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The map label for this gene is allR [H]

Identifier: 78043639

GI number: 78043639

Start: 1562638

End: 1563423

Strand: Direct

Name: allR [H]

Synonym: CHY_1745

Alternate gene names: 78043639

Gene position: 1562638-1563423 (Clockwise)

Preceding gene: 78043996

Following gene: 78043946

Centisome position: 65.07

GC content: 41.73

Gene sequence:

>786_bases
ATGGTTTTAGAAGAAAAAGAAAATAAATCGGGAGCCCCGGCCGTGGAAATGGCTATCAAAATCTTAACTTATTTAAGTAG
ATACCGGAATAAAAACCGCACCCTTGCCGAAATTGCCCGGGACTTAAATATCAATAAAAGTTCCTGCCACCGGATATTGA
AAGTTCTTCTGGATTACCGGCTGGTATCCTATGACAAAAACACCAGGCAGTTCAGCCTGGGATCTTTTTTAATTGTTTTA
GGTAGCCGGGCTTCCGAATTCAACGACTACTTAAAAATTGCCAAACAGCATTTAAAAGAATTAGCAGAAACCACCAAACA
AACCTGTGTCCTTGTAGAGCCAATCGCCAACAACCGCCTAGTTTACATTGCCAAAGAAGAGCCGGAGGCAGCAGTACGGA
TTACCGTCAGTATCGGTCAATCGTTTCCGGTAACCAGTGCTTCCTTTGGAAAATGTTATCTGGCCTTCCTTCCAGAAAAG
GAAGCCAGGGAAATTGTAAAAGAGGTAGGAATCAAGCAATTTACCGACAAAAGTATTACCAATGTAGAGGAATTTTTTCA
AAGTTTGGAGGTAATTCGAAAGCAGGGCTATGCGGTGAGCTTTGAAGAACACACTCCGGGGGTTTTTGGCATTAGCGCTC
CTGTTTTTGATAACAGCGGAAGTGTTCGCATGGTTGTATCGTGTATTGGGCTTGCTTCTTCAGTGAATGAAGAAACAATT
AATTTTTACGCTGACAAAGTTAAAACTACCGCGCAAAAAATCACCGCTATTTTTTCCGATATGTAA

Upstream 100 bases:

>100_bases
TAAATTTTTATGTCAATAATTTTGCAATAAATTTTAAAATTTTCTTACAATTTTTCTTAAACCGCTTGCAGTGTTATGAT
AAATTAGGAGAGGTGACGTT

Downstream 100 bases:

>100_bases
CAACACCCCGAAGTTAAACCTCCGGGGTGTTTTCCTTTTAACCACCGCTTAAGTAGGGAAAGACAAATACTTCATCCCCA
TCTTTTAGCAGCTGGTTGTC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVLEEKENKSGAPAVEMAIKILTYLSRYRNKNRTLAEIARDLNINKSSCHRILKVLLDYRLVSYDKNTRQFSLGSFLIVL
GSRASEFNDYLKIAKQHLKELAETTKQTCVLVEPIANNRLVYIAKEEPEAAVRITVSIGQSFPVTSASFGKCYLAFLPEK
EAREIVKEVGIKQFTDKSITNVEEFFQSLEVIRKQGYAVSFEEHTPGVFGISAPVFDNSGSVRMVVSCIGLASSVNEETI
NFYADKVKTTAQKITAIFSDM

Sequences:

>Translated_261_residues
MVLEEKENKSGAPAVEMAIKILTYLSRYRNKNRTLAEIARDLNINKSSCHRILKVLLDYRLVSYDKNTRQFSLGSFLIVL
GSRASEFNDYLKIAKQHLKELAETTKQTCVLVEPIANNRLVYIAKEEPEAAVRITVSIGQSFPVTSASFGKCYLAFLPEK
EAREIVKEVGIKQFTDKSITNVEEFFQSLEVIRKQGYAVSFEEHTPGVFGISAPVFDNSGSVRMVVSCIGLASSVNEETI
NFYADKVKTTAQKITAIFSDM
>Mature_261_residues
MVLEEKENKSGAPAVEMAIKILTYLSRYRNKNRTLAEIARDLNINKSSCHRILKVLLDYRLVSYDKNTRQFSLGSFLIVL
GSRASEFNDYLKIAKQHLKELAETTKQTCVLVEPIANNRLVYIAKEEPEAAVRITVSIGQSFPVTSASFGKCYLAFLPEK
EAREIVKEVGIKQFTDKSITNVEEFFQSLEVIRKQGYAVSFEEHTPGVFGISAPVFDNSGSVRMVVSCIGLASSVNEETI
NFYADKVKTTAQKITAIFSDM

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788131, Length=222, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788581, Length=250, Percent_Identity=28.8, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789999, Length=259, Percent_Identity=28.957528957529, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786468, Length=231, Percent_Identity=29.004329004329, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082359, Length=245, Percent_Identity=21.6326530612245, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790752, Length=250, Percent_Identity=24.4, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29256; Mature: 29256

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLEEKENKSGAPAVEMAIKILTYLSRYRNKNRTLAEIARDLNINKSSCHRILKVLLDYR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVSYDKNTRQFSLGSFLIVLGSRASEFNDYLKIAKQHLKELAETTKQTCVLVEPIANNRL
HHHCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEE
VYIAKEEPEAAVRITVSIGQSFPVTSASFGKCYLAFLPEKEAREIVKEVGIKQFTDKSIT
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHCCHHHH
NVEEFFQSLEVIRKQGYAVSFEEHTPGVFGISAPVFDNSGSVRMVVSCIGLASSVNEETI
HHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHH
NFYADKVKTTAQKITAIFSDM
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLEEKENKSGAPAVEMAIKILTYLSRYRNKNRTLAEIARDLNINKSSCHRILKVLLDYR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LVSYDKNTRQFSLGSFLIVLGSRASEFNDYLKIAKQHLKELAETTKQTCVLVEPIANNRL
HHHCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEE
VYIAKEEPEAAVRITVSIGQSFPVTSASFGKCYLAFLPEKEAREIVKEVGIKQFTDKSIT
EEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHCCHHHH
NVEEFFQSLEVIRKQGYAVSFEEHTPGVFGISAPVFDNSGSVRMVVSCIGLASSVNEETI
HHHHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHH
NFYADKVKTTAQKITAIFSDM
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA