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The map label for this gene is ycgM [H]

Identifier: 77461606

GI number: 77461606

Start: 6048054

End: 6048719

Strand: Reverse

Name: ycgM [H]

Synonym: Pfl01_5385

Alternate gene names: 77461606

Gene position: 6048719-6048054 (Counterclockwise)

Preceding gene: 77461607

Following gene: 77461605

Centisome position: 93.95

GC content: 62.31

Gene sequence:

>666_bases
ATGAGCTATCAGCACCAGTATGTCGACGGTACGCGGATTCATTTTCCGCTGGGGAAAGTGGTGTGCATCGGCCGTAACTA
CGCCGAACACGCCAAGGAACTGGACAACCCGGTGCCTACCGAGCCGTTGCTGTTCATCAAGCCGGGCAGTTGCGTGGTGC
CGCTGGAAGGCAGTTTCAGCATTCCGACCGAGCGTGGCTCGGTGCATTACGAGGCGGAAATCGCCGTGTTGATCGGCAAA
CCGCTGTCGACCAAACCGAGCCGTGAAGAAGTGCTGGACGCGATCTCCGGTTTCGCCCCGGCGCTGGACCTGACCCTGCG
CGACAAGCAGGCCGAGCTCAAATCCAAGGGCCTGCCGTGGGAAATCGCCAAGTCGTTCGACGGCGCGGCGGTGATTGCAC
CGTTCGTGGTCGGCAGCACTTTCGCCGACCTGACCGACATCGGCATTCGCCTGACCATCAATGGCGAAGTGCGCCAGGAC
GGTAACAGCAGCGCCATGCTCAACCCGATCGTGCCGATGATCCAGCACATGGCCGGCTGCTTCTCGCTGCAGGCCGGTGA
CGTGATCCTGACCGGCACGCCAGTGGGCGTCGGCCCGCTGAACGTTGGCGATGAGATCGTGCTGGAACTGCCGGGCGCCA
GTCGTTTTACCAGCAGCGTTCGCTGA

Upstream 100 bases:

>100_bases
GTCAAGGCGGTGTTCGACCCGAACGGCATCATGAACCCGGGCAAGATTTTCGCGGTTTGATTGGCAATCCCTGATGAATC
AATAAAGGCAGGAGTCGGTA

Downstream 100 bases:

>100_bases
TCCGTACATCGCGTTGCCGAGCGGGAGATGGCAGGTTTGAGCTCAGCCCTCAGTCTGCAATCTCCCGTTTTCGTTTTGTG
ATGCGGCCTGCAAAGACGCA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSYQHQYVDGTRIHFPLGKVVCIGRNYAEHAKELDNPVPTEPLLFIKPGSCVVPLEGSFSIPTERGSVHYEAEIAVLIGK
PLSTKPSREEVLDAISGFAPALDLTLRDKQAELKSKGLPWEIAKSFDGAAVIAPFVVGSTFADLTDIGIRLTINGEVRQD
GNSSAMLNPIVPMIQHMAGCFSLQAGDVILTGTPVGVGPLNVGDEIVLELPGASRFTSSVR

Sequences:

>Translated_221_residues
MSYQHQYVDGTRIHFPLGKVVCIGRNYAEHAKELDNPVPTEPLLFIKPGSCVVPLEGSFSIPTERGSVHYEAEIAVLIGK
PLSTKPSREEVLDAISGFAPALDLTLRDKQAELKSKGLPWEIAKSFDGAAVIAPFVVGSTFADLTDIGIRLTINGEVRQD
GNSSAMLNPIVPMIQHMAGCFSLQAGDVILTGTPVGVGPLNVGDEIVLELPGASRFTSSVR
>Mature_220_residues
SYQHQYVDGTRIHFPLGKVVCIGRNYAEHAKELDNPVPTEPLLFIKPGSCVVPLEGSFSIPTERGSVHYEAEIAVLIGKP
LSTKPSREEVLDAISGFAPALDLTLRDKQAELKSKGLPWEIAKSFDGAAVIAPFVVGSTFADLTDIGIRLTINGEVRQDG
NSSAMLNPIVPMIQHMAGCFSLQAGDVILTGTPVGVGPLNVGDEIVLELPGASRFTSSVR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=205, Percent_Identity=39.5121951219512, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=38.8059701492537, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI66348062, Length=187, Percent_Identity=40.1069518716578, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI156231349, Length=200, Percent_Identity=35.5, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI40786394, Length=200, Percent_Identity=34.5, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI1787428, Length=216, Percent_Identity=46.7592592592593, Blast_Score=204, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=38.5416666666667, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=241, Percent_Identity=41.49377593361, Blast_Score=168, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=30.0492610837438, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28572127, Length=211, Percent_Identity=28.9099526066351, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24663695, Length=214, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23607; Mature: 23476

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQHQYVDGTRIHFPLGKVVCIGRNYAEHAKELDNPVPTEPLLFIKPGSCVVPLEGSFS
CCCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCC
IPTERGSVHYEAEIAVLIGKPLSTKPSREEVLDAISGFAPALDLTLRDKQAELKSKGLPW
CCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCH
EIAKSFDGAAVIAPFVVGSTFADLTDIGIRLTINGEVRQDGNSSAMLNPIVPMIQHMAGC
HHHHCCCCCEEEHHHHHCCHHHHHHHCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHH
FSLQAGDVILTGTPVGVGPLNVGDEIVLELPGASRFTSSVR
EEECCCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHCCCC
>Mature Secondary Structure 
SYQHQYVDGTRIHFPLGKVVCIGRNYAEHAKELDNPVPTEPLLFIKPGSCVVPLEGSFS
CCCCCCCCCCEEEECCCEEEEECCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCC
IPTERGSVHYEAEIAVLIGKPLSTKPSREEVLDAISGFAPALDLTLRDKQAELKSKGLPW
CCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCH
EIAKSFDGAAVIAPFVVGSTFADLTDIGIRLTINGEVRQDGNSSAMLNPIVPMIQHMAGC
HHHHCCCCCEEEHHHHHCCHHHHHHHCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHH
FSLQAGDVILTGTPVGVGPLNVGDEIVLELPGASRFTSSVR
EEECCCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]