTCGGCGTTCGGATTTACAGTCACGTATTG
AGAATAGGTTCGGTGGAAGTGGAATATCCCGGGGGTCTTCCTGAAGAAGAGCTAAAAAAAGCCGATGAACACCCCCTGCG
TTGTCTTGACGCCCAGGTTGAGGGACGGATGCTCAAATGGGTGGATCGGGCCCGGGAAAACGGGGATACTTTGGGTGGCA
TTTTTGAGGTGGTGGTGTTTGGGCTACCCCCGGGCCTGGGAAGCTACGTTCACTGGGACAGAAAATTAGATGGCCGTCTG
GCCGGAGCATTAATGGCCATTCCTTCGGCCAAAGGGGTCGAGATTGGCGATGGTATTGCTCTTGCCAATATTCCCGGACG
GATGGCGGTGGATGAGATTTATTACGAAAATGGCCACTTTTACCGGAAAACCAATAAAGCCGGGGGGTTAGAAGGCGGAG
TAACCAATGGCATGCCGTTAATAGCCAAAGTTTCCTTAAAACCCATTCCCACTCAGGTAAAGCCCTTAAAATCGGTGGAC
ATCGTTACCAAGGAAACAAAGCCGGCTCAAGTGGAACGGTCGGACATAACAGCCGTTCCGGCGGCGGGAGTAGTAGGGGA
AGCAGTTACTGCCCTGGTATTAATGGAAAGCTTTCTTGAAAAATTTGGCGGTGACCGAATCGAGGAAACAAAAAGAAACT
ATCAAAATTATCTTCAATCTATAGCCAATTATTAG

Upstream 100 bases:

>100_bases
GCCCGCCGGTTAAGGTGATGAAAAAAGCTATCGGCCTTTCTTGTTAAAGAGCCGGGAATCAAGTAAAATAGAGGTAAATT
TTACTGATGGGGGTTGTGCG

Downstream 100 bases:

>100_bases
AAGGAAAAGAGAATTTTATAGCGAAAAGTTATTATTATAGAAAGGTGAAAAAATGAACAAGCGCTTTATAGACTGTCTTG
GGGAAATGTGCCCCATACCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQILTGVRGGFATGAPITIKVKNR
DYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHKDLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVL
RIGSVEVEYPGGLPEEELKKADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRL
AGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPLIAKVSLKPIPTQVKPLKSVD
IVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLEKFGGDRIEETKRNYQNYLQSIANY

Sequences:

>Translated_384_residues
MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQILTGVRGGFATGAPITIKVKNR
DYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHKDLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVL
RIGSVEVEYPGGLPEEELKKADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRL
AGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPLIAKVSLKPIPTQVKPLKSVD
IVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLEKFGGDRIEETKRNYQNYLQSIANY
>Mature_384_residues
MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQILTGVRGGFATGAPITIKVKNR
DYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHKDLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVL
RIGSVEVEYPGGLPEEELKKADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRL
AGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPLIAKVSLKPIPTQVKPLKSVD
IVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLEKFGGDRIEETKRNYQNYLQSIANY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=366, Percent_Identity=34.9726775956284, Blast_Score=164, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6321290, Length=375, Percent_Identity=35.7333333333333, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CARHZ (Q3AEF4)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359480.1
- HSSP:   P63611
- ProteinModelPortal:   Q3AEF4
- SMR:   Q3AEF4
- STRING:   Q3AEF4
- GeneID:   3727341
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0624
- NMPDR:   fig|246194.3.peg.367
- TIGR:   CHY_0624
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   CHYD246194:CHY_0624-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42058; Mature: 42058

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQIL
CCEEECCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEECHHHHHH
TGVRGGFATGAPITIKVKNRDYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHK
HHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHCCHHCCHH
DLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVLRIGSVEVEYPGGLPEEELKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
ADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRL
CCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCHHH
AGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPL
HHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHEECCCCEEEECCCCCCCCCCCCCCCCE
IAKVSLKPIPTQVKPLKSVDIVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLE
EEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KFGGDRIEETKRNYQNYLQSIANY
HHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFRYLTSGESHGEGLYVILEGVPAGLKVDLDYINHELSRRQLGYGRGERMKIEKDEAQIL
CCEEECCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEECHHHHHH
TGVRGGFATGAPITIKVKNRDYENWEKFMRTTGEIEPGREVTVPRPGHADLAGGLKYGHK
HHCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHCCHHCCHH
DLRNVLERASARETAVRVAAGAVAKLFLAEFGVRIYSHVLRIGSVEVEYPGGLPEEELKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
ADEHPLRCLDAQVEGRMLKWVDRARENGDTLGGIFEVVVFGLPPGLGSYVHWDRKLDGRL
CCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCHHH
AGALMAIPSAKGVEIGDGIALANIPGRMAVDEIYYENGHFYRKTNKAGGLEGGVTNGMPL
HHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHEECCCCEEEECCCCCCCCCCCCCCCCE
IAKVSLKPIPTQVKPLKSVDIVTKETKPAQVERSDITAVPAAGVVGEAVTALVLMESFLE
EEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KFGGDRIEETKRNYQNYLQSIANY
HHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA