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The map label for this gene is yicO [C]

Identifier: 66766649

GI number: 66766649

Start: 362493

End: 363806

Strand: Reverse

Name: yicO [C]

Synonym: XC_0305

Alternate gene names: 66766649

Gene position: 363806-362493 (Counterclockwise)

Preceding gene: 66766651

Following gene: 77761081

Centisome position: 7.07

GC content: 68.49

Gene sequence:

>1314_bases
ATGCGCTGGCCCAACTTTGCGCTTGCCGCCAACGGCAGCAACGTGCGCACCGAGCTGCTGGCCGGCGCCACCACCTTCCT
CACGATGGCCTACATCGTGTTCGTCAACCCGGACATCCTGGCCACTACCGGCATGGATCACGGCGCGGTGTTTGTGGCCA
CCTGCCTGGCCGCGGCATTCGGCTCGGCGGTGATGGGCCTGCTGGCCAATTACCCGATCGGCATGGCGCCCGGCATGGGC
TTGAACGCCTTCTTCGCCTTCAGCGTGGTGGGCACCCTGGGCTACAGCTGGCAACAGACGCTGGGCCTGGTGTTCGTGTC
CGGCTGCGTGTTCCTGCTGCTCACCCTCACCGGCGCGCGCCGGTGGCTGGTGGACGGCATCCCCACCACGTTACGCAGCG
CAATCGCCGCCGGTATCGGCCTGTTCCTGGCGGTGATCGGCCTGCAGAAAGCCGGGCTGGTGGTGGCCCACCCGCAGACC
TTGATCACCCTGGGCGACCTGCACCGGCCCGAGCCCTTGCTGGCGTTGGCCGGGTTGCTGCTGATCGGCGTGCTGGAGCT
GCGGCGCGTGCGCGGGGCGATGCTGCTCGGCATCCTGGCGGTCACCGCTGCGGCACTCGCACTCGGGCTGGTGCAGTACC
GGGGCGTGATCGCGCTGCCGCCGAGTCTGGCACCCACCTTGCTGAAACTGGATATTGCCGGTGCCCTGCAGGGCCACGCT
GGCGAAGGCGCATTGACCGCGGTACTGCACGTGGTGCTGGTGTTCGTGCTGGTGGAGATGTTCGATGCCACCGGCACCTT
GATGGGGGTGGCGCAGCGCGCCGGCTTGCTGCGCACCACAGCCCAGCGCCGCCAGTTCGACCGCGCTCTGCTCGCCGACA
GCAGCGCCATCCTGGCCGGCTCGCTGCTTGGCACCTCCAGCACCACGGCCTATGTGGAAAGCGCCGCTGGCGTGCAGGTG
GGTGGGCGCACCGGGCTGACCGCGCTGGTGGTGGCCGCGCTGTTCCTGCTGGCCCTGCTGTTCTCGCCGCTGGCAGCCAT
GGTGCCGGCCTACGCCACCGCACCGGCGTTGCTGTATCTGGCGGCAGTGATGCTGCGCGAGTGCGCGCATCTGCAGTGGG
ACGATGTCGGCGAAGCGTTGCCGGCCGCCATGTGCATGCTGGCGATGCCCTTCACCTATTCGATCGCCAATGGGTTGGCG
TTGGGCTTCATCACCTATGCGGTGCTCCGGCTAGGCAGCGGGCGTTGGCGTGAGGTGCATCCAGCCACCTGGGCCATCGC
TGGCCTGTTCGTGCTGCGCTATGCGCTGGAGTGA

Upstream 100 bases:

>100_bases
ACGCAGCCCGCGCTTACGCGCCGGTGCCTGTGTTCGATGAGATGTTGCCGATGACACTGTTCTGCTGTGCCGCCGCTTGC
CGGCCGCTGGGGCGCGCCTG

Downstream 100 bases:

>100_bases
CGCGCCTGCACCGCGCTGCCTGCAGGCACGCAGCGCGCTGGCCGTGCAACACACTGCAAGGCAAGCTACCCCTCCGCTGG
GCGCGCATGCGCGCCGGCAC

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MRWPNFALAANGSNVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAFGSAVMGLLANYPIGMAPGMG
LNAFFAFSVVGTLGYSWQQTLGLVFVSGCVFLLLTLTGARRWLVDGIPTTLRSAIAAGIGLFLAVIGLQKAGLVVAHPQT
LITLGDLHRPEPLLALAGLLLIGVLELRRVRGAMLLGILAVTAAALALGLVQYRGVIALPPSLAPTLLKLDIAGALQGHA
GEGALTAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLRTTAQRRQFDRALLADSSAILAGSLLGTSSTTAYVESAAGVQV
GGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALLYLAAVMLRECAHLQWDDVGEALPAAMCMLAMPFTYSIANGLA
LGFITYAVLRLGSGRWREVHPATWAIAGLFVLRYALE

Sequences:

>Translated_437_residues
MRWPNFALAANGSNVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAFGSAVMGLLANYPIGMAPGMG
LNAFFAFSVVGTLGYSWQQTLGLVFVSGCVFLLLTLTGARRWLVDGIPTTLRSAIAAGIGLFLAVIGLQKAGLVVAHPQT
LITLGDLHRPEPLLALAGLLLIGVLELRRVRGAMLLGILAVTAAALALGLVQYRGVIALPPSLAPTLLKLDIAGALQGHA
GEGALTAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLRTTAQRRQFDRALLADSSAILAGSLLGTSSTTAYVESAAGVQV
GGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALLYLAAVMLRECAHLQWDDVGEALPAAMCMLAMPFTYSIANGLA
LGFITYAVLRLGSGRWREVHPATWAIAGLFVLRYALE
>Mature_437_residues
MRWPNFALAANGSNVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAFGSAVMGLLANYPIGMAPGMG
LNAFFAFSVVGTLGYSWQQTLGLVFVSGCVFLLLTLTGARRWLVDGIPTTLRSAIAAGIGLFLAVIGLQKAGLVVAHPQT
LITLGDLHRPEPLLALAGLLLIGVLELRRVRGAMLLGILAVTAAALALGLVQYRGVIALPPSLAPTLLKLDIAGALQGHA
GEGALTAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLRTTAQRRQFDRALLADSSAILAGSLLGTSSTTAYVESAAGVQV
GGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALLYLAAVMLRECAHLQWDDVGEALPAAMCMLAMPFTYSIANGLA
LGFITYAVLRLGSGRWREVHPATWAIAGLFVLRYALE

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=431, Percent_Identity=45.0116009280742, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=46.8531468531469, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI48994909, Length=437, Percent_Identity=39.5881006864989, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790499, Length=438, Percent_Identity=39.4977168949772, Blast_Score=251, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45483; Mature: 45483

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWPNFALAANGSNVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAF
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GSAVMGLLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQTLGLVFVSGCVFLLLTLTGAR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
RWLVDGIPTTLRSAIAAGIGLFLAVIGLQKAGLVVAHPQTLITLGDLHRPEPLLALAGLL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHEEECCCCCCCHHHHHHHHH
LIGVLELRRVRGAMLLGILAVTAAALALGLVQYRGVIALPPSLAPTLLKLDIAGALQGHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCC
GEGALTAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLRTTAQRRQFDRALLADSSAILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALLYL
HHHCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVMLRECAHLQWDDVGEALPAAMCMLAMPFTYSIANGLALGFITYAVLRLGSGRWREVH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PATWAIAGLFVLRYALE
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRWPNFALAANGSNVRTELLAGATTFLTMAYIVFVNPDILATTGMDHGAVFVATCLAAAF
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHH
GSAVMGLLANYPIGMAPGMGLNAFFAFSVVGTLGYSWQQTLGLVFVSGCVFLLLTLTGAR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
RWLVDGIPTTLRSAIAAGIGLFLAVIGLQKAGLVVAHPQTLITLGDLHRPEPLLALAGLL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHEEECCCCCCCHHHHHHHHH
LIGVLELRRVRGAMLLGILAVTAAALALGLVQYRGVIALPPSLAPTLLKLDIAGALQGHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCC
GEGALTAVLHVVLVFVLVEMFDATGTLMGVAQRAGLLRTTAQRRQFDRALLADSSAILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
SLLGTSSTTAYVESAAGVQVGGRTGLTALVVAALFLLALLFSPLAAMVPAYATAPALLYL
HHHCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVMLRECAHLQWDDVGEALPAAMCMLAMPFTYSIANGLALGFITYAVLRLGSGRWREVH
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PATWAIAGLFVLRYALE
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]