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The map label for this gene is dprE1 [H]

Identifier: 77748732

GI number: 77748732

Start: 4256640

End: 4257941

Strand: Direct

Name: dprE1 [H]

Synonym: XAC3590

Alternate gene names: 77748732

Gene position: 4256640-4257941 (Clockwise)

Preceding gene: 77748731

Following gene: 21244316

Centisome position: 82.25

GC content: 62.75

Gene sequence:

>1302_bases
ATGGCGCCGGGGCAATCCTGGGGGCGGTATCCCAGCGCGCAGCAGACGCTGCTACCGATCAACGATCGAGCGGCGAATCT
GCCCGCATTCGACGGCTTCGCGCTGCCTCGTGGTAACGGACGCAGTTATGGCGATAGTTGCCTGAATCCGGATGGCGCAC
TGCTGTGCGCACGCGGGCTTGATCGATTCATTACCTTTGATCCCGCCAATGGGGTCCTTCGCTGCGAAGCGGGGGTCACC
CTTGCCGAGATCATCGAGCTGGTGTTGCCGCAGGGCTGGTTTCTGCCGGTGACGCCCGGCACCCGCTACGTCACCGTTGC
CGGCGCCATTGCCAACGACGTGCATGGCAAGAACCACCATCGGACCGGCAATTTTGGTCACCATGTGCGCGCATTCGAGC
TGCTGCGTAGCGACGGCGAGCGCAGACTGTGCACGCCGGACGACGCCGATCGCTGGTTCGCAGCTACAGTGGGGGGACTT
GGGCTGACCGGCCTGATCACCTGGGCTGAAATTCAGCTGCGTCGCGTCGCCAGCTCCACGCTGGAAGCGGAAAACATCCG
CTTCGGCTCGCTCGATGAGTTTTTTGCGTTGTCGGCGGCCGCGGCCGAAAGCCACGAGTACAGCGTGGCGTGGATCGATT
GTCTGGCAAGCGGCAAGGCGCGCGGGCGCGGGCACTTTACCCGTGCAGATCACTGCACCGGGCTTGCGCATGAGCGACCG
AAATCGCCAGGTACAGGCTTATCCATGCCTGTCACCCCGCCGATTTCGTTGGTGAACACGTTCTCCCTGCGGCCTTTCAA
CGCGCTTTACTACTGGCGCCAGCCGGCGCCGCGCAAACGCTTCGTCAGCCACCTTTTGCCGTTCTTTTACCCGCTGGACG
GAATTCGTGACTGGAACCGCATGTACGGTCCTTCGGGCTTTCTGCAGTATCAATGCGTCTTGCCGCCCGCAACCGCGCGA
GACGGAGTGGACGCACTGCTTGCAGAGATCGCGCGCAGCGGCAGCGGCTCCTTCTTGGCCGTGTTGAAGGAATTCGGCAA
CACACCTTCCATTGGCATGCTGTCTTTCCCGAGGCCAGGCACGACCTTGGCATTGGACTTTCCCAATACCGGTCCTGGCG
TCTTCCGCCTGCTTGAGCGACTGGACCGCATCGTCGACGAGGCAGGCGGTGCTCTGTACCCTGCCAAGGACGCGCGTATG
ACAGCGCAGTCGTTTCAGCGTGCCTATGGCCGCTGGCGCGAGTTCGGCAGCTATCTCGATCCACGTTTTTCTTCCGGCTT
CTGGCGCCGGGTCACGGAGTAG

Upstream 100 bases:

>100_bases
GTGGAGAAATGCATGACGACCCGATCGTATTCGCTGCCACCGACCGCGTCAGTCAGATCGTGGTGGTGCTGTGCGGGTTA
TTCGCCCTGAGCGCCATCTG

Downstream 100 bases:

>100_bases
ACATGCAACGCGTCCTTATTATCGGGGCCACCTCGGCCATCGCCGAAGCAACCGCCCGACGCTACGCCGCACGCGGTGCG
GCCATCCACCTGCTCGGGCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MAPGQSWGRYPSAQQTLLPINDRAANLPAFDGFALPRGNGRSYGDSCLNPDGALLCARGLDRFITFDPANGVLRCEAGVT
LAEIIELVLPQGWFLPVTPGTRYVTVAGAIANDVHGKNHHRTGNFGHHVRAFELLRSDGERRLCTPDDADRWFAATVGGL
GLTGLITWAEIQLRRVASSTLEAENIRFGSLDEFFALSAAAAESHEYSVAWIDCLASGKARGRGHFTRADHCTGLAHERP
KSPGTGLSMPVTPPISLVNTFSLRPFNALYYWRQPAPRKRFVSHLLPFFYPLDGIRDWNRMYGPSGFLQYQCVLPPATAR
DGVDALLAEIARSGSGSFLAVLKEFGNTPSIGMLSFPRPGTTLALDFPNTGPGVFRLLERLDRIVDEAGGALYPAKDARM
TAQSFQRAYGRWREFGSYLDPRFSSGFWRRVTE

Sequences:

>Translated_433_residues
MAPGQSWGRYPSAQQTLLPINDRAANLPAFDGFALPRGNGRSYGDSCLNPDGALLCARGLDRFITFDPANGVLRCEAGVT
LAEIIELVLPQGWFLPVTPGTRYVTVAGAIANDVHGKNHHRTGNFGHHVRAFELLRSDGERRLCTPDDADRWFAATVGGL
GLTGLITWAEIQLRRVASSTLEAENIRFGSLDEFFALSAAAAESHEYSVAWIDCLASGKARGRGHFTRADHCTGLAHERP
KSPGTGLSMPVTPPISLVNTFSLRPFNALYYWRQPAPRKRFVSHLLPFFYPLDGIRDWNRMYGPSGFLQYQCVLPPATAR
DGVDALLAEIARSGSGSFLAVLKEFGNTPSIGMLSFPRPGTTLALDFPNTGPGVFRLLERLDRIVDEAGGALYPAKDARM
TAQSFQRAYGRWREFGSYLDPRFSSGFWRRVTE
>Mature_432_residues
APGQSWGRYPSAQQTLLPINDRAANLPAFDGFALPRGNGRSYGDSCLNPDGALLCARGLDRFITFDPANGVLRCEAGVTL
AEIIELVLPQGWFLPVTPGTRYVTVAGAIANDVHGKNHHRTGNFGHHVRAFELLRSDGERRLCTPDDADRWFAATVGGLG
LTGLITWAEIQLRRVASSTLEAENIRFGSLDEFFALSAAAAESHEYSVAWIDCLASGKARGRGHFTRADHCTGLAHERPK
SPGTGLSMPVTPPISLVNTFSLRPFNALYYWRQPAPRKRFVSHLLPFFYPLDGIRDWNRMYGPSGFLQYQCVLPPATARD
GVDALLAEIARSGSGSFLAVLKEFGNTPSIGMLSFPRPGTTLALDFPNTGPGVFRLLERLDRIVDEAGGALYPAKDARMT
AQSFQRAYGRWREFGSYLDPRFSSGFWRRVTE

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 47582; Mature: 47451

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPGQSWGRYPSAQQTLLPINDRAANLPAFDGFALPRGNGRSYGDSCLNPDGALLCARGL
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
DRFITFDPANGVLRCEAGVTLAEIIELVLPQGWFLPVTPGTRYVTVAGAIANDVHGKNHH
CCEEEECCCCCEEEECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECHHHHCCCCCCCC
RTGNFGHHVRAFELLRSDGERRLCTPDDADRWFAATVGGLGLTGLITWAEIQLRRVASST
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LEAENIRFGSLDEFFALSAAAAESHEYSVAWIDCLASGKARGRGHFTRADHCTGLAHERP
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEHEEHHHHCCCCCCCCCCCCCHHHCCCHHCCC
KSPGTGLSMPVTPPISLVNTFSLRPFNALYYWRQPAPRKRFVSHLLPFFYPLDGIRDWNR
CCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHH
MYGPSGFLQYQCVLPPATARDGVDALLAEIARSGSGSFLAVLKEFGNTPSIGMLSFPRPG
HCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCC
TTLALDFPNTGPGVFRLLERLDRIVDEAGGALYPAKDARMTAQSFQRAYGRWREFGSYLD
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PRFSSGFWRRVTE
CCCCCCHHHHCCC
>Mature Secondary Structure 
APGQSWGRYPSAQQTLLPINDRAANLPAFDGFALPRGNGRSYGDSCLNPDGALLCARGL
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
DRFITFDPANGVLRCEAGVTLAEIIELVLPQGWFLPVTPGTRYVTVAGAIANDVHGKNHH
CCEEEECCCCCEEEECCCCCHHHHHHHHCCCCCEEECCCCCEEEEEECHHHHCCCCCCCC
RTGNFGHHVRAFELLRSDGERRLCTPDDADRWFAATVGGLGLTGLITWAEIQLRRVASST
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LEAENIRFGSLDEFFALSAAAAESHEYSVAWIDCLASGKARGRGHFTRADHCTGLAHERP
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEHEEHHHHCCCCCCCCCCCCCHHHCCCHHCCC
KSPGTGLSMPVTPPISLVNTFSLRPFNALYYWRQPAPRKRFVSHLLPFFYPLDGIRDWNR
CCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHH
MYGPSGFLQYQCVLPPATARDGVDALLAEIARSGSGSFLAVLKEFGNTPSIGMLSFPRPG
HCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCC
TTLALDFPNTGPGVFRLLERLDRIVDEAGGALYPAKDARMTAQSFQRAYGRWREFGSYLD
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PRFSSGFWRRVTE
CCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]