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The map label for this gene is ahpC [C]

Identifier: 77461637

GI number: 77461637

Start: 6080172

End: 6080810

Strand: Reverse

Name: ahpC [C]

Synonym: Pfl01_5416

Alternate gene names: 77461637

Gene position: 6080810-6080172 (Counterclockwise)

Preceding gene: 77461638

Following gene: 77461636

Centisome position: 94.45

GC content: 58.22

Gene sequence:

>639_bases
ATGAGCCTCAGACTTGGCGATATCGCCCCCGATTTCGAACAGGATTCCAGCGCCGGCAAGATTCGTTTCCACGAATGGCT
GGGCGATAGCTGGGGCGTGCTGTTTTCCCACCCGGCGGACTTCACCCCGGTCTGCACCACCGAGCTGGGCTTCACTGCCA
AGCTCAAGGACGAATTCACCAAACGTGGCGTGAAAGCCATTGCACTGTCGGTCGACCCGGTGGACTCGCACCACAAGTGG
ATCGAGGACATCAACGAAACCCAGAACACCATCGTCAATTTCCCGATCCTGGCCGATGCCGATCGCAAGGTGTCCGATCT
GTACGATCTGATCCACCCGAACGCCAACGACACCCTGACCGTGCGTTCGCTGTTCGTGATCGATCCGAACAAGAAGATCC
GCCTGACCATCACTTACCCGGCGAGCACCGGCCGCAACTTCCACGAGATTCTGCGGGTGATCGATTCGCTGCAGCTCACC
GACAACTACAAGGTGGCCACCCCGGCCAACTGGCAGGACGGTGAAGAGGTGGTAATCGTGCCGTCACTCAAGGACGAAGA
CGAAATCAAACAACGCTTTCCGAAGGGCTACCGCGCGGTGAAGCCGTACCTGCGCCTTACACCACAGCCGAACAAATAA

Upstream 100 bases:

>100_bases
TATTCAATAAAGATATAAATATCTAGTTATTTATTCTTTTTAAGAAGAACGAATCACGAGCTACAGTTGAGGTCTCCAAC
CACTCATCAGGAGCCGCACC

Downstream 100 bases:

>100_bases
ACTACCTCGGATCGTTCCCAGGCTCTGCATGGGGCGATCAGCAAAAACCACGATGCAGGGTTTCAGGCCGTCTTTACGGC
CTGTTTTTTTGCCCGCAGGA

Product: 1-Cys peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLRLGDIAPDFEQDSSAGKIRFHEWLGDSWGVLFSHPADFTPVCTTELGFTAKLKDEFTKRGVKAIALSVDPVDSHHKW
IEDINETQNTIVNFPILADADRKVSDLYDLIHPNANDTLTVRSLFVIDPNKKIRLTITYPASTGRNFHEILRVIDSLQLT
DNYKVATPANWQDGEEVVIVPSLKDEDEIKQRFPKGYRAVKPYLRLTPQPNK

Sequences:

>Translated_212_residues
MSLRLGDIAPDFEQDSSAGKIRFHEWLGDSWGVLFSHPADFTPVCTTELGFTAKLKDEFTKRGVKAIALSVDPVDSHHKW
IEDINETQNTIVNFPILADADRKVSDLYDLIHPNANDTLTVRSLFVIDPNKKIRLTITYPASTGRNFHEILRVIDSLQLT
DNYKVATPANWQDGEEVVIVPSLKDEDEIKQRFPKGYRAVKPYLRLTPQPNK
>Mature_211_residues
SLRLGDIAPDFEQDSSAGKIRFHEWLGDSWGVLFSHPADFTPVCTTELGFTAKLKDEFTKRGVKAIALSVDPVDSHHKWI
EDINETQNTIVNFPILADADRKVSDLYDLIHPNANDTLTVRSLFVIDPNKKIRLTITYPASTGRNFHEILRVIDSLQLTD
NYKVATPANWQDGEEVVIVPSLKDEDEIKQRFPKGYRAVKPYLRLTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=51.8018018018018, Blast_Score=225, Evalue=2e-59,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=31.0526315789474, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=28.021978021978, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=28.021978021978, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=28.021978021978, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5453549, Length=149, Percent_Identity=31.5436241610738, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI5802974, Length=140, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786822, Length=156, Percent_Identity=31.4102564102564, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=41.2060301507538, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17554494, Length=144, Percent_Identity=31.9444444444444, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=29.1005291005291, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=29.1005291005291, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=56.1320754716981, Blast_Score=226, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323613, Length=158, Percent_Identity=30.379746835443, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=49.7716894977169, Blast_Score=215, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=50.4854368932039, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=50, Blast_Score=194, Evalue=3e-50,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=50, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI17738015, Length=202, Percent_Identity=30.1980198019802, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17157991, Length=169, Percent_Identity=30.1775147928994, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641739, Length=169, Percent_Identity=30.1775147928994, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=27.4611398963731, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24073; Mature: 23942

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLGDIAPDFEQDSSAGKIRFHEWLGDSWGVLFSHPADFTPVCTTELGFTAKLKDEFT
CCCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRGVKAIALSVDPVDSHHKWIEDINETQNTIVNFPILADADRKVSDLYDLIHPNANDTLT
HCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEECCEEECCCCHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKIRLTITYPASTGRNFHEILRVIDSLQLTDNYKVATPANWQDGEEVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
PSLKDEDEIKQRFPKGYRAVKPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC
>Mature Secondary Structure 
SLRLGDIAPDFEQDSSAGKIRFHEWLGDSWGVLFSHPADFTPVCTTELGFTAKLKDEFT
CCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCEEEECCCCCCCEEECCCCCEEHHHHHHH
KRGVKAIALSVDPVDSHHKWIEDINETQNTIVNFPILADADRKVSDLYDLIHPNANDTLT
HCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEECCEEECCCCHHHHHHHHHCCCCCCEEE
VRSLFVIDPNKKIRLTITYPASTGRNFHEILRVIDSLQLTDNYKVATPANWQDGEEVVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEE
PSLKDEDEIKQRFPKGYRAVKPYLRLTPQPNK
CCCCCHHHHHHHCCCCHHHHCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]