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The map label for this gene is xylH [H]

Identifier: 77465711

GI number: 77465711

Start: 824204

End: 825451

Strand: Direct

Name: xylH [H]

Synonym: RSP_3703

Alternate gene names: 77465711

Gene position: 824204-825451 (Clockwise)

Preceding gene: 77465710

Following gene: 77465712

Centisome position: 87.4

GC content: 68.67

Gene sequence:

>1248_bases
GTGACCATGGATCCGAAACCAGAGGCGCTCGACCGCGGCGACAGCCGCCTGCGCCACGACGAGGGGCTTCTCGGCGCCGC
GCGCGCCTTCTTCGACCGCGTGCGCTCGGGCGATCTCGGCATGCTGCCGGTGCTCGTGGGGCTCGTGGTGATCTCGACCG
TCTTCTCGACGCTGAACCCGGTGTTCCTCGCGCCGAACAACCTCGTGAACCTGCTCTTCGACGCGGCCACGGTGGGCTTC
ATCTCGCTCGGCATCGTCTGCGTGCTGATGCTGGGCCAGATCGACCTCTCCGTGGGCTCGATGAGCGGCCTCGCCTCGGC
GATGATCGGGGTGCTCTGGGTCAACATGGGCTGGCCGCTGCCCGCGGCCATCGCGGTGGCGCTCGGCTTCGGGGCGCTGG
TGGGGCTGATCTACAGCGTGCTCCTCAACCGCTTCAAGATGCCGAGCTACGAATCGACCCTACGACAGGGCCTACTCGCG
CTCCTGGGGCTGCAGCTCTACATCCTCGGGCCCACCGGCTCGATCAACCTGCCCTATGCCTCGGTGCTGGTGCGGTTCGG
GCAGATCTATGTCATGCCGGACTGGCTCTCCTACCTCTTGGCGCTGCTGCCGGGGGCGATCCTTGTCTTTACGGGGCTGC
GCACCATGGCGCGCCGGCGGGCAGCCAACCTCTCCTCGCCGGGGCTGAGCGTCCTTCTCGTCAAGGCGCTCGTCCTGACC
GCAGCGCTTCTCTACGCGGCCTATTACCTGAACCTCGGCCGCGGCATCCCGTGGATGTTCGGCCTGTTCGTGGCGCTCGT
GCTGGCGATGAACTACGGGCTGACGCGCACCCAATGGGGCCGCTCGATGTTCGCCGTGGGCGGCAATGCCGAGGCCGCGC
GCCGGTCCGGCATCGATGTGCGCCGGGTCAATGTCTCGGCCTTCATGCTCTGCTCGACGCTGGCGGCCCTCGGCGGCATC
CTCGCCTCGGCCCGGCTCGCCTCCTCGAGCCAGCAGGCCGGCACCGGCGACGTGAACCTCAATGCCATCGCCGCGGCCGT
GATCGGCGGCACCAGCCTCTTCGGCGGCCGGGGCAGCGCCTATTCCGCCCTGCTCGGGATCCTCGTCATCCAGGCGATCT
CGAACGGCCTCACGCTTCTCAACCTCAGCTCGTCGCTCCGCTACATGATCACCGGCGGCGTGCTGGCCATTGCCGTCATC
GTGGACTCGCTCGCCCGCCAGAGCCGGGTCAGCCACGGACGCGCCTAG

Upstream 100 bases:

>100_bases
CCGCCGACACGTCGAACAACGAGCTTGTCGCCGCCATCACCGGCGCGACCGAGAACTCCGTCTCGCGCCGTCAGGCCCGC
AAGCAGCAGGAGGCCCAGGA

Downstream 100 bases:

>100_bases
AAAGGACCCATCATGGCAGAGCTCATGCAAGGAAAGGTGGCCGCCATCACCGGCGCGGCCTCGGGAATCGGGCTGGAATG
CGCGCGCACCCTCGTGGCCG

Product: ABC sugar transporter, inner membrane subunit

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTMDPKPEALDRGDSRLRHDEGLLGAARAFFDRVRSGDLGMLPVLVGLVVISTVFSTLNPVFLAPNNLVNLLFDAATVGF
ISLGIVCVLMLGQIDLSVGSMSGLASAMIGVLWVNMGWPLPAAIAVALGFGALVGLIYSVLLNRFKMPSYESTLRQGLLA
LLGLQLYILGPTGSINLPYASVLVRFGQIYVMPDWLSYLLALLPGAILVFTGLRTMARRRAANLSSPGLSVLLVKALVLT
AALLYAAYYLNLGRGIPWMFGLFVALVLAMNYGLTRTQWGRSMFAVGGNAEAARRSGIDVRRVNVSAFMLCSTLAALGGI
LASARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGILVIQAISNGLTLLNLSSSLRYMITGGVLAIAVI
VDSLARQSRVSHGRA

Sequences:

>Translated_415_residues
MTMDPKPEALDRGDSRLRHDEGLLGAARAFFDRVRSGDLGMLPVLVGLVVISTVFSTLNPVFLAPNNLVNLLFDAATVGF
ISLGIVCVLMLGQIDLSVGSMSGLASAMIGVLWVNMGWPLPAAIAVALGFGALVGLIYSVLLNRFKMPSYESTLRQGLLA
LLGLQLYILGPTGSINLPYASVLVRFGQIYVMPDWLSYLLALLPGAILVFTGLRTMARRRAANLSSPGLSVLLVKALVLT
AALLYAAYYLNLGRGIPWMFGLFVALVLAMNYGLTRTQWGRSMFAVGGNAEAARRSGIDVRRVNVSAFMLCSTLAALGGI
LASARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGILVIQAISNGLTLLNLSSSLRYMITGGVLAIAVI
VDSLARQSRVSHGRA
>Mature_414_residues
TMDPKPEALDRGDSRLRHDEGLLGAARAFFDRVRSGDLGMLPVLVGLVVISTVFSTLNPVFLAPNNLVNLLFDAATVGFI
SLGIVCVLMLGQIDLSVGSMSGLASAMIGVLWVNMGWPLPAAIAVALGFGALVGLIYSVLLNRFKMPSYESTLRQGLLAL
LGLQLYILGPTGSINLPYASVLVRFGQIYVMPDWLSYLLALLPGAILVFTGLRTMARRRAANLSSPGLSVLLVKALVLTA
ALLYAAYYLNLGRGIPWMFGLFVALVLAMNYGLTRTQWGRSMFAVGGNAEAARRSGIDVRRVNVSAFMLCSTLAALGGIL
ASARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGILVIQAISNGLTLLNLSSSLRYMITGGVLAIAVIV
DSLARQSRVSHGRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=380, Percent_Identity=33.6842105263158, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788896, Length=388, Percent_Identity=32.7319587628866, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790191, Length=160, Percent_Identity=41.875, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790524, Length=156, Percent_Identity=38.4615384615385, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693152, Length=168, Percent_Identity=34.5238095238095, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082395, Length=331, Percent_Identity=29.607250755287, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43594; Mature: 43463

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDPKPEALDRGDSRLRHDEGLLGAARAFFDRVRSGDLGMLPVLVGLVVISTVFSTLNP
CCCCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
VFLAPNNLVNLLFDAATVGFISLGIVCVLMLGQIDLSVGSMSGLASAMIGVLWVNMGWPL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
PAAIAVALGFGALVGLIYSVLLNRFKMPSYESTLRQGLLALLGLQLYILGPTGSINLPYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
SVLVRFGQIYVMPDWLSYLLALLPGAILVFTGLRTMARRRAANLSSPGLSVLLVKALVLT
HHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AALLYAAYYLNLGRGIPWMFGLFVALVLAMNYGLTRTQWGRSMFAVGGNAEAARRSGIDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEECCCCHHHHHCCCCE
RRVNVSAFMLCSTLAALGGILASARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSA
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHH
YSALLGILVIQAISNGLTLLNLSSSLRYMITGGVLAIAVIVDSLARQSRVSHGRA
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMDPKPEALDRGDSRLRHDEGLLGAARAFFDRVRSGDLGMLPVLVGLVVISTVFSTLNP
CCCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
VFLAPNNLVNLLFDAATVGFISLGIVCVLMLGQIDLSVGSMSGLASAMIGVLWVNMGWPL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCH
PAAIAVALGFGALVGLIYSVLLNRFKMPSYESTLRQGLLALLGLQLYILGPTGSINLPYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
SVLVRFGQIYVMPDWLSYLLALLPGAILVFTGLRTMARRRAANLSSPGLSVLLVKALVLT
HHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AALLYAAYYLNLGRGIPWMFGLFVALVLAMNYGLTRTQWGRSMFAVGGNAEAARRSGIDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEECCCCHHHHHCCCCE
RRVNVSAFMLCSTLAALGGILASARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSA
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHH
YSALLGILVIQAISNGLTLLNLSSSLRYMITGGVLAIAVIVDSLARQSRVSHGRA
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]