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The map label for this gene is exbB [H]

Identifier: 77461776

GI number: 77461776

Start: 6222875

End: 6223828

Strand: Direct

Name: exbB [H]

Synonym: Pfl01_5555

Alternate gene names: 77461776

Gene position: 6222875-6223828 (Clockwise)

Preceding gene: 77461774

Following gene: 77461777

Centisome position: 96.65

GC content: 65.3

Gene sequence:

>954_bases
ATGACACGCATTCAAAACTCCGCTTCGCCAACCAACCGACCTCGCGCCTGGAGCGCCGTGGCTGCCCTGCTGCTCAGCCT
GATGCTGGCGCCAGTCGCCGCCTTCGCTGACGCACAAGCCCCGGCCGCGCCAGCCGCCACCGAGCAAAGCGCTCCGGCCG
CCGCACCTGCCGCAACCGACCCGGTGCAGGCCGTAGAGGCCAGCACCGCCGACGCGCCGGAAGTCCTCGAAGCCGACAAC
ACCCTGGGCATGGCCCACGACCTGTCGCCATGGGGCATGTACCAGAACGCCGACGTGATCGTTAAAGCCGTGATGATCGG
CCTGGCCATCGCCTCGATCATCACCTGGACCATCTGGATCGCCAAGGGCTTCGAGCTGATGGGCGCCAAACGCCGCCTGC
GTGGCGAGATCGCCGCCCTGAAAAAAGCCGCCACCCTCAAAGAAGCCAGCGCCACCGCCGCGAAGGAAGGCACCCTCGCC
AACCTGCTGGTGCACGACGCGCTGGAAGAAATGCGCCTGTCGACCAACGCCCGCGAGAAAGAAGGCATCAAGGAACGCGT
CAGCTTCCGCCTCGAGCGCCTGGTTGCCGCCTGTGGCCGCAACATGAGCAGCGGCACCGGCGTTCTCGCCACCATCGGTT
CCACCGCACCGTTCGTCGGTCTGTTCGGTACCGTGTGGGGCATCATGAACAGCTTCATCGGCATTGCCAAAACCCAGACC
ACCAACCTTGCCGTCGTAGCACCGGGTATCGCTGAAGCGCTGCTGGCTACCGCTCTGGGTCTGGTGGCCGCGATTCCTGC
CGTGGTCATCTACAACGTCTTCGCCCGCTCCATCGCCGGTTACAAGGCTCAGGTGTCCGATGCGTCGGCTCAGGTGCTGC
TGCTGGTCAGCCGCGACCTCGACCACCAGCCTGAGCGCAACAGCTCGCAACCGCACATGGTGAAAGTGGGGTAA

Upstream 100 bases:

>100_bases
TGTTAACAAGAATTACTTGCAATAATGCACGCCACTTTTGTTCTCGGCCTCACGAGGCCTGGAAGAGCATTACCGTTTTT
CTATCTCAGGTCCGGCCAGC

Downstream 100 bases:

>100_bases
TCGGCCATGGGCCTGCATTTGAAAGAAGGCGCAGACGACGATCTGGCCGAGAACCACGAAATCAACGTCACGCCGTTCAT
CGACGTGATGCTGGTGCTGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTRIQNSASPTNRPRAWSAVAALLLSLMLAPVAAFADAQAPAAPAATEQSAPAAAPAATDPVQAVEASTADAPEVLEADN
TLGMAHDLSPWGMYQNADVIVKAVMIGLAIASIITWTIWIAKGFELMGAKRRLRGEIAALKKAATLKEASATAAKEGTLA
NLLVHDALEEMRLSTNAREKEGIKERVSFRLERLVAACGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDLDHQPERNSSQPHMVKVG

Sequences:

>Translated_317_residues
MTRIQNSASPTNRPRAWSAVAALLLSLMLAPVAAFADAQAPAAPAATEQSAPAAAPAATDPVQAVEASTADAPEVLEADN
TLGMAHDLSPWGMYQNADVIVKAVMIGLAIASIITWTIWIAKGFELMGAKRRLRGEIAALKKAATLKEASATAAKEGTLA
NLLVHDALEEMRLSTNAREKEGIKERVSFRLERLVAACGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDLDHQPERNSSQPHMVKVG
>Mature_316_residues
TRIQNSASPTNRPRAWSAVAALLLSLMLAPVAAFADAQAPAAPAATEQSAPAAAPAATDPVQAVEASTADAPEVLEADNT
LGMAHDLSPWGMYQNADVIVKAVMIGLAIASIITWTIWIAKGFELMGAKRRLRGEIAALKKAATLKEASATAAKEGTLAN
LLVHDALEEMRLSTNAREKEGIKERVSFRLERLVAACGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQTT
NLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDLDHQPERNSSQPHMVKVG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=235, Percent_Identity=62.1276595744681, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1786958, Length=217, Percent_Identity=32.7188940092166, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 33016; Mature: 32885

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIQNSASPTNRPRAWSAVAALLLSLMLAPVAAFADAQAPAAPAATEQSAPAAAPAATD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PVQAVEASTADAPEVLEADNTLGMAHDLSPWGMYQNADVIVKAVMIGLAIASIITWTIWI
HHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AKGFELMGAKRRLRGEIAALKKAATLKEASATAAKEGTLANLLVHDALEEMRLSTNAREK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHH
EGIKERVSFRLERLVAACGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCC
DHQPERNSSQPHMVKVG
CCCCCCCCCCCCEEECC
>Mature Secondary Structure 
TRIQNSASPTNRPRAWSAVAALLLSLMLAPVAAFADAQAPAAPAATEQSAPAAAPAATD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PVQAVEASTADAPEVLEADNTLGMAHDLSPWGMYQNADVIVKAVMIGLAIASIITWTIWI
HHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AKGFELMGAKRRLRGEIAALKKAATLKEASATAAKEGTLANLLVHDALEEMRLSTNAREK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHH
EGIKERVSFRLERLVAACGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQT
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDL
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCC
DHQPERNSSQPHMVKVG
CCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]