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The map label for this gene is xcpR [H]

Identifier: 77461645

GI number: 77461645

Start: 6089033

End: 6090817

Strand: Direct

Name: xcpR [H]

Synonym: Pfl01_5424

Alternate gene names: 77461645

Gene position: 6089033-6090817 (Clockwise)

Preceding gene: 77461644

Following gene: 77461646

Centisome position: 94.57

GC content: 63.81

Gene sequence:

>1785_bases
ATGTCCGTTCAACTCGCCACTCAGGATCGCTGGCTGGATCTCAATGAGGTACTGCGTGAACTGGTCGCCCAAGGGTTCAT
CTGCCAGGACTCGGCCGAGCAGGCGCTAAATGCCCGGCGTCGGCATGCCGCCCACGGCCAGAAGCATCCGCTGGAATTCA
TCGCCAGCCAGCAACTGGACGATCTCAGCCGTCCGGGCAAACACCTCGACCTGGAAAGCCTGACCCTGTGGCTGGCGCAG
CAGGCCGGCCAGCCGTACCTGCGGATCGATCCGCTGAAGATCAACGTCGCCGCCGTCACGCCGCTGATGTCCTACGCCTT
TGCCCAGCGCCACAAGATTCTCGCGGTGTCGGTCGACCGCGACGCGGTCACCGTGGCCAGCGCCCAGCCCTACGTCAGCG
GCTGGGAGGCGGATCTGACTCACGTCCTGAAACTGCCGATCAAACGGGTGGTGGCCAACCCGGCGGACATTCAGCGTTTC
AGCGTGGAATTCTTTCGCCTCGCCAAATCGGTCAGCGGCGCCAGCAATGCCGATGCGCAGAGCGGCAACCTCGGCAACTT
CGAACAGTTGCTCAACCTCGGCGCCAGCGATCAGGAGCCCGACGCCAACGACGCGCACATCGTCAACATCGTCGACTGGC
TGTTCCAGTACGCCTTCCAGCAACGGGCCAGCGATATCCACATCGAACCCCGGCGCGAGCAAGGCACGGTGCGTTTTCGC
ATCGACGGCGTGCTGCACAACGTCTATCAATTCCCGCCGCAGGTGACGATGGCCATCGTCAGCCGCCTGAAAAGCCTTGG
CCGGATGAACGTCGCCGAGAAACGCAAACCCCAGGACGGCCGGGTCAAGACCAAGACCCCGGACGGCGGTGAAGTCGAGT
TGCGGCTGTCGACCCTGCCCACCGCATTCGGCGAAAAAATGGTGATGCGGATCTTCGACCCGGAAGTCCTGCTCAAGGAT
TTCGATCAACTGGGGTTTTCCACCGACGACCTGCGGCGCTGGCAGGACATGACCCGCCAGCCCAACGGTATCATCCTGGT
CACCGGGCCGACCGGTTCCGGCAAGACCACCACGCTGTACACCACGCTGAAAAAACTGGCGACCCCGGAGGTCAACCTCT
GCACCATTGAGGACCCGATCGAGATGGTCGAGCCGGCCTTCAACCAGATGCAGGTCCAGCACAACATCGACCTGACCTTC
GCCGCCGGCGTGCGTGCGCTGATGCGGCAGGACCCGGACATCATCATGATCGGCGAAATCCGCGATCTGGAAACGGCCGA
AATGGCGATCCAGGCGGCGCTGACCGGGCACCTGGTGCTCTCGACCCTGCACACCAACGACGCGCCGAGCGCCATCAGCC
GCCTGCTGGAACTCGGCGTGCCGCATTACCTGATCAAGGCCACCGTGCTCGGTGTGATGGCGCAACGACTGGTGCGAACC
CTTTGCCCGCACTGCAAGGCGCCGCTGACGCTGGACGAAGAAGACTGGCAAACCCTGACCCGGCCGTGGCAGGCGCCGCT
GCCGGGCAATGCGCAACGGGCCATCGGTTGCCTGGAGTGCCGCGACACCGGTTATCACGGGCGTGCCGGGGTCTACGAAA
TCATGCAACTGAGCGACAGCCTCAAGGCCTTGATCAGCCCCGACACCGATCTCACCGCGATCCGCCGGCAGGCGTTCAAG
GAAGGCATGCGCAGCCTGCGCTTGTCCGGCGCGCAGAAAGTCGCGGCCGGGCTGACGACGCTTGAGGAAGTGCTGCGGGT
GACACCACAGAGCGAGCAGAAATAA

Upstream 100 bases:

>100_bases
GGCTGGCTGACAAGAACCGAAACGTCTTCGTCGGGTAGTGGCCCAACGGTCAGCGGGGCCACGACTATCCTTTGCGCACT
GTCGTTCAAAAGGAGCCCGC

Downstream 100 bases:

>100_bases
GTGCTCACGGAACCGGATCGGGGAAACGGCGATCCAACCGGTTATTCAACACCAGTGGAGTCACCCAACATGCGTCTCAA
ACTTGCTGTCGCCACCCTTG

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MSVQLATQDRWLDLNEVLRELVAQGFICQDSAEQALNARRRHAAHGQKHPLEFIASQQLDDLSRPGKHLDLESLTLWLAQ
QAGQPYLRIDPLKINVAAVTPLMSYAFAQRHKILAVSVDRDAVTVASAQPYVSGWEADLTHVLKLPIKRVVANPADIQRF
SVEFFRLAKSVSGASNADAQSGNLGNFEQLLNLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
IDGVLHNVYQFPPQVTMAIVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLPTAFGEKMVMRIFDPEVLLKD
FDQLGFSTDDLRRWQDMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATPEVNLCTIEDPIEMVEPAFNQMQVQHNIDLTF
AAGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRLLELGVPHYLIKATVLGVMAQRLVRT
LCPHCKAPLTLDEEDWQTLTRPWQAPLPGNAQRAIGCLECRDTGYHGRAGVYEIMQLSDSLKALISPDTDLTAIRRQAFK
EGMRSLRLSGAQKVAAGLTTLEEVLRVTPQSEQK

Sequences:

>Translated_594_residues
MSVQLATQDRWLDLNEVLRELVAQGFICQDSAEQALNARRRHAAHGQKHPLEFIASQQLDDLSRPGKHLDLESLTLWLAQ
QAGQPYLRIDPLKINVAAVTPLMSYAFAQRHKILAVSVDRDAVTVASAQPYVSGWEADLTHVLKLPIKRVVANPADIQRF
SVEFFRLAKSVSGASNADAQSGNLGNFEQLLNLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
IDGVLHNVYQFPPQVTMAIVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLPTAFGEKMVMRIFDPEVLLKD
FDQLGFSTDDLRRWQDMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATPEVNLCTIEDPIEMVEPAFNQMQVQHNIDLTF
AAGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRLLELGVPHYLIKATVLGVMAQRLVRT
LCPHCKAPLTLDEEDWQTLTRPWQAPLPGNAQRAIGCLECRDTGYHGRAGVYEIMQLSDSLKALISPDTDLTAIRRQAFK
EGMRSLRLSGAQKVAAGLTTLEEVLRVTPQSEQK
>Mature_593_residues
SVQLATQDRWLDLNEVLRELVAQGFICQDSAEQALNARRRHAAHGQKHPLEFIASQQLDDLSRPGKHLDLESLTLWLAQQ
AGQPYLRIDPLKINVAAVTPLMSYAFAQRHKILAVSVDRDAVTVASAQPYVSGWEADLTHVLKLPIKRVVANPADIQRFS
VEFFRLAKSVSGASNADAQSGNLGNFEQLLNLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFRI
DGVLHNVYQFPPQVTMAIVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLPTAFGEKMVMRIFDPEVLLKDF
DQLGFSTDDLRRWQDMTRQPNGIILVTGPTGSGKTTTLYTTLKKLATPEVNLCTIEDPIEMVEPAFNQMQVQHNIDLTFA
AGVRALMRQDPDIIMIGEIRDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRLLELGVPHYLIKATVLGVMAQRLVRTL
CPHCKAPLTLDEEDWQTLTRPWQAPLPGNAQRAIGCLECRDTGYHGRAGVYEIMQLSDSLKALISPDTDLTAIRRQAFKE
GMRSLRLSGAQKVAAGLTTLEEVLRVTPQSEQK

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=499, Percent_Identity=36.4729458917836, Blast_Score=324, Evalue=1e-89,
Organism=Escherichia coli, GI1786296, Length=377, Percent_Identity=44.2970822281167, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI87082188, Length=168, Percent_Identity=39.8809523809524, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 66085; Mature: 65953

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQLATQDRWLDLNEVLRELVAQGFICQDSAEQALNARRRHAAHGQKHPLEFIASQQLD
CCEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DLSRPGKHLDLESLTLWLAQQAGQPYLRIDPLKINVAAVTPLMSYAFAQRHKILAVSVDR
HHHCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHCCEEEEEEECC
DAVTVASAQPYVSGWEADLTHVLKLPIKRVVANPADIQRFSVEFFRLAKSVSGASNADAQ
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SGNLGNFEQLLNLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
CCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
IDGVLHNVYQFPPQVTMAIVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLP
EHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCCEEEEEEECCC
TAFGEKMVMRIFDPEVLLKDFDQLGFSTDDLRRWQDMTRQPNGIILVTGPTGSGKTTTLY
CHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
TTLKKLATPEVNLCTIEDPIEMVEPAFNQMQVQHNIDLTFAAGVRALMRQDPDIIMIGEI
HHHHHHCCCCCEEEEECCCHHHHHHHHHHEEHHHCCCEEHHHHHHHHHHCCCCEEEECCC
RDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRLLELGVPHYLIKATVLGVMAQRLVRT
CCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LCPHCKAPLTLDEEDWQTLTRPWQAPLPGNAQRAIGCLECRDTGYHGRAGVYEIMQLSDS
HCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHH
LKALISPDTDLTAIRRQAFKEGMRSLRLSGAQKVAAGLTTLEEVLRVTPQSEQK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVQLATQDRWLDLNEVLRELVAQGFICQDSAEQALNARRRHAAHGQKHPLEFIASQQLD
CEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
DLSRPGKHLDLESLTLWLAQQAGQPYLRIDPLKINVAAVTPLMSYAFAQRHKILAVSVDR
HHHCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHCCEEEEEEECC
DAVTVASAQPYVSGWEADLTHVLKLPIKRVVANPADIQRFSVEFFRLAKSVSGASNADAQ
CEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
SGNLGNFEQLLNLGASDQEPDANDAHIVNIVDWLFQYAFQQRASDIHIEPRREQGTVRFR
CCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
IDGVLHNVYQFPPQVTMAIVSRLKSLGRMNVAEKRKPQDGRVKTKTPDGGEVELRLSTLP
EHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCCEEEEEEECCC
TAFGEKMVMRIFDPEVLLKDFDQLGFSTDDLRRWQDMTRQPNGIILVTGPTGSGKTTTLY
CHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHH
TTLKKLATPEVNLCTIEDPIEMVEPAFNQMQVQHNIDLTFAAGVRALMRQDPDIIMIGEI
HHHHHHCCCCCEEEEECCCHHHHHHHHHHEEHHHCCCEEHHHHHHHHHHCCCCEEEECCC
RDLETAEMAIQAALTGHLVLSTLHTNDAPSAISRLLELGVPHYLIKATVLGVMAQRLVRT
CCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LCPHCKAPLTLDEEDWQTLTRPWQAPLPGNAQRAIGCLECRDTGYHGRAGVYEIMQLSDS
HCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHEEEEEECCCCCCCCHHHHHHHHHHHH
LKALISPDTDLTAIRRQAFKEGMRSLRLSGAQKVAAGLTTLEEVLRVTPQSEQK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]