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The map label for this gene is obgE

Identifier: 77465003

GI number: 77465003

Start: 17904

End: 18932

Strand: Direct

Name: obgE

Synonym: RSP_3822

Alternate gene names: 77465003

Gene position: 17904-18932 (Clockwise)

Preceding gene: 77465002

Following gene: 77465004

Centisome position: 1.9

GC content: 68.8

Gene sequence:

>1029_bases
ATGAAGTTCCTCGACCTCTGCAAAGTCTACATCCGCTCGGGCGGGGGCGGGGGCGGCTGCGTCAGCTTCCGGCGCGAGAA
GTTCATCGAGTTCGGCGGCCCCGACGGGGGCGACGGCGGCAATGGTGGCTCGGTCTGGGCCGAGGCCGTGGACGGGCTGA
ACACGCTGATCGACTTCCGCTACCAGCAGCATTTCTTCGCCAAGTCGGGGCAGCCCGGCATGGGCAGCCAGCGCACCGGC
AGGTCCGGCGACGACATCGTGCTGAAGGTGCCGGTCGGCACCGAGATCATCGACGAGGACGAAGAGACGGTGATCGCCGA
CCTGACCGAGGTGGGCCAGCGGGTGCTCCTCGCGCAGGGCGGCAATGGCGGCTGGGGCAACCTCCGCTTCAAGAGCTCGA
CCAACCGCGCGCCCGCCCGCGCGAATCCGGGCCAGCCCGGCATCGACCGCACGATCTGGCTGCGGCTGAAGCTCATCGCC
GACGCGGGCCTGCTGGGCCTGCCCAACGCCGGCAAATCGACCTTCCTCTCGGCCACCTCGAACGCCCGGCCGAAGATCGC
GGACTATCCCTTCACCACGCTGGTGCCGAACCTCGGCGTCGTGGGCGTGGACGGCAAGGAATTCGTGATCGCCGACATTC
CGGGCCTGATCGAGGGCGCCTCCGAAGGCCGCGGCCTCGGCGACCAGTTCCTCGCCCATGTCGAACGCTGCTCGGTGCTG
CTGCATCTGGTGGACGGCACCTCCTCGACCATCGTCAAGGATTACCGCACCATCATCGGCGAGCTCGAGGCCTATGGCGG
CGACCTCGCGCTGAAGCCGCGCATCACCGCGATGAACAAGATCGACGCGATGGACTCCAGGCAGATCTCGGACCGCCGCC
GCGCGCTCGAGAAGGCGACGGGAGGCAAGGTCTTCACCATCTCGGGCGTCGCGGGCACCGGCCTCATGGATGTGCTGCGC
GCGCTCTGGGCCGAGATCGACGGGGCGCGCGGCGACAAGGTGGAGGAGCACGCGCCGTGGCAACCCTGA

Upstream 100 bases:

>100_bases
CTCTGACCCGAGGGTCGCAGGCGCCAAACGACGGGCGGAGGCTTGAGCCTCGGCCCGTTTCTCTCTATCGCCAGAAGCGA
CCAATCGGAAAGTTCCGCCC

Downstream 100 bases:

>100_bases
TGCCGCTTCAGGCGCCGGATATCCGCAGCGCCAAGCGTCTGGTCGTGAAGATCGGCTCGGCGCTCCTCGTGGATGGCGAG
GGGCTGCGCCGCCAATGGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKFLDLCKVYIRSGGGGGGCVSFRREKFIEFGGPDGGDGGNGGSVWAEAVDGLNTLIDFRYQQHFFAKSGQPGMGSQRTG
RSGDDIVLKVPVGTEIIDEDEETVIADLTEVGQRVLLAQGGNGGWGNLRFKSSTNRAPARANPGQPGIDRTIWLRLKLIA
DAGLLGLPNAGKSTFLSATSNARPKIADYPFTTLVPNLGVVGVDGKEFVIADIPGLIEGASEGRGLGDQFLAHVERCSVL
LHLVDGTSSTIVKDYRTIIGELEAYGGDLALKPRITAMNKIDAMDSRQISDRRRALEKATGGKVFTISGVAGTGLMDVLR
ALWAEIDGARGDKVEEHAPWQP

Sequences:

>Translated_342_residues
MKFLDLCKVYIRSGGGGGGCVSFRREKFIEFGGPDGGDGGNGGSVWAEAVDGLNTLIDFRYQQHFFAKSGQPGMGSQRTG
RSGDDIVLKVPVGTEIIDEDEETVIADLTEVGQRVLLAQGGNGGWGNLRFKSSTNRAPARANPGQPGIDRTIWLRLKLIA
DAGLLGLPNAGKSTFLSATSNARPKIADYPFTTLVPNLGVVGVDGKEFVIADIPGLIEGASEGRGLGDQFLAHVERCSVL
LHLVDGTSSTIVKDYRTIIGELEAYGGDLALKPRITAMNKIDAMDSRQISDRRRALEKATGGKVFTISGVAGTGLMDVLR
ALWAEIDGARGDKVEEHAPWQP
>Mature_342_residues
MKFLDLCKVYIRSGGGGGGCVSFRREKFIEFGGPDGGDGGNGGSVWAEAVDGLNTLIDFRYQQHFFAKSGQPGMGSQRTG
RSGDDIVLKVPVGTEIIDEDEETVIADLTEVGQRVLLAQGGNGGWGNLRFKSSTNRAPARANPGQPGIDRTIWLRLKLIA
DAGLLGLPNAGKSTFLSATSNARPKIADYPFTTLVPNLGVVGVDGKEFVIADIPGLIEGASEGRGLGDQFLAHVERCSVL
LHLVDGTSSTIVKDYRTIIGELEAYGGDLALKPRITAMNKIDAMDSRQISDRRRALEKATGGKVFTISGVAGTGLMDVLR
ALWAEIDGARGDKVEEHAPWQP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=331, Percent_Identity=41.9939577039275, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI111955139, Length=297, Percent_Identity=39.0572390572391, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI111955063, Length=131, Percent_Identity=45.8015267175573, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557537, Length=120, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI58761500, Length=166, Percent_Identity=31.3253012048193, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4758796, Length=114, Percent_Identity=36.8421052631579, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=326, Percent_Identity=53.9877300613497, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1787454, Length=102, Percent_Identity=38.2352941176471, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=36.1963190184049, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17552324, Length=311, Percent_Identity=32.1543408360129, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=99, Percent_Identity=39.3939393939394, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=114, Percent_Identity=35.9649122807018, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=35.0877192982456, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=138, Percent_Identity=42.7536231884058, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=115, Percent_Identity=36.5217391304348, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=86, Percent_Identity=40.6976744186046, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129375, Length=325, Percent_Identity=36.9230769230769, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24585318, Length=306, Percent_Identity=37.2549019607843, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24640873, Length=179, Percent_Identity=29.0502793296089, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640877, Length=179, Percent_Identity=29.0502793296089, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640875, Length=179, Percent_Identity=29.0502793296089, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356473, Length=123, Percent_Identity=35.7723577235772, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17981711, Length=114, Percent_Identity=35.0877192982456, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_RHOS1 (A3PQJ0)

Other databases:

- EMBL:   CP000578
- RefSeq:   YP_001045378.1
- ProteinModelPortal:   A3PQJ0
- SMR:   A3PQJ0
- STRING:   A3PQJ0
- GeneID:   4899112
- GenomeReviews:   CP000578_GR
- KEGG:   rsh:Rsph17029_3514
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- BioCyc:   RSPH349101:RSPH17029_3514-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36384; Mature: 36384

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDLCKVYIRSGGGGGGCVSFRREKFIEFGGPDGGDGGNGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFFAKSGQPGMGSQRTGRSGDDIVLKVPVGTEIIDEDEETVIADLTEVGQRVLLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHCCEEEEEEC
GNGGWGNLRFKSSTNRAPARANPGQPGIDRTIWLRLKLIADAGLLGLPNAGKSTFLSATS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCCCEEECCC
NARPKIADYPFTTLVPNLGVVGVDGKEFVIADIPGLIEGASEGRGLGDQFLAHVERCSVL
CCCCCCCCCCHHHHCCCCCEEECCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSSTIVKDYRTIIGELEAYGGDLALKPRITAMNKIDAMDSRQISDRRRALEKAT
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHC
GGKVFTISGVAGTGLMDVLRALWAEIDGARGDKVEEHAPWQP
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLDLCKVYIRSGGGGGGCVSFRREKFIEFGGPDGGDGGNGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFFAKSGQPGMGSQRTGRSGDDIVLKVPVGTEIIDEDEETVIADLTEVGQRVLLAQG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHCCEEEEEEC
GNGGWGNLRFKSSTNRAPARANPGQPGIDRTIWLRLKLIADAGLLGLPNAGKSTFLSATS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCCCCCEEECCC
NARPKIADYPFTTLVPNLGVVGVDGKEFVIADIPGLIEGASEGRGLGDQFLAHVERCSVL
CCCCCCCCCCHHHHCCCCCEEECCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSSTIVKDYRTIIGELEAYGGDLALKPRITAMNKIDAMDSRQISDRRRALEKAT
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHC
GGKVFTISGVAGTGLMDVLRALWAEIDGARGDKVEEHAPWQP
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA