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The map label for this gene is ytjP [H]

Identifier: 78043993

GI number: 78043993

Start: 1998862

End: 2000259

Strand: Direct

Name: ytjP [H]

Synonym: CHY_2216

Alternate gene names: 78043993

Gene position: 1998862-2000259 (Clockwise)

Preceding gene: 78043141

Following gene: 78042738

Centisome position: 83.23

GC content: 44.71

Gene sequence:

>1398_bases
GTGAATTTAGACAGTTACATTGAAAGCCTGAAGGAAGATATTGTTCGCACCACTCAAGAATGGATAAAAATTAAAAGCGT
GGAAGGAGAACCAAAGCCCGGAATGCCCTTTGGCGAAGGTGTAAACCAGGCTCTCTTAAAGGCTCTCGCTGACTCCGCCA
AAATGGGATTTACGACAAAAAATGTTGACGGCTATGCCGGCTATGCTGAATACGGTCAGGGGAAGGAGTTAGTAGGTATC
CTCGTCCACTTAGATGTGGTGCCCGAAGGAGACGGCTGGAGCTATGACCCTTACGGTGGTGTCATTGTCAATAACCGGAT
TTACGGCCGGGGTACGGTAGATAACAAAGGCCCGGCGGTTGCCTGCCTTTATGCCCTAAAAGCAATAAAGGATTTAAACC
TTCCGGTCTCCAAACGAGTACGGATTATTTACGGTTTAAACGAAGAATCCGGCTGGGCCTGCATGGATTACTACCGGGCC
AACGAAGAAATTCCCCAGCTTGGTTTTGCCCCGGATGCCGAATTTCCCATCATTTATGCCGAAAAAGGGATTTTGACCTT
AAAACTTGCCCGGGAATTTTCTAACCTAAAAAACGGCGAGTTAGTGTTAAAATCCTTTAAGGGCGGACTTCGAGCCAACA
TGGTGCCGGATTTTGCCGTAGCGGTTTTAGAAGGAAGTGAAAAAGCTCTAAAAACCGCTTCCGATGCCCTGGAAAATTAC
AAAAAAGAAAAAGGTTTTAAGATGGAAGCGGTAATTGAAGGCAACACCCTTACCATTAAATCCTACGGCATTTCGGCGCA
CGGCAGCCTTCCGGAAAAGGGTAAAAACGCCATAGCCCAGCTTTTAGTATTTTTGACCACTCTGCCTCTGCCCGGGGACG
ATATTTCCGCCTACTTAAATTTCTTAGCTGAAAAAATAGGTTTAACTTATAACGGAGAAAATATTGGGTTAAAACTCTCG
GATAACGTTTCAGGTAATCTTACCCTCAACCTCGGCGTCTTAGAACTTACCGAAAAAGAAGCTTACGCTGCTTTAAATAT
TCGCTACCCGGTTACCTATAAAAAAGAAGATCTCTTAAAAATCTTAGAAGAGCAAATTTCCGGTACCGGCATTTACTTAA
AAGATATCTCCGATATGGCTCCCCTATACGTACCCGAAGACCATTTCTTAGTGCAGAAACTTAAAAAAGTTTATGAAGAA
AAAACCGGCGAGCCTGCCCGGTTAATAGCCATTGGCGGCGGCACTTATGCCCGGGCTATTCCCAACGCCGTTGCTTTTGG
TCCTCTATTCCCGGGCATGGAAGAACTTGCCCACCAAAAAGACGAGTATATCGATATCGACCATTTAATTCAGATAACCA
AGATATATGCCGCAGCGATTTATGAATTAATTAAGTAG

Upstream 100 bases:

>100_bases
TTTATATCATATATCTTAACAAAATCTCTTTTAAAAAGTCAGCAAAAAAGTTAAGATATGATTGTATACAACTATAATTA
TGCTAAAAGGAGGGTATGAA

Downstream 100 bases:

>100_bases
CAAAAAGCCCTGAAGCTTTTAGCTTCAGGGCTTTTAATTCTTTAATTTTCAACAGCTACTTCTGGTTGCTGCGGCTTACT
TAAAATATTCAGCCACTTGA

Product: M20/M25/M40 family peptidase

Products: succinate; LL-2,6-diaminoheptanedioate

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNLDSYIESLKEDIVRTTQEWIKIKSVEGEPKPGMPFGEGVNQALLKALADSAKMGFTTKNVDGYAGYAEYGQGKELVGI
LVHLDVVPEGDGWSYDPYGGVIVNNRIYGRGTVDNKGPAVACLYALKAIKDLNLPVSKRVRIIYGLNEESGWACMDYYRA
NEEIPQLGFAPDAEFPIIYAEKGILTLKLAREFSNLKNGELVLKSFKGGLRANMVPDFAVAVLEGSEKALKTASDALENY
KKEKGFKMEAVIEGNTLTIKSYGISAHGSLPEKGKNAIAQLLVFLTTLPLPGDDISAYLNFLAEKIGLTYNGENIGLKLS
DNVSGNLTLNLGVLELTEKEAYAALNIRYPVTYKKEDLLKILEEQISGTGIYLKDISDMAPLYVPEDHFLVQKLKKVYEE
KTGEPARLIAIGGGTYARAIPNAVAFGPLFPGMEELAHQKDEYIDIDHLIQITKIYAAAIYELIK

Sequences:

