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The map label for this gene is moaC

Identifier: 78044091

GI number: 78044091

Start: 712721

End: 713194

Strand: Direct

Name: moaC

Synonym: CHY_0803

Alternate gene names: 78044091

Gene position: 712721-713194 (Clockwise)

Preceding gene: 78043321

Following gene: 78044913

Centisome position: 29.68

GC content: 46.84

Gene sequence:

>474_bases
ATGGAGCTTACCCACTTTAATGAAGAAGGACGGGCGCGAATGGTAGAGGTGACCGAAAAGCAAGAAACGGTACGGACAGC
GGTAGCTGCCGGAGAAATCACCATGCGCCCGGAAACTTTAGAATTGATTTTAGATAAAAAGGTCGCTAAAGGGGACGTGC
TGGCGGTAGCGCAGGTGGCCGGGATAATGGCGGCCAAAAAAACCGGTGATTTAATTCCGATGTGCCACCCTTTAAACTTA
ACCGGAGTGGACATAAGTTTTACTATTAAAGTGCCCGATACCATTGAAGCAAAAGCTAAAGTTACCTGTGTGGGCAAAAC
CGGGGTTGAGATGGAAGCGTTAACTGCCGTTTCCGTGACCCTTCTTACTATCTATGATATGGTGAAAGCCGTAGAAAAAG
GCATGGTGATAAAAAATATCCGGCTTTTAGAGAAAACCGGTGGTAAGAGCGGCGATTACAGAAGGGAGGAATAA

Upstream 100 bases:

>100_bases
ACCGGAGTTTTGCGGGAGGCAATTTTAAGAAAACCCAGGGCCCATGAGTTTGGCGATAAGGACTTTTTAGGAACAATGGC
CAACATAGGAGGTTAATGCG

Downstream 100 bases:

>100_bases
AAATGGGCAAGGTAGTAGCGGTAAATATCAGCGAAAAAAAAGGAATGCGCAAAAAAAATATTGAGCGGGCATATTTAAGG
GAAAACCACGGCATTGAAGG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MELTHFNEEGRARMVEVTEKQETVRTAVAAGEITMRPETLELILDKKVAKGDVLAVAQVAGIMAAKKTGDLIPMCHPLNL
TGVDISFTIKVPDTIEAKAKVTCVGKTGVEMEALTAVSVTLLTIYDMVKAVEKGMVIKNIRLLEKTGGKSGDYRREE

Sequences:

>Translated_157_residues
MELTHFNEEGRARMVEVTEKQETVRTAVAAGEITMRPETLELILDKKVAKGDVLAVAQVAGIMAAKKTGDLIPMCHPLNL
TGVDISFTIKVPDTIEAKAKVTCVGKTGVEMEALTAVSVTLLTIYDMVKAVEKGMVIKNIRLLEKTGGKSGDYRREE
>Mature_157_residues
MELTHFNEEGRARMVEVTEKQETVRTAVAAGEITMRPETLELILDKKVAKGDVLAVAQVAGIMAAKKTGDLIPMCHPLNL
TGVDISFTIKVPDTIEAKAKVTCVGKTGVEMEALTAVSVTLLTIYDMVKAVEKGMVIKNIRLLEKTGGKSGDYRREE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=157, Percent_Identity=55.4140127388535, Blast_Score=167, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=50.9554140127389, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=51.7241379310345, Blast_Score=142, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_CARHZ (Q3ADX7)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359657.1
- ProteinModelPortal:   Q3ADX7
- SMR:   Q3ADX7
- STRING:   Q3ADX7
- GeneID:   3727207
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0803
- NMPDR:   fig|246194.3.peg.990
- TIGR:   CHY_0803
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   CLSK2772302
- BioCyc:   CHYD246194:CHY_0803-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17060; Mature: 17060

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTHFNEEGRARMVEVTEKQETVRTAVAAGEITMRPETLELILDKKVAKGDVLAVAQVA
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCEEEECCHHHHHEECCCCCCCCHHHHHHHH
GIMAAKKTGDLIPMCHPLNLTGVDISFTIKVPDTIEAKAKVTCVGKTGVEMEALTAVSVT
HHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHH
LLTIYDMVKAVEKGMVIKNIRLLEKTGGKSGDYRREE
HHHHHHHHHHHHCCEEEHHEEEEHHCCCCCCCCCCCC
>Mature Secondary Structure
MELTHFNEEGRARMVEVTEKQETVRTAVAAGEITMRPETLELILDKKVAKGDVLAVAQVA
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCEEEECCHHHHHEECCCCCCCCHHHHHHHH
GIMAAKKTGDLIPMCHPLNLTGVDISFTIKVPDTIEAKAKVTCVGKTGVEMEALTAVSVT
HHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHH
LLTIYDMVKAVEKGMVIKNIRLLEKTGGKSGDYRREE
HHHHHHHHHHHHCCEEEHHEEEEHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA