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The map label for this gene is fadD [C]

Identifier: 78043188

GI number: 78043188

Start: 587832

End: 588101

Strand: Direct

Name: fadD [C]

Synonym: CHY_0673

Alternate gene names: 78043188

Gene position: 587832-588101 (Clockwise)

Preceding gene: 78044698

Following gene: 78044999

Centisome position: 24.48

GC content: 37.41

Gene sequence:

>270_bases
ATGACTCCTCGGGAAATCGAAGATGTTTTTTACGAAAGTCCGGAAGTTTTAGATGTGGCTGTAGTAGGGATAAATGAGCC
TTTAGCTACCGAAAATGCTGTGGCTTTTGTGGTGTTAAAAGATAAAGCTAAAATTGAAACTTTGTTTGAGCTGTGTAAAA
CAAAACTTCCCCCCCGGTATATCCCCAAAAAAATTATTCCGGTAGATTTTATTCCCAAGACCAAAACCGGAAAGGTAATT
TTTAGCGAACTAAAAGAAATGGCATTATGA

Upstream 100 bases:

>100_bases
TTTTTGGCGTTTTAACGTTAAATTCATGCCACTTAAAGTTTTGTCATTCCGTAACCTCCAATTACATGTGTAAAATAATG
TAAGAAAAGGAGGGAGCGGG

Downstream 100 bases:

>100_bases
AAAAACGCGGCTTTTAGCCGCGTTTTTTATCTTACCCTGACCGCACCAGCATAACAGCTGGCATAATAACCTTCCCTTAA
GGAGGAGATAATTACCCGGT

Product: putative long-chain-fatty-acid--CoA ligase, truncation

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Fatty-Acid-CoA Ligase

Number of amino acids: Translated: 89; Mature: 88

Protein sequence:

>89_residues
MTPREIEDVFYESPEVLDVAVVGINEPLATENAVAFVVLKDKAKIETLFELCKTKLPPRYIPKKIIPVDFIPKTKTGKVI
FSELKEMAL

Sequences:

>Translated_89_residues
MTPREIEDVFYESPEVLDVAVVGINEPLATENAVAFVVLKDKAKIETLFELCKTKLPPRYIPKKIIPVDFIPKTKTGKVI
FSELKEMAL
>Mature_88_residues
TPREIEDVFYESPEVLDVAVVGINEPLATENAVAFVVLKDKAKIETLFELCKTKLPPRYIPKKIIPVDFIPKTKTGKVIF
SELKEMAL

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 10048; Mature: 9917

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPREIEDVFYESPEVLDVAVVGINEPLATENAVAFVVLKDKAKIETLFELCKTKLPPRY
CCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
IPKKIIPVDFIPKTKTGKVIFSELKEMAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TPREIEDVFYESPEVLDVAVVGINEPLATENAVAFVVLKDKAKIETLFELCKTKLPPRY
CCHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
IPKKIIPVDFIPKTKTGKVIFSELKEMAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA