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The map label for this gene is add [H]

Identifier: 77761081

GI number: 77761081

Start: 360801

End: 362363

Strand: Reverse

Name: add [H]

Synonym: XC_0304

Alternate gene names: 77761081

Gene position: 362363-360801 (Counterclockwise)

Preceding gene: 66766649

Following gene: 66766647

Centisome position: 7.04

GC content: 67.56

Gene sequence:

>1563_bases
ATGCTGCGTCGTTGTCTGATCCTCACCGTGTGCGCGCTGCTGCCCGCACTTGCGCAGGCGCGCCAAACGCCTGCGCCCGC
ACAATCGCGCGAGCAGCAGGTTGCGCAGTTGTTTCGCGATACGGCCGGCCAATCGGCGCAACTGCGCAGTTGGTTGCAGG
CCATGCCCAAAGGCGGCGACCTGCATAACCATCTCTCCGGCTCGGTGTATGCCGAGGACTACCTGCAGTGGGCCAGCGAA
GACGGCGCCTGCGTGCAGCTGGACGACCTGAGCCTGCGCGCACCGCCGTGCGTGGCCGGCCAGGTGCCCGCACGCGGGCT
GTCCACGCGCGATGTCGCGCTGTATGGCCGGGTGGTGGATGCCTTGTCGATGCGCAACCACCTGGCCAGCCCATCCCAAC
CCACCGGGCACGGGCAGTTCTTCAGCACCTTCGGCAAGTTCGATGCGGTGGTGCGCGCACGCGTGGCCGACACCGTGGCC
GCCGTGCTGGAGCAGGCCGCGCGCGACCGCGTGCCGTACGTGGAAATCATCGCCAACCCACCACAGATGGACGACGCTGC
GCAGCGCATGCAGGCGCTGCCCTGGCATGGCACCGACGATGCCGCAAACCTGCGCGAACTGCAGGACGCGCTGCCACCGC
TGGTGCAGGCCGCACAGCGCAACCTTGCCGACCTCGACGCGCAGGTGCGCCACGTCCTGCAGTGTGACCAGGCGCAGCCA
CGCGCGGCCTGCCAGGTGCAGTACCGCTATGTGCCGTATGTGTTGCGTGTGCTGCCTGCGCCGCAGGTGTTCGGGCAGAT
GGCGCTCGCCCATGCGCTCGTGGCCGCCGGCGGCAGCCGCGCGGTGGCGGTGAACATCGTCGCGCCCGAGGACAACCCGG
TGGCAGTGGCCGATTACGCGCGCCACATGGCGATGTTCCGGTTCTTCGCACAGCGCTACCCCGGCGTGCCGTTGTCCTTG
CATGCCGGCGAGCTGACCCTGGGCCTGGTGCCACCGGCGCAGCTGCGCTCGCATATCCGCCAGGCGGTGGATGCCGGTGC
GCGGCGCATCGGTCATGGCGTGGATCTGCCTTACGAAGACGACGCGCAAGAGCTGCTGCAGCGCATGCGCCGCGACCAGG
TAGCGGTGGAGATCAACCTCACCAGTAACGATGTGATCCTGGGCGTCACCGGGGCCGCGCATCCGTTGGCCATGTATCTG
CGCGCGGGTGTGCCGGTGGTGCTCTCCACCGACGATGCCGGCGTGTCGCGCGCGGACATGACCCACGAATATCAACGCGC
CGTGCAGGAGCAGGGCATCGAGTACCCCACGCTCAAGCAACTCGCCCGCAACGGGCTGACGTACAGCTTCCTGCCGGGCG
CGAGCCTGTGGAGCGCCAACGGTAAAGCTGCGCAGGCCTGCGCCACTGCATTACAGCGCGAAACCGATGATGCTGGGTGC
CAAGCATTTCGCCAGAGCAGCGAGAAGGCACGGCTGCAATGGCAGCTTGAAACCGATCTGGCGCAGTACGAGCGCATGCT
GATGGAGCAGCGCAAAGTGCAGACAACACCAGCTGACGCATAA

Upstream 100 bases:

>100_bases
GCAGCGCGCTGGCCGTGCAACACACTGCAAGGCAAGCTACCCCTCCGCTGGGCGCGCATGCGCGCCGGCACACCTTCTTG
CGAGTTTTTTCTGTATGCCC

Downstream 100 bases:

>100_bases
CCCATAGGAGCGCGCTCAGCGAAGGAGGCTTCACCGATAACGCCTCATCGCGCGCCACGTCCTACAACGCGACTTCCGCT
GCATCGCCGCTGCAATACAT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MLRRCLILTVCALLPALAQARQTPAPAQSREQQVAQLFRDTAGQSAQLRSWLQAMPKGGDLHNHLSGSVYAEDYLQWASE
DGACVQLDDLSLRAPPCVAGQVPARGLSTRDVALYGRVVDALSMRNHLASPSQPTGHGQFFSTFGKFDAVVRARVADTVA
AVLEQAARDRVPYVEIIANPPQMDDAAQRMQALPWHGTDDAANLRELQDALPPLVQAAQRNLADLDAQVRHVLQCDQAQP
RAACQVQYRYVPYVLRVLPAPQVFGQMALAHALVAAGGSRAVAVNIVAPEDNPVAVADYARHMAMFRFFAQRYPGVPLSL
HAGELTLGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAQELLQRMRRDQVAVEINLTSNDVILGVTGAAHPLAMYL
RAGVPVVLSTDDAGVSRADMTHEYQRAVQEQGIEYPTLKQLARNGLTYSFLPGASLWSANGKAAQACATALQRETDDAGC
QAFRQSSEKARLQWQLETDLAQYERMLMEQRKVQTTPADA

Sequences:

>Translated_520_residues
MLRRCLILTVCALLPALAQARQTPAPAQSREQQVAQLFRDTAGQSAQLRSWLQAMPKGGDLHNHLSGSVYAEDYLQWASE
DGACVQLDDLSLRAPPCVAGQVPARGLSTRDVALYGRVVDALSMRNHLASPSQPTGHGQFFSTFGKFDAVVRARVADTVA
AVLEQAARDRVPYVEIIANPPQMDDAAQRMQALPWHGTDDAANLRELQDALPPLVQAAQRNLADLDAQVRHVLQCDQAQP
RAACQVQYRYVPYVLRVLPAPQVFGQMALAHALVAAGGSRAVAVNIVAPEDNPVAVADYARHMAMFRFFAQRYPGVPLSL
HAGELTLGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAQELLQRMRRDQVAVEINLTSNDVILGVTGAAHPLAMYL
RAGVPVVLSTDDAGVSRADMTHEYQRAVQEQGIEYPTLKQLARNGLTYSFLPGASLWSANGKAAQACATALQRETDDAGC
QAFRQSSEKARLQWQLETDLAQYERMLMEQRKVQTTPADA
>Mature_520_residues
MLRRCLILTVCALLPALAQARQTPAPAQSREQQVAQLFRDTAGQSAQLRSWLQAMPKGGDLHNHLSGSVYAEDYLQWASE
DGACVQLDDLSLRAPPCVAGQVPARGLSTRDVALYGRVVDALSMRNHLASPSQPTGHGQFFSTFGKFDAVVRARVADTVA
AVLEQAARDRVPYVEIIANPPQMDDAAQRMQALPWHGTDDAANLRELQDALPPLVQAAQRNLADLDAQVRHVLQCDQAQP
RAACQVQYRYVPYVLRVLPAPQVFGQMALAHALVAAGGSRAVAVNIVAPEDNPVAVADYARHMAMFRFFAQRYPGVPLSL
HAGELTLGLVPPAQLRSHIRQAVDAGARRIGHGVDLPYEDDAQELLQRMRRDQVAVEINLTSNDVILGVTGAAHPLAMYL
RAGVPVVLSTDDAGVSRADMTHEYQRAVQEQGIEYPTLKQLARNGLTYSFLPGASLWSANGKAAQACATALQRETDDAGC
QAFRQSSEKARLQWQLETDLAQYERMLMEQRKVQTTPADA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Escherichia coli, GI1787910, Length=324, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 56723; Mature: 56723

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCHHEEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHCCCHHEEEEEHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]