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The map label for this gene is 77465520

Identifier: 77465520

GI number: 77465520

Start: 598216

End: 599229

Strand: Direct

Name: 77465520

Synonym: RSP_3519

Alternate gene names: NA

Gene position: 598216-599229 (Clockwise)

Preceding gene: 77465519

Following gene: 77465526

Centisome position: 63.44

GC content: 66.57

Gene sequence:

>1014_bases
ATGCGCGTTCAGGACGTGTATAACGTGATCTATACCCATACGGAGGGCGAGCCGCTCTGCATCATCTACAGCGGTGTCCC
CTACCCCGCGGGCTCGACCATCCTCGAGAAGCGCGCCTTCCTCGAAGAGAACTACGACTGGCTGCGCAAGGCGCTGATGC
GCGAGCCGCGGGGCCATGCCGACATGTTCGGCGTCTTCCTGACCCCGCCCTCGTCGCGCGACTACGATGCGGGCCTGATC
TACATCGACGGCAAGGAATATTCCCACATGTGCGGCCATGGCACGATCGCCGTGGCGATGGCGATGGTGGCCAACGGGCT
TGTGGCCCGCGATCCCTCGGGGCTGACCCGCATCCGCTTCGAGACGACGGCGGGCCTCGTCGTGGCCGAGGTGGCGCACG
AGGGCGACCGCGTGCTCTGGACCCGGTTCGAGAACGTGCCGGCCTATGTGGCGGCGCAGGACATCGCCTTCGAACTGCCG
GGCTACGGGCCGCTGAAGGCGGATCTCGTCTGGGGCGGCAACTATTTCGGCATCATCGACCTGCGCGGCACGAGCCTCCG
GATCGCGCCCGAGAACGGCTCCGAGCTTTCGCGCATGGGTCTGATCGCCCGCGAGGAGATCCGCAAGAAGGTGAAAGTCC
AGCACCCGACCGAGGCGCATATCAACAATCTGAACTTCGTGACCTTCTGGCACGAGCCCACCATCGAGGGCTGCCTCTAC
AAGAACGTCCATGTCTTCTCGGCAGGCCAGCTCGACCGCTCGCCGGGCGGCACCGGGACCTCGGCCATGATGGCCTATTT
CGAGGCCCGGGGCGTGATCGGGCTGAACCAGCCGATCACCTCGGAGGGGCTTCTGGGCTCGGGCACCTTCGAGGGCTGCC
TGATCGGCGAGACGACGCTCGGCACGGTGCGCGCGGTGCGCCCCACGGTGAAGGGCACGGCCGGGATGCTCGGAACGGCC
AGCTGGACGATCAACCGCGAGGATCCGGTGGACGCGGGCTTCCTCGTCCTCTGA

Upstream 100 bases:

>100_bases
GTGGGCATCGTGCTGATCGACCTTCTCATCGGTCTGGATCTCTTGCCCGACAAGTGATCCCGGCCCCTCCGCCCCAGCCA
TCATCCCACAGGAGACAGAC

Downstream 100 bases:

>100_bases
CCCGCTTCGGTCGGCCCGATGGGCCGGCCGCTCCCCGCCGGGCTGCCGACGCGGCAGGCCCGGCATTCTTCCCTCGGGGC
GGGACAGATTCAGGTCGGCG

Product: putative proline racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHADMFGVFLTPPSSRDYDAGLI
YIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRFETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELP
GYGPLKADLVWGGNYFGIIDLRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLY
KNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTLGTVRAVRPTVKGTAGMLGTA
SWTINREDPVDAGFLVL

Sequences:

>Translated_337_residues
MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHADMFGVFLTPPSSRDYDAGLI
YIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRFETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELP
GYGPLKADLVWGGNYFGIIDLRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLY
KNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTLGTVRAVRPTVKGTAGMLGTA
SWTINREDPVDAGFLVL
>Mature_337_residues
MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHADMFGVFLTPPSSRDYDAGLI
YIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRFETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELP
GYGPLKADLVWGGNYFGIIDLRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLY
KNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTLGTVRAVRPTVKGTAGMLGTA
SWTINREDPVDAGFLVL

Specific function: Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways [H]

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=344, Percent_Identity=33.1395348837209, Blast_Score=188, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.4 [H]

Molecular weight: Translated: 36831; Mature: 36831

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHA
CCHHHEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCC
DMFGVFLTPPSSRDYDAGLIYIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRF
CEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEEE
ETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELPGYGPLKADLVWGGNYFGIID
ECCCCEEEEEECCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEEECCCEEEEEE
LRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLY
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCEEE
KNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTL
CCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEEECCCCC
GTVRAVRPTVKGTAGMLGTASWTINREDPVDAGFLVL
CHHEEECCCCCCCCCCEEEEEEEECCCCCCCCCEEEC
>Mature Secondary Structure
MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHA
CCHHHEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCC
DMFGVFLTPPSSRDYDAGLIYIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRF
CEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEEE
ETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELPGYGPLKADLVWGGNYFGIID
ECCCCEEEEEECCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEEECCCEEEEEE
LRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLY
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCEEE
KNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTL
CCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEEECCCCC
GTVRAVRPTVKGTAGMLGTASWTINREDPVDAGFLVL
CHHEEECCCCCCCCCCEEEEEEEECCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA