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The map label for this gene is betA [C]

Identifier: 77461568

GI number: 77461568

Start: 6006929

End: 6008524

Strand: Direct

Name: betA [C]

Synonym: Pfl01_5347

Alternate gene names: 77461568

Gene position: 6006929-6008524 (Clockwise)

Preceding gene: 77461567

Following gene: 77461569

Centisome position: 93.3

GC content: 64.04

Gene sequence:

>1596_bases
ATGCCCGTACCCGACCCGTTTCGCGAAGGCCTTGCCCGTGGCTGGAAAACCTACAACGGCGCGCAACTCACCGATGACCT
GACCCTGGAAGCCGATGTCGCCATCATCGGCAGCGGCGCCGGCGGCGGCACCACCGCGGAAATCCTCAGCGCCGCCGGCT
ACAAGGTGCTGCTGATCGAAGAAGGTCCGCTCAAGACCAGCAGCGATTTCAAACTGCTGGAGGACCAGGCCTACAGCAGC
CTCTATCAGGAAGGCATCGGCCGCATGAGCAAGGACGGCGCGATCACCATCCTTCAGGGCCGCGCGGTCGGCGGCACCAC
GCTGATCAACTGGACATCGAGTTTTCGCACGCCCGAGCCGACCCTCGAACACTGGGCCAAAGAGCACAACGTCAAAGGCC
ACAGCCCCGCCGACATGGCGCCGTGGTTCGAAAAAATGGAGCAGCGCCTCGGCGTCGCCCCGTGGATGGTGCCGCCCAAC
GCCAACAACGACGTGATCCGCAAAGGCTGCGAACAACTCGGCTACAGCTGGCACGTGATCCCGCGCAACGTGCGCGGCTG
CTGGAACCTCGGCTATTGCGGCATGGGCTGCCCGACCAATGCCAAGCAATCGATGATGGTCACGACCATTCCGGCAACCC
TGGAAAAGGGTGGCGAGCTGCTTTATCTGGCCCGGGCCGAAAAGCTGTTGATCAACGGCGACAAGGTCACCGGCCTGCAA
TGCGTGGCGATGGACGAACGTTGCGTCGAGCCGACTGGACGCACGATCACCGTCAAGGCACGGCATTACGTGCTGGCCGG
CGGTGGGATCAACAGCCCGGCGCTGCTGATGCGTTCGGACGCACCGGATCCGCACAAACGCCTGGGCAAGCGCACCTTCC
TGCATCTGGTGAACATGTCCGCCGGGCGTTTCGACGAGGTCATCAACCCGTTCTACGGTGCGCCGCAGTCGATTTACTCG
GACCATTTCCAGTGGAAGGACGGCACCACCGGCCCGATGGCCTACAAACTCGAAGTGCCGCCGCTGCACCCGGCGCTGGC
CGCCACGTTGCTCGGTGGTTTTGGTCAGGAAAGCGCGCAACACATGGCGGACCTGCCGCACACCCACGCGATGCTGGCCC
TGCTGCGCGACGGTTTTCACCCGGACAGTCAGGGCGGCAGTGTCGAGCTGCGCGGTGACGGCTCGCCGGTGCTCGACTAT
CAGGTGTCGCCTTACACCTGGGAGGGTCTGCGCCGCTCATTCCACAGCATGGCCGAGATCCAGTTCGCCGGCGGCGCCAA
AGCGGTGATGCCGATGCACGCCGATGCACGTTACGTGAACAGCCTGGCCGAGGCCCGCTCATTGATCGACAGCCTGAGTC
TGGAGTTGTATCGCACGCGTCTGGGCAGCGCCCACGTCATGGGCGGTTGCGCCATGGGCGAGGACCCGAAAACCGCCGTC
ACCGACAGCCTCGGCCGCCATCATCAACTGCGCAATCTGTCGATTCATGACGGCTCGCTGTTCCCCACCAGCATCGGCGC
CAACCCGCAGTTGTCGGTGTATGGTCTGACGGCGCAACTGGCGACATCCCTCGGCGAACGGTTGAGAAAACCGTGA

Upstream 100 bases:

>100_bases
GTACACCCGCGCCGAATCCTGGGCCCATTGCGGTTACCCCGGCCCGCCCGCCGTTTGAGCCTGGCGACCCACGCAAAACA
ATAATAAGAGAACCTGATCG

Downstream 100 bases:

>100_bases
AAAAGACGAAATTTCCGATCGTCTATAGTGCTTTCTTACCCAACAGGCGACTTTCCCCACCGGGACGGCTGCGATACCAT
CCGACTCCCCAACGGATTCC

Product: glucose-methanol-choline oxidoreductase

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MPVPDPFREGLARGWKTYNGAQLTDDLTLEADVAIIGSGAGGGTTAEILSAAGYKVLLIEEGPLKTSSDFKLLEDQAYSS
LYQEGIGRMSKDGAITILQGRAVGGTTLINWTSSFRTPEPTLEHWAKEHNVKGHSPADMAPWFEKMEQRLGVAPWMVPPN
ANNDVIRKGCEQLGYSWHVIPRNVRGCWNLGYCGMGCPTNAKQSMMVTTIPATLEKGGELLYLARAEKLLINGDKVTGLQ
CVAMDERCVEPTGRTITVKARHYVLAGGGINSPALLMRSDAPDPHKRLGKRTFLHLVNMSAGRFDEVINPFYGAPQSIYS
DHFQWKDGTTGPMAYKLEVPPLHPALAATLLGGFGQESAQHMADLPHTHAMLALLRDGFHPDSQGGSVELRGDGSPVLDY
QVSPYTWEGLRRSFHSMAEIQFAGGAKAVMPMHADARYVNSLAEARSLIDSLSLELYRTRLGSAHVMGGCAMGEDPKTAV
TDSLGRHHQLRNLSIHDGSLFPTSIGANPQLSVYGLTAQLATSLGERLRKP

Sequences:

>Translated_531_residues
MPVPDPFREGLARGWKTYNGAQLTDDLTLEADVAIIGSGAGGGTTAEILSAAGYKVLLIEEGPLKTSSDFKLLEDQAYSS
LYQEGIGRMSKDGAITILQGRAVGGTTLINWTSSFRTPEPTLEHWAKEHNVKGHSPADMAPWFEKMEQRLGVAPWMVPPN
ANNDVIRKGCEQLGYSWHVIPRNVRGCWNLGYCGMGCPTNAKQSMMVTTIPATLEKGGELLYLARAEKLLINGDKVTGLQ
CVAMDERCVEPTGRTITVKARHYVLAGGGINSPALLMRSDAPDPHKRLGKRTFLHLVNMSAGRFDEVINPFYGAPQSIYS
DHFQWKDGTTGPMAYKLEVPPLHPALAATLLGGFGQESAQHMADLPHTHAMLALLRDGFHPDSQGGSVELRGDGSPVLDY
QVSPYTWEGLRRSFHSMAEIQFAGGAKAVMPMHADARYVNSLAEARSLIDSLSLELYRTRLGSAHVMGGCAMGEDPKTAV
TDSLGRHHQLRNLSIHDGSLFPTSIGANPQLSVYGLTAQLATSLGERLRKP
>Mature_530_residues
PVPDPFREGLARGWKTYNGAQLTDDLTLEADVAIIGSGAGGGTTAEILSAAGYKVLLIEEGPLKTSSDFKLLEDQAYSSL
YQEGIGRMSKDGAITILQGRAVGGTTLINWTSSFRTPEPTLEHWAKEHNVKGHSPADMAPWFEKMEQRLGVAPWMVPPNA
NNDVIRKGCEQLGYSWHVIPRNVRGCWNLGYCGMGCPTNAKQSMMVTTIPATLEKGGELLYLARAEKLLINGDKVTGLQC
VAMDERCVEPTGRTITVKARHYVLAGGGINSPALLMRSDAPDPHKRLGKRTFLHLVNMSAGRFDEVINPFYGAPQSIYSD
HFQWKDGTTGPMAYKLEVPPLHPALAATLLGGFGQESAQHMADLPHTHAMLALLRDGFHPDSQGGSVELRGDGSPVLDYQ
VSPYTWEGLRRSFHSMAEIQFAGGAKAVMPMHADARYVNSLAEARSLIDSLSLELYRTRLGSAHVMGGCAMGEDPKTAVT
DSLGRHHQLRNLSIHDGSLFPTSIGANPQLSVYGLTAQLATSLGERLRKP

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 57612; Mature: 57481

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPDPFREGLARGWKTYNGAQLTDDLTLEADVAIIGSGAGGGTTAEILSAAGYKVLLIE
CCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
EGPLKTSSDFKLLEDQAYSSLYQEGIGRMSKDGAITILQGRAVGGTTLINWTSSFRTPEP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCH
TLEHWAKEHNVKGHSPADMAPWFEKMEQRLGVAPWMVPPNANNDVIRKGCEQLGYSWHVI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCEEEEE
PRNVRGCWNLGYCGMGCPTNAKQSMMVTTIPATLEKGGELLYLARAEKLLINGDKVTGLQ
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCEEEEEECCEEEECCCCCCCEE
CVAMDERCVEPTGRTITVKARHYVLAGGGINSPALLMRSDAPDPHKRLGKRTFLHLVNMS
EEEECCHHCCCCCCEEEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
AGRFDEVINPFYGAPQSIYSDHFQWKDGTTGPMAYKLEVPPLHPALAATLLGGFGQESAQ
CCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHH
HMADLPHTHAMLALLRDGFHPDSQGGSVELRGDGSPVLDYQVSPYTWEGLRRSFHSMAEI
HHHHCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHEE
QFAGGAKAVMPMHADARYVNSLAEARSLIDSLSLELYRTRLGSAHVMGGCAMGEDPKTAV
EECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHH
TDSLGRHHQLRNLSIHDGSLFPTSIGANPQLSVYGLTAQLATSLGERLRKP
HHHHHHHHHHCEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVPDPFREGLARGWKTYNGAQLTDDLTLEADVAIIGSGAGGGTTAEILSAAGYKVLLIE
CCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
EGPLKTSSDFKLLEDQAYSSLYQEGIGRMSKDGAITILQGRAVGGTTLINWTSSFRTPEP
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCH
TLEHWAKEHNVKGHSPADMAPWFEKMEQRLGVAPWMVPPNANNDVIRKGCEQLGYSWHVI
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHCCEEEEE
PRNVRGCWNLGYCGMGCPTNAKQSMMVTTIPATLEKGGELLYLARAEKLLINGDKVTGLQ
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCEEEEEECCEEEECCCCCCCEE
CVAMDERCVEPTGRTITVKARHYVLAGGGINSPALLMRSDAPDPHKRLGKRTFLHLVNMS
EEEECCHHCCCCCCEEEEEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
AGRFDEVINPFYGAPQSIYSDHFQWKDGTTGPMAYKLEVPPLHPALAATLLGGFGQESAQ
CCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHH
HMADLPHTHAMLALLRDGFHPDSQGGSVELRGDGSPVLDYQVSPYTWEGLRRSFHSMAEI
HHHHCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHEE
QFAGGAKAVMPMHADARYVNSLAEARSLIDSLSLELYRTRLGSAHVMGGCAMGEDPKTAV
EECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHH
TDSLGRHHQLRNLSIHDGSLFPTSIGANPQLSVYGLTAQLATSLGERLRKP
HHHHHHHHHHCEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]