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The map label for this gene is piuB [H]

Identifier: 77748751

GI number: 77748751

Start: 4726366

End: 4728900

Strand: Reverse

Name: piuB [H]

Synonym: XAC4036

Alternate gene names: 77748751

Gene position: 4728900-4726366 (Counterclockwise)

Preceding gene: 21244755

Following gene: 21244751

Centisome position: 91.37

GC content: 67.18

Gene sequence:

>2535_bases
TTGATCAAGACGCTCCTGTTCCAGCTGCATTGGCTGCTCGGCATCACTGCCGGGCTGGTGCTGTCGGTGATGGGGTTGAC
CGGCGCGGCGATGTCGTTCGAAAACGAGATCGTGCGCATGGCCAATCCGGCCATTGCGCAACTGGCGCAGCGGCATGCGG
CGGGCGAGCGGGCCTTGCCGGTGGATGTGCTGCTGCAACGGCTCGATCTGGCGCCAGCCGGTGCGGGGCAAAAACAGGCG
GTGACGCGCCTGTTGATCGACCCCACCGGTGCGCGCCCGTCTGCCGCGCGTCTTTCCGGCAAGGGCGCGGGCCGGGTGTA
CTTCGACCCCTACACGGGTGAGCGGGTCGCGCCGCCGCGGCTGAGTACAGCGTTTGCCTTCATCGAAGACCTGCACCGCA
ACCTGACGGCCGGCAAACGCGGGCAGGCGGTCACCGGTGCGGGCGCCCTCATCTTGCTGTTCTTCTGCGCATCGGGGCTA
TATCTGCGCTGGCCGCGACGGTGGTGGAGCCCGCGCACCTGGTGGGTGGTGGAATGGCGACGGCAGGGGCGCAGTTTTTT
GTGGAGCCTGCATGCGGTGTTCGGCACCTGGTGCTTGCTGGTGTATTTGCTGGTCGCGCTGACCGGGCTGACCTGGTCCT
ACCCCTGGTATCGCGATGGCATGGTGGCCTTGCTCGGCGGCCCGCCTGCGATACGTGGCGACAAAGGCGATAGCCGCCCG
GCCACCGTCGATCTTGCACGCGTGCAGCGCACGCTCGATGGCATTCCCGCCACGCGCAGCGCCGCCCTGGATCTGCGCAT
TCCCACGCGCGCCGGGCAGCCGTTGAATGTGCGGTTCTTGCCCGACAATCCGGCTCACGATCGCGCCTACAACAGTCTTG
ATATCGCGCCGGACAGCGGAGCACTGCTGCAGCGCCAGGACTACGCGCTGCTGCCGCGCGGGCAGCAATTGGCGGTGAGC
ATGTTCCCGCTGCATTCGGGCAGTTTCTTCGGGTTGCCCGGGCGCATCGTGGTGATGCTGGCCAGCCTGGGCATGTCGGT
GTTCTTCGTCACCGGCTGGATGCTATATCTGGATCGGCGCCGCAAAAAACGTGCGCTGCGCGCGGCGCGCAAGGTGTTGC
AAGGCGCAGCACCGGCCTCGCAGGCGGCACCATGGTTGATTGCGTTTGCCAGCCAGAGCGGTTTTGCCGAGCGCCTGGCG
TGGCAGGCCGCCGGGCATCTGCAGGCTGCCGGCTTGCCGGTGCAGGTGCGCTCGCTGGCGCAGCTGGATGCACAGGCACT
GCAACGCACCGGGCATGCGTTGTTTGTGATCAGCACGTTTGGCGATGGCGAACCCCCGGATGCGGCACGCGGTTTCGAGC
GTGGGCTGCTGCGGCAACGCCTGGAATTGCCGCACCTGGCCTACGCGGTGCTGGCGCTGGGAGACCGCCAATACGCGCAG
TTCTGCGGGTTCTCGCGGCGTGTCGAACAGTGGCTGGATGCGCAAGGTGCACGCGCCCTGTTTCCTGCGGTGGAACTGGA
CAACGTCGACCCGCAGGCGCTGGCGCACTGGCATGCGCAGCTGGGCCAGATCGCCGGTGCACCCATGAACGTGGCGCCGC
TGGCACGCCCCAGATTGACCGAATGGACCCTGTCCTCGCGCACGCATCTGAATCCGGGCAGCCAGGGGGCGCCGATCTGG
CGTATCGATCTGCAGCCACCCGCCGATGCGCAGTGGCAGGCCGGCGACATCCTCGAAGTGCAGCCTGCGCATGCCCAGGC
GCAGGTGCGCACCTGTCTGGCGGCATGGGGCCTGGCGCCGGACGCACTGGTGCATGTGGATGCGCAGCTGCTGCCATTGC
AGCAGGCTGCCGCCGAGCGCGTACTGCCCGAGCCGCCCGCGATGCCGCTTGCCCATCGCCCTGATCCGCAAACCTGGCTG
GACGCATGCGCCTGGCTGCCCACACGCGATTATTCGCTCGCCAGCGTACCGGCTGACGCCACTGCGATGGTGGTGGTGCG
GCTGACGGCGCGTGCCGATGGCAGTCCCGGTCTGGGTTCGGGCTGGTTGATCTGCCACGCGGCGATCGGCGCGCCGGTGC
GCGCACGGTTGCGCACCAATCCCGGGTTCCATCGGCTCGAAACGATGCCGATGGTCTTGATCGGTAACGGCACCGGCATT
GCGGGCCTGCGCGCGCTGCTACGCGAGGCCGAGTTGGCCGGCGTGCATGGGCACTGGTTGTTGTTTGGCGAACGGCATGC
GGCGCACGACCGCCTGTTCGCCGACGAGCTGCAGGTCTGGCAGGCGAGTGGGCATCTACAGCAGCTGGAATGGGTGTTTT
CGCGCGATCAACCACAAAAACGCTACGTGCAGCATCACTTGCGCGACGCCGGCGACACGTTGCGACACTGGATCGACCGA
GGTGCGGTGATTTACGTCTGCGGCAGTCTGGACAGCATGGCGCGCGAGGTCGATGCGGCATTGCGCGAAGTACTCGGCGA
CACGCGTCTGGACTCATTGACCGCGGCGGGGCGTTATCGACGCGATGTGTACTGA

Upstream 100 bases:

>100_bases
GCGTGCAGCGGGACGCGGGCCGCCATCGGCATCGATGCAGATCGGATGCGAGACTCATTCTCATCTACAATGGCCGGCCG
TCCTGTTTCGTGGCCAGGTC

Downstream 100 bases:

>100_bases
GCGCGGCGATGACGGCACCAGCCCCGCTTTACATCGGCTAGCAGAACCTGGCGAGTGAGCACTGTGCGGGTGCGCAGAGT
GTAGAACCGCAGATCACCGT

Product: iron-uptake factor

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 844; Mature: 844

Protein sequence:

>844_residues
MIKTLLFQLHWLLGITAGLVLSVMGLTGAAMSFENEIVRMANPAIAQLAQRHAAGERALPVDVLLQRLDLAPAGAGQKQA
VTRLLIDPTGARPSAARLSGKGAGRVYFDPYTGERVAPPRLSTAFAFIEDLHRNLTAGKRGQAVTGAGALILLFFCASGL
YLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMVALLGGPPAIRGDKGDSRP
ATVDLARVQRTLDGIPATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVS
MFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKRALRAARKVLQGAAPASQAAPWLIAFASQSGFAERLA
WQAAGHLQAAGLPVQVRSLAQLDAQALQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLELPHLAYAVLALGDRQYAQ
FCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAHWHAQLGQIAGAPMNVAPLARPRLTEWTLSSRTHLNPGSQGAPIW
RIDLQPPADAQWQAGDILEVQPAHAQAQVRTCLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPAMPLAHRPDPQTWL
DACAWLPTRDYSLASVPADATAMVVVRLTARADGSPGLGSGWLICHAAIGAPVRARLRTNPGFHRLETMPMVLIGNGTGI
AGLRALLREAELAGVHGHWLLFGERHAAHDRLFADELQVWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDR
GAVIYVCGSLDSMAREVDAALREVLGDTRLDSLTAAGRYRRDVY

Sequences:

>Translated_844_residues
MIKTLLFQLHWLLGITAGLVLSVMGLTGAAMSFENEIVRMANPAIAQLAQRHAAGERALPVDVLLQRLDLAPAGAGQKQA
VTRLLIDPTGARPSAARLSGKGAGRVYFDPYTGERVAPPRLSTAFAFIEDLHRNLTAGKRGQAVTGAGALILLFFCASGL
YLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMVALLGGPPAIRGDKGDSRP
ATVDLARVQRTLDGIPATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVS
MFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKRALRAARKVLQGAAPASQAAPWLIAFASQSGFAERLA
WQAAGHLQAAGLPVQVRSLAQLDAQALQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLELPHLAYAVLALGDRQYAQ
FCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAHWHAQLGQIAGAPMNVAPLARPRLTEWTLSSRTHLNPGSQGAPIW
RIDLQPPADAQWQAGDILEVQPAHAQAQVRTCLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPAMPLAHRPDPQTWL
DACAWLPTRDYSLASVPADATAMVVVRLTARADGSPGLGSGWLICHAAIGAPVRARLRTNPGFHRLETMPMVLIGNGTGI
AGLRALLREAELAGVHGHWLLFGERHAAHDRLFADELQVWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDR
GAVIYVCGSLDSMAREVDAALREVLGDTRLDSLTAAGRYRRDVY
>Mature_844_residues
MIKTLLFQLHWLLGITAGLVLSVMGLTGAAMSFENEIVRMANPAIAQLAQRHAAGERALPVDVLLQRLDLAPAGAGQKQA
VTRLLIDPTGARPSAARLSGKGAGRVYFDPYTGERVAPPRLSTAFAFIEDLHRNLTAGKRGQAVTGAGALILLFFCASGL
YLRWPRRWWSPRTWWVVEWRRQGRSFLWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMVALLGGPPAIRGDKGDSRP
ATVDLARVQRTLDGIPATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSGALLQRQDYALLPRGQQLAVS
MFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRRRKKRALRAARKVLQGAAPASQAAPWLIAFASQSGFAERLA
WQAAGHLQAAGLPVQVRSLAQLDAQALQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLELPHLAYAVLALGDRQYAQ
FCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAHWHAQLGQIAGAPMNVAPLARPRLTEWTLSSRTHLNPGSQGAPIW
RIDLQPPADAQWQAGDILEVQPAHAQAQVRTCLAAWGLAPDALVHVDAQLLPLQQAAAERVLPEPPAMPLAHRPDPQTWL
DACAWLPTRDYSLASVPADATAMVVVRLTARADGSPGLGSGWLICHAAIGAPVRARLRTNPGFHRLETMPMVLIGNGTGI
AGLRALLREAELAGVHGHWLLFGERHAAHDRLFADELQVWQASGHLQQLEWVFSRDQPQKRYVQHHLRDAGDTLRHWIDR
GAVIYVCGSLDSMAREVDAALREVLGDTRLDSLTAAGRYRRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI221316709, Length=196, Percent_Identity=33.1632653061224, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI7657393, Length=202, Percent_Identity=33.1683168316832, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI221316705, Length=211, Percent_Identity=32.2274881516588, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI127139033, Length=232, Percent_Identity=28.8793103448276, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI169790956, Length=182, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI169790958, Length=182, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI221316707, Length=181, Percent_Identity=33.1491712707182, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789123, Length=540, Percent_Identity=28.8888888888889, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17554134, Length=225, Percent_Identity=31.5555555555556, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17566446, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321143, Length=237, Percent_Identity=25.3164556962025, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 92550; Mature: 92550

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTLLFQLHWLLGITAGLVLSVMGLTGAAMSFENEIVRMANPAIAQLAQRHAAGERALP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
VDVLLQRLDLAPAGAGQKQAVTRLLIDPTGARPSAARLSGKGAGRVYFDPYTGERVAPPR
HHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCC
LSTAFAFIEDLHRNLTAGKRGQAVTGAGALILLFFCASGLYLRWPRRWWSPRTWWVVEWR
HHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHCCCEEECCHHHCCCCCEEEEEHH
RQGRSFLWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMVALLGGPPAIRGDKGDSRP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
ATVDLARVQRTLDGIPATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSG
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
ALLQRQDYALLPRGQQLAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRR
CCEECCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKRALRAARKVLQGAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVRSLA
HHHHHHHHHHHHHHCCCCCHHCCCEEEEEECCCCHHHHHHHHHCCCCEECCCCHHHHHHH
QLDAQALQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLELPHLAYAVLALGDRQYAQ
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
FCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAHWHAQLGQIAGAPMNVAPLARPRLT
HCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EWTLSSRTHLNPGSQGAPIWRIDLQPPADAQWQAGDILEVQPAHAQAQVRTCLAAWGLAP
EEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
DALVHVDAQLLPLQQAAAERVLPEPPAMPLAHRPDPQTWLDACAWLPTRDYSLASVPADA
CHHEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TAMVVVRLTARADGSPGLGSGWLICHAAIGAPVRARLRTNPGFHRLETMPMVLIGNGTGI
EEEEEEEEEECCCCCCCCCCCCEEEEHHHCCCEEEEECCCCCCHHHCCCCEEEEECCCCH
AGLRALLREAELAGVHGHWLLFGERHAAHDRLFADELQVWQASGHLQQLEWVFSRDQPQK
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
RYVQHHLRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDAALREVLGDTRLDSLTAAGRYR
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
RDVY
CCCC
>Mature Secondary Structure
MIKTLLFQLHWLLGITAGLVLSVMGLTGAAMSFENEIVRMANPAIAQLAQRHAAGERALP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
VDVLLQRLDLAPAGAGQKQAVTRLLIDPTGARPSAARLSGKGAGRVYFDPYTGERVAPPR
HHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCC
LSTAFAFIEDLHRNLTAGKRGQAVTGAGALILLFFCASGLYLRWPRRWWSPRTWWVVEWR
HHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHCCCEEECCHHHCCCCCEEEEEHH
RQGRSFLWSLHAVFGTWCLLVYLLVALTGLTWSYPWYRDGMVALLGGPPAIRGDKGDSRP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCC
ATVDLARVQRTLDGIPATRSAALDLRIPTRAGQPLNVRFLPDNPAHDRAYNSLDIAPDSG
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
ALLQRQDYALLPRGQQLAVSMFPLHSGSFFGLPGRIVVMLASLGMSVFFVTGWMLYLDRR
CCEECCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKRALRAARKVLQGAAPASQAAPWLIAFASQSGFAERLAWQAAGHLQAAGLPVQVRSLA
HHHHHHHHHHHHHHCCCCCHHCCCEEEEEECCCCHHHHHHHHHCCCCEECCCCHHHHHHH
QLDAQALQRTGHALFVISTFGDGEPPDAARGFERGLLRQRLELPHLAYAVLALGDRQYAQ
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
FCGFSRRVEQWLDAQGARALFPAVELDNVDPQALAHWHAQLGQIAGAPMNVAPLARPRLT
HCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EWTLSSRTHLNPGSQGAPIWRIDLQPPADAQWQAGDILEVQPAHAQAQVRTCLAAWGLAP
EEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
DALVHVDAQLLPLQQAAAERVLPEPPAMPLAHRPDPQTWLDACAWLPTRDYSLASVPADA
CHHEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TAMVVVRLTARADGSPGLGSGWLICHAAIGAPVRARLRTNPGFHRLETMPMVLIGNGTGI
EEEEEEEEEECCCCCCCCCCCCEEEEHHHCCCEEEEECCCCCCHHHCCCCEEEEECCCCH
AGLRALLREAELAGVHGHWLLFGERHAAHDRLFADELQVWQASGHLQQLEWVFSRDQPQK
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
RYVQHHLRDAGDTLRHWIDRGAVIYVCGSLDSMAREVDAALREVLGDTRLDSLTAAGRYR
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
RDVY
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA