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The map label for this gene is pilH [H]

Identifier: 77461528

GI number: 77461528

Start: 5973552

End: 5973917

Strand: Reverse

Name: pilH [H]

Synonym: Pfl01_5307

Alternate gene names: 77461528

Gene position: 5973917-5973552 (Counterclockwise)

Preceding gene: 77461529

Following gene: 77461527

Centisome position: 92.79

GC content: 60.11

Gene sequence:

>366_bases
ATGGCACGTATCCTGATCGTCGACGATTCGCCGACCGAAATGTACAAACTCACCGGCATGCTGGAAAAGCACGGGCACGA
AGTGCTGAAAGCCGAAAACGGCGCCGACGGCGTGGCCCTGGCCCGTCAGGAAAAACCCGATGCGGTGCTGATGGACATCG
TCATGCCCGGCCTCAACGGCTTCCAGGCTACCCGTCAGTTGACCAAGGATGCGGAAACCAGCCACATCCCGGTGATCATC
ATCACCACCAAGGATCAGGAGACCGACAAGGTCTGGGGCACCCGCCAGGGCGCCAGGGACTACCTGACCAAACCGGTCGA
CGAAGACACGCTGATCAAGACCCTGAACAACGTGCTGGCCGGTTGA

Upstream 100 bases:

>100_bases
GGCCCATGTTCCGGGCTTCGCTGCCGCTTTGCCGCAGTAAGACACGCACAGAGACGCTCGGCCAGCGGGCCCGGTGTCGA
CAAGAAAAATGGGGAAGACC

Downstream 100 bases:

>100_bases
TCGCGCCGCCATGAGCGAGTCGCTGACCGCGTTCGAACTGTTGTGGCAGATCGACCAGCGCTGTCGCCTACTGGCGGCGG
ACCTGCCGTCGCAACCGGCG

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNGFQATRQLTKDAETSHIPVII
ITTKDQETDKVWGTRQGARDYLTKPVDEDTLIKTLNNVLAG

Sequences:

>Translated_121_residues
MARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNGFQATRQLTKDAETSHIPVII
ITTKDQETDKVWGTRQGARDYLTKPVDEDTLIKTLNNVLAG
>Mature_120_residues
ARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNGFQATRQLTKDAETSHIPVIII
TTKDQETDKVWGTRQGARDYLTKPVDEDTLIKTLNNVLAG

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=32.4786324786325, Blast_Score=76, Evalue=8e-16,
Organism=Escherichia coli, GI1788905, Length=118, Percent_Identity=36.4406779661017, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790863, Length=117, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=9e-14,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=29.9145299145299, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=36.697247706422, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=33.9622641509434, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1790860, Length=103, Percent_Identity=31.0679611650485, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=28.9256198347107, Blast_Score=60, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13328; Mature: 13197

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNG
CEEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCCCEEEECCCCCCCEEEEHHHCCCCH
FQATRQLTKDAETSHIPVIIITTKDQETDKVWGTRQGARDYLTKPVDEDTLIKTLNNVLA
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHC
G
C
>Mature Secondary Structure 
ARILIVDDSPTEMYKLTGMLEKHGHEVLKAENGADGVALARQEKPDAVLMDIVMPGLNG
EEEEEEECCCHHHHHHHHHHHHCCHHHHHCCCCCCCEEEECCCCCCCEEEEHHHCCCCH
FQATRQLTKDAETSHIPVIIITTKDQETDKVWGTRQGARDYLTKPVDEDTLIKTLNNVLA
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]