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The map label for this gene is argS

Identifier: 78043915

GI number: 78043915

Start: 106601

End: 108274

Strand: Direct

Name: argS

Synonym: CHY_0124

Alternate gene names: 78043915

Gene position: 106601-108274 (Clockwise)

Preceding gene: 78044417

Following gene: 78044367

Centisome position: 4.44

GC content: 46.18

Gene sequence:

>1674_bases
GTGGAGTATCTTTTACAGAGAATTACGGGGGAGATTGCCGGCAGCTTAAGAAGAGCAGCAGTAAAGGCGGGATATTTGGA
TGCCGAGGACGAGTTAGCCTTTGAACTGGAAAAACCCAAGGAAAAAGCCCACGGTGATTTAGCCACTAACTTAGCAATGC
TTCTTACCAAAAAGGCGCGGAAAAATCCGCGGGAAATCGCAGCGACCTTGCTAGAATACTTAGAGATTCCTGCGGTAGTG
GAACGGGTGGAGATTGCCGGTCCGGGATTTATAAACTTTTACTTTAAAAAAGATTGGGTCGTTGCCGTAATTCCGGAAAT
TTTAAGCTTTGGGGAGAAATACGGACGCTTGGCTATAGGAGCGGGGAAGAGAGTTCAGGTAGAGTTTGTTTCGGCTAATC
CCACAGGCCTTCTTCATATGGGTAACGGCCGGGGAGCTGCTCTGGGGGATATCCTTGCCAATATTTTAACGGAAGCGGGT
TATGAAGTATCGAGGGAGTATTACATTAACGATGCGGGCAATCAAATTGAAAACTTTAACAAATCGGTGGAGGCCCGGTA
TTTAGAGCTATTAGGGTATAAGGTGGAATTTCCCGAAGAAGGATACCACGGAGAAGATATTATTGATACAGCGCGCAATA
TCGTTGCCCGGTTTGGGGACCGTTTTATTCATCTTCCCGAAAAAGAAAGGCAGGAAGCTTTGGGGAAGATTGCTCTGGAA
GAAAAGTTACAGTCCATAAAGAAATCTTTGGAAAATTTCGGGGTAAAGTATGATGTCTGGTTTTCCGAAAGATCGCTCCA
TGAATCCGGCGAAGTAGAAAAAACTGTAAAACTTTTACTGGAGCGGGGTTATTTGTACGAAAAGGATGGAGCTCTCTGGT
TTGCTGCTTCGAAATTAGGCGAAGAAAAAGATGAAGTGCTGGTCAGAAAAAATGGTGTGCCGACGTATTATGCGGCGGAT
ATTGCTTACCACAAAAATAAGTTTGACCGGGGCTTTGATCTGGTAATTAACATCTGGGGGGCTGACCATCACGGCCATGT
AAGCCGGATGAAAACTGCCCTTAAAGCGTTAGGCTATGATCCGGAACGGCTTATTGTTATCTTAATGCAGTTAGTCCGAC
TCTTCCAGGGCGGGGAACTGGTGCGGATGTCCAAAAGAACCGGGCAATACATTACGTTAGATGAGCTGGTGGAAGAAGTG
GGGGTTGATGCTGCGCGCTACTTCTTTGTCATGCGCAGCCACGATGCCCACCTGGATTTTGACCTGGATTTGGCCAAAGA
GAAATCCAACGAAAACCCGGTTTACTATATTCAATATGCCCATGCCCGGATAATGAGTCTTTACCGGCAGTGTAACGAGC
AGGGAGTTACTTTACCTCCGGTGGAGGATGTGGATTTAGCAATTCTAAGTAGTGAGGCGGAATTAAACCTTTTACGCCAT
CTGGCCGAGTTTCCGGTGGAAATAGAAAAATGTGCTACTGCCTTAGCTCCTCATCACCTGGCAAGATACCTCCATGAATT
AGCGGGGTATTTCCACACCTTTTACAATAGCTGCCGGGTTTTAGGGGTAGAGGAAAACTTAAGTAAAGCCCGGTTGCTGT
TAGTTGAAGCAACCCGGATCGTGCTTAGAAAAGGATTAAAAATGCTGGGCGTTTCAGCTCCGGAGAAAATGTAA

Upstream 100 bases:

>100_bases
CAGAAATGGGTGGGACGATTAAGCTTTTATATGAATTAAATTTAGAGCGGCAAAAGGTTTCCGACAACTTTTTGTCCATC
GAGGTCAAGGAGGCTTGAAA

Downstream 100 bases:

>100_bases
CTTTTAGCTTGACTTTGGCTCTTTTGGCCGTATAGAATGGAAAAAGTGATTATTTGGTAGTATTGGGAGGATTAAGATGA
CGAAGTTTATTTTTGTGACC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MEYLLQRITGEIAGSLRRAAVKAGYLDAEDELAFELEKPKEKAHGDLATNLAMLLTKKARKNPREIAATLLEYLEIPAVV
ERVEIAGPGFINFYFKKDWVVAVIPEILSFGEKYGRLAIGAGKRVQVEFVSANPTGLLHMGNGRGAALGDILANILTEAG
YEVSREYYINDAGNQIENFNKSVEARYLELLGYKVEFPEEGYHGEDIIDTARNIVARFGDRFIHLPEKERQEALGKIALE
EKLQSIKKSLENFGVKYDVWFSERSLHESGEVEKTVKLLLERGYLYEKDGALWFAASKLGEEKDEVLVRKNGVPTYYAAD
IAYHKNKFDRGFDLVINIWGADHHGHVSRMKTALKALGYDPERLIVILMQLVRLFQGGELVRMSKRTGQYITLDELVEEV
GVDAARYFFVMRSHDAHLDFDLDLAKEKSNENPVYYIQYAHARIMSLYRQCNEQGVTLPPVEDVDLAILSSEAELNLLRH
LAEFPVEIEKCATALAPHHLARYLHELAGYFHTFYNSCRVLGVEENLSKARLLLVEATRIVLRKGLKMLGVSAPEKM

Sequences:

>Translated_557_residues
MEYLLQRITGEIAGSLRRAAVKAGYLDAEDELAFELEKPKEKAHGDLATNLAMLLTKKARKNPREIAATLLEYLEIPAVV
ERVEIAGPGFINFYFKKDWVVAVIPEILSFGEKYGRLAIGAGKRVQVEFVSANPTGLLHMGNGRGAALGDILANILTEAG
YEVSREYYINDAGNQIENFNKSVEARYLELLGYKVEFPEEGYHGEDIIDTARNIVARFGDRFIHLPEKERQEALGKIALE
EKLQSIKKSLENFGVKYDVWFSERSLHESGEVEKTVKLLLERGYLYEKDGALWFAASKLGEEKDEVLVRKNGVPTYYAAD
IAYHKNKFDRGFDLVINIWGADHHGHVSRMKTALKALGYDPERLIVILMQLVRLFQGGELVRMSKRTGQYITLDELVEEV
GVDAARYFFVMRSHDAHLDFDLDLAKEKSNENPVYYIQYAHARIMSLYRQCNEQGVTLPPVEDVDLAILSSEAELNLLRH
LAEFPVEIEKCATALAPHHLARYLHELAGYFHTFYNSCRVLGVEENLSKARLLLVEATRIVLRKGLKMLGVSAPEKM
>Mature_557_residues
MEYLLQRITGEIAGSLRRAAVKAGYLDAEDELAFELEKPKEKAHGDLATNLAMLLTKKARKNPREIAATLLEYLEIPAVV
ERVEIAGPGFINFYFKKDWVVAVIPEILSFGEKYGRLAIGAGKRVQVEFVSANPTGLLHMGNGRGAALGDILANILTEAG
YEVSREYYINDAGNQIENFNKSVEARYLELLGYKVEFPEEGYHGEDIIDTARNIVARFGDRFIHLPEKERQEALGKIALE
EKLQSIKKSLENFGVKYDVWFSERSLHESGEVEKTVKLLLERGYLYEKDGALWFAASKLGEEKDEVLVRKNGVPTYYAAD
IAYHKNKFDRGFDLVINIWGADHHGHVSRMKTALKALGYDPERLIVILMQLVRLFQGGELVRMSKRTGQYITLDELVEEV
GVDAARYFFVMRSHDAHLDFDLDLAKEKSNENPVYYIQYAHARIMSLYRQCNEQGVTLPPVEDVDLAILSSEAELNLLRH
LAEFPVEIEKCATALAPHHLARYLHELAGYFHTFYNSCRVLGVEENLSKARLLLVEATRIVLRKGLKMLGVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=594, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI197100773, Length=543, Percent_Identity=23.572744014733, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1788184, Length=599, Percent_Identity=25.2086811352254, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320548, Length=567, Percent_Identity=25.9259259259259, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI18859963, Length=563, Percent_Identity=24.5115452930728, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CARHZ (Q3AFT8)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_358996.1
- ProteinModelPortal:   Q3AFT8
- STRING:   Q3AFT8
- GeneID:   3726343
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0124
- NMPDR:   fig|246194.3.peg.812
- TIGR:   CHY_0124
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   CHYD246194:CHY_0124-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63059; Mature: 63059

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLLQRITGEIAGSLRRAAVKAGYLDAEDELAFELEKPKEKAHGDLATNLAMLLTKKAR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHCCHHHHHHHHHHHHHHC
KNPREIAATLLEYLEIPAVVERVEIAGPGFINFYFKKDWVVAVIPEILSFGEKYGRLAIG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCEEEC
AGKRVQVEFVSANPTGLLHMGNGRGAALGDILANILTEAGYEVSREYYINDAGNQIENFN
CCCEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHCCEEEECCCCHHHHHHH
KSVEARYLELLGYKVEFPEEGYHGEDIIDTARNIVARFGDRFIHLPEKERQEALGKIALE
HHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
EKLQSIKKSLENFGVKYDVWFSERSLHESGEVEKTVKLLLERGYLYEKDGALWFAASKLG
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEHHHHC
EEKDEVLVRKNGVPTYYAADIAYHKNKFDRGFDLVINIWGADHHGHVSRMKTALKALGYD
CCHHHEEEECCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
PERLIVILMQLVRLFQGGELVRMSKRTGQYITLDELVEEVGVDAARYFFVMRSHDAHLDF
HHHHHHHHHHHHHHHCCCCEEEEHHCCCCEEEHHHHHHHHCCCHHHHEEEEECCCCCCCC
DLDLAKEKSNENPVYYIQYAHARIMSLYRQCNEQGVTLPPVEDVDLAILSSEAELNLLRH
CCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHH
LAEFPVEIEKCATALAPHHLARYLHELAGYFHTFYNSCRVLGVEENLSKARLLLVEATRI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
VLRKGLKMLGVSAPEKM
HHHCCHHHHCCCCCCCC
>Mature Secondary Structure
MEYLLQRITGEIAGSLRRAAVKAGYLDAEDELAFELEKPKEKAHGDLATNLAMLLTKKAR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCHHHHCCHHHHHHHHHHHHHHC
KNPREIAATLLEYLEIPAVVERVEIAGPGFINFYFKKDWVVAVIPEILSFGEKYGRLAIG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCEEEC
AGKRVQVEFVSANPTGLLHMGNGRGAALGDILANILTEAGYEVSREYYINDAGNQIENFN
CCCEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHCCEEEECCCCHHHHHHH
KSVEARYLELLGYKVEFPEEGYHGEDIIDTARNIVARFGDRFIHLPEKERQEALGKIALE
HHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
EKLQSIKKSLENFGVKYDVWFSERSLHESGEVEKTVKLLLERGYLYEKDGALWFAASKLG
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEHHHHC
EEKDEVLVRKNGVPTYYAADIAYHKNKFDRGFDLVINIWGADHHGHVSRMKTALKALGYD
CCHHHEEEECCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
PERLIVILMQLVRLFQGGELVRMSKRTGQYITLDELVEEVGVDAARYFFVMRSHDAHLDF
HHHHHHHHHHHHHHHCCCCEEEEHHCCCCEEEHHHHHHHHCCCHHHHEEEEECCCCCCCC
DLDLAKEKSNENPVYYIQYAHARIMSLYRQCNEQGVTLPPVEDVDLAILSSEAELNLLRH
CCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHH
LAEFPVEIEKCATALAPHHLARYLHELAGYFHTFYNSCRVLGVEENLSKARLLLVEATRI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
VLRKGLKMLGVSAPEKM
HHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA