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The map label for this gene is ydhC [H]

Identifier: 77461578

GI number: 77461578

Start: 6016110

End: 6017327

Strand: Direct

Name: ydhC [H]

Synonym: Pfl01_5357

Alternate gene names: 77461578

Gene position: 6016110-6017327 (Clockwise)

Preceding gene: 77461577

Following gene: 77461579

Centisome position: 93.44

GC content: 61.25

Gene sequence:

>1218_bases
ATGGATGACGGACAATCTGTGGTGACCCGACGACAGCGGCGCGGGGCTGTCAGTCTGTTGCTGGCAATGGTGTTGCTCGG
CGTCTTTCCCTTGGATGTCCTGCTGCCTTCGTTCCCGGCCCTGGCCGAACACTTTCGCCGCACCCCGGCGGACATCGCCC
TGTCGGTCAGCCTGTTTGCGGTCGGGATTGCCTTCGCCCAGTTGCTGATCGGGCCGCTGTCGGATGTGATCGGACGCAAG
GGACTGCTGCTCGCCGGCATGAGCGTTTCCATACTCGGTGCCCTCGGGTGCGTGATGACCTCGGACTATTCGCTGTTTCT
GATTTTTCGGGTGGTGCAGGCGCTGGGGTGCGGTTGCTTCGTGCTGTCACAGGCGCTGGTGCAGGACCTGTTTGAAGGCG
AGCAACGTGATCGCCTGAGGATCCTGATGGTGACCGCCGGCGGGATTTTCATCTCGGTATCGCCGCTGGCTGGCACCTTT
CTTCAGGCGACATTGGGCTGGCGCGGCAGTTTCTGGGTATTCATCGCATTATCAGCCGCAGTGCTGCTCAAGGCCTGGAT
GTTTCTGGAGAACTCCCGACCGAGCGCCAGCGGCACACGTACGAACTTCCTCACGGCCTATCGACGGGTTCTGGGAGATT
TCGACTTCGTCGGTTACTGGCTGATTTCAGCGTTTGCATTCGCCTGCCACTTTTCATTCATCGTGATCTCGCCGCTGATC
TTCATGGATCGGCTGCAACTGACCGCTTACGAATTTTCGTTGATCCTGCTGATCTACGGTGCGGCTTACGTCACCGGGGG
CATCCTCGCCAGCGTGCTGAGCAGGCGTATCAACAGCGGCCAGCAGATGGTCGTCGGCCTGAGCCTGATCCTGTTCGCCG
GCGTGGCCATGCTGTACCTGGCGTCGAACTTTGCACTGGCTCCGGCGACCGTGCTGATCCCGATGCTGATCTGCACCGCC
GGCACCACCATTGCCCGGCCGGCGGCCACGTCCCGGGCCATGAGTCTGTTTCCGGAAAACGCCGGCACCTCGGCCTCGGC
CGGCAGCACGATCATTTTCATCTGCGGCGGCTTGATCAGTGCCTTGATCAGCCTGAGCCCGACCAATCTGCAATCCACGC
TGGGCTACAGCTTCGTGATACTCAGCGGGGTGGCACTGGCAATGAACGCGCGGATCAGCCGGCGCAACGATCTCGAGGGG
CAACCGGACAGCGATTAA

Upstream 100 bases:

>100_bases
GCACGGGCCGGCAGCCTCGCCACATTGAGCGCATTGAAAAAAGCCGGATTTTTTACCGAACCTCAAAACCAGACACTATT
TGCCAGGGCAGGACTGATCG

Downstream 100 bases:

>100_bases
TCCTGCCGGTCGTCATCCCGCACGCTTCGTCAGCACTGGAACAACGCTTTGCGCCATTCCCTCCTGACGCCAGCGGTGTA
GAATCGCGAGATTCATCGCC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDDGQSVVTRRQRRGAVSLLLAMVLLGVFPLDVLLPSFPALAEHFRRTPADIALSVSLFAVGIAFAQLLIGPLSDVIGRK
GLLLAGMSVSILGALGCVMTSDYSLFLIFRVVQALGCGCFVLSQALVQDLFEGEQRDRLRILMVTAGGIFISVSPLAGTF
LQATLGWRGSFWVFIALSAAVLLKAWMFLENSRPSASGTRTNFLTAYRRVLGDFDFVGYWLISAFAFACHFSFIVISPLI
FMDRLQLTAYEFSLILLIYGAAYVTGGILASVLSRRINSGQQMVVGLSLILFAGVAMLYLASNFALAPATVLIPMLICTA
GTTIARPAATSRAMSLFPENAGTSASAGSTIIFICGGLISALISLSPTNLQSTLGYSFVILSGVALAMNARISRRNDLEG
QPDSD

Sequences:

>Translated_405_residues
MDDGQSVVTRRQRRGAVSLLLAMVLLGVFPLDVLLPSFPALAEHFRRTPADIALSVSLFAVGIAFAQLLIGPLSDVIGRK
GLLLAGMSVSILGALGCVMTSDYSLFLIFRVVQALGCGCFVLSQALVQDLFEGEQRDRLRILMVTAGGIFISVSPLAGTF
LQATLGWRGSFWVFIALSAAVLLKAWMFLENSRPSASGTRTNFLTAYRRVLGDFDFVGYWLISAFAFACHFSFIVISPLI
FMDRLQLTAYEFSLILLIYGAAYVTGGILASVLSRRINSGQQMVVGLSLILFAGVAMLYLASNFALAPATVLIPMLICTA
GTTIARPAATSRAMSLFPENAGTSASAGSTIIFICGGLISALISLSPTNLQSTLGYSFVILSGVALAMNARISRRNDLEG
QPDSD
>Mature_405_residues
MDDGQSVVTRRQRRGAVSLLLAMVLLGVFPLDVLLPSFPALAEHFRRTPADIALSVSLFAVGIAFAQLLIGPLSDVIGRK
GLLLAGMSVSILGALGCVMTSDYSLFLIFRVVQALGCGCFVLSQALVQDLFEGEQRDRLRILMVTAGGIFISVSPLAGTF
LQATLGWRGSFWVFIALSAAVLLKAWMFLENSRPSASGTRTNFLTAYRRVLGDFDFVGYWLISAFAFACHFSFIVISPLI
FMDRLQLTAYEFSLILLIYGAAYVTGGILASVLSRRINSGQQMVVGLSLILFAGVAMLYLASNFALAPATVLIPMLICTA
GTTIARPAATSRAMSLFPENAGTSASAGSTIIFICGGLISALISLSPTNLQSTLGYSFVILSGVALAMNARISRRNDLEG
QPDSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=386, Percent_Identity=28.4974093264249, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790146, Length=336, Percent_Identity=24.1071428571429, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788509, Length=372, Percent_Identity=23.3870967741935, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082312, Length=373, Percent_Identity=25.7372654155496, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787065, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43230; Mature: 43230

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDGQSVVTRRQRRGAVSLLLAMVLLGVFPLDVLLPSFPALAEHFRRTPADIALSVSLFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
VGIAFAQLLIGPLSDVIGRKGLLLAGMSVSILGALGCVMTSDYSLFLIFRVVQALGCGCF
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
VLSQALVQDLFEGEQRDRLRILMVTAGGIFISVSPLAGTFLQATLGWRGSFWVFIALSAA
HHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHH
VLLKAWMFLENSRPSASGTRTNFLTAYRRVLGDFDFVGYWLISAFAFACHFSFIVISPLI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FMDRLQLTAYEFSLILLIYGAAYVTGGILASVLSRRINSGQQMVVGLSLILFAGVAMLYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ASNFALAPATVLIPMLICTAGTTIARPAATSRAMSLFPENAGTSASAGSTIIFICGGLIS
HHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
ALISLSPTNLQSTLGYSFVILSGVALAMNARISRRNDLEGQPDSD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDDGQSVVTRRQRRGAVSLLLAMVLLGVFPLDVLLPSFPALAEHFRRTPADIALSVSLFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
VGIAFAQLLIGPLSDVIGRKGLLLAGMSVSILGALGCVMTSDYSLFLIFRVVQALGCGCF
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
VLSQALVQDLFEGEQRDRLRILMVTAGGIFISVSPLAGTFLQATLGWRGSFWVFIALSAA
HHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHH
VLLKAWMFLENSRPSASGTRTNFLTAYRRVLGDFDFVGYWLISAFAFACHFSFIVISPLI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FMDRLQLTAYEFSLILLIYGAAYVTGGILASVLSRRINSGQQMVVGLSLILFAGVAMLYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ASNFALAPATVLIPMLICTAGTTIARPAATSRAMSLFPENAGTSASAGSTIIFICGGLIS
HHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHH
ALISLSPTNLQSTLGYSFVILSGVALAMNARISRRNDLEGQPDSD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]