>Translated_465_residues
MNLDSYIESLKEDIVRTTQEWIKIKSVEGEPKPGMPFGEGVNQALLKALADSAKMGFTTKNVDGYAGYAEYGQGKELVGI
LVHLDVVPEGDGWSYDPYGGVIVNNRIYGRGTVDNKGPAVACLYALKAIKDLNLPVSKRVRIIYGLNEESGWACMDYYRA
NEEIPQLGFAPDAEFPIIYAEKGILTLKLAREFSNLKNGELVLKSFKGGLRANMVPDFAVAVLEGSEKALKTASDALENY
KKEKGFKMEAVIEGNTLTIKSYGISAHGSLPEKGKNAIAQLLVFLTTLPLPGDDISAYLNFLAEKIGLTYNGENIGLKLS
DNVSGNLTLNLGVLELTEKEAYAALNIRYPVTYKKEDLLKILEEQISGTGIYLKDISDMAPLYVPEDHFLVQKLKKVYEE
KTGEPARLIAIGGGTYARAIPNAVAFGPLFPGMEELAHQKDEYIDIDHLIQITKIYAAAIYELIK
>Mature_465_residues
MNLDSYIESLKEDIVRTTQEWIKIKSVEGEPKPGMPFGEGVNQALLKALADSAKMGFTTKNVDGYAGYAEYGQGKELVGI
LVHLDVVPEGDGWSYDPYGGVIVNNRIYGRGTVDNKGPAVACLYALKAIKDLNLPVSKRVRIIYGLNEESGWACMDYYRA
NEEIPQLGFAPDAEFPIIYAEKGILTLKLAREFSNLKNGELVLKSFKGGLRANMVPDFAVAVLEGSEKALKTASDALENY
KKEKGFKMEAVIEGNTLTIKSYGISAHGSLPEKGKNAIAQLLVFLTTLPLPGDDISAYLNFLAEKIGLTYNGENIGLKLS
DNVSGNLTLNLGVLELTEKEAYAALNIRYPVTYKKEDLLKILEEQISGTGIYLKDISDMAPLYVPEDHFLVQKLKKVYEE
KTGEPARLIAIGGGTYARAIPNAVAFGPLFPGMEELAHQKDEYIDIDHLIQITKIYAAAIYELIK

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI21071039, Length=176, Percent_Identity=30.6818181818182, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.18

Molecular weight: Translated: 51080; Mature: 51080

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDSYIESLKEDIVRTTQEWIKIKSVEGEPKPGMPFGEGVNQALLKALADSAKMGFTTK
CCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEC
NVDGYAGYAEYGQGKELVGILVHLDVVPEGDGWSYDPYGGVIVNNRIYGRGTVDNKGPAV
CCCCCCCHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEECCEEEECCCCCCCCCHH
ACLYALKAIKDLNLPVSKRVRIIYGLNEESGWACMDYYRANEEIPQLGFAPDAEFPIIYA
HHHHHHHHHHHCCCCHHHCEEEEEECCCCCCCEEEHHHHCCCCCCCCCCCCCCCCCEEEE
EKGILTLKLAREFSNLKNGELVLKSFKGGLRANMVPDFAVAVLEGSEKALKTASDALENY
CCCEEEEEEHHHHHCCCCCCEEHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
KKEKGFKMEAVIEGNTLTIKSYGISAHGSLPEKGKNAIAQLLVFLTTLPLPGDDISAYLN
HHHCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FLAEKIGLTYNGENIGLKLSDNVSGNLTLNLGVLELTEKEAYAALNIRYPVTYKKEDLLK
HHHHHHCCEECCCEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEEEEECCCCCHHHHHH
ILEEQISGTGIYLKDISDMAPLYVPEDHFLVQKLKKVYEEKTGEPARLIAIGGGTYARAI
HHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHC
PNAVAFGPLFPGMEELAHQKDEYIDIDHLIQITKIYAAAIYELIK
CCHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNLDSYIESLKEDIVRTTQEWIKIKSVEGEPKPGMPFGEGVNQALLKALADSAKMGFTTK
CCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEC
NVDGYAGYAEYGQGKELVGILVHLDVVPEGDGWSYDPYGGVIVNNRIYGRGTVDNKGPAV
CCCCCCCHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCEEECCEEEECCCCCCCCCHH
ACLYALKAIKDLNLPVSKRVRIIYGLNEESGWACMDYYRANEEIPQLGFAPDAEFPIIYA
HHHHHHHHHHHCCCCHHHCEEEEEECCCCCCCEEEHHHHCCCCCCCCCCCCCCCCCEEEE
EKGILTLKLAREFSNLKNGELVLKSFKGGLRANMVPDFAVAVLEGSEKALKTASDALENY
CCCEEEEEEHHHHHCCCCCCEEHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
KKEKGFKMEAVIEGNTLTIKSYGISAHGSLPEKGKNAIAQLLVFLTTLPLPGDDISAYLN
HHHCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
FLAEKIGLTYNGENIGLKLSDNVSGNLTLNLGVLELTEKEAYAALNIRYPVTYKKEDLLK
HHHHHHCCEECCCEEEEEEECCCCCEEEEEEEEEEEECCCCEEEEEEEECCCCCHHHHHH
ILEEQISGTGIYLKDISDMAPLYVPEDHFLVQKLKKVYEEKTGEPARLIAIGGGTYARAI
HHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHC
PNAVAFGPLFPGMEELAHQKDEYIDIDHLIQITKIYAAAIYELIK
CCHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-LL-2,6-diaminoheptanedioate; H2O

Specific reaction: N-succinyl-LL-2,6-diaminoheptanedioate + H2O = succinate + LL-2,6-diaminoheptanedioate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]