Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 78043046

GI number: 78043046

Start: 1160849

End: 1162126

Strand: Direct

Name: siaT [H]

Synonym: CHY_1303

Alternate gene names: 78043046

Gene position: 1160849-1162126 (Clockwise)

Preceding gene: 78043624

Following gene: 78044248

Centisome position: 48.34

GC content: 36.7

Gene sequence:

>1278_bases
ATGGCAAATATCTTGTTTACATTATTTATAATATTTGTGGTTTTGAATGTTCCAATAGGTATTGCAATTGGATTGTCAAC
ATTTGGAGCAATATTAGCATCCCAAAAAGTACCATTATTTTTAGTTGCGCAAAGATTATTTACAGGTCTTGATTCTTTCC
CACTTTTGGCAATTCCCCTGTTTATGATTGCTGGAAGTCTAATGGAATCGGGTGGTATTTCCAAACGTTTGATTAATTTT
GCTTCAAATATTGTAGGACCTATACCTGGCGGTTTGGCTATGGTCACCGTACTTGCCTGTATGTTTTTTGCAGCAATTTC
TGGATCTGCGCCAGCTACTGTAGTTGCCATTGGATCAATTATGGTACCGGCTATGATTGAAGCTGGTTATGACAAAGATT
TTGCTGTGGGATTAATAGCAGCATCAGGAATGATAGGTGTCTTAATTCCTCCGAGTATTCCCTTTGTTACCTATGGTATT
ACTATGAATGCTTCAATTGGTAAGCTATTTTTAGCTGGAATAGTGCCCGGTGTTTTATTTGGTCTATCTTTTATGATTAT
TTCCTACTTTTATGCCAAAAAGCGAGGTTATAAAGGGACAGCTAAGCCTACTTGGAAAAGTTTTCTAACTTCATTTAAAG
AAGCAATTTGGGCTTTAGGAATGCCTGCAATTATTTTAGGTGGAATTTACGGTGGGGTATTTACTCCAACTGAAGCAGCG
GCAGTTGCCTGTGTTTATTCTTTAATTGTTGGCTTTTTTATCTACCGGGAACTTACTTTACAAAACATGTTTAAAAGTTT
TGCCAATGCCGGTGTTTCTTCCGCAATGGTTGGTTTAATTATTGCTGCTGCTACCGCAATGGGTTGGGTTTTAACTACGG
AGCAGGTACCAACCAATGTAGCTACAGCTATCTCCAGTATTGCTCACAGTAAATTTATGCTGCTACTGTTAATTAACTTA
ATCTTACTTATTACAGGATGTTTGATGGAACTCAATGCGGCAATCATTATTTTGGGGCCAATTTTCCTGCCACTTATTAT
GCAGTACAACATAGATATTATCCATTTTGGTGTAATCATGGTGGTCAACTTAACAATTGGTCTTTTAACCCCTCCATTAG
GTGTTAACTTGTTTGTTGCCAATGGTTTGCAAAAGGATCTTACATTATCGCAAGTTGTAAAAGCATCTCTTCCATTTATG
ATTTTCGCAATTATTGATTTAATGATCCTGACATATGTCCCTAATCTATCACTATACCTAACGCATTTACTAAAATAA

Upstream 100 bases:

>100_bases
TTGGGCTTACCTTAATGGGCATTCGTTATCTTATGATTTTAATTGAAAATATTACCGGAAAAAGTATATTAAGCTAAGTT
ATGTAGGAGGTAGATACCTA

Downstream 100 bases:

>100_bases
AATTTTGAAAATATGCGCTAAGGCATAAAATTCCTCAATTCAATTAAAAAATACAAAAAGCGAATGAGTACGGTTGAAGA
ATTACAACCGGAAAGTTCGC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MANILFTLFIIFVVLNVPIGIAIGLSTFGAILASQKVPLFLVAQRLFTGLDSFPLLAIPLFMIAGSLMESGGISKRLINF
ASNIVGPIPGGLAMVTVLACMFFAAISGSAPATVVAIGSIMVPAMIEAGYDKDFAVGLIAASGMIGVLIPPSIPFVTYGI
TMNASIGKLFLAGIVPGVLFGLSFMIISYFYAKKRGYKGTAKPTWKSFLTSFKEAIWALGMPAIILGGIYGGVFTPTEAA
AVACVYSLIVGFFIYRELTLQNMFKSFANAGVSSAMVGLIIAAATAMGWVLTTEQVPTNVATAISSIAHSKFMLLLLINL
ILLITGCLMELNAAIIILGPIFLPLIMQYNIDIIHFGVIMVVNLTIGLLTPPLGVNLFVANGLQKDLTLSQVVKASLPFM
IFAIIDLMILTYVPNLSLYLTHLLK

Sequences:

>Translated_425_residues
MANILFTLFIIFVVLNVPIGIAIGLSTFGAILASQKVPLFLVAQRLFTGLDSFPLLAIPLFMIAGSLMESGGISKRLINF
ASNIVGPIPGGLAMVTVLACMFFAAISGSAPATVVAIGSIMVPAMIEAGYDKDFAVGLIAASGMIGVLIPPSIPFVTYGI
TMNASIGKLFLAGIVPGVLFGLSFMIISYFYAKKRGYKGTAKPTWKSFLTSFKEAIWALGMPAIILGGIYGGVFTPTEAA
AVACVYSLIVGFFIYRELTLQNMFKSFANAGVSSAMVGLIIAAATAMGWVLTTEQVPTNVATAISSIAHSKFMLLLLINL
ILLITGCLMELNAAIIILGPIFLPLIMQYNIDIIHFGVIMVVNLTIGLLTPPLGVNLFVANGLQKDLTLSQVVKASLPFM
IFAIIDLMILTYVPNLSLYLTHLLK
>Mature_424_residues
ANILFTLFIIFVVLNVPIGIAIGLSTFGAILASQKVPLFLVAQRLFTGLDSFPLLAIPLFMIAGSLMESGGISKRLINFA
SNIVGPIPGGLAMVTVLACMFFAAISGSAPATVVAIGSIMVPAMIEAGYDKDFAVGLIAASGMIGVLIPPSIPFVTYGIT
MNASIGKLFLAGIVPGVLFGLSFMIISYFYAKKRGYKGTAKPTWKSFLTSFKEAIWALGMPAIILGGIYGGVFTPTEAAA
VACVYSLIVGFFIYRELTLQNMFKSFANAGVSSAMVGLIIAAATAMGWVLTTEQVPTNVATAISSIAHSKFMLLLLINLI
LLITGCLMELNAAIIILGPIFLPLIMQYNIDIIHFGVIMVVNLTIGLLTPPLGVNLFVANGLQKDLTLSQVVKASLPFMI
FAIIDLMILTYVPNLSLYLTHLLK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=409, Percent_Identity=38.8753056234719, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45066; Mature: 44935

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILFTLFIIFVVLNVPIGIAIGLSTFGAILASQKVPLFLVAQRLFTGLDSFPLLAIPL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
FMIAGSLMESGGISKRLINFASNIVGPIPGGLAMVTVLACMFFAAISGSAPATVVAIGSI
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
MVPAMIEAGYDKDFAVGLIAASGMIGVLIPPSIPFVTYGITMNASIGKLFLAGIVPGVLF
HHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
GLSFMIISYFYAKKRGYKGTAKPTWKSFLTSFKEAIWALGMPAIILGGIYGGVFTPTEAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
AVACVYSLIVGFFIYRELTLQNMFKSFANAGVSSAMVGLIIAAATAMGWVLTTEQVPTNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHH
ATAISSIAHSKFMLLLLINLILLITGCLMELNAAIIILGPIFLPLIMQYNIDIIHFGVIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVNLTIGLLTPPLGVNLFVANGLQKDLTLSQVVKASLPFMIFAIIDLMILTYVPNLSLYL
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
THLLK
HHHCC
>Mature Secondary Structure 
ANILFTLFIIFVVLNVPIGIAIGLSTFGAILASQKVPLFLVAQRLFTGLDSFPLLAIPL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHH
FMIAGSLMESGGISKRLINFASNIVGPIPGGLAMVTVLACMFFAAISGSAPATVVAIGSI
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
MVPAMIEAGYDKDFAVGLIAASGMIGVLIPPSIPFVTYGITMNASIGKLFLAGIVPGVLF
HHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHH
GLSFMIISYFYAKKRGYKGTAKPTWKSFLTSFKEAIWALGMPAIILGGIYGGVFTPTEAA
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
AVACVYSLIVGFFIYRELTLQNMFKSFANAGVSSAMVGLIIAAATAMGWVLTTEQVPTNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHH
ATAISSIAHSKFMLLLLINLILLITGCLMELNAAIIILGPIFLPLIMQYNIDIIHFGVIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVNLTIGLLTPPLGVNLFVANGLQKDLTLSQVVKASLPFMIFAIIDLMILTYVPNLSLYL
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
THLLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]