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The map label for this gene is cat1 [H]

Identifier: 78043112

GI number: 78043112

Start: 1181138

End: 1182442

Strand: Direct

Name: cat1 [H]

Synonym: CHY_1324

Alternate gene names: 78043112

Gene position: 1181138-1182442 (Clockwise)

Preceding gene: 78042819

Following gene: 78045023

Centisome position: 49.18

GC content: 37.32

Gene sequence:

>1305_bases
ATGTTATTAAACTATCATGCCGAATATAGAAAAAAATTAACAACTGTTGAGCAAGCACTGGAAGTAATTACGAATAATTG
TAATGTATTTGTATCCCTTGGTGCAGCAGAACCATTAATGCTCTTGGACGGTTTGGGAAAAAGAGTTTTAGAGCAAGATT
TAAGAGGTATTAAAGTCTTTCAACTCCTTCCAGTACAAGATTCTTTGTACTTAAAACCAGAGTTAAGTGAGCGCATAATG
CATATATCGATGTTTGCCGGAAGGCCGGTGCGCGAATTAATAAATCAGGGTTTTGCTGAGATGATTCCTTGTCATTTCCA
CGATGTTCCCCAAATTATTCAGGATTATTTAGATGTCGATGTTTTTATGACAACGGTTTCGCCCATGGATGAACATGGCT
TTTTTAGCCTGGGAACATCGGTGGATTATTCGCTTGCAGCCTTAAAGAAGGCCAAAAAGGTAATATTAGAAATTAACCCC
AATATGCCAAGAACCTTTGGCCAGGGAATTGTTCATATATCGGAGGTAGATTTTTTGATTGAAAGTGAAAGGCCGCTGCC
TGAGCTTTTTCCAGAAGAACTAAAAGCCGAAGACTTACGCATTGGTGAATATATTGCTGAATTGGTCGAGAATGAGTCAA
CGTTACAATTGGGAATTGGAGGAATACCTAACGCTGTAGCTAAATTTTTAAAGGAAAAGAAAAACTTAGGAATCCATACC
GAAATGATTACCGATAGTATGGTGGATTTAGTAGAAGCTGGAGTAATTACCGGCAGCGCGAAATCCTTGCATCCTTATAA
AATTGTTGGTACATTTGCCTTAGGCACGAAAAAACTTTATAGCTTTTTGAATAACAATCCAATGGTTGAAATGCATCCAG
TTTCTTATACCAACAATCCGTGTGTAATAGCTCAGAATAAAAAGATGATTTCCATCAATACCACTTTGGAAATCGATTTA
TGGGGGCAATGTGCATCCGAAAGTATTGGTACAAAAATTTACAGCGGTACTGGTGGACAAGCCGATTTTGCCCAGGGTGT
TTTACATTCCCCGGGCGGTAAAGGGATAATTGCTTTATACTCTACGGCAAAAAATGGACAGATTTCAAAAATTGTTCCAA
CATTAAAACCTGGGGCAATTGTAACAACTTCTAAAAATGATGTTGATTACATTGTTACCGAATACGGTGTAGCTAAACTT
CGAGGAAAAACTTATCGGGAAAGAGCAAAAGCTTTAATAAATATTGCCCACCCTGATTTTAGAGATGAGTTAAAGTTTCA
AGCCAAAAAGTTAAATATTTTATAA

Upstream 100 bases:

>100_bases
CTAAAATCACCGAAATTTATGAAGGTACCAGTGAAGTGCAAAGAATGGTGATTTCATCGTATATCCTCAAGGAATTTTAG
TGCTTTAAAGGGTGAGGTAA

Downstream 100 bases:

>100_bases
AAACATGAGGAGGGAGATTAGGTGAAACTGGTAGTCCTTTTAAAGCAAACCTTTGACACCGAAGCCAAGATAGTATTAAA
GGACGGGAAAATTGACGACA

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLLNYHAEYRKKLTTVEQALEVITNNCNVFVSLGAAEPLMLLDGLGKRVLEQDLRGIKVFQLLPVQDSLYLKPELSERIM
HISMFAGRPVRELINQGFAEMIPCHFHDVPQIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVILEINP
NMPRTFGQGIVHISEVDFLIESERPLPELFPEELKAEDLRIGEYIAELVENESTLQLGIGGIPNAVAKFLKEKKNLGIHT
EMITDSMVDLVEAGVITGSAKSLHPYKIVGTFALGTKKLYSFLNNNPMVEMHPVSYTNNPCVIAQNKKMISINTTLEIDL
WGQCASESIGTKIYSGTGGQADFAQGVLHSPGGKGIIALYSTAKNGQISKIVPTLKPGAIVTTSKNDVDYIVTEYGVAKL
RGKTYRERAKALINIAHPDFRDELKFQAKKLNIL

Sequences:

>Translated_434_residues
MLLNYHAEYRKKLTTVEQALEVITNNCNVFVSLGAAEPLMLLDGLGKRVLEQDLRGIKVFQLLPVQDSLYLKPELSERIM
HISMFAGRPVRELINQGFAEMIPCHFHDVPQIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVILEINP
NMPRTFGQGIVHISEVDFLIESERPLPELFPEELKAEDLRIGEYIAELVENESTLQLGIGGIPNAVAKFLKEKKNLGIHT
EMITDSMVDLVEAGVITGSAKSLHPYKIVGTFALGTKKLYSFLNNNPMVEMHPVSYTNNPCVIAQNKKMISINTTLEIDL
WGQCASESIGTKIYSGTGGQADFAQGVLHSPGGKGIIALYSTAKNGQISKIVPTLKPGAIVTTSKNDVDYIVTEYGVAKL
RGKTYRERAKALINIAHPDFRDELKFQAKKLNIL
>Mature_434_residues
MLLNYHAEYRKKLTTVEQALEVITNNCNVFVSLGAAEPLMLLDGLGKRVLEQDLRGIKVFQLLPVQDSLYLKPELSERIM
HISMFAGRPVRELINQGFAEMIPCHFHDVPQIIQDYLDVDVFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVILEINP
NMPRTFGQGIVHISEVDFLIESERPLPELFPEELKAEDLRIGEYIAELVENESTLQLGIGGIPNAVAKFLKEKKNLGIHT
EMITDSMVDLVEAGVITGSAKSLHPYKIVGTFALGTKKLYSFLNNNPMVEMHPVSYTNNPCVIAQNKKMISINTTLEIDL
WGQCASESIGTKIYSGTGGQADFAQGVLHSPGGKGIIALYSTAKNGQISKIVPTLKPGAIVTTSKNDVDYIVTEYGVAKL
RGKTYRERAKALINIAHPDFRDELKFQAKKLNIL

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=386, Percent_Identity=26.1658031088083, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563853, Length=420, Percent_Identity=41.4285714285714, Blast_Score=314, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI17538151, Length=433, Percent_Identity=39.4919168591224, Blast_Score=303, Evalue=9e-83,
Organism=Saccharomyces cerevisiae, GI6319456, Length=507, Percent_Identity=25.0493096646943, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21358615, Length=416, Percent_Identity=42.0673076923077, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48094; Mature: 48094

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNYHAEYRKKLTTVEQALEVITNNCNVFVSLGAAEPLMLLDGLGKRVLEQDLRGIKVF
CEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
QLLPVQDSLYLKPELSERIMHISMFAGRPVRELINQGFAEMIPCHFHDVPQIIQDYLDVD
EEECCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHH
VFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVILEINPNMPRTFGQGIVHISEVDFLI
HEEEECCCCCCCCCEEECCCCCHHHHHHHHHCEEEEEECCCCCHHHHCCEEEEEEEEEEE
ESERPLPELFPEELKAEDLRIGEYIAELVENESTLQLGIGGIPNAVAKFLKEKKNLGIHT
ECCCCCHHHCHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEH
EMITDSMVDLVEAGVITGSAKSLHPYKIVGTFALGTKKLYSFLNNNPMVEMHPVSYTNNP
HHHHHHHHHHHHHCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCC
CVIAQNKKMISINTTLEIDLWGQCASESIGTKIYSGTGGQADFAQGVLHSPGGKGIIALY
EEEECCCEEEEEEEEEEEEECCCHHCHHHCCEEECCCCCCCHHHHHHHCCCCCCEEEEEE
STAKNGQISKIVPTLKPGAIVTTSKNDVDYIVTEYGVAKLRGKTYRERAKALINIAHPDF
ECCCCCCHHEECCCCCCCEEEEECCCCCCEEEECCCHHHHCCHHHHHHHHHHEECCCCCH
RDELKFQAKKLNIL
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLLNYHAEYRKKLTTVEQALEVITNNCNVFVSLGAAEPLMLLDGLGKRVLEQDLRGIKVF
CEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
QLLPVQDSLYLKPELSERIMHISMFAGRPVRELINQGFAEMIPCHFHDVPQIIQDYLDVD
EEECCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHH
VFMTTVSPMDEHGFFSLGTSVDYSLAALKKAKKVILEINPNMPRTFGQGIVHISEVDFLI
HEEEECCCCCCCCCEEECCCCCHHHHHHHHHCEEEEEECCCCCHHHHCCEEEEEEEEEEE
ESERPLPELFPEELKAEDLRIGEYIAELVENESTLQLGIGGIPNAVAKFLKEKKNLGIHT
ECCCCCHHHCHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEH
EMITDSMVDLVEAGVITGSAKSLHPYKIVGTFALGTKKLYSFLNNNPMVEMHPVSYTNNP
HHHHHHHHHHHHHCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCC
CVIAQNKKMISINTTLEIDLWGQCASESIGTKIYSGTGGQADFAQGVLHSPGGKGIIALY
EEEECCCEEEEEEEEEEEEECCCHHCHHHCCEEECCCCCCCHHHHHHHCCCCCCEEEEEE
STAKNGQISKIVPTLKPGAIVTTSKNDVDYIVTEYGVAKLRGKTYRERAKALINIAHPDF
ECCCCCCHHEECCCCCCCEEEEECCCCCCEEEECCCHHHHCCHHHHHHHHHHEECCCCCH
RDELKFQAKKLNIL
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]