BacMap

Definition	Rhodobacter sphaeroides 2.4.1 chromosome 2, complete sequence.
Accession	NC_007494
Length	943,016

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The map label for this gene is rbtD [H]

Identifier: 77465712

GI number: 77465712

Start: 825464

End: 826192

Strand: Direct

Name: rbtD [H]

Synonym: RSP_3704

Alternate gene names: 77465712

Gene position: 825464-826192 (Clockwise)

Preceding gene: 77465711

Following gene: 77465713

Centisome position: 87.53

GC content: 69.0

Gene sequence:

>729_bases
ATGGCAGAGCTCATGCAAGGAAAGGTGGCCGCCATCACCGGCGCGGCCTCGGGAATCGGGCTGGAATGCGCGCGCACCCT
CGTGGCCGAAGGCGCCACGGTGGTGCTGATCGACCGCGCCGAGGACCGGCTCAAGGCGCTCTGCGCCGAGATCGGGCCGC
GCGCCCTGCCGCTCGTCGTCGATCTGCTCGACGGGCCGCAGGTCTCGGGGATGCTGCCGCGCATTCTCGAGCTGGCGGGC
TCGCTCGACATCTTTCACGCCAATGCGGGCGCCTATATCGGCGGGCAGGTGGCCGAGGGCGATCCCGACGCCTGGGACCG
GATGCTGAACCTCAACATCAACGCGGCCTTCCGCTCGGTCCATGCCGTCCTGCCCTACATGATAGAGCGGAAGAGCGGTG
ACATCCTCTTCACGAGCTCGGTCGCGGGCGTGGTGCCGGTGGTCTGGGAGCCGATCTACACCGCCTCGAAATTCGCGGTG
CAGGCCTTCGTCCATTCCACCCGCCGTCAGGTCGCGCCGCACGGCGTGCGCGTGGGCGCGGTGCTGCCCGGCCCGGTGGT
GACGGCGCTCCTCGACGACTGGCCCAAGGCCAAGATGGAGGAGGCGCTGGCCAACGGCTCGCTCATGCAGCCGAAGGAAG
TGGCCGAGGCCGTGCTCTTCATGCTCTCGCGCCCGAAGGGCGTCGTGATCCGCGACCTCGTGATCCTGCCGCACAGCGTC
GACATCTGA

Upstream 100 bases:

>100_bases
CTACATGATCACCGGCGGCGTGCTGGCCATTGCCGTCATCGTGGACTCGCTCGCCCGCCAGAGCCGGGTCAGCCACGGAC
GCGCCTAGAAAGGACCCATC

Downstream 100 bases:

>100_bases
CCCGCGCTTCCGGGCGGCCCCCTTCGGCGGGGCGCCGCCCGGCCCCGGCGCGCCTTCCGCGAAAGGCCCCTCCATGACCC
AGGATCCCTCCCGTCCCGCG

Product: ribitol 2-dehydrogenase

Products: NA

Alternate protein names: RDH [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAELMQGKVAAITGAASGIGLECARTLVAEGATVVLIDRAEDRLKALCAEIGPRALPLVVDLLDGPQVSGMLPRILELAG
SLDIFHANAGAYIGGQVAEGDPDAWDRMLNLNINAAFRSVHAVLPYMIERKSGDILFTSSVAGVVPVVWEPIYTASKFAV
QAFVHSTRRQVAPHGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPKEVAEAVLFMLSRPKGVVIRDLVILPHSV
DI

Sequences:

>Translated_242_residues
MAELMQGKVAAITGAASGIGLECARTLVAEGATVVLIDRAEDRLKALCAEIGPRALPLVVDLLDGPQVSGMLPRILELAG
SLDIFHANAGAYIGGQVAEGDPDAWDRMLNLNINAAFRSVHAVLPYMIERKSGDILFTSSVAGVVPVVWEPIYTASKFAV
QAFVHSTRRQVAPHGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPKEVAEAVLFMLSRPKGVVIRDLVILPHSV
DI
>Mature_241_residues
AELMQGKVAAITGAASGIGLECARTLVAEGATVVLIDRAEDRLKALCAEIGPRALPLVVDLLDGPQVSGMLPRILELAGS
LDIFHANAGAYIGGQVAEGDPDAWDRMLNLNINAAFRSVHAVLPYMIERKSGDILFTSSVAGVVPVVWEPIYTASKFAVQ
AFVHSTRRQVAPHGVRVGAVLPGPVVTALLDDWPKAKMEEALANGSLMQPKEVAEAVLFMLSRPKGVVIRDLVILPHSVD
I

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=246, Percent_Identity=30.0813008130081, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.6732673267327, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7706318, Length=223, Percent_Identity=29.5964125560538, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=25.7261410788382, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503817, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=32.3529411764706, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI157739938, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=28.0769230769231, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40254992, Length=218, Percent_Identity=24.7706422018349, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=252, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI66933014, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI59889578, Length=210, Percent_Identity=29.5238095238095, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=31.3829787234043, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=220, Percent_Identity=25.9090909090909, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI126723750, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=237, Percent_Identity=24.4725738396624, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32455239, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI5031765, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082100, Length=234, Percent_Identity=32.9059829059829, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=29.0598290598291, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=26.3440860215054, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=226, Percent_Identity=32.3008849557522, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789208, Length=187, Percent_Identity=29.9465240641711, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786701, Length=239, Percent_Identity=26.7782426778243, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787905, Length=233, Percent_Identity=28.3261802575107, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788459, Length=193, Percent_Identity=27.4611398963731, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=26.3374485596708, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=26.0504201680672, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=31.0204081632653, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=242, Percent_Identity=30.9917355371901, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=241, Percent_Identity=28.2157676348548, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=242, Percent_Identity=29.7520661157025, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=27.8008298755187, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=246, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=248, Percent_Identity=28.6290322580645, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=241, Percent_Identity=29.045643153527, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=250, Percent_Identity=29.6, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=232, Percent_Identity=26.2931034482759, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=230, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=243, Percent_Identity=27.9835390946502, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=241, Percent_Identity=27.8008298755187, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=243, Percent_Identity=27.9835390946502, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=245, Percent_Identity=26.9387755102041, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=248, Percent_Identity=26.2096774193548, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=26.5822784810127, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=23.9043824701195, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=248, Percent_Identity=27.0161290322581, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=26.8482490272374, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=26.8041237113402, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=256, Percent_Identity=31.640625, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=240, Percent_Identity=30.4166666666667, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=201, Percent_Identity=28.8557213930348, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357041, Length=232, Percent_Identity=31.8965517241379, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28571387, Length=233, Percent_Identity=33.0472103004292, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=32.3144104803493, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571526, Length=232, Percent_Identity=31.4655172413793, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21358495, Length=241, Percent_Identity=30.7053941908714, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=28.4, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24644339, Length=230, Percent_Identity=31.7391304347826, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641232, Length=251, Percent_Identity=29.4820717131474, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24639444, Length=227, Percent_Identity=29.0748898678414, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007236, Length=246, Percent_Identity=28.4552845528455, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24663911, Length=246, Percent_Identity=28.4552845528455, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364494, Length=253, Percent_Identity=28.4584980237154, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24643142, Length=230, Percent_Identity=28.695652173913, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364892, Length=224, Percent_Identity=27.6785714285714, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=29.9492385786802, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648944, Length=239, Percent_Identity=26.7782426778243, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=29.9492385786802, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=248, Percent_Identity=28.2258064516129, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644337, Length=232, Percent_Identity=31.8965517241379, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=28.4883720930233, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640492, Length=196, Percent_Identity=27.0408163265306, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007238, Length=196, Percent_Identity=27.0408163265306, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=26.4864864864865, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356301, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648693, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355889, Length=244, Percent_Identity=26.6393442622951, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737361, Length=247, Percent_Identity=25.9109311740891, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=25.6, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.56 [H]

Molecular weight: Translated: 25671; Mature: 25540

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELMQGKVAAITGAASGIGLECARTLVAEGATVVLIDRAEDRLKALCAEIGPRALPLVV
CCCHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHHE
DLLDGPQVSGMLPRILELAGSLDIFHANAGAYIGGQVAEGDPDAWDRMLNLNINAAFRSV
ECCCCCCCCCHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHEEECCHHHHHHHH
HAVLPYMIERKSGDILFTSSVAGVVPVVWEPIYTASKFAVQAFVHSTRRQVAPHGVRVGA
HHHHHHHHHCCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VLPGPVVTALLDDWPKAKMEEALANGSLMQPKEVAEAVLFMLSRPKGVVIRDLVILPHSV
ECCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
DI
CC
>Mature Secondary Structure 
AELMQGKVAAITGAASGIGLECARTLVAEGATVVLIDRAEDRLKALCAEIGPRALPLVV
CCHHCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCHHHHHE
DLLDGPQVSGMLPRILELAGSLDIFHANAGAYIGGQVAEGDPDAWDRMLNLNINAAFRSV
ECCCCCCCCCHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHEEECCHHHHHHHH
HAVLPYMIERKSGDILFTSSVAGVVPVVWEPIYTASKFAVQAFVHSTRRQVAPHGVRVGA
HHHHHHHHHCCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VLPGPVVTALLDDWPKAKMEEALANGSLMQPKEVAEAVLFMLSRPKGVVIRDLVILPHSV
ECCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
DI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3904726; 2933028; 3891331 [H]