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The map label for this gene is fabH [H]

Identifier: 77761158

GI number: 77761158

Start: 2009709

End: 2010707

Strand: Direct

Name: fabH [H]

Synonym: XC_1672

Alternate gene names: 77761158

Gene position: 2009709-2010707 (Clockwise)

Preceding gene: 66767995

Following gene: 66767997

Centisome position: 39.03

GC content: 69.37

Gene sequence:

>999_bases
TTGAACGCATTGCCGCTGCGCATCCTGGGCACCGGGTGCCACGTTCCCGCCACGGAAGTGACGTCGCAAGAACTGGACGC
ACGCTGGCAGTTGCCGCCGGGAACCACGTTCGCGCGGCTGGGCGTCGCCACGCGCCACTATGCAGGCGAGGGCGAAACGG
CCTCGTCCATGGGCGCCGCCGCCGCGCAAGCGGCATTGGTCAGCGCCGGTATCGATAGCGGCGAGATCGACTGCCTGATC
TCCGCCTGCAGCGTGATGGAGCAGCCGATCCCGTGCCAGGCAGTGCTGATCCAGCGTGCCCTGGGGCTGGGTGACTCTGG
CATCCCGGCATTCGATGTCAACGCCACCTGCCTGAGTTTTCTGGTCGCATTGGACATGGCCACAAACGCGCTGGCCCTGG
GCCGCTATCGCCGCGTGCTCATCGTCTCCAGCGAAGTGGCGTCGGGCGGGCTGGATGCGGCGGTGCCATCGACCGCCGGC
TTGTTCGGCGATGGCGCTGCCGCCGTGGTGGTCGGGCGCAGCGCGCCTGACGAAGACTCGGCGCTGCTGTCCAGCCGCCT
GGCCAGCTACGGCAGCGGTGCCGAGCTGTGCCGCATCCGCGGTGGCGGCAGCCGCTATCCGCGTGGCGAAGACAGCACGC
CCGAAGCCACGCGGGTCTTCACCATGGATGGGCGCGGTGCGTATCGCTTTGCGGCGCGCCACCTGCCGGCGTTCTGGGAC
CAGCTGCTGCGCGACGCCGGTACCGAGACCACCGCACTGCGCTGCCTGATCCCGCATCAAGCCTCCGGTGGCGGCCTGGA
TCATGTGGTGCAGGCGCTCGGCCTGCGCCCGGAGCAGGTGGTGCGCATCCTGCACGCGCATGGCAACCAGGTGGCGGCAT
CGCTGCCACACGCGCTGCATCAGGCCAGGGTCACGCAGCAGCTGCAGCGCGGCGAACTATTCGCGATGCTCGGCACCGGT
GCCGGCCTGTCGATCGGCGGCATGGTGTTGAGGTACTGA

Upstream 100 bases:

>100_bases
CGCCGTGCAAGCCCCACGACTGCGCCAACATTGCGCAGGCAGCTGGGTCTGCCTGGCCGGCCACGGTATGCTGCGCGCCT
TCACCAACGAGGCGGATCTG

Downstream 100 bases:

>100_bases
TGGCGACGCGGGTCTCGGTCGAGTTGTTGCGCATCGGGCATTGCCACCACTGCGAACGCATGGTGCGCGCGGACGGGCAT
TGGCATTCAGTGGAATTCCC

Product: GumO

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNALPLRILGTGCHVPATEVTSQELDARWQLPPGTTFARLGVATRHYAGEGETASSMGAAAAQAALVSAGIDSGEIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMATNALALGRYRRVLIVSSEVASGGLDAAVPSTAG
LFGDGAAAVVVGRSAPDEDSALLSSRLASYGSGAELCRIRGGGSRYPRGEDSTPEATRVFTMDGRGAYRFAARHLPAFWD
QLLRDAGTETTALRCLIPHQASGGGLDHVVQALGLRPEQVVRILHAHGNQVAASLPHALHQARVTQQLQRGELFAMLGTG
AGLSIGGMVLRY

Sequences:

>Translated_332_residues
MNALPLRILGTGCHVPATEVTSQELDARWQLPPGTTFARLGVATRHYAGEGETASSMGAAAAQAALVSAGIDSGEIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMATNALALGRYRRVLIVSSEVASGGLDAAVPSTAG
LFGDGAAAVVVGRSAPDEDSALLSSRLASYGSGAELCRIRGGGSRYPRGEDSTPEATRVFTMDGRGAYRFAARHLPAFWD
QLLRDAGTETTALRCLIPHQASGGGLDHVVQALGLRPEQVVRILHAHGNQVAASLPHALHQARVTQQLQRGELFAMLGTG
AGLSIGGMVLRY
>Mature_332_residues
MNALPLRILGTGCHVPATEVTSQELDARWQLPPGTTFARLGVATRHYAGEGETASSMGAAAAQAALVSAGIDSGEIDCLI
SACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSFLVALDMATNALALGRYRRVLIVSSEVASGGLDAAVPSTAG
LFGDGAAAVVVGRSAPDEDSALLSSRLASYGSGAELCRIRGGGSRYPRGEDSTPEATRVFTMDGRGAYRFAARHLPAFWD
QLLRDAGTETTALRCLIPHQASGGGLDHVVQALGLRPEQVVRILHAHGNQVAASLPHALHQARVTQQLQRGELFAMLGTG
AGLSIGGMVLRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=31.2883435582822, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34436; Mature: 34436

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPLRILGTGCHVPATEVTSQELDARWQLPPGTTFARLGVATRHYAGEGETASSMGAA
CCCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCCHHHHHCCHHHHCCCCCCCHHHHHHH
AAQAALVSAGIDSGEIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSF
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHH
LVALDMATNALALGRYRRVLIVSSEVASGGLDAAVPSTAGLFGDGAAAVVVGRSAPDEDS
HHHHHHHHHHHHHHCCEEEEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHH
ALLSSRLASYGSGAELCRIRGGGSRYPRGEDSTPEATRVFTMDGRGAYRFAARHLPAFWD
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCHHHHH
QLLRDAGTETTALRCLIPHQASGGGLDHVVQALGLRPEQVVRILHAHGNQVAASLPHALH
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
QARVTQQLQRGELFAMLGTGAGLSIGGMVLRY
HHHHHHHHHCCCEEEEEECCCCCCCCCEEECC
>Mature Secondary Structure
MNALPLRILGTGCHVPATEVTSQELDARWQLPPGTTFARLGVATRHYAGEGETASSMGAA
CCCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCCHHHHHCCHHHHCCCCCCCHHHHHHH
AAQAALVSAGIDSGEIDCLISACSVMEQPIPCQAVLIQRALGLGDSGIPAFDVNATCLSF
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHH
LVALDMATNALALGRYRRVLIVSSEVASGGLDAAVPSTAGLFGDGAAAVVVGRSAPDEDS
HHHHHHHHHHHHHHCCEEEEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHH
ALLSSRLASYGSGAELCRIRGGGSRYPRGEDSTPEATRVFTMDGRGAYRFAARHLPAFWD
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCHHHHH
QLLRDAGTETTALRCLIPHQASGGGLDHVVQALGLRPEQVVRILHAHGNQVAASLPHALH
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
QARVTQQLQRGELFAMLGTGAGLSIGGMVLRY
HHHHHHHHHCCCEEEEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA