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The map label for this gene is hisZ [H]

Identifier: 77465549

GI number: 77465549

Start: 639999

End: 641096

Strand: Reverse

Name: hisZ [H]

Synonym: RSP_3550

Alternate gene names: 77465549

Gene position: 641096-639999 (Counterclockwise)

Preceding gene: 77465550

Following gene: 77465548

Centisome position: 67.98

GC content: 74.41

Gene sequence:

>1098_bases
GTGACCAAGGCCGCGGTCCGCGCCGAGGCCGAGGCGCTGTTCGCGGCCTTTCAGGCGGCGGGGGCGCTGCCGGTCGAGGC
GGACATCCTGCTGCCCGCGGGCACGCTCCTCGATCTTTACGGCGAGGACATCCGGGCGCGGGCCTATGTCACCTCGGACC
CGCTCCGGGGCGAGATGATGCTGCGCCCCGACTTCACCGTGCCCGTGGTGCAGGCCCATATGGCCGAAGGGGCCGAGCCC
GCGCGCTACACCTACATGGGCGAGGTCTTCCGGCGGCAGGAACATGCGGGGCCCCGGGCGTCGGAATATCTGCAGGTGGG
CTTCGAACTGTTCGACCGCACTGAGCCCGAGGCCGCCGATGCCGAGGTCTTCGCGCTGATCGCCGAGCTGCTGGCGCCTC
TGGGCCTTCAGGCGGCCACCGGCGACATCGGCATCCTGATGGCTGCGGTGCGCGGTCTCTCGACCACCGAGAAGCGCAAG
GCGGCGCTTCTGCGGCATGTCTGGCGGCCCACGCGGTTCCGCGCGCTGCTCGACCGGTTCGCCGGGCGCACGCCGGTGCC
CGAGGCGCGGCTGCGGCTGCTCGACCGGCTGGCCGGGGCGAGCGCCGTCGCGCTGATGGAGGCCGCGGGCCCGGCCATCG
GGCTCCGCGAGCCCTGCGAGATCGAGGCCCGCGCCGCGGCGCTGATCGAGGATGCCGAAGCCGCGCCGCTCGGGGCCGAG
GAGGCCGCGGTGCTCGACGATCTGCTGTCGCTCGAAGCTCCGGCGGCTGCGGCGCTCGGCCGCCTCGAGGCGCTGGCGCG
GCGGATGCCCGCGCTCGAGCCCTCGGTGGCGCGGTTCGGCCGCCGTCTCGCCGCGCTGGCGGCCCGCGGGATCGCGGTCG
AGCGGCTGCCGTTCGACGCCAGCCACGGCCAGAGCTCGCTCGAATATTACGACGGATTCGTCTTCAGCTTCCACGCCGCC
GACGCAGGGCTGCCGCCGGTCTCCACCGGCGGGCGTTACGACGCGCTGACGGCGGTGCTGGGGCAGGGGCGGTCCATCCC
GGCCATCGGGGGCGTGATCCGCCCGGGCCTCGTGGCCAGGCTGAAGGGGCTCGCATGA

Upstream 100 bases:

>100_bases
AGATCGCGGCCGGCGCGAGCCTCGAGGAATGGAAGAGCCGGCCAGCGCAGGTCGAGGTGCCGCGGGCGGATCTCGTCCGG
GCGGTGCAGGACATGCTCTC

Downstream 100 bases:

>100_bases
CGCTGAAGATCGGGGTGCCCTCGAAGGGCCGGCTGATGGAAAAGACCTTCGACTGGTTCGGCGCGCGCGGCGTGACCATG
CGCCAGACCGGGGCCGAGCG

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTKAAVRAEAEALFAAFQAAGALPVEADILLPAGTLLDLYGEDIRARAYVTSDPLRGEMMLRPDFTVPVVQAHMAEGAEP
ARYTYMGEVFRRQEHAGPRASEYLQVGFELFDRTEPEAADAEVFALIAELLAPLGLQAATGDIGILMAAVRGLSTTEKRK
AALLRHVWRPTRFRALLDRFAGRTPVPEARLRLLDRLAGASAVALMEAAGPAIGLREPCEIEARAAALIEDAEAAPLGAE
EAAVLDDLLSLEAPAAAALGRLEALARRMPALEPSVARFGRRLAALAARGIAVERLPFDASHGQSSLEYYDGFVFSFHAA
DAGLPPVSTGGRYDALTAVLGQGRSIPAIGGVIRPGLVARLKGLA

Sequences:

>Translated_365_residues
MTKAAVRAEAEALFAAFQAAGALPVEADILLPAGTLLDLYGEDIRARAYVTSDPLRGEMMLRPDFTVPVVQAHMAEGAEP
ARYTYMGEVFRRQEHAGPRASEYLQVGFELFDRTEPEAADAEVFALIAELLAPLGLQAATGDIGILMAAVRGLSTTEKRK
AALLRHVWRPTRFRALLDRFAGRTPVPEARLRLLDRLAGASAVALMEAAGPAIGLREPCEIEARAAALIEDAEAAPLGAE
EAAVLDDLLSLEAPAAAALGRLEALARRMPALEPSVARFGRRLAALAARGIAVERLPFDASHGQSSLEYYDGFVFSFHAA
DAGLPPVSTGGRYDALTAVLGQGRSIPAIGGVIRPGLVARLKGLA
>Mature_364_residues
TKAAVRAEAEALFAAFQAAGALPVEADILLPAGTLLDLYGEDIRARAYVTSDPLRGEMMLRPDFTVPVVQAHMAEGAEPA
RYTYMGEVFRRQEHAGPRASEYLQVGFELFDRTEPEAADAEVFALIAELLAPLGLQAATGDIGILMAAVRGLSTTEKRKA
ALLRHVWRPTRFRALLDRFAGRTPVPEARLRLLDRLAGASAVALMEAAGPAIGLREPCEIEARAAALIEDAEAAPLGAEE
AAVLDDLLSLEAPAAAALGRLEALARRMPALEPSVARFGRRLAALAARGIAVERLPFDASHGQSSLEYYDGFVFSFHAAD
AGLPPVSTGGRYDALTAVLGQGRSIPAIGGVIRPGLVARLKGLA

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38679; Mature: 38548

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAAVRAEAEALFAAFQAAGALPVEADILLPAGTLLDLYGEDIRARAYVTSDPLRGEMM
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCCEEEEEEECCCCCCCEE
LRPDFTVPVVQAHMAEGAEPARYTYMGEVFRRQEHAGPRASEYLQVGFELFDRTEPEAAD
ECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
AEVFALIAELLAPLGLQAATGDIGILMAAVRGLSTTEKRKAALLRHVWRPTRFRALLDRF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
AGRTPVPEARLRLLDRLAGASAVALMEAAGPAIGLREPCEIEARAAALIEDAEAAPLGAE
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
EAAVLDDLLSLEAPAAAALGRLEALARRMPALEPSVARFGRRLAALAARGIAVERLPFDA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCC
SHGQSSLEYYDGFVFSFHAADAGLPPVSTGGRYDALTAVLGQGRSIPAIGGVIRPGLVAR
CCCCCHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCHHCCHHHHH
LKGLA
HHCCC
>Mature Secondary Structure 
TKAAVRAEAEALFAAFQAAGALPVEADILLPAGTLLDLYGEDIRARAYVTSDPLRGEMM
CCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCCEEEEEEECCCCCCCEE
LRPDFTVPVVQAHMAEGAEPARYTYMGEVFRRQEHAGPRASEYLQVGFELFDRTEPEAAD
ECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
AEVFALIAELLAPLGLQAATGDIGILMAAVRGLSTTEKRKAALLRHVWRPTRFRALLDRF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
AGRTPVPEARLRLLDRLAGASAVALMEAAGPAIGLREPCEIEARAAALIEDAEAAPLGAE
CCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCH
EAAVLDDLLSLEAPAAAALGRLEALARRMPALEPSVARFGRRLAALAARGIAVERLPFDA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCC
SHGQSSLEYYDGFVFSFHAADAGLPPVSTGGRYDALTAVLGQGRSIPAIGGVIRPGLVAR
CCCCCHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHCCHHCCHHHHH
LKGLA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]