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The map label for this gene is galE [H]

Identifier: 78043738

GI number: 78043738

Start: 473497

End: 474480

Strand: Direct

Name: galE [H]

Synonym: CHY_0545

Alternate gene names: 78043738

Gene position: 473497-474480 (Clockwise)

Preceding gene: 78042966

Following gene: 78043430

Centisome position: 19.72

GC content: 42.17

Gene sequence:

>984_bases
ATGATTTTAGTTACCGGTGGAGCTGGTTATATTGGTTCTCACATAGTTCGGCAGTTATGCCTAAAAAATGAAAAAGTTTT
GGTAGTGGATAATCTTTCTAAAGGGCATAAGAAAGCTGTGGATACAAGGGCTAAGCTTATTGTGGGCGATTTCGGGGATG
AAAACCTCCTTCTGGAAATTTTCAAGAAATATGATATAAAAGCGGTTATTCACATGGCGGCGCAAAGTTTAGTGGGGGAA
TCAATGAGCCAGCCGGAAAAATATTTTGAGGAAAATATCAGTAAAACCCTGAGTTTGTTAAAAGTAATGCTCAAAGCTAA
TGTTAAGAAAATGGTGTTTTCCAGTACTGCAGCGGTTTACGGAGAACCGGAAAAATGGCCGATAACCGAAGATTTTCCGC
AAAAACCAACCAATGTTTACGGTTATTCCAAACTGGTAATTGAGCAGTGCCTTGAGTGGTATCGCCAAATACATGGTTTT
AATTACGTATCTTTACGGTATTTTAATGCTGCCGGGGCAGACCCTTCCGGGGATATTGGGGAAGACCACAATCCGGAAAC
CCACTTAATTCCCCTGATTTTCAAAGTAATTTTAGGAGAACAGGAAGAGTTGACGGTTTTTGGGACCGATTATCCCACCC
CGGATGGCACTTGTATCCGGGATTATATTCACGTAAACGACCTTGCCGAGGCCCATATTCTGGCTTTAAATAAACTCAAT
AAAGACGAAAGCGGCGTTTACAATCTCGGGAACCAAAAAGGTTTTTCCGTAAAAGAAATAATTAAGGTCGCAGAAGAAGT
TACCGGGGTAAAAGTTAAAGTTCGTTACGGCCAGCGTCGTCCCGGAGATCCGGCGGTTTTGGTGGCTTCTTCGGAAAAAA
TTCAGAAAGAACTCAATTTTACTCCCAAATTTGGAGACATTAAAACTATCGTCCAAACTGCCTGGGAGTGGCACAAAAAC
AATCCCCGGGGGTATGACCGGTAA

Upstream 100 bases:

>100_bases
ATGAAATTATCCTGGTAGGAACCAAGAAAGTTCCAAACTCTTCTGCAAAGGAAAGTTCAGTAACGGAAAATGTTTATTAA
TATTTAGAGGAGAGGATTGG

Downstream 100 bases:

>100_bases
ATGTCCAAGAAAATAGTATTAAAAGCCACCCTTTTAATAATGGCTTTAACATTAACCAGCAGGATTCTGGGTTTTGTCCG
GGAGATGGCCATTGCTTCCG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MILVTGGAGYIGSHIVRQLCLKNEKVLVVDNLSKGHKKAVDTRAKLIVGDFGDENLLLEIFKKYDIKAVIHMAAQSLVGE
SMSQPEKYFEENISKTLSLLKVMLKANVKKMVFSSTAAVYGEPEKWPITEDFPQKPTNVYGYSKLVIEQCLEWYRQIHGF
NYVSLRYFNAAGADPSGDIGEDHNPETHLIPLIFKVILGEQEELTVFGTDYPTPDGTCIRDYIHVNDLAEAHILALNKLN
KDESGVYNLGNQKGFSVKEIIKVAEEVTGVKVKVRYGQRRPGDPAVLVASSEKIQKELNFTPKFGDIKTIVQTAWEWHKN
NPRGYDR

Sequences:

>Translated_327_residues
MILVTGGAGYIGSHIVRQLCLKNEKVLVVDNLSKGHKKAVDTRAKLIVGDFGDENLLLEIFKKYDIKAVIHMAAQSLVGE
SMSQPEKYFEENISKTLSLLKVMLKANVKKMVFSSTAAVYGEPEKWPITEDFPQKPTNVYGYSKLVIEQCLEWYRQIHGF
NYVSLRYFNAAGADPSGDIGEDHNPETHLIPLIFKVILGEQEELTVFGTDYPTPDGTCIRDYIHVNDLAEAHILALNKLN
KDESGVYNLGNQKGFSVKEIIKVAEEVTGVKVKVRYGQRRPGDPAVLVASSEKIQKELNFTPKFGDIKTIVQTAWEWHKN
NPRGYDR
>Mature_327_residues
MILVTGGAGYIGSHIVRQLCLKNEKVLVVDNLSKGHKKAVDTRAKLIVGDFGDENLLLEIFKKYDIKAVIHMAAQSLVGE
SMSQPEKYFEENISKTLSLLKVMLKANVKKMVFSSTAAVYGEPEKWPITEDFPQKPTNVYGYSKLVIEQCLEWYRQIHGF
NYVSLRYFNAAGADPSGDIGEDHNPETHLIPLIFKVILGEQEELTVFGTDYPTPDGTCIRDYIHVNDLAEAHILALNKLN
KDESGVYNLGNQKGFSVKEIIKVAEEVTGVKVKVRYGQRRPGDPAVLVASSEKIQKELNFTPKFGDIKTIVQTAWEWHKN
NPRGYDR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=40.6432748538012, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=40.6432748538012, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=40.6432748538012, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=28.2738095238095, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI42516563, Length=299, Percent_Identity=27.7591973244147, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4507709, Length=338, Percent_Identity=23.6686390532544, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=39.7014925373134, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1788353, Length=359, Percent_Identity=27.5766016713092, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790049, Length=270, Percent_Identity=31.1111111111111, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=351, Percent_Identity=37.037037037037, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=353, Percent_Identity=36.5439093484419, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17568069, Length=278, Percent_Identity=28.4172661870504, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=24.5398773006135, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17554428, Length=339, Percent_Identity=24.188790560472, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=347, Percent_Identity=39.4812680115274, Blast_Score=216, Evalue=3e-57,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=40.2332361516035, Blast_Score=228, Evalue=4e-60,
Organism=Drosophila melanogaster, GI21356223, Length=340, Percent_Identity=25.2941176470588, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36775; Mature: 36775

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGAGYIGSHIVRQLCLKNEKVLVVDNLSKGHKKAVDTRAKLIVGDFGDENLLLEI
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHEEEEECCCCCHHHHHH
FKKYDIKAVIHMAAQSLVGESMSQPEKYFEENISKTLSLLKVMLKANVKKMVFSSTAAVY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GEPEKWPITEDFPQKPTNVYGYSKLVIEQCLEWYRQIHGFNYVSLRYFNAAGADPSGDIG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
EDHNPETHLIPLIFKVILGEQEELTVFGTDYPTPDGTCIRDYIHVNDLAEAHILALNKLN
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
KDESGVYNLGNQKGFSVKEIIKVAEEVTGVKVKVRYGQRRPGDPAVLVASSEKIQKELNF
CCCCCCEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECHHHHHHHCCC
TPKFGDIKTIVQTAWEWHKNNPRGYDR
CCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MILVTGGAGYIGSHIVRQLCLKNEKVLVVDNLSKGHKKAVDTRAKLIVGDFGDENLLLEI
CEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHEEEEECCCCCHHHHHH
FKKYDIKAVIHMAAQSLVGESMSQPEKYFEENISKTLSLLKVMLKANVKKMVFSSTAAVY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
GEPEKWPITEDFPQKPTNVYGYSKLVIEQCLEWYRQIHGFNYVSLRYFNAAGADPSGDIG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
EDHNPETHLIPLIFKVILGEQEELTVFGTDYPTPDGTCIRDYIHVNDLAEAHILALNKLN
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
KDESGVYNLGNQKGFSVKEIIKVAEEVTGVKVKVRYGQRRPGDPAVLVASSEKIQKELNF
CCCCCCEECCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECHHHHHHHCCC
TPKFGDIKTIVQTAWEWHKNNPRGYDR
CCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]