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The map label for this gene is ywrO [H]

Identifier: 77465037

GI number: 77465037

Start: 55010

End: 55609

Strand: Direct

Name: ywrO [H]

Synonym: RSP_3025

Alternate gene names: 77465037

Gene position: 55010-55609 (Clockwise)

Preceding gene: 77465035

Following gene: 77465041

Centisome position: 5.83

GC content: 69.17

Gene sequence:

>600_bases
ATGACCAAGACGCTCGTCATCATCGCGCACCCCGACATGGCCCGGAGCCGGGTCAACGCCGCCTGGGCCGAGGCCCTGCG
CCGCGCCGGGGACATCACCCTGCGCGATCTTTCCGCCCTCTACCCGGACGGCATGATCGACGGCGCCGTCGAGCGGTCGC
TCCTTGAGGCGCACGACCGGATCATCCTGCAGTTTCCCCTGACCTGGTATTCCTGTCCGCCGATCCTGTCGGCCTGGCAG
ATCGCCATCCTGACGCGCGGCTGGGCCTATGGACCGGGAGGCCGTGCGCTCCGGCTGAAGACCTTGGGCGTCGCCCTCTC
GACCGGGTCGAACGGGCGGGACTACCAGCCCGACGGACGCTACGGGAGGACGCTCGAGGACGTGACGGTCCCGTTCGAGC
TGATGGCACGTCACACCGGGATGCACTACCTGCCGCCCTTCACCCTAACCGGCGTCCGCGAATGCGATGACGCCGCGGTT
GCAGCCTCCGCCCGGGCCTATCTCGATCATGTGCGCACCGCAAAGCCGCGCATCCTTGCCTCGGGCAGGGACGATGACCG
TGCCCGGACCGTCTATCCGCTGGAGGCGGGCGCGCGATAG

Upstream 100 bases:

>100_bases
CTGCACGGGAAATGCGGCTTCGTTCCGTACCGTGGAATTCCCCTTTTCGCGGCTTGTCGATCCGCCCTCGCGTGCGCCAC
CGTTCCGGCAGGAGGAGATC

Downstream 100 bases:

>100_bases
GCCGTCCCGCTCGTGCAGGCCTCCGCCGCAGCGCGCAGGTCTGACTTCAGGGCAGAGACATCGACCTTTGCCTTGGCGAA
ATAGGTGATGCCCAGCGTGC

Product: NAD(P)H oxidoreductase

Products: NAD(P); reduced acceptor [C]

Alternate protein names: GSP14 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTKTLVIIAHPDMARSRVNAAWAEALRRAGDITLRDLSALYPDGMIDGAVERSLLEAHDRIILQFPLTWYSCPPILSAWQ
IAILTRGWAYGPGGRALRLKTLGVALSTGSNGRDYQPDGRYGRTLEDVTVPFELMARHTGMHYLPPFTLTGVRECDDAAV
AASARAYLDHVRTAKPRILASGRDDDRARTVYPLEAGAR

Sequences:

>Translated_199_residues
MTKTLVIIAHPDMARSRVNAAWAEALRRAGDITLRDLSALYPDGMIDGAVERSLLEAHDRIILQFPLTWYSCPPILSAWQ
IAILTRGWAYGPGGRALRLKTLGVALSTGSNGRDYQPDGRYGRTLEDVTVPFELMARHTGMHYLPPFTLTGVRECDDAAV
AASARAYLDHVRTAKPRILASGRDDDRARTVYPLEAGAR
>Mature_198_residues
TKTLVIIAHPDMARSRVNAAWAEALRRAGDITLRDLSALYPDGMIDGAVERSLLEAHDRIILQFPLTWYSCPPILSAWQI
AILTRGWAYGPGGRALRLKTLGVALSTGSNGRDYQPDGRYGRTLEDVTVPFELMARHTGMHYLPPFTLTGVRECDDAAVA
ASARAYLDHVRTAKPRILASGRDDDRARTVYPLEAGAR

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Escherichia coli, GI1786231, Length=163, Percent_Identity=36.1963190184049, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789750, Length=167, Percent_Identity=37.125748502994, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21930; Mature: 21799

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLVIIAHPDMARSRVNAAWAEALRRAGDITLRDLSALYPDGMIDGAVERSLLEAHDR
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCHHHHHHHHHHHHCCE
IILQFPLTWYSCPPILSAWQIAILTRGWAYGPGGRALRLKTLGVALSTGSNGRDYQPDGR
EEEEECCCCCCCCCHHHHHHHEEEECCCEECCCCCEEEEEEEEEEEECCCCCCCCCCCCC
YGRTLEDVTVPFELMARHTGMHYLPPFTLTGVRECDDAAVAASARAYLDHVRTAKPRILA
CCCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
SGRDDDRARTVYPLEAGAR
CCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TKTLVIIAHPDMARSRVNAAWAEALRRAGDITLRDLSALYPDGMIDGAVERSLLEAHDR
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCHHHHHHHHHHHHCCE
IILQFPLTWYSCPPILSAWQIAILTRGWAYGPGGRALRLKTLGVALSTGSNGRDYQPDGR
EEEEECCCCCCCCCHHHHHHHEEEECCCEECCCCCEEEEEEEEEEEECCCCCCCCCCCCC
YGRTLEDVTVPFELMARHTGMHYLPPFTLTGVRECDDAAVAASARAYLDHVRTAKPRILA
CCCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
SGRDDDRARTVYPLEAGAR
CCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 9298659 [H]