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The map label for this gene is rutD [H]

Identifier: 77748689

GI number: 77748689

Start: 3553171

End: 3554166

Strand: Direct

Name: rutD [H]

Synonym: XAC3037

Alternate gene names: 77748689

Gene position: 3553171-3554166 (Clockwise)

Preceding gene: 21243763

Following gene: 77748691

Centisome position: 68.65

GC content: 61.75

Gene sequence:

>996_bases
ATGCGAAAGCGCGTTTGCACCCTCATGCTCGGCCTGGCCAGTAGTCCGCTACTGGCGCAGGAAGCCAGTTATGGCCCGCG
CCTGGAAGGCTTCGACTACCCACATCCAGTCAAGACTTATGCGTTCACCTCGCAACAGCAGCCGCTGGAAATGGCCTACC
TGGATGTTGCGCCAACCGGCACGCCCAATGGCCACACTGCGGTGCTGTTGCATGGCAAGAATTTCTGCGCCGCCACCTGG
GAAGACAGCATCGCAGCGCTAAGCAAGGCCGGCTACCGCGTCATCGCGCCAGACCAGATCGGTTTCTGCAAATCCAGCAA
GCCGGCCGCCTATCAGTTTTCGTTCGCGCAACTGGCAGACAATACGCATGCGTTGTTGAAGACGCTCGGCATCGAACGTG
CGGTGGTGGTCGGCCATTCGATGGGCGGCATGCTAGCCATTCGCTACGCGCTGATGTACCCGCAAGCCACCGAGCATCTG
GCGCTGGTGGACCCCATCGGGCTGGAAGACTGGAAGGCCGAAGGCATCCCCTGGCGCAGCGTGGACGCGTGGTACGACAA
CGAGATGAAAATCAGCTTCGAACGAATCAAGAAGTACCAGATGGACGTGTACTACGCCGGCCAATGGAAGCCGGAATTCG
AACGCTGGGCGCGCATGCAGGCCGGCATGTCGCTGGGCAAGGGCAAGCAGGCCGTGGCGTGGAATCAGGCGCTGACCTAC
GACATGGTCTTCAACCAGCCGGTGGTCTACGAGCTGCCCAAACTTGCGGTGCCGACCACGCTGTTCATCGGCCTCAAGGA
CCGCACCGCCATCGGCAAGGACACCGCACCGCCGCAGGTCAAGGCACGCGTGGGCGATTACACCAAGCTGGGCAAGCGCG
CGGCGGCCGCGATTCCGAATGCCAAACTGATCGAGTTTGCCGACCTGGGCCATTCGCCGCAGGTGCAGGACCCGGCGCGT
TTCAATGCTGCGCTGTTGAAGGCCATTGCGCAGTAA

Upstream 100 bases:

>100_bases
CAGCAACGCGCCTGCAGCGCCCGCTAACCGTCGCCCGGCTGTACGTTCCCACCACATCCGCCGTTGTACCGTCAGCGCCT
GGATTTGGATGGAGATCACC

Downstream 100 bases:

>100_bases
TGCTGTGGGTGGATGAGAGGGCAAGGATTGGACGCCCTCTCATCTTCACTGCGGCCGGTCGAAGCCGGCTGCAGCCAGCA
CCGATGGACAGACGGCGCCG

Product: hydrolase

Products: NA

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRKRVCTLMLGLASSPLLAQEASYGPRLEGFDYPHPVKTYAFTSQQQPLEMAYLDVAPTGTPNGHTAVLLHGKNFCAATW
EDSIAALSKAGYRVIAPDQIGFCKSSKPAAYQFSFAQLADNTHALLKTLGIERAVVVGHSMGGMLAIRYALMYPQATEHL
ALVDPIGLEDWKAEGIPWRSVDAWYDNEMKISFERIKKYQMDVYYAGQWKPEFERWARMQAGMSLGKGKQAVAWNQALTY
DMVFNQPVVYELPKLAVPTTLFIGLKDRTAIGKDTAPPQVKARVGDYTKLGKRAAAAIPNAKLIEFADLGHSPQVQDPAR
FNAALLKAIAQ

Sequences:

>Translated_331_residues
MRKRVCTLMLGLASSPLLAQEASYGPRLEGFDYPHPVKTYAFTSQQQPLEMAYLDVAPTGTPNGHTAVLLHGKNFCAATW
EDSIAALSKAGYRVIAPDQIGFCKSSKPAAYQFSFAQLADNTHALLKTLGIERAVVVGHSMGGMLAIRYALMYPQATEHL
ALVDPIGLEDWKAEGIPWRSVDAWYDNEMKISFERIKKYQMDVYYAGQWKPEFERWARMQAGMSLGKGKQAVAWNQALTY
DMVFNQPVVYELPKLAVPTTLFIGLKDRTAIGKDTAPPQVKARVGDYTKLGKRAAAAIPNAKLIEFADLGHSPQVQDPAR
FNAALLKAIAQ
>Mature_331_residues
MRKRVCTLMLGLASSPLLAQEASYGPRLEGFDYPHPVKTYAFTSQQQPLEMAYLDVAPTGTPNGHTAVLLHGKNFCAATW
EDSIAALSKAGYRVIAPDQIGFCKSSKPAAYQFSFAQLADNTHALLKTLGIERAVVVGHSMGGMLAIRYALMYPQATEHL
ALVDPIGLEDWKAEGIPWRSVDAWYDNEMKISFERIKKYQMDVYYAGQWKPEFERWARMQAGMSLGKGKQAVAWNQALTY
DMVFNQPVVYELPKLAVPTTLFIGLKDRTAIGKDTAPPQVKARVGDYTKLGKRAAAAIPNAKLIEFADLGHSPQVQDPAR
FNAALLKAIAQ

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Drosophila melanogaster, GI24586387, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24586391, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24586389, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24586385, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 36557; Mature: 36557

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRVCTLMLGLASSPLLAQEASYGPRLEGFDYPHPVKTYAFTSQQQPLEMAYLDVAPTG
CCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCC
TPNGHTAVLLHGKNFCAATWEDSIAALSKAGYRVIAPDQIGFCKSSKPAAYQFSFAQLAD
CCCCCEEEEEECCCEEEECCHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEHHHHHCC
NTHALLKTLGIERAVVVGHSMGGMLAIRYALMYPQATEHLALVDPIGLEDWKAEGIPWRS
CHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
VDAWYDNEMKISFERIKKYQMDVYYAGQWKPEFERWARMQAGMSLGKGKQAVAWNQALTY
CCCCCCCCEEEEHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEE
DMVFNQPVVYELPKLAVPTTLFIGLKDRTAIGKDTAPPQVKARVGDYTKLGKRAAAAIPN
EEEECCCHHEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC
AKLIEFADLGHSPQVQDPARFNAALLKAIAQ
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRKRVCTLMLGLASSPLLAQEASYGPRLEGFDYPHPVKTYAFTSQQQPLEMAYLDVAPTG
CCCHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCC
TPNGHTAVLLHGKNFCAATWEDSIAALSKAGYRVIAPDQIGFCKSSKPAAYQFSFAQLAD
CCCCCEEEEEECCCEEEECCHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEHHHHHCC
NTHALLKTLGIERAVVVGHSMGGMLAIRYALMYPQATEHLALVDPIGLEDWKAEGIPWRS
CHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
VDAWYDNEMKISFERIKKYQMDVYYAGQWKPEFERWARMQAGMSLGKGKQAVAWNQALTY
CCCCCCCCEEEEHHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCEEE
DMVFNQPVVYELPKLAVPTTLFIGLKDRTAIGKDTAPPQVKARVGDYTKLGKRAAAAIPN
EEEECCCHHEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCC
AKLIEFADLGHSPQVQDPARFNAALLKAIAQ
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA