Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 77465593

GI number: 77465593

Start: 684191

End: 685528

Strand: Reverse

Name: aroA [H]

Synonym: RSP_3592

Alternate gene names: 77465593

Gene position: 685528-684191 (Counterclockwise)

Preceding gene: 77465594

Following gene: 77465592

Centisome position: 72.7

GC content: 71.6

Gene sequence:

>1338_bases
ATGTCCGGACACGGGCCCGCGCAACCGATGACCGCTCGCCGCTCGGGGCCGCTGAAGGGGCGTGCCGAGATCCCCGGCGA
CAAGTCGATCAGCCACCGCGCGCTGATCCTCGGCGCCATGGCGGTGGGCGAGACGCGGATCACGGGTCTTCTCGAGGGGC
AGGACGTGCTCGACACCGCGAAGGCCATGCGCGCCTTCGGCGCCGAGGTGATCCAGCACGGGCCGGGCGCCTGGTCGGTG
CATGGGGTGGGCGTGGGGGGCTTCACCGAGCCCGCCGAGGTGATCGACTGCGGCAATTCCGGCACCGGCGTGCGGCTGGT
GATGGGGGCGATGGCTACCTCGCCGCTGACCGCGACCTTCACCGGCGATGCCTCGCTCCGCAAGCGGCCCATGGGGCGGG
TGACCGATCCGCTGGCTCTGTTCGGCACGCGCGCCTACGGGCGCAAGGGCGGGCGGCTGCCGATGACGCTCGTGGGCGCC
GCCGATCCGGTGCCGGTGCGCTATACGGTGCCGGTGCCCTCGGCGCAGGTGAAATCGGCGGTTCTTCTGGCCGGGCTGAA
CGCGCCCGGGCAGACGGTCGTGATCGAGCGCGAGGCGACGCGGGACCATTCCGAGCGGATGCTGCGCGGCTTCGGCGCCG
AACTCAGCGTCGAGACGGGGCCCGAGGGGCAGGTCATCACCCTGACCGGGCAGCCGGAGCTTCGGCCGCAGACGGTGGCG
GTTCCGCGCGATCCGTCCTCGGCGGCCTTTCCGGTCTGCGCGGCGCTGATCGTCGAGGGATCCGAGATCCTGGTGCCGGG
GGTGAGCCGCAATCCCACCCGGGACGGGCTCTATGTGACGCTGCTCGAGATGGGCGCAGACATCGCCTTCGAGAACGAGC
GCGAGGAGGGCGGCGAGCCGGTGGCCGACCTGCGCGTGCGGGCCTCGGCCCTCAAGGGCGTGGAGGTGCCGCCCGAGCGC
GCGCCCTCGATGATCGACGAATATCCGATCCTGTCGGTGGTGGCGGCCTTTGCCGAGGGCTTGACGATCATGCGCGGCGT
GAAGGAGCTGCGCGTGAAGGAGAGCGACCGGATCGACGCGATGGCGCGGGGGCTTGAGGCCTGCGGCGTGCGGATCGAGG
AGGACGAGGATACGCTGATCGTCCATGGCATGGGCCGGGTGCCGGGCGGGGCCACCTGCGCCACCCATCTCGATCACCGG
ATCGCCATGAGCTTCCTCGTGCTCGGCATGGCGGCGGAGGCGCCGGTGACCGTCGACGACGGCTCGCCTATCGCGACCTC
CTTCCCTGCCTTCATCGATCTGATGGCGGGTCTCGGAGCGGATCTGGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
TTGTGTCGTCGGGTGGTGCGCGGTGCCTGCGGGCGGGTTTGATGCTGGACCGGACCGGGCGCATTGGGTAAGGCTCGCGC
CGTCAATCTGGAGGAAGATC

Downstream 100 bases:

>100_bases
GCAGGCGGCGGCGGGGGCTTCGCGCCCCCGCACCCCCGCGGGATATTTGGACCAGAATGAAAGGCCGGGGAATGCGCTTC
ACGGTGGCGATCGACGGGCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSGHGPAQPMTARRSGPLKGRAEIPGDKSISHRALILGAMAVGETRITGLLEGQDVLDTAKAMRAFGAEVIQHGPGAWSV
HGVGVGGFTEPAEVIDCGNSGTGVRLVMGAMATSPLTATFTGDASLRKRPMGRVTDPLALFGTRAYGRKGGRLPMTLVGA
ADPVPVRYTVPVPSAQVKSAVLLAGLNAPGQTVVIEREATRDHSERMLRGFGAELSVETGPEGQVITLTGQPELRPQTVA
VPRDPSSAAFPVCAALIVEGSEILVPGVSRNPTRDGLYVTLLEMGADIAFENEREEGGEPVADLRVRASALKGVEVPPER
APSMIDEYPILSVVAAFAEGLTIMRGVKELRVKESDRIDAMARGLEACGVRIEEDEDTLIVHGMGRVPGGATCATHLDHR
IAMSFLVLGMAAEAPVTVDDGSPIATSFPAFIDLMAGLGADLAAG

Sequences:

>Translated_445_residues
MSGHGPAQPMTARRSGPLKGRAEIPGDKSISHRALILGAMAVGETRITGLLEGQDVLDTAKAMRAFGAEVIQHGPGAWSV
HGVGVGGFTEPAEVIDCGNSGTGVRLVMGAMATSPLTATFTGDASLRKRPMGRVTDPLALFGTRAYGRKGGRLPMTLVGA
ADPVPVRYTVPVPSAQVKSAVLLAGLNAPGQTVVIEREATRDHSERMLRGFGAELSVETGPEGQVITLTGQPELRPQTVA
VPRDPSSAAFPVCAALIVEGSEILVPGVSRNPTRDGLYVTLLEMGADIAFENEREEGGEPVADLRVRASALKGVEVPPER
APSMIDEYPILSVVAAFAEGLTIMRGVKELRVKESDRIDAMARGLEACGVRIEEDEDTLIVHGMGRVPGGATCATHLDHR
IAMSFLVLGMAAEAPVTVDDGSPIATSFPAFIDLMAGLGADLAAG
>Mature_444_residues
SGHGPAQPMTARRSGPLKGRAEIPGDKSISHRALILGAMAVGETRITGLLEGQDVLDTAKAMRAFGAEVIQHGPGAWSVH
GVGVGGFTEPAEVIDCGNSGTGVRLVMGAMATSPLTATFTGDASLRKRPMGRVTDPLALFGTRAYGRKGGRLPMTLVGAA
DPVPVRYTVPVPSAQVKSAVLLAGLNAPGQTVVIEREATRDHSERMLRGFGAELSVETGPEGQVITLTGQPELRPQTVAV
PRDPSSAAFPVCAALIVEGSEILVPGVSRNPTRDGLYVTLLEMGADIAFENEREEGGEPVADLRVRASALKGVEVPPERA
PSMIDEYPILSVVAAFAEGLTIMRGVKELRVKESDRIDAMARGLEACGVRIEEDEDTLIVHGMGRVPGGATCATHLDHRI
AMSFLVLGMAAEAPVTVDDGSPIATSFPAFIDLMAGLGADLAAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=429, Percent_Identity=29.8368298368298, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=473, Percent_Identity=27.906976744186, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46328; Mature: 46197

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGHGPAQPMTARRSGPLKGRAEIPGDKSISHRALILGAMAVGETRITGLLEGQDVLDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHEEEEECCCHHHHHH
KAMRAFGAEVIQHGPGAWSVHGVGVGGFTEPAEVIDCGNSGTGVRLVMGAMATSPLTATF
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHEECCCCCCCCEEEEHHHCCCCEEEEE
TGDASLRKRPMGRVTDPLALFGTRAYGRKGGRLPMTLVGAADPVPVRYTVPVPSAQVKSA
ECCHHHHHCCCCCCCCCHHHHHCHHHCCCCCCCCEEEECCCCCCCEEEECCCCCHHHCCE
VLLAGLNAPGQTVVIEREATRDHSERMLRGFGAELSVETGPEGQVITLTGQPELRPQTVA
EEEEECCCCCCEEEEECHHCCCHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCCEEE
VPRDPSSAAFPVCAALIVEGSEILVPGVSRNPTRDGLYVTLLEMGADIAFENEREEGGEP
CCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEHHCCCEEECCCHHHCCCC
VADLRVRASALKGVEVPPERAPSMIDEYPILSVVAAFAEGLTIMRGVKELRVKESDRIDA
HHHHHHHHHHHCCCCCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MARGLEACGVRIEEDEDTLIVHGMGRVPGGATCATHLDHRIAMSFLVLGMAAEAPVTVDD
HHHHHHHHCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GSPIATSFPAFIDLMAGLGADLAAG
CCCCHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SGHGPAQPMTARRSGPLKGRAEIPGDKSISHRALILGAMAVGETRITGLLEGQDVLDTA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCHHEEEEECCCHHHHHH
KAMRAFGAEVIQHGPGAWSVHGVGVGGFTEPAEVIDCGNSGTGVRLVMGAMATSPLTATF
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHEECCCCCCCCEEEEHHHCCCCEEEEE
TGDASLRKRPMGRVTDPLALFGTRAYGRKGGRLPMTLVGAADPVPVRYTVPVPSAQVKSA
ECCHHHHHCCCCCCCCCHHHHHCHHHCCCCCCCCEEEECCCCCCCEEEECCCCCHHHCCE
VLLAGLNAPGQTVVIEREATRDHSERMLRGFGAELSVETGPEGQVITLTGQPELRPQTVA
EEEEECCCCCCEEEEECHHCCCHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCCCEEE
VPRDPSSAAFPVCAALIVEGSEILVPGVSRNPTRDGLYVTLLEMGADIAFENEREEGGEP
CCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEEHHCCCEEECCCHHHCCCC
VADLRVRASALKGVEVPPERAPSMIDEYPILSVVAAFAEGLTIMRGVKELRVKESDRIDA
HHHHHHHHHHHCCCCCCHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MARGLEACGVRIEEDEDTLIVHGMGRVPGGATCATHLDHRIAMSFLVLGMAAEAPVTVDD
HHHHHHHHCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GSPIATSFPAFIDLMAGLGADLAAG
CCCCHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA