Click here to switch to the map view.

The map label for this gene is ubiA

Identifier: 77461825

GI number: 77461825

Start: 6276475

End: 6277365

Strand: Direct

Name: ubiA

Synonym: Pfl01_5604

Alternate gene names: 77461825

Gene position: 6276475-6277365 (Clockwise)

Preceding gene: 77461824

Following gene: 77461827

Centisome position: 97.48

GC content: 61.95

Gene sequence:

>891_bases
ATGTATCAAAGCCTGCTCAAATCTCTGAATCGCTTGAACCCGCGCGCCTGGGACTTCATCCAGCTGACCCGGATGGACAA
GCCGATCGGCATTTACCTGCTGCTGTGGCCGACCCTCTGGGCCCTGTGGATTGCCGGTAAAGGCTCGCCATCGCTGGCCA
ATATCGTGATTTTCGTCCTCGGCGTGGTGCTGACCCGTGCCGGCGGCTGCGTGATCAACGACTGGGCCGACCGCAAGGTC
GACGGCCACGTCAAACGCACTGCGCAGCGACCTATTGCTGCCGGCAAGATCAGCTCGAAAGAGGCGCTGGTGTTCTTTGC
GCTGCTGATGGGCGTGAGTTTCCTGCTGGTGCTGTGCACCAACGCCGCAACCATCTGGCTGTCGCTGGGCGGTCTGGCGC
TGGCGTTCACCTATCCGTTCATGAAGCGCTACACCTACTACCCGCAAGTGGTGCTGGGGGCGGCGTTCTCCTGGGGGATG
CCGATGGCGTTCACCGCCGAAACCGGTGAGCTGCCAGCAACGGCCTGGCTGCTGTGGATCGCCAATCTGCTGTGGACGGT
GGGTTACGACACTTATTACGCGATGACTGACCGCGACGATGACCTGAAGATCGGCGTGAAATCCACGGCGATCCTGTTCG
GTGATGCCGACCGGGTGATCATCCTGACCTTGCAGGTACTGTCGCTGGGTTGCCTGGTGCTGGCGGGGTCGAAATTCGAG
CTGGGGATGTGGTTCCACCTCGGCCTGCTGGTGGCGGCCGGGTGCTATGCCTGGGAGTTCTGGTACACCCGCGACCGGGA
CCGGATGCGTTGCTTTAGGGCGTTCCTGCACAACCACTGGGCCGGGCTGGCGATTTTCGTCGGGATCGTGCTGGATTACG
CGTTGCGCTGA

Upstream 100 bases:

>100_bases
GGCGTTCGCGTTTCGACCGTGGCGCATTGAGCGTACTGGTGGCGGAGATTTTCCTGCCTACGCTGTGGGAAGCCGTCCGC
GCCCGTCCGGAGAACTGCTG

Downstream 100 bases:

>100_bases
TCCACAGAACCTGTGGGAGCGAGTTTGCTCGCTCCCACAGGGCATTTGCGTTTATTTGTGCTCGCGCATCACGTGCCACA
CGTCCTTCATCTTGTCGCCG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MYQSLLKSLNRLNPRAWDFIQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLANIVIFVLGVVLTRAGGCVINDWADRKV
DGHVKRTAQRPIAAGKISSKEALVFFALLMGVSFLLVLCTNAATIWLSLGGLALAFTYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPATAWLLWIANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQVLSLGCLVLAGSKFE
LGMWFHLGLLVAAGCYAWEFWYTRDRDRMRCFRAFLHNHWAGLAIFVGIVLDYALR

Sequences:

>Translated_296_residues
MYQSLLKSLNRLNPRAWDFIQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLANIVIFVLGVVLTRAGGCVINDWADRKV
DGHVKRTAQRPIAAGKISSKEALVFFALLMGVSFLLVLCTNAATIWLSLGGLALAFTYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPATAWLLWIANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQVLSLGCLVLAGSKFE
LGMWFHLGLLVAAGCYAWEFWYTRDRDRMRCFRAFLHNHWAGLAIFVGIVLDYALR
>Mature_296_residues
MYQSLLKSLNRLNPRAWDFIQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLANIVIFVLGVVLTRAGGCVINDWADRKV
DGHVKRTAQRPIAAGKISSKEALVFFALLMGVSFLLVLCTNAATIWLSLGGLALAFTYPFMKRYTYYPQVVLGAAFSWGM
PMAFTAETGELPATAWLLWIANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQVLSLGCLVLAGSKFE
LGMWFHLGLLVAAGCYAWEFWYTRDRDRMRCFRAFLHNHWAGLAIFVGIVLDYALR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=37.9061371841155, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=53.4545454545455, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1786631, Length=187, Percent_Identity=28.3422459893048, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553718, Length=286, Percent_Identity=34.2657342657343, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32565247, Length=292, Percent_Identity=33.9041095890411, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553720, Length=343, Percent_Identity=28.2798833819242, Blast_Score=123, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=142, Percent_Identity=39.4366197183099, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=141, Percent_Identity=39.0070921985816, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=293, Percent_Identity=33.1058020477816, Blast_Score=159, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21355567, Length=291, Percent_Identity=36.426116838488, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_PSEPF (Q3K4G3)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_351332.1
- STRING:   Q3K4G3
- GeneID:   3717680
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_5604
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- BioCyc:   PFLU205922:PFL_5604-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x165d2e70)-; HASH(0x16bcd328)-; HASH(0x16aaa780)-; HASH(0x1667d720)-; HASH(0x15864cd8)-; HASH(0x168931e0)-; HASH(0x1340957c)-; HASH(0x16341edc)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQSLLKSLNRLNPRAWDFIQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLANIVIFVL
CHHHHHHHHHHCCCCCCHHEEEECCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHH
GVVLTRAGGCVINDWADRKVDGHVKRTAQRPIAAGKISSKEALVFFALLMGVSFLLVLCT
HHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NAATIWLSLGGLALAFTYPFMKRYTYYPQVVLGAAFSWGMPMAFTAETGELPATAWLLWI
CHHHEEHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
ANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQVLSLGCLVLAGSKFE
HHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHEECCCCC
LGMWFHLGLLVAAGCYAWEFWYTRDRDRMRCFRAFLHNHWAGLAIFVGIVLDYALR
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MYQSLLKSLNRLNPRAWDFIQLTRMDKPIGIYLLLWPTLWALWIAGKGSPSLANIVIFVL
CHHHHHHHHHHCCCCCCHHEEEECCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHH
GVVLTRAGGCVINDWADRKVDGHVKRTAQRPIAAGKISSKEALVFFALLMGVSFLLVLCT
HHHHHCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NAATIWLSLGGLALAFTYPFMKRYTYYPQVVLGAAFSWGMPMAFTAETGELPATAWLLWI
CHHHEEHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
ANLLWTVGYDTYYAMTDRDDDLKIGVKSTAILFGDADRVIILTLQVLSLGCLVLAGSKFE
HHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEECCCCCEEEHHHHHHHHHHHHEECCCCC
LGMWFHLGLLVAAGCYAWEFWYTRDRDRMRCFRAFLHNHWAGLAIFVGIVLDYALR
HHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA