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The map label for this gene is hppA

Identifier: 78043894

GI number: 78043894

Start: 252458

End: 254518

Strand: Direct

Name: hppA

Synonym: CHY_0286

Alternate gene names: 78043894

Gene position: 252458-254518 (Clockwise)

Preceding gene: 78044803

Following gene: 78042955

Centisome position: 10.51

GC content: 50.22

Gene sequence:

>2061_bases
ATGGAAAACGGGATGACTTTAGCTTATTACGGCTTGGGAGCGGGGATCTTAGCAATTCTTTTTGCCCTGTATCTTTTTTC
CTCGGTTTTAAAGGAAGATATGGGGAATGAAAAAATGCGGGAGATTTCCCAGGCCATCTTTGAAGGGGCTATGGCGTATT
TAAACCGCCAGTACAAGACGTTAATTCCTTTTGCCCTTGTGGTTTTTGTTTTGCTGGTTGTTGGTTTTGGTTATAAGGAA
GGGGACTTTGGCTACGGACTTAAAGTTGGTGTATCGTTTCTGGTAGGTGCTATTGCCTCGGCTCTTGCCGGTTATGCCGG
GATGACCAGTACCACCAAAGCTAATGCCCGGACGACCCAGGCTGCGCGGAAAAGCTTGAACGCTGCCTTAAACGTAGCCT
TCAGAGCCGGTGGCGTCATGGGGATGTCCGTTGCCGGGCTTGGTTTACTTGGTGTTTCGGCCTTATATATTATTTTTAAA
GATGTTCATGTTATCGATAGCTTTGCCTTTGGGGCTTCGGCCATTGCTTTCTTTGCCCGGGTTGGCGGTGGTATTTATAC
CAAAGCCGCTGACGTTGGTGCCGACCTGGTGGGTAAAGTTGAAGCGGGTATTCCCGAAGACGATCCCAGAAACCCGGCGG
TTATTGCGGACAACGTGGGGGACAACGTTGGCGATACTGCCGGTATGGGTGCCGACTTGTTTGAATCTTACGGCGCTACC
ACCATGGCAGCTATGCTCTTAGGCCTTACCTTTGCCAAGAACCACGGCTTTAGTGAAGTTTTAGGTGCAACTTTCCCGTT
GCTTCTCGGGGCGGCGGGGATTGTAGCGGCAATTATCAGTACTTTCTTTGTGCGGACTTCCGAAGATGGAAATCCCCAAA
TGGCTTTAAATATTGGTTTGTGGTCTACCAACTTTATTACGGCAATCTTTACCTACATTATAGCCCAGTACGTATTTGGC
AGTGAGTGGGCTCCGAAAATCTTTATCGCGGTAGTTTCCGGTTTAGTGGTTAACGTGGCAATTGGCTCCTTAACCGAATA
CTATACCTCCAACTTAAAGCCTCCGGCTCAAAAAATTGCTGAGGCTTCCACCACCGGTCCGGCAACTAACATCATTTCCG
GGATTGCGGTTGGTATGCGGAGTACGTACTTACCCATTATCGTAATTGTAGCGGCTATTATGGTGGGCTACTGGGCTGCA
GGCTTTTACGGAATTGCTCTGGCGGCCATGGGAATGCTGGCTACTGCCGCTATGGTTGTGGCGGTGGACTCCTTTGGTCC
GGTGGCCGACAACGCCGGTGGTATTGCAGAAATGGCGGAACTTGGTCCGGAAATCCGGAATAAAACCGACAAGCTCGATG
CCGTTGGTAACACCACTGCAGCGGTAGCTAAAGGGTTTGCCATTGGTTCTGCGGCTTTAACTGCCCTTGCTTTATTCTCT
GCTTATACCGACCTGGCCAAAACTAACCCCAACTTGCAAAAGTACCTGGTAAACGGCAAGTTTGACTTAAATATTACCGA
TCCATGGGTCTTAGTGGGTCTCTTCCTGGGTGGTACCGTGGCCTTTTTAGTAGCGGCTCTAACTATGGAGTCGGTAGGAA
AAGCGGCTTTTGACATGATTGAAGAGGTACGGCGCCAGTTTAGAGAGATTCCCGGTCTCATGGAAGGAAAAGCCCGGCCC
GATTATGCCCGCTGTGTTTCCATCAGTACGGCAGCGGCGATCCGGCAGATGATTGCACCGGGCTTACTGGCGGTTGGTGC
TCCTCTGGCTATTGGCTTTATCCTTGGCTTTAAAGCATTGACCGGTTATTTAGCCGGCGTTACCGCAACCGGAGTGCTTT
TAGCCATTTATATGGCCAATGCTGGCGGTGCCTGGGATAACGCGAAAAAATATATAGAAGCGGGAAATCTTGGCGGAAAA
GGTAGCGATACGCACAAAGCAGCGGTAGTGGGCGATACCGTTGGCGACCCCTTCAAAGATACTTCTGGCCCTGCGATGAA
CCCGCTGATGAAAGTGGCCGGAACCTTTGCGCTGATCATTGTGCCCCTGTTGCTATTCTAA

Upstream 100 bases:

>100_bases
GACGGTAGTTGCGGTAATTTTATTTATGATTTTGTCGTTGGTGCTGGCTTTACTTTTTTAAAGATAAATAATTTATTTTA
AAAATTGAGGAGGGTGAGAA

Downstream 100 bases:

>100_bases
AAGAATCTAACGGAGCAGCCCTAATAAGTAGGGCTGCTTTTTTATTACCTTTCCCAATCTTGCCGCGGAAGAAATTACCT
GCTAAAATGAGACCAGAAAG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKTLIPFALVVFVLLVVGFGYKE
GDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQAARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFK
DVHVIDSFAFGASAIAFFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGAT
TMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGLWSTNFITAIFTYIIAQYVFG
SEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIAEASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAA
GFYGIALAAMGMLATAAMVVAVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFS
AYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMIEEVRRQFREIPGLMEGKARP
DYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKALTGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGK
GSDTHKAAVVGDTVGDPFKDTSGPAMNPLMKVAGTFALIIVPLLLF

Sequences:

>Translated_686_residues
MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKTLIPFALVVFVLLVVGFGYKE
GDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQAARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFK
DVHVIDSFAFGASAIAFFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGAT
TMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGLWSTNFITAIFTYIIAQYVFG
SEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIAEASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAA
GFYGIALAAMGMLATAAMVVAVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFS
AYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMIEEVRRQFREIPGLMEGKARP
DYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKALTGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGK
GSDTHKAAVVGDTVGDPFKDTSGPAMNPLMKVAGTFALIIVPLLLF
>Mature_686_residues
MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKTLIPFALVVFVLLVVGFGYKE
GDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQAARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFK
DVHVIDSFAFGASAIAFFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGAT
TMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGLWSTNFITAIFTYIIAQYVFG
SEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIAEASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAA
GFYGIALAAMGMLATAAMVVAVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFS
AYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMIEEVRRQFREIPGLMEGKARP
DYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKALTGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGK
GSDTHKAAVVGDTVGDPFKDTSGPAMNPLMKVAGTFALIIVPLLLF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPPA_CARHZ (Q3AFC6)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359158.1
- STRING:   Q3AFC6
- GeneID:   3726517
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0286
- NMPDR:   fig|246194.3.peg.335
- TIGR:   CHY_0286
- eggNOG:   COG3808
- HOGENOM:   HBG593668
- OMA:   AYLARQY
- ProtClustDB:   PRK00733
- BioCyc:   CHYD246194:CHY_0286-MONOMER
- HAMAP:   MF_01129
- InterPro:   IPR004131
- PIRSF:   PIRSF001265
- TIGRFAMs:   TIGR01104

Pfam domain/function: PF03030 H_PPase

EC number: =3.6.1.1

Molecular weight: Translated: 71064; Mature: 71064

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe1b6a88)-; HASH(0x951ff04)-; HASH(0xff84bdc)-; HASH(0xf57504c)-; HASH(0xfa58cf0)-; HASH(0xfcd517c)-; HASH(0x106d7078)-; HASH(0xfae8f90)-; HASH(0x101836ec)-; HASH(0x109d94ec)-; HASH(0x1068acf0)-; HASH(0x1045dbf4)-; HASH(0x1053dbe8)-; HASH(0x1087b6ec)-; HASH(0x104b8f30)-; HASH(0x953a4e0)-;

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIPFALVVFVLLVVGFGYKEGDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFKDVHVIDSFAFGASAIAFFAR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGAT
HCCCCEEHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCHH
TMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
WSTNFITAIFTYIIAQYVFGSEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIA
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAAGFYGIALAAMGMLATAAMVV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFS
HHHCCCCCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMI
HHHHHHHCCCCHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEVRRQFREIPGLMEGKARPDYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKAL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGKGSDTHKAAVVGDTVGDPFKD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
TSGPAMNPLMKVAGTFALIIVPLLLF
CCCCHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LIPFALVVFVLLVVGFGYKEGDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFKDVHVIDSFAFGASAIAFFAR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGAT
HCCCCEEHHHHHCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHCCHH
TMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
WSTNFITAIFTYIIAQYVFGSEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIA
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAAGFYGIALAAMGMLATAAMVV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFS
HHHCCCCCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMI
HHHHHHHCCCCHHHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEVRRQFREIPGLMEGKARPDYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKAL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGKGSDTHKAAVVGDTVGDPFKD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
TSGPAMNPLMKVAGTFALIIVPLLLF
CCCCHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA