BacMap

Definition	Carboxydothermus hydrogenoformans Z-2901 chromosome, complete genome.
Accession	NC_007503
Length	2,401,520

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The map label for this gene is ftsH [H]

Identifier: 78043977

GI number: 78043977

Start: 180029

End: 181888

Strand: Direct

Name: ftsH [H]

Synonym: CHY_0214

Alternate gene names: 78043977

Gene position: 180029-181888 (Clockwise)

Preceding gene: 78043578

Following gene: 78044290

Centisome position: 7.5

GC content: 47.47

Gene sequence:

>1860_bases
TTGAATAAAGTATTAAAAAATTTAGCAATTTATTTGTTGATTGTTTTGGTTGCAGTAATGCTCATAAACTATTCCCGGCC
GTCGGCAACTTCTATTCGCGATTTGAAATATGATGAGTTTTATAGCCTTTTGGAAAAAGGGCAGGTAGCGTCGGTAGCGA
TTCAGACGGACCGGACAATTAATGAAATTTCAGGGGTTTTAAGGGATGGAACCAGGTTTAAAACCCGGGGGCCCCTGGAA
GATGCTGAACTATATAAAGATCTAAAAAAGATGAATGTTACGGTAGAAATTATGCCGCCGAAAGAACCGGCCTTTTGGGC
CAACCTTTTAAGTTCCCTGTTACCGGTCCTTTTAATGGTGGGTTTGTTCTTTTTCTTTATGCAACAGGCCCAGGGCGGGG
GTAACCGGGTGATGTCCTTCGGCAAAAGCCGGGCCAAGCTGCATACCGATGAGAAAAAGCGGGTTACCTTTGCCGATGTG
GCTGGGATTGATGAAGTAAAGGAAGAATTGGCGGAAATCGTCGAGTTTTTGAAAAACCCCCGGAAGTATAACGAATTAGG
AGCCAGAATTCCCAAGGGCGTTCTCCTTTTTGGCCAACCGGGTACCGGGAAAACTTTGCTGGCCCGGGCAATAGCCGGTG
AAGCGGGGGTGCCGTTTTTTAGCATTAGCGGCTCCGATTTTGTGGAGATGTTTGTAGGGGTTGGTGCTTCCCGGGTAAGG
GATCTTTTTGAGCAGGCCAAGAAAAATGCTCCCTGCATTGTTTTTATTGATGAGATTGATGCTGTTGGTCGGCAGCGGGG
AGCGGGGTTAGGTGGCGGTCACGACGAACGGGAGCAAACCTTAAACCAGCTGTTGGTGGAAATGGACGGCTTTAATTCCA
ACGAAGGAATTATCATTATTGCCGCTACCAACCGACCGGACATTTTAGATCCAGCCCTTTTGCGGCCGGGACGTTTCGAC
CGACACATAGTGGTGGATACTCCGGATATTAACGGTCGCAAGGAAATCTTAAAAGTTCACGTTAAAGGGAAACCGCTGGG
AGATGATGTGGATTTGGATGTTCTGGCCCGGCGTACCCCAGGTTTTACCGGTGCTGATTTAGCAAATATGGTTAATGAAG
CGGCCCTGCTTGCTGCTCGCCGCAATAAGAAAGTTATTAACATGGAAGAGATGGAAGAAGCAATTGAAAGGGTTATTGCC
GGTCCGGAAAAGAAAAGCAAGGTCATTTCCGAACGGGAGAAGCGGCTTGTAGCTTACCATGAGGCGGGCCATGCCATGGT
CGGTTACCTCCTTCCCCATACCGACCCGGTCCACAAGATTTCCATTATTCCCCGGGGACGGGCCGGGGGCTATACTTTAC
TGTTACCCGAAGAAGACCGTTCGTACATGACAAAATCCCAGCTTCTCGATGAAATTACCATGCTTTTGGGAGGTCGGGTA
GCGGAGGCTCTGGTTTTAGAAGACATTAGCACCGGTGCCCGTAACGATCTGGAGCGGGCTACCGAAACGGCCAGGCGCAT
GGTTATGGAATACGGAATGAGCGAAGAATTGGGCCCTCTGACCTTTGGTAAAGGTACCGAAGCGGTGTTTTTAGGCCGGG
ATTTGGCCCGGGATAGAAATTATTCCGAAGAAATAGCCTATACCATTGATAAAGAAGTAAGAAAAATTATTGATAGCTGT
TATAGCCGGGCGGAGGAGATTTTAAAGAAAAATATTAATGTGCTTCACCTTGTAGCGACAAAACTTATGGAAGTGGAAAC
GATGGAAGGGGAAGAGTTTGAAAAGTTAATGAAAGAAAATGGCTTAACCAAGCCCAGGGTAAATGGAAATAACGATTCAC
CTGCGGATGTTCTCCAGTAG

Upstream 100 bases:

>100_bases
TATTCCCTTTGCGGTAAACCTTGAATTATTGAAAAGTTGTTGAAATTATGATAAAATTTTGTAGCATAATGATGGAAAGC
TGTGAGAGGAGTGCTCAACT

Downstream 100 bases:

>100_bases
TTAGAAAGCCTCCCGTTTTCCGGGAGGCTTTTCCAAATACAGAAAAAGGGGGAGAATATTTTCTTATGGAACGAACCTTT
ATCATGGTAAAACCCGATGG

Product: cell division protein FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MNKVLKNLAIYLLIVLVAVMLINYSRPSATSIRDLKYDEFYSLLEKGQVASVAIQTDRTINEISGVLRDGTRFKTRGPLE
DAELYKDLKKMNVTVEIMPPKEPAFWANLLSSLLPVLLMVGLFFFFMQQAQGGGNRVMSFGKSRAKLHTDEKKRVTFADV
AGIDEVKEELAEIVEFLKNPRKYNELGARIPKGVLLFGQPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVR
DLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFNSNEGIIIIAATNRPDILDPALLRPGRFD
RHIVVDTPDINGRKEILKVHVKGKPLGDDVDLDVLARRTPGFTGADLANMVNEAALLAARRNKKVINMEEMEEAIERVIA
GPEKKSKVISEREKRLVAYHEAGHAMVGYLLPHTDPVHKISIIPRGRAGGYTLLLPEEDRSYMTKSQLLDEITMLLGGRV
AEALVLEDISTGARNDLERATETARRMVMEYGMSEELGPLTFGKGTEAVFLGRDLARDRNYSEEIAYTIDKEVRKIIDSC
YSRAEEILKKNINVLHLVATKLMEVETMEGEEFEKLMKENGLTKPRVNGNNDSPADVLQ

Sequences:

>Translated_619_residues
MNKVLKNLAIYLLIVLVAVMLINYSRPSATSIRDLKYDEFYSLLEKGQVASVAIQTDRTINEISGVLRDGTRFKTRGPLE
DAELYKDLKKMNVTVEIMPPKEPAFWANLLSSLLPVLLMVGLFFFFMQQAQGGGNRVMSFGKSRAKLHTDEKKRVTFADV
AGIDEVKEELAEIVEFLKNPRKYNELGARIPKGVLLFGQPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVR
DLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFNSNEGIIIIAATNRPDILDPALLRPGRFD
RHIVVDTPDINGRKEILKVHVKGKPLGDDVDLDVLARRTPGFTGADLANMVNEAALLAARRNKKVINMEEMEEAIERVIA
GPEKKSKVISEREKRLVAYHEAGHAMVGYLLPHTDPVHKISIIPRGRAGGYTLLLPEEDRSYMTKSQLLDEITMLLGGRV
AEALVLEDISTGARNDLERATETARRMVMEYGMSEELGPLTFGKGTEAVFLGRDLARDRNYSEEIAYTIDKEVRKIIDSC
YSRAEEILKKNINVLHLVATKLMEVETMEGEEFEKLMKENGLTKPRVNGNNDSPADVLQ
>Mature_619_residues
MNKVLKNLAIYLLIVLVAVMLINYSRPSATSIRDLKYDEFYSLLEKGQVASVAIQTDRTINEISGVLRDGTRFKTRGPLE
DAELYKDLKKMNVTVEIMPPKEPAFWANLLSSLLPVLLMVGLFFFFMQQAQGGGNRVMSFGKSRAKLHTDEKKRVTFADV
AGIDEVKEELAEIVEFLKNPRKYNELGARIPKGVLLFGQPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVR
DLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFNSNEGIIIIAATNRPDILDPALLRPGRFD
RHIVVDTPDINGRKEILKVHVKGKPLGDDVDLDVLARRTPGFTGADLANMVNEAALLAARRNKKVINMEEMEEAIERVIA
GPEKKSKVISEREKRLVAYHEAGHAMVGYLLPHTDPVHKISIIPRGRAGGYTLLLPEEDRSYMTKSQLLDEITMLLGGRV
AEALVLEDISTGARNDLERATETARRMVMEYGMSEELGPLTFGKGTEAVFLGRDLARDRNYSEEIAYTIDKEVRKIIDSC
YSRAEEILKKNINVLHLVATKLMEVETMEGEEFEKLMKENGLTKPRVNGNNDSPADVLQ

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=502, Percent_Identity=50.199203187251, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI4507173, Length=613, Percent_Identity=39.4779771615008, Blast_Score=418, Evalue=1e-117,
Organism=Homo sapiens, GI21327685, Length=446, Percent_Identity=47.5336322869955, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI7657689, Length=446, Percent_Identity=47.5336322869955, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=43.3070866141732, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI6005942, Length=229, Percent_Identity=44.1048034934498, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=42.4489795918367, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI24497435, Length=257, Percent_Identity=41.2451361867704, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI21361144, Length=260, Percent_Identity=42.6923076923077, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=39.6078431372549, Blast_Score=202, Evalue=9e-52,
Organism=Homo sapiens, GI89064750, Length=260, Percent_Identity=40.3846153846154, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI5729991, Length=260, Percent_Identity=40.3846153846154, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI24430155, Length=260, Percent_Identity=40.3846153846154, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=40.3636363636364, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=40.3636363636364, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=43.1111111111111, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI229577436, Length=250, Percent_Identity=42.4, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4505725, Length=226, Percent_Identity=41.5929203539823, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI40806173, Length=302, Percent_Identity=38.4105960264901, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI24497618, Length=236, Percent_Identity=41.5254237288136, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI194018488, Length=269, Percent_Identity=37.9182156133829, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI153792536, Length=236, Percent_Identity=39.4067796610169, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI5901990, Length=252, Percent_Identity=36.9047619047619, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI7019569, Length=242, Percent_Identity=36.7768595041322, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI14149767, Length=252, Percent_Identity=35.3174603174603, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI62177112, Length=252, Percent_Identity=35.3174603174603, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=36.2869198312236, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI17865802, Length=252, Percent_Identity=36.5079365079365, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI31377644, Length=234, Percent_Identity=37.6068376068376, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI11875211, Length=250, Percent_Identity=38.8, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI40806170, Length=250, Percent_Identity=38.8, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI31742536, Length=231, Percent_Identity=35.0649350649351, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI112789543, Length=231, Percent_Identity=35.0649350649351, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI156564401, Length=237, Percent_Identity=37.5527426160338, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI310125282, Length=237, Percent_Identity=37.1308016877637, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI310125280, Length=237, Percent_Identity=37.1308016877637, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI64084766, Length=226, Percent_Identity=29.646017699115, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI116292174, Length=265, Percent_Identity=29.0566037735849, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4757852, Length=158, Percent_Identity=31.6455696202532, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI119964730, Length=158, Percent_Identity=31.6455696202532, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789568, Length=621, Percent_Identity=52.8180354267311, Blast_Score=663, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=626, Percent_Identity=44.5686900958466, Blast_Score=459, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17554264, Length=447, Percent_Identity=46.7561521252796, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115534323, Length=454, Percent_Identity=44.7136563876652, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=44.4444444444444, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17532375, Length=231, Percent_Identity=43.7229437229437, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=42.7450980392157, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI25144281, Length=257, Percent_Identity=42.0233463035019, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI25144278, Length=257, Percent_Identity=42.0233463035019, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=43.6734693877551, Blast_Score=208, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17531535, Length=234, Percent_Identity=44.4444444444444, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=40.5511811023622, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=40.5511811023622, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17505546, Length=259, Percent_Identity=42.4710424710425, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=260, Percent_Identity=41.5384615384615, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17554784, Length=254, Percent_Identity=40.1574803149606, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17508053, Length=257, Percent_Identity=39.6887159533074, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17537217, Length=258, Percent_Identity=39.1472868217054, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17570397, Length=166, Percent_Identity=49.3975903614458, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32566590, Length=166, Percent_Identity=49.3975903614458, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25153574, Length=232, Percent_Identity=39.2241379310345, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=244, Percent_Identity=38.9344262295082, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193206114, Length=244, Percent_Identity=38.9344262295082, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=244, Percent_Identity=38.9344262295082, Blast_Score=159, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI193209502, Length=232, Percent_Identity=39.2241379310345, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI86561515, Length=261, Percent_Identity=36.7816091954023, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17508421, Length=264, Percent_Identity=39.0151515151515, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32563584, Length=267, Percent_Identity=38.5767790262172, Blast_Score=145, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17562804, Length=231, Percent_Identity=34.6320346320346, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=233, Percent_Identity=39.4849785407725, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=219, Percent_Identity=37.8995433789954, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI133901662, Length=216, Percent_Identity=38.4259259259259, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17560432, Length=228, Percent_Identity=35.9649122807018, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=230, Percent_Identity=33.0434782608696, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17541224, Length=230, Percent_Identity=33.0434782608696, Blast_Score=115, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6320854, Length=510, Percent_Identity=49.0196078431373, Blast_Score=478, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6323736, Length=501, Percent_Identity=49.3013972055888, Blast_Score=471, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6325281, Length=461, Percent_Identity=45.7700650759219, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=41.7624521072797, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320077, Length=247, Percent_Identity=42.914979757085, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6324691, Length=270, Percent_Identity=42.962962962963, Blast_Score=213, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6320197, Length=311, Percent_Identity=36.0128617363344, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=42.0408163265306, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6324833, Length=249, Percent_Identity=41.3654618473896, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6320602, Length=249, Percent_Identity=42.570281124498, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322994, Length=247, Percent_Identity=39.6761133603239, Blast_Score=190, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6323429, Length=255, Percent_Identity=39.6078431372549, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6324000, Length=237, Percent_Identity=40.084388185654, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6322651, Length=240, Percent_Identity=37.0833333333333, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=40.2542372881356, Blast_Score=167, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6325431, Length=246, Percent_Identity=36.9918699186992, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6321465, Length=239, Percent_Identity=37.2384937238494, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6325183, Length=246, Percent_Identity=35.3658536585366, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320887, Length=259, Percent_Identity=33.5907335907336, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574878, Length=617, Percent_Identity=44.8946515397083, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24665814, Length=612, Percent_Identity=45.2614379084967, Blast_Score=476, Evalue=1e-134,
Organism=Drosophila melanogaster, GI24658770, Length=494, Percent_Identity=44.9392712550607, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24639391, Length=450, Percent_Identity=47.1111111111111, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=43.7007874015748, Blast_Score=219, Evalue=7e-57,
Organism=Drosophila melanogaster, GI17137560, Length=232, Percent_Identity=42.2413793103448, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI161076488, Length=232, Percent_Identity=42.2413793103448, Blast_Score=212, Evalue=7e-55,
Organism=Drosophila melanogaster, GI161076486, Length=232, Percent_Identity=42.2413793103448, Blast_Score=212, Evalue=7e-55,
Organism=Drosophila melanogaster, GI45554047, Length=170, Percent_Identity=57.6470588235294, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI281365776, Length=232, Percent_Identity=45.2586206896552, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24660075, Length=232, Percent_Identity=45.2586206896552, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI45552965, Length=232, Percent_Identity=45.2586206896552, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI19920408, Length=257, Percent_Identity=41.2451361867704, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17738151, Length=255, Percent_Identity=42.3529411764706, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281361487, Length=265, Percent_Identity=39.622641509434, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=41.6326530612245, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=40.7843137254902, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI18860063, Length=264, Percent_Identity=39.3939393939394, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24640100, Length=255, Percent_Identity=40, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI19921202, Length=253, Percent_Identity=38.7351778656126, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=38.4313725490196, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=44.7368421052632, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=38.3064516129032, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24656825, Length=238, Percent_Identity=39.4957983193277, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281363136, Length=236, Percent_Identity=38.135593220339, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI78707192, Length=236, Percent_Identity=38.135593220339, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21355121, Length=260, Percent_Identity=34.6153846153846, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI18859657, Length=237, Percent_Identity=39.2405063291139, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI281360136, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644411, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360142, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357333, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360146, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360138, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360144, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360140, Length=261, Percent_Identity=34.8659003831418, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644145, Length=252, Percent_Identity=35.7142857142857, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20129423, Length=234, Percent_Identity=37.6068376068376, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI20129529, Length=246, Percent_Identity=36.5853658536585, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571849, Length=245, Percent_Identity=38.7755102040816, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571847, Length=245, Percent_Identity=38.7755102040816, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24581396, Length=289, Percent_Identity=34.9480968858132, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864540, Length=218, Percent_Identity=38.9908256880734, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28573010, Length=218, Percent_Identity=37.6146788990826, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24639486, Length=290, Percent_Identity=29.3103448275862, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI20129417, Length=154, Percent_Identity=33.1168831168831, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583262, Length=154, Percent_Identity=33.1168831168831, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 68773; Mature: 68773

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVLKNLAIYLLIVLVAVMLINYSRPSATSIRDLKYDEFYSLLEKGQVASVAIQTDRTI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCEEEEEEECCCCH
NEISGVLRDGTRFKTRGPLEDAELYKDLKKMNVTVEIMPPKEPAFWANLLSSLLPVLLMV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GLFFFFMQQAQGGGNRVMSFGKSRAKLHTDEKKRVTFADVAGIDEVKEELAEIVEFLKNP
HHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCHHCEEHHHHCCHHHHHHHHHHHHHHHHCC
RKYNELGARIPKGVLLFGQPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVR
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCHHHHH
DLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFNSNEGIIII
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
AATNRPDILDPALLRPGRFDRHIVVDTPDINGRKEILKVHVKGKPLGDDVDLDVLARRTP
EECCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCC
GFTGADLANMVNEAALLAARRNKKVINMEEMEEAIERVIAGPEKKSKVISEREKRLVAYH
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EAGHAMVGYLLPHTDPVHKISIIPRGRAGGYTLLLPEEDRSYMTKSQLLDEITMLLGGRV
HCCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHH
AEALVLEDISTGARNDLERATETARRMVMEYGMSEELGPLTFGKGTEAVFLGRDLARDRN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHCCC
YSEEIAYTIDKEVRKIIDSCYSRAEEILKKNINVLHLVATKLMEVETMEGEEFEKLMKEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
GLTKPRVNGNNDSPADVLQ
CCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MNKVLKNLAIYLLIVLVAVMLINYSRPSATSIRDLKYDEFYSLLEKGQVASVAIQTDRTI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCEEEEEEECCCCH
NEISGVLRDGTRFKTRGPLEDAELYKDLKKMNVTVEIMPPKEPAFWANLLSSLLPVLLMV
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
GLFFFFMQQAQGGGNRVMSFGKSRAKLHTDEKKRVTFADVAGIDEVKEELAEIVEFLKNP
HHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCHHCEEHHHHCCHHHHHHHHHHHHHHHHCC
RKYNELGARIPKGVLLFGQPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVR
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCHHHHH
DLFEQAKKNAPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFNSNEGIIII
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
AATNRPDILDPALLRPGRFDRHIVVDTPDINGRKEILKVHVKGKPLGDDVDLDVLARRTP
EECCCCCCCCHHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCC
GFTGADLANMVNEAALLAARRNKKVINMEEMEEAIERVIAGPEKKSKVISEREKRLVAYH
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EAGHAMVGYLLPHTDPVHKISIIPRGRAGGYTLLLPEEDRSYMTKSQLLDEITMLLGGRV
HCCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHH
AEALVLEDISTGARNDLERATETARRMVMEYGMSEELGPLTFGKGTEAVFLGRDLARDRN
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHCCC
YSEEIAYTIDKEVRKIIDSCYSRAEEILKKNINVLHLVATKLMEVETMEGEEFEKLMKEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
GLTKPRVNGNNDSPADVLQ
CCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA