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The map label for this gene is cbiL [H]

Identifier: 78042761

GI number: 78042761

Start: 670318

End: 670977

Strand: Direct

Name: cbiL [H]

Synonym: CHY_0761

Alternate gene names: 78042761

Gene position: 670318-670977 (Clockwise)

Preceding gene: 78045065

Following gene: 78044806

Centisome position: 27.91

GC content: 41.67

Gene sequence:

>660_bases
ATGGCTAAACTTTACGTGGTTGGTGTTGGTCCGGGGGACCCCGAGCTTATTACGGTGAAAGCTATGAAGATTTTGCGAGG
GGTACGGGTTTTAGTTTTTCCCGGAAAAAGGGCTTTTAAAGTTGTGGAAAGTTTTCTTTCAGATGATAAAGAAATTCTCT
TTTTTAATTTTCCCATGGTGGAAGACGAGGGGCAAAAACGGGAAGCGGCGCACACCTTTGCCCAAAAAATTTTAGAGTAT
TTAAACCGGGAAGAAGTTTCTTTTTTTACCCTGGGAGACCCGGGTTTATACAGTACCGCTGGATATTTATTGGAGGCGCT
AAAACAGTTAGGTTTTGCAGGGGATATAGAAATAGTTCCGGGGATAAATTCCTTTTCACTGGCAGCCGCTAAGTCTTTCT
TTAACCTGGCTTTTGAAGATGAAAAGGTAGAAATCCTATCGACTTTGCCGGAAGATTTTACTTTTGAGCCCAAAACTACC
TATGTTTTTTTAAAACTTTCCTCCTATTACGACCGCTTTTTAGAGCTGGTAAAGGAAGCAAAGATCCAGGGATATTATTT
TAAAGAGCTTGGTACCGAAGAGGAAAAAATCTGTTCTTTTAATGAACTTCCCGAAAAAACCGGGTATTTTTCCCTGGCCC
TGGCGAAGAGGGGGACTTAG

Upstream 100 bases:

>100_bases
AGCATAGCGGTTACCAGGTTTAAAAAAGCAGGAAGCTATCATATCCTGAATGCGCAAAATCCCGTATTTATCTTTACCGG
AAGGAAAAAGGGGGAAAAAA

Downstream 100 bases:

>100_bases
CCGTGAAAGTTTATTTAGTAGGCGCCGGACCTGGAGATCCCGAGTTAATAACTGTTAAAGGGAAAAAACTTTTAGAGGAA
GCTGATTTAATTGTTTATGC

Product: putative precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAKLYVVGVGPGDPELITVKAMKILRGVRVLVFPGKRAFKVVESFLSDDKEILFFNFPMVEDEGQKREAAHTFAQKILEY
LNREEVSFFTLGDPGLYSTAGYLLEALKQLGFAGDIEIVPGINSFSLAAAKSFFNLAFEDEKVEILSTLPEDFTFEPKTT
YVFLKLSSYYDRFLELVKEAKIQGYYFKELGTEEEKICSFNELPEKTGYFSLALAKRGT

Sequences:

>Translated_219_residues
MAKLYVVGVGPGDPELITVKAMKILRGVRVLVFPGKRAFKVVESFLSDDKEILFFNFPMVEDEGQKREAAHTFAQKILEY
LNREEVSFFTLGDPGLYSTAGYLLEALKQLGFAGDIEIVPGINSFSLAAAKSFFNLAFEDEKVEILSTLPEDFTFEPKTT
YVFLKLSSYYDRFLELVKEAKIQGYYFKELGTEEEKICSFNELPEKTGYFSLALAKRGT
>Mature_218_residues
AKLYVVGVGPGDPELITVKAMKILRGVRVLVFPGKRAFKVVESFLSDDKEILFFNFPMVEDEGQKREAAHTFAQKILEYL
NREEVSFFTLGDPGLYSTAGYLLEALKQLGFAGDIEIVPGINSFSLAAAKSFFNLAFEDEKVEILSTLPEDFTFEPKTTY
VFLKLSSYYDRFLELVKEAKIQGYYFKELGTEEEKICSFNELPEKTGYFSLALAKRGT

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 24763; Mature: 24632

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYVVGVGPGDPELITVKAMKILRGVRVLVFPGKRAFKVVESFLSDDKEILFFNFPMV
CCEEEEEEECCCCCCEEEHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCEE
EDEGQKREAAHTFAQKILEYLNREEVSFFTLGDPGLYSTAGYLLEALKQLGFAGDIEIVP
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
GINSFSLAAAKSFFNLAFEDEKVEILSTLPEDFTFEPKTTYVFLKLSSYYDRFLELVKEA
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
KIQGYYFKELGTEEEKICSFNELPEKTGYFSLALAKRGT
HCCCEEHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
AKLYVVGVGPGDPELITVKAMKILRGVRVLVFPGKRAFKVVESFLSDDKEILFFNFPMV
CEEEEEEECCCCCCEEEHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCEE
EDEGQKREAAHTFAQKILEYLNREEVSFFTLGDPGLYSTAGYLLEALKQLGFAGDIEIVP
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
GINSFSLAAAKSFFNLAFEDEKVEILSTLPEDFTFEPKTTYVFLKLSSYYDRFLELVKEA
CCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
KIQGYYFKELGTEEEKICSFNELPEKTGYFSLALAKRGT
HCCCEEHHHCCCCHHHHCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]