Click here to switch to the map view.

The map label for this gene is mdcB

Identifier: 77461522

GI number: 77461522

Start: 5961658

End: 5962530

Strand: Reverse

Name: mdcB

Synonym: Pfl01_5301

Alternate gene names: 77461522

Gene position: 5962530-5961658 (Counterclockwise)

Preceding gene: 77461523

Following gene: 77461521

Centisome position: 92.61

GC content: 67.58

Gene sequence:

>873_bases
ATGCACGCACTCAACCTGCAACCGAAAACCATCACCCTCGCGGAACGGCTGGCGGATCTGGCCGTGGACGCGCTGATCGA
CGAAGCCGACCTGTCGCCGAAACCGGCGCTGGTCGACCGTCGCGGCAACGGTGCCCACACTGATCTGCACCTGGGATTGA
TGCACGCCTCGGCACTGGCGCTGTGGCCGGCGTTCAAGGAAATGGCCGAAGCCGCGCTTGAGTTCGGCGAGATCGGCTTG
CCGCTGCGCGAAGCCATCGGCCGCATCGGCCGGGAAGGCGAGCAAGCGATGCTCGCCACCACCCACGGCGTCAACACCCA
TCGCGGGGCGATCTGGGCGCTGGGCCTGCTGGTCACGGCTGCTGCGCTGGATACCAAGTCCACCAGCGCTGGCGCCGTTA
CTCTGCGCGCCGCACGTCTGGCATTGCTCGATGACCGTTATGCGCCGCGTCCGCTGAGCCACGGCGCCCAAGTCGCCCAA
CGCTACGGCGCTCGCGGTGCCCGGGAAGAAGCGCAACTTGGTTTCCCGTCGGTGGTGCAACGTGGCTTGCCGCAACTCAA
GCGCAGCCGCGCTGCCGGCCATGGCGAACAGAACGCCCGGCTCGATGCGTTGCTCGCAATCATGACCGACCTCGCCGACA
CCTGCGTCCTGTACCGCGCCGGCGAACAAGGTCTGCACGCCATGCAGