Click here to switch to the map view.

The map label for this gene is kamA [H]

Identifier: 77465239

GI number: 77465239

Start: 285991

End: 287013

Strand: Direct

Name: kamA [H]

Synonym: RSP_3227

Alternate gene names: 77465239

Gene position: 285991-287013 (Clockwise)

Preceding gene: 77465238

Following gene: 77465240

Centisome position: 30.33

GC content: 69.99

Gene sequence:

>1023_bases
ATGGACCGCGCGCTGGAAAATCTCAGGGATCTTTGCGACGCCGGGCTGACCGATCCGGCCGAGAACCGGCTGGAAGAGGT
TGCGCGCGCCTTCCGCATCCGGCTGACGCCGCAGATGGTGGCCGCCTCGGACGACCCGTCCGTGGCGCGCCAGTTCGTGC
CCACGCTCGACGAGCTGGAGATCCGCCCCGAGGAACTGGCCGATCCCATCGGCGACGCGGCGCGCAGCCCGGTGCCGGGC
CTGACCCATCGCTACCCCGACCGGGTCATCCTGCATGTCACCCGCACCTGCGATGTCTATTGCCGCTTCTGCTTCCGCCG
CGAGGTGGTGGGCAGCGAGGGGATCCTGCCCGAGGCCGACCTGTCGGCGGCGCTCGACTATATCGATGCCACGCCCTCGG
TGCGCGAGGTGATCCTCACCGGGGGCGATCCGCTCACCCTGTCGCCACGGCGGCTGCGCGCGATCATCGGGCGGCTCGGC
CAGATCGGCCATCTCGATCAGGTGCGCATCCACAGTCGCGTGCCGGTCGTGGCGCCCCACCGGATCGACGACAACATGCT
GCGCGCGCTGCTCGGGCCGATCCCCGTCTGGATCGTGGTCCATGTGAACCATCCCGGCGAGCTGCGCCTCGATGCGCGCG
CGGCGCTGGGGCGGCTGGCCGACCGGGGCATTCCACTCCTGTCGCAGTCGGTGCTGCTGCGCGGGGTGAACGATACCGTC
GACACGCTTGAGGAGCTGTTCCGGGCGCTGCTGCGCCTCAGGGTCAAGCCCTATTACCTGCATCATTGCGACCTCGCAAA
GGGCGCGGGCCATTTCCGCCCCACGATCGACGAGGGCCGCGCACTGATGGCCGAGCTCAGGCGCCGGATCACCGGGATCG
GCCTGCCGAGCTATGTGCTCGACCTGCCGGGCGGGTTCGGCAAGGTTCCCCTCACGTACGACCATCTGATCGCCGACGGT
CCCGGCCGCTGGCAGGTGCGCGACCCGCAGGGCGGCCTGCATCCCTACGCCGATCCCGACTGA

Upstream 100 bases:

>100_bases
CAGCCGGGGGACATTCCCGCCGACAGGGCGGATTCGCCGCTTGCGTCCGCGCGAGGGTGCGACGATAAGGCGCCCCTCTT
TTGCGATGGAGGCTGTCCTG

Downstream 100 bases:

>100_bases
CGGATGATCGATGGCGTGCTAGGCTCGGGCCCATCATCGGGGGAGGAGCCGCGCCATGGCCGACTGTCGCAAGCTGCGTC
CGACGGGTCTCTACGACGGC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDRALENLRDLCDAGLTDPAENRLEEVARAFRIRLTPQMVAASDDPSVARQFVPTLDELEIRPEELADPIGDAARSPVPG
LTHRYPDRVILHVTRTCDVYCRFCFRREVVGSEGILPEADLSAALDYIDATPSVREVILTGGDPLTLSPRRLRAIIGRLG
QIGHLDQVRIHSRVPVVAPHRIDDNMLRALLGPIPVWIVVHVNHPGELRLDARAALGRLADRGIPLLSQSVLLRGVNDTV
DTLEELFRALLRLRVKPYYLHHCDLAKGAGHFRPTIDEGRALMAELRRRITGIGLPSYVLDLPGGFGKVPLTYDHLIADG
PGRWQVRDPQGGLHPYADPD

Sequences:

>Translated_340_residues
MDRALENLRDLCDAGLTDPAENRLEEVARAFRIRLTPQMVAASDDPSVARQFVPTLDELEIRPEELADPIGDAARSPVPG
LTHRYPDRVILHVTRTCDVYCRFCFRREVVGSEGILPEADLSAALDYIDATPSVREVILTGGDPLTLSPRRLRAIIGRLG
QIGHLDQVRIHSRVPVVAPHRIDDNMLRALLGPIPVWIVVHVNHPGELRLDARAALGRLADRGIPLLSQSVLLRGVNDTV
DTLEELFRALLRLRVKPYYLHHCDLAKGAGHFRPTIDEGRALMAELRRRITGIGLPSYVLDLPGGFGKVPLTYDHLIADG
PGRWQVRDPQGGLHPYADPD
>Mature_340_residues
MDRALENLRDLCDAGLTDPAENRLEEVARAFRIRLTPQMVAASDDPSVARQFVPTLDELEIRPEELADPIGDAARSPVPG
LTHRYPDRVILHVTRTCDVYCRFCFRREVVGSEGILPEADLSAALDYIDATPSVREVILTGGDPLTLSPRRLRAIIGRLG
QIGHLDQVRIHSRVPVVAPHRIDDNMLRALLGPIPVWIVVHVNHPGELRLDARAALGRLADRGIPLLSQSVLLRGVNDTV
DTLEELFRALLRLRVKPYYLHHCDLAKGAGHFRPTIDEGRALMAELRRRITGIGLPSYVLDLPGGFGKVPLTYDHLIADG
PGRWQVRDPQGGLHPYADPD

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=269, Percent_Identity=38.6617100371747, Blast_Score=181, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 37730; Mature: 37730

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRALENLRDLCDAGLTDPAENRLEEVARAFRIRLTPQMVAASDDPSVARQFVPTLDELE
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHCCCHHHHC
IRPEELADPIGDAARSPVPGLTHRYPDRVILHVTRTCDVYCRFCFRREVVGSEGILPEAD
CCHHHHHCHHHHHHCCCCCCCHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHH
LSAALDYIDATPSVREVILTGGDPLTLSPRRLRAIIGRLGQIGHLDQVRIHSRVPVVAPH
HHHHHHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEECCC
RIDDNMLRALLGPIPVWIVVHVNHPGELRLDARAALGRLADRGIPLLSQSVLLRGVNDTV
CCCHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
DTLEELFRALLRLRVKPYYLHHCDLAKGAGHFRPTIDEGRALMAELRRRITGIGLPSYVL
HHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
DLPGGFGKVPLTYDHLIADGPGRWQVRDPQGGLHPYADPD
CCCCCCCCCCEEHHHHEECCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MDRALENLRDLCDAGLTDPAENRLEEVARAFRIRLTPQMVAASDDPSVARQFVPTLDELE
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHCCCHHHHC
IRPEELADPIGDAARSPVPGLTHRYPDRVILHVTRTCDVYCRFCFRREVVGSEGILPEAD
CCHHHHHCHHHHHHCCCCCCCHHCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHH
LSAALDYIDATPSVREVILTGGDPLTLSPRRLRAIIGRLGQIGHLDQVRIHSRVPVVAPH
HHHHHHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEECCC
RIDDNMLRALLGPIPVWIVVHVNHPGELRLDARAALGRLADRGIPLLSQSVLLRGVNDTV
CCCHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
DTLEELFRALLRLRVKPYYLHHCDLAKGAGHFRPTIDEGRALMAELRRRITGIGLPSYVL
HHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
DLPGGFGKVPLTYDHLIADGPGRWQVRDPQGGLHPYADPD
CCCCCCCCCCEEHHHHEECCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]