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The map label for this gene is actP [H]

Identifier: 77465156

GI number: 77465156

Start: 191896

End: 193626

Strand: Direct

Name: actP [H]

Synonym: RSP_3142

Alternate gene names: 77465156

Gene position: 191896-193626 (Clockwise)

Preceding gene: 77465155

Following gene: 77465170

Centisome position: 20.35

GC content: 66.72

Gene sequence:

>1731_bases
ATGAGCCGTCTCACGTCTTCGCGCCGCCTTGCAGTGGCCATGGCCGCGCTGATCCTGCTGCCGACGCTGGCGCTGGCCGC
GGGCCCGGATCTGGGCGAGGTCCAGAAGCAGGCCACGAACTTCACCGCCATCGGCATGTTCGCGGCCTTCGTGGTCTTCA
CGCTCTTCATCACCAAATGGGCCGCGGCCAAGACCAAGTCCGCCGCCGACTTCTACACCGCGGGCGGCGGCATCACCGGC
TTTCAGAACGGGCTCGCCATCGCGGGCGACTACATGTCGGCGGCCTCCTTCCTCGGGATTTCGGCAGCCGTGATGGCCTC
GGGCTTCGACGGGCTGATCTATTCCATCGGTTTCCTCGTGGGCTGGCCGATCCTGACCTTCCTCATGGCCGAGCGGCTGC
GGAACCTCGGGCAGTTCACCTTCGCGGACGTGGCGGCCTTCCGCTTCGCCCAGACGCCGGTGCGCGTGTTCGCGGCTTCC
TCGACCCTCGTCGTGGTGGCCTTTTACCTCATCGCGCAGATGGTGGGGGCGGGGCAGCTCATCAAGCTTCTCTTCGGGCT
CGAATATTGGGTGGCGGTCGTCATCGTGGGCGGGCTCATGATGATCTACGTCCTCTTCGGCGGAATGACGGCTACGACCT
GGGTGCAGATCATCAAGGCCTGCCTCCTTCTGGGCGGCGCCACCTTCATGGCCGTCATGGTGATGATGCAGTATGGCTTC
AGCCTCGAGCGGTTCTTCGCGGCAGCGGTCGAGGTGAAGGCGCAGATCGCGGCCCAGACCCCGGGCACCACGCCCGAGGA
TGCGGCGGCGGCCGGACAATCGATCATGGGGCCGGGCAAGTTCATCACCGACCCGATCTCGGCCATCTCCTTCGGCATGG
CGCTGATGTTCGGGACCGCGGGCCTGCCGCACATCCTGATGCGCTTCTTCACCGTGCCGGACGCCAAGGAGGCGCGGAAG
TCGGTGATGTGGGCGACCACCTGGATCGGCTACTTCTACCTCTTGACCTTCATCATCGGCTTCGGCGCGATCACCTTCGT
GCTGACGAGCCCGGGCTTCCTCGACGAGACGGGCGCGCTGGTGGGCGGCAGCAACATGGCGGCGATCCATCTCGCCAAGG
CCGTGGGCGGCAACCTCTTCCTCGGCTTCATCTCTGCGGTGGCCTTCGCCACGATCCTCGCGGTGGTGGCGGGCCTGACG
CTCGCCGGCGCTTCGGCCGTGTCGCACGACATCTATGCGACGGTCATCAAGAAGAACAAGGCGGGCAGCGCCGCGGAACT
CAAGGTCTCGCGTTATACGGTGCTGGCGCTCGGCGTGCTGGCGGTGGCTCTGGGCATCGTGTTCGAGAAGCAGAACATCG
CCTTCATGGTCTCGCTCGCCTTCGCCATCGCGGCTTCGGCCAACTTCCCGGTGCTGTTTCTGTCGGTGCTGTGGAAGGGC
TGCACGACGCGGGGCGTGGTGATCGGCGGCTTCATCGGCCTCGTCGTGTCGGTGGTGCTGACCGTGCTCTCGCCCTCGGT
CTGGGAGGCGACGCTGGGCTATGACAAGGGCTCGGCGCCCTTCCCCTATACCTCGCCCGCGCTATTCTCGATGACCGCGG
GGTTCGTGGGGATCTGGCTCTTCTCGACGCTCGACCGCAGCCTGCGCGGACGGCAGGACCGGGCGGGCTTCGTGGCGCAG
CAGGTCCGCTCCGAGACGGGCATCGGGGCCGCGGCCGCCTCCGCGCACTGA

Upstream 100 bases:

>100_bases
GCGTGATCGTCTTCACGGTCGTCATCACCGCCTTCTATGTGATGCGGGCCAACCGCGAATTCGACGATCTGACCGAGAAG
GTCCGGCGGGGGGCGATCCA

Downstream 100 bases:

>100_bases
AGCCTTCAGAAAACGAGCCTGCCGCCCTTCGGGGCGGCAGGCTTTTTCGTGCCGGCGGGACGGATCAGGCCGCGGCCTGA
GGCTCGCGCCAGCGCTGCGC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MSRLTSSRRLAVAMAALILLPTLALAAGPDLGEVQKQATNFTAIGMFAAFVVFTLFITKWAAAKTKSAADFYTAGGGITG
FQNGLAIAGDYMSAASFLGISAAVMASGFDGLIYSIGFLVGWPILTFLMAERLRNLGQFTFADVAAFRFAQTPVRVFAAS
STLVVVAFYLIAQMVGAGQLIKLLFGLEYWVAVVIVGGLMMIYVLFGGMTATTWVQIIKACLLLGGATFMAVMVMMQYGF
SLERFFAAAVEVKAQIAAQTPGTTPEDAAAAGQSIMGPGKFITDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARK
SVMWATTWIGYFYLLTFIIGFGAITFVLTSPGFLDETGALVGGSNMAAIHLAKAVGGNLFLGFISAVAFATILAVVAGLT
LAGASAVSHDIYATVIKKNKAGSAAELKVSRYTVLALGVLAVALGIVFEKQNIAFMVSLAFAIAASANFPVLFLSVLWKG
CTTRGVVIGGFIGLVVSVVLTVLSPSVWEATLGYDKGSAPFPYTSPALFSMTAGFVGIWLFSTLDRSLRGRQDRAGFVAQ
QVRSETGIGAAAASAH

Sequences:

>Translated_576_residues
MSRLTSSRRLAVAMAALILLPTLALAAGPDLGEVQKQATNFTAIGMFAAFVVFTLFITKWAAAKTKSAADFYTAGGGITG
FQNGLAIAGDYMSAASFLGISAAVMASGFDGLIYSIGFLVGWPILTFLMAERLRNLGQFTFADVAAFRFAQTPVRVFAAS
STLVVVAFYLIAQMVGAGQLIKLLFGLEYWVAVVIVGGLMMIYVLFGGMTATTWVQIIKACLLLGGATFMAVMVMMQYGF
SLERFFAAAVEVKAQIAAQTPGTTPEDAAAAGQSIMGPGKFITDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARK
SVMWATTWIGYFYLLTFIIGFGAITFVLTSPGFLDETGALVGGSNMAAIHLAKAVGGNLFLGFISAVAFATILAVVAGLT
LAGASAVSHDIYATVIKKNKAGSAAELKVSRYTVLALGVLAVALGIVFEKQNIAFMVSLAFAIAASANFPVLFLSVLWKG
CTTRGVVIGGFIGLVVSVVLTVLSPSVWEATLGYDKGSAPFPYTSPALFSMTAGFVGIWLFSTLDRSLRGRQDRAGFVAQ
QVRSETGIGAAAASAH
>Mature_575_residues
SRLTSSRRLAVAMAALILLPTLALAAGPDLGEVQKQATNFTAIGMFAAFVVFTLFITKWAAAKTKSAADFYTAGGGITGF
QNGLAIAGDYMSAASFLGISAAVMASGFDGLIYSIGFLVGWPILTFLMAERLRNLGQFTFADVAAFRFAQTPVRVFAASS
TLVVVAFYLIAQMVGAGQLIKLLFGLEYWVAVVIVGGLMMIYVLFGGMTATTWVQIIKACLLLGGATFMAVMVMMQYGFS
LERFFAAAVEVKAQIAAQTPGTTPEDAAAAGQSIMGPGKFITDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARKS
VMWATTWIGYFYLLTFIIGFGAITFVLTSPGFLDETGALVGGSNMAAIHLAKAVGGNLFLGFISAVAFATILAVVAGLTL
AGASAVSHDIYATVIKKNKAGSAAELKVSRYTVLALGVLAVALGIVFEKQNIAFMVSLAFAIAASANFPVLFLSVLWKGC
TTRGVVIGGFIGLVVSVVLTVLSPSVWEATLGYDKGSAPFPYTSPALFSMTAGFVGIWLFSTLDRSLRGRQDRAGFVAQQ
VRSETGIGAAAASAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=467, Percent_Identity=21.8415417558887, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790503, Length=569, Percent_Identity=62.7416520210896, Blast_Score=682, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=444, Percent_Identity=23.6486486486486, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60344; Mature: 60213

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SRLTSSRRLAVAMAALILLPTLALAAGPDLGEVQKQATNFTAIGMFAAFVVFTLFITKW
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH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HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA