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The map label for this gene is atoS [H]

Identifier: 78043927

GI number: 78043927

Start: 264586

End: 266289

Strand: Direct

Name: atoS [H]

Synonym: CHY_0302

Alternate gene names: 78043927

Gene position: 264586-266289 (Clockwise)

Preceding gene: 78043524

Following gene: 78042967

Centisome position: 11.02

GC content: 38.32

Gene sequence:

>1704_bases
GTGAGGGGTATTAAAGGCAGGTATTTTTACCTGACCCTTTTGTTGGTGCTGCCATTAGTGGTGCAGGGAACGGTCATGTA
TTATTTTTTATACCTCGAAATACCGGAGTTATCGGAAAAAAATTTAACATATGTTGCGGTACATATGGCGAAAGAAATTG
AGAAAGACCTAACGGATATAGATATAAATAATTTGGAAATTGCCGAGTTAAACGAAATAAATTTAATTTTAACTCATTTT
CCCGATATGATGATAAGTTTTATAAAATATCCTAATTTAGAAATTATAGCTCACTATTCCAATAAAAACGGCAAATTAGC
TAAAGATAACGAAATAATCGGTGGGGTACTTACCGGAGAAGTTAAAGATATTATAATCAAAAAGCGCTATCCTTATTTTG
GTAAGCTAAGCTTAGCCGACGGGAAAGCCTATGTTTACCTCCAACCGGTTTATGTGAAGGGAGAGCTGGTGGGTTTTGTT
CTTACCCACCAAAATCGAAATTATCTATCGGTAGTGGTTGGCGAAATTTTAAGGCTTACCGGAACGGTGCTATTTTTAAT
GCTCCTGGTGGGAATAGGGTATAGTTTGCATTATGTTTTTTTAAACGATCGGAGGACTATTGCCCTTACAAAATCTAACT
GGGATTTGCAGCGGAAATTAAATGCCGTTTTAGAAAATGCGCAAACGGGGATTGTTTTAGTTGACAGGGATTTAACTATT
ACTTACATAAATCCCATGGCGGAAGATTTTTTTAAGATTTCTTTTGCAGAAGCTGTTGGAAAACAGTACGATGAATTTAT
CAAAAGCTATATTATAACCGATGAGGAGAAAAAGTCATCATTTTTAGTGCATACTTTAAAAACCGGAAATACCGTTTATA
AAAAAACAATAACCTTTAAAGTTCTGGGAGAAATGCGTTTGGGGGAAGTTTGCACGGGAATCATCCAAAATAATTTGGGA
CAAATTGACGGAGCTTTTTTATTTATCCAGGACATAACCGATAAAAGACAGAAGGAAGAGTTAGCTGCCAAAACCCTGCA
GTTAGCAGCAGCGGGTGAAATTATGTCGGAACTTACCCACGAATTAAAAAATGCCTTTATGGTGTTAACCGGTTTATCAA
AACTTTGTCAGGATGGACGGCCCGAGTTAAAAATGCTTGATGAGGAAATAAATCGGCTGTACCGCTTGACTACTGATTTT
CTTAGCTTAACCAGAGCTTACCGGGCTAAAAAAGAACGTTTTGATTTTCAACAGTTAGTGGTGGAAGTATTAGCCCTTGT
TGATAAGGAAGCTCGTAAACAAAAGGTAAAAATTGAGACTTTTCTCCATTACCCGCCCTATTTAAAGGGCGATAGGAATC
TTTTAAAACAAGCGCTCTTGAATGTTTTATTAAACGCCGTGGAAGCTATGGAAGGGGGAGGGGTTCTTAAGGTTTACCTG
GACTACAACGTTAAAAGCCAGGAAATAGTTTTAACAGTGGCCGATAGCGGTCCCGGTATACCTCCGGAAATTCTGCAAAA
AATTTGCCAGCCTTTCTTTACTACCAAGGAGAGGGGGACCGGCCTGGGGTTACCTTTTACCAAAAGGGTAGTGGAATATC
ACTTGGGAAAGTTAATGATTAAAAGCGAAGTGGGCAAAGGAACGTGGGTAATAATTACTTTACCGGTAGAGGAGAATATC
CATGAAAAAGTCCAGGTGGTATGA

Upstream 100 bases:

>100_bases
TTGCTGCGAACCCGGTTTATTTTTTTAGCTAAAGCAGGAAAAATTAAACTAATGTAGAAGAGAATAGTGAAAAATAATCA
GAAAATTTTACCAACAGGGA

Downstream 100 bases:

>100_bases
AATAGTAAGTGGCAGAAGAGGCTACCGGCAGAATCGGTGGGCATTTTTTAGGTATTGTTCTCGGTAAAAGCTTTCGATAG
TAATGCACAACTCCTTTTTT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MRGIKGRYFYLTLLLVLPLVVQGTVMYYFLYLEIPELSEKNLTYVAVHMAKEIEKDLTDIDINNLEIAELNEINLILTHF
PDMMISFIKYPNLEIIAHYSNKNGKLAKDNEIIGGVLTGEVKDIIIKKRYPYFGKLSLADGKAYVYLQPVYVKGELVGFV
LTHQNRNYLSVVVGEILRLTGTVLFLMLLVGIGYSLHYVFLNDRRTIALTKSNWDLQRKLNAVLENAQTGIVLVDRDLTI
TYINPMAEDFFKISFAEAVGKQYDEFIKSYIITDEEKKSSFLVHTLKTGNTVYKKTITFKVLGEMRLGEVCTGIIQNNLG
QIDGAFLFIQDITDKRQKEELAAKTLQLAAAGEIMSELTHELKNAFMVLTGLSKLCQDGRPELKMLDEEINRLYRLTTDF
LSLTRAYRAKKERFDFQQLVVEVLALVDKEARKQKVKIETFLHYPPYLKGDRNLLKQALLNVLLNAVEAMEGGGVLKVYL
DYNVKSQEIVLTVADSGPGIPPEILQKICQPFFTTKERGTGLGLPFTKRVVEYHLGKLMIKSEVGKGTWVIITLPVEENI
HEKVQVV

Sequences:

>Translated_567_residues
MRGIKGRYFYLTLLLVLPLVVQGTVMYYFLYLEIPELSEKNLTYVAVHMAKEIEKDLTDIDINNLEIAELNEINLILTHF
PDMMISFIKYPNLEIIAHYSNKNGKLAKDNEIIGGVLTGEVKDIIIKKRYPYFGKLSLADGKAYVYLQPVYVKGELVGFV
LTHQNRNYLSVVVGEILRLTGTVLFLMLLVGIGYSLHYVFLNDRRTIALTKSNWDLQRKLNAVLENAQTGIVLVDRDLTI
TYINPMAEDFFKISFAEAVGKQYDEFIKSYIITDEEKKSSFLVHTLKTGNTVYKKTITFKVLGEMRLGEVCTGIIQNNLG
QIDGAFLFIQDITDKRQKEELAAKTLQLAAAGEIMSELTHELKNAFMVLTGLSKLCQDGRPELKMLDEEINRLYRLTTDF
LSLTRAYRAKKERFDFQQLVVEVLALVDKEARKQKVKIETFLHYPPYLKGDRNLLKQALLNVLLNAVEAMEGGGVLKVYL
DYNVKSQEIVLTVADSGPGIPPEILQKICQPFFTTKERGTGLGLPFTKRVVEYHLGKLMIKSEVGKGTWVIITLPVEENI
HEKVQVV
>Mature_567_residues
MRGIKGRYFYLTLLLVLPLVVQGTVMYYFLYLEIPELSEKNLTYVAVHMAKEIEKDLTDIDINNLEIAELNEINLILTHF
PDMMISFIKYPNLEIIAHYSNKNGKLAKDNEIIGGVLTGEVKDIIIKKRYPYFGKLSLADGKAYVYLQPVYVKGELVGFV
LTHQNRNYLSVVVGEILRLTGTVLFLMLLVGIGYSLHYVFLNDRRTIALTKSNWDLQRKLNAVLENAQTGIVLVDRDLTI
TYINPMAEDFFKISFAEAVGKQYDEFIKSYIITDEEKKSSFLVHTLKTGNTVYKKTITFKVLGEMRLGEVCTGIIQNNLG
QIDGAFLFIQDITDKRQKEELAAKTLQLAAAGEIMSELTHELKNAFMVLTGLSKLCQDGRPELKMLDEEINRLYRLTTDF
LSLTRAYRAKKERFDFQQLVVEVLALVDKEARKQKVKIETFLHYPPYLKGDRNLLKQALLNVLLNAVEAMEGGGVLKVYL
DYNVKSQEIVLTVADSGPGIPPEILQKICQPFFTTKERGTGLGLPFTKRVVEYHLGKLMIKSEVGKGTWVIITLPVEENI
HEKVQVV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=357, Percent_Identity=29.1316526610644, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=31.1111111111111, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=365, Percent_Identity=24.1095890410959, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=26.5217391304348, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=387, Percent_Identity=23.7726098191214, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=24.4813278008299, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=369, Percent_Identity=21.9512195121951, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=25.0965250965251, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64503; Mature: 64503

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGIKGRYFYLTLLLVLPLVVQGTVMYYFLYLEIPELSEKNLTYVAVHMAKEIEKDLTDI
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCC
DINNLEIAELNEINLILTHFPDMMISFIKYPNLEIIAHYSNKNGKLAKDNEIIGGVLTGE
CCCCEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCEECCCCEECEEEECC
VKDIIIKKRYPYFGKLSLADGKAYVYLQPVYVKGELVGFVLTHQNRNYLSVVVGEILRLT
HHHHHEECCCCCCEEEEECCCCEEEEEEEEEEECEEEEEEEEECCCCHHHHHHHHHHHHH
GTVLFLMLLVGIGYSLHYVFLNDRRTIALTKSNWDLQRKLNAVLENAQTGIVLVDRDLTI
HHHHHHHHHHHCCCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCEEE
TYINPMAEDFFKISFAEAVGKQYDEFIKSYIITDEEKKSSFLVHTLKTGNTVYKKTITFK
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEE
VLGEMRLGEVCTGIIQNNLGQIDGAFLFIQDITDKRQKEELAAKTLQLAAAGEIMSELTH
EECCCHHHHHHHHHHHCCCCCCCCEEEEEECHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKNAFMVLTGLSKLCQDGRPELKMLDEEINRLYRLTTDFLSLTRAYRAKKERFDFQQLV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VEVLALVDKEARKQKVKIETFLHYPPYLKGDRNLLKQALLNVLLNAVEAMEGGGVLKVYL
HHHHHHHCHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DYNVKSQEIVLTVADSGPGIPPEILQKICQPFFTTKERGTGLGLPFTKRVVEYHLGKLMI
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
KSEVGKGTWVIITLPVEENIHEKVQVV
EECCCCCEEEEEEEECCCCCHHHHCCC
>Mature Secondary Structure
MRGIKGRYFYLTLLLVLPLVVQGTVMYYFLYLEIPELSEKNLTYVAVHMAKEIEKDLTDI
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCC
DINNLEIAELNEINLILTHFPDMMISFIKYPNLEIIAHYSNKNGKLAKDNEIIGGVLTGE
CCCCEEEEECCCEEEEEHHHHHHHHHHHCCCCEEEEEEEECCCCCEECCCCEECEEEECC
VKDIIIKKRYPYFGKLSLADGKAYVYLQPVYVKGELVGFVLTHQNRNYLSVVVGEILRLT
HHHHHEECCCCCCEEEEECCCCEEEEEEEEEEECEEEEEEEEECCCCHHHHHHHHHHHHH
GTVLFLMLLVGIGYSLHYVFLNDRRTIALTKSNWDLQRKLNAVLENAQTGIVLVDRDLTI
HHHHHHHHHHHCCCEEEEEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCEEE
TYINPMAEDFFKISFAEAVGKQYDEFIKSYIITDEEKKSSFLVHTLKTGNTVYKKTITFK
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEEEEE
VLGEMRLGEVCTGIIQNNLGQIDGAFLFIQDITDKRQKEELAAKTLQLAAAGEIMSELTH
EECCCHHHHHHHHHHHCCCCCCCCEEEEEECHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKNAFMVLTGLSKLCQDGRPELKMLDEEINRLYRLTTDFLSLTRAYRAKKERFDFQQLV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VEVLALVDKEARKQKVKIETFLHYPPYLKGDRNLLKQALLNVLLNAVEAMEGGGVLKVYL
HHHHHHHCHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DYNVKSQEIVLTVADSGPGIPPEILQKICQPFFTTKERGTGLGLPFTKRVVEYHLGKLMI
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
KSEVGKGTWVIITLPVEENIHEKVQVV
EECCCCCEEEEEEEECCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]