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The map label for this gene is yeaD [H]

Identifier: 77748773

GI number: 77748773

Start: 5077186

End: 5079348

Strand: Reverse

Name: yeaD [H]

Synonym: XAC4296

Alternate gene names: 77748773

Gene position: 5079348-5077186 (Counterclockwise)

Preceding gene: 21245009

Following gene: 21245007

Centisome position: 98.14

GC content: 70.46

Gene sequence:

>2163_bases
ATGACGCTGTCCCGGGGCGCGTTGCCGTTCGTGTTGGGACTGCTGCCGCTGGCGGCCTGCGCCGATCCGGCCTTCGATCG
CTGCCTGGCTGGCCTGCAGACGCAGGCCGCTGCCAAGGGCGTGGACGCTGCCAGCTTTCAGCGCTTCACCGCCGGGCTGG
CGCCCGATTCCAGCGTCCTGCCGCTGCTGGATGCGCAGCCCGAATTCACCACGCCCATCTGGGACTACCTGGCCAGCCTG
GTCGACAGCCAGCGCGTCACCGATGGCCAGGCCATGCTGGTCACCCACCGCGAACTGCTCAGCCGCCTGTCCGATCAAAC
CGGCGTGGACCCAGCCACCATCGTGGCGGTGTGGGGCGTGGAGAGCGATTACGGCCGCGTCACCGGTAAGCGCCCGCTGC
TGGTATCGCTGGCCACGCTGTCGTGCGCGGGCCGTCGCCAGCCGTTCTTTCGTGGCGAATTCCTCGCCTTGCTCAGCCTG
CTGCAGCAAGGCGATCTGTCGGCGGACGGCCTCACCGGCTCCTGGGCCGGCGCGTTCGGGCAGACCCAGTTCATGCCTTC
GACCTACGCCCGCATCGCGGTGGATGGCGACGGCGACGGCCGCCGCGATCTGGTGACCAGCATTCCCGATGCACTGGCCT
CCACCGCCAACTACCTGGTCAAGGCCGGCTGGGAACGCGCCCGTCCGTGGGGCATGGAAGTCACCCTGCCGCGCGGTTTC
GACGCCAGCAAGGCCGGGCGCACCCGCCGCCAACCGCTGCAGGCCTGGCAAAGCGCCGGCCTGCTCGGCACCGACGGCAA
ACCGCTGGCACCAACCGGGCTGCCGGCAGAAACGCCGGCCGCCTTGCTGCTGCCGGCCGGCGCCACCGGCCCGGCGTTCC
TGGTGTTCCGCAACTACGACGCGATCTACGCCTACAACGCCGCCGAAAGTTACGCGCTGTCCATCGCCCTGCTCGCCGAT
CGCCTGCGTGGCGGCGCGGGCCTGATCGCGGCCTGGCCTACCGACGATCCCGGCCTGGGCCGGCCCGAACGACGCGAACT
GCAGCAGTTGCTGCTCGCCCGCGGCTACCAGATCGGCGAGGCCGACGGCATGGTCGGCAGCGCCACCCGCCGCGCCATCC
AGGTCGAGCAGACCCGCCTGGGCCTGCAACCGGCCGACGGCCGTCCGGGCCAACGCATCCTCGCCGCGTTGCGCGCCGCC
CCGCCGGTCGCCGGCGCCGCCGCCATGCGCGCCACCGCGTTCAAGCTGCCGGCCGCATACCCGGCCTTCGCCCAATCCCC
CAGCGTCCAAAAGGCATCCCCCATGTCCGACACCACCGGCCTGACCACAGGCGATTTCCATGGGTTTCCGTCGTTGCTGA
TCGACACCCCGTTCTCCACCGCCGCCATCAGCCTGTTCGGTGGCCAGCTGCTCTCGTTCGTGCCCGAGGGCGGACAGGAC
GTGATGTGGCTTTCGCCCAGCGCCCAGCAACCGCCTACCCCGATCCGCGGCGGTGCGCCGGTGTGCTGGCCGTATTTCGG
CCGCCAGGACCAGGCCGGCGACGTTCCCGCCCACGGGTTCGTGCGCACGGTGGCCTGGCAACTCACCGAAAGCCACCGCG
AAGACGACGGCACCGTGGTGCTCACGCTCACCCCGCCGCGCTTCGACGACCTGGCGCTGCGCCTGCGCATGACCCTGCGC
ATCGGCCGCACGCTGGAGCAACGCCTGATCACTGAAAACACCAGCGTCGCCCCGGTGCGTTTCACCCAGGCGTTGCACAA
CTACTTCCGTGTCGGCGACGCGCTCAAGGTCAGCGTGCAGGGCCTGGATGGCCTGGACTATCTGGATAAATACGAGAACT
ACGCCACCGCCCACCGCCAGCAAGGCGACTGGAGCCTGCGCGACCCACGCGACCCCGGTCGTAGCGACCGCATCTACACC
AACGCCGGCGGCCGCTACACGCTCACCGACCCGGTGCTCGGTCGCCGCATCGTCATCGCCACCGAAGGCAGCCGCTCGCT
GGTGGCCTGGAACCCGGGCGAAGACGCCGGCAAGAAGATGGCCGACGTGGGCGAGGGCTGGCGCGACTACGTCTGCCTGG
AAGCGGCCAATGCCGGCCCGGACGTCATCGAGCTCGCCCCCGGCGCCAGCCACACCCTGACCCAGACCATCAGCGTCGAG
TAG

Upstream 100 bases:

>100_bases
CACGCCTGCCACCACCCAGGTTGGCTATGCTCGGCGGCCCGACTTGTCGCGCAGGAGCGCTTCACCGCATGACGTCTGCC
CACCCGCCGGCCATCGCGCC

Downstream 100 bases:

>100_bases
CCGCCCAGGCCCGCGCTGCTTTCTACGCCAATAAAAGCAGCAGAGGCTTCCTTCTCCCACCGGGACCTTGTCCCCTTCAT
GGGGAGGGAAGGTGCCCGTA

Product: epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MTLSRGALPFVLGLLPLAACADPAFDRCLAGLQTQAAAKGVDAASFQRFTAGLAPDSSVLPLLDAQPEFTTPIWDYLASL
VDSQRVTDGQAMLVTHRELLSRLSDQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSL
LQQGDLSADGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
DASKAGRTRRQPLQAWQSAGLLGTDGKPLAPTGLPAETPAALLLPAGATGPAFLVFRNYDAIYAYNAAESYALSIALLAD
RLRGGAGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILAALRAA
PPVAGAAAMRATAFKLPAAYPAFAQSPSVQKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPEGGQD
VMWLSPSAQQPPTPIRGGAPVCWPYFGRQDQAGDVPAHGFVRTVAWQLTESHREDDGTVVLTLTPPRFDDLALRLRMTLR
IGRTLEQRLITENTSVAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYT
NAGGRYTLTDPVLGRRIVIATEGSRSLVAWNPGEDAGKKMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE

Sequences:

>Translated_720_residues
MTLSRGALPFVLGLLPLAACADPAFDRCLAGLQTQAAAKGVDAASFQRFTAGLAPDSSVLPLLDAQPEFTTPIWDYLASL
VDSQRVTDGQAMLVTHRELLSRLSDQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSL
LQQGDLSADGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
DASKAGRTRRQPLQAWQSAGLLGTDGKPLAPTGLPAETPAALLLPAGATGPAFLVFRNYDAIYAYNAAESYALSIALLAD
RLRGGAGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILAALRAA
PPVAGAAAMRATAFKLPAAYPAFAQSPSVQKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPEGGQD
VMWLSPSAQQPPTPIRGGAPVCWPYFGRQDQAGDVPAHGFVRTVAWQLTESHREDDGTVVLTLTPPRFDDLALRLRMTLR
IGRTLEQRLITENTSVAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYT
NAGGRYTLTDPVLGRRIVIATEGSRSLVAWNPGEDAGKKMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
>Mature_719_residues
TLSRGALPFVLGLLPLAACADPAFDRCLAGLQTQAAAKGVDAASFQRFTAGLAPDSSVLPLLDAQPEFTTPIWDYLASLV
DSQRVTDGQAMLVTHRELLSRLSDQTGVDPATIVAVWGVESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLL
QQGDLSADGLTGSWAGAFGQTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGFD
ASKAGRTRRQPLQAWQSAGLLGTDGKPLAPTGLPAETPAALLLPAGATGPAFLVFRNYDAIYAYNAAESYALSIALLADR
LRGGAGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGEADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILAALRAAP
PVAGAAAMRATAFKLPAAYPAFAQSPSVQKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPEGGQDV
MWLSPSAQQPPTPIRGGAPVCWPYFGRQDQAGDVPAHGFVRTVAWQLTESHREDDGTVVLTLTPPRFDDLALRLRMTLRI
GRTLEQRLITENTSVAPVRFTQALHNYFRVGDALKVSVQGLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTN
AGGRYTLTDPVLGRRIVIATEGSRSLVAWNPGEDAGKKMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE

Specific function: Unknown

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=280, Percent_Identity=34.6428571428571, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1789053, Length=249, Percent_Identity=33.7349397590361, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323746, Length=268, Percent_Identity=26.4925373134328, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19921284, Length=271, Percent_Identity=25.4612546125461, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 76992; Mature: 76861

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSRGALPFVLGLLPLAACADPAFDRCLAGLQTQAAAKGVDAASFQRFTAGLAPDSSVL
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PLLDAQPEFTTPIWDYLASLVDSQRVTDGQAMLVTHRELLSRLSDQTGVDPATIVAVWGV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEECC
ESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLLQQGDLSADGLTGSWAGAFG
CCCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCC
DASKAGRTRRQPLQAWQSAGLLGTDGKPLAPTGLPAETPAALLLPAGATGPAFLVFRNYD
CCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
AIYAYNAAESYALSIALLADRLRGGAGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGE
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
ADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILAALRAAPPVAGAAAMRATAFKLPAAY
CCCCCCHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PAFAQSPSVQKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPEGGQD
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCE
VMWLSPSAQQPPTPIRGGAPVCWPYFGRQDQAGDVPAHGFVRTVAWQLTESHREDDGTVV
EEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LTLTPPRFDDLALRLRMTLRIGRTLEQRLITENTSVAPVRFTQALHNYFRVGDALKVSVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
GLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTNAGGRYTLTDPVLGRRIVIA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEE
TEGSRSLVAWNPGEDAGKKMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
ECCCCEEEEECCCHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEECCCCCCCEEEEEECC
>Mature Secondary Structure 
TLSRGALPFVLGLLPLAACADPAFDRCLAGLQTQAAAKGVDAASFQRFTAGLAPDSSVL
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
PLLDAQPEFTTPIWDYLASLVDSQRVTDGQAMLVTHRELLSRLSDQTGVDPATIVAVWGV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEEEECC
ESDYGRVTGKRPLLVSLATLSCAGRRQPFFRGEFLALLSLLQQGDLSADGLTGSWAGAFG
CCCCCCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
QTQFMPSTYARIAVDGDGDGRRDLVTSIPDALASTANYLVKAGWERARPWGMEVTLPRGF
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCC
DASKAGRTRRQPLQAWQSAGLLGTDGKPLAPTGLPAETPAALLLPAGATGPAFLVFRNYD
CCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
AIYAYNAAESYALSIALLADRLRGGAGLIAAWPTDDPGLGRPERRELQQLLLARGYQIGE
EEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCC
ADGMVGSATRRAIQVEQTRLGLQPADGRPGQRILAALRAAPPVAGAAAMRATAFKLPAAY
CCCCCCHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
PAFAQSPSVQKASPMSDTTGLTTGDFHGFPSLLIDTPFSTAAISLFGGQLLSFVPEGGQD
CHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHCCCCCCE
VMWLSPSAQQPPTPIRGGAPVCWPYFGRQDQAGDVPAHGFVRTVAWQLTESHREDDGTVV
EEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LTLTPPRFDDLALRLRMTLRIGRTLEQRLITENTSVAPVRFTQALHNYFRVGDALKVSVQ
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
GLDGLDYLDKYENYATAHRQQGDWSLRDPRDPGRSDRIYTNAGGRYTLTDPVLGRRIVIA
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEE
TEGSRSLVAWNPGEDAGKKMADVGEGWRDYVCLEAANAGPDVIELAPGASHTLTQTISVE
ECCCCEEEEECCCHHHHHHHHHHCCCCHHEEEEEECCCCCCEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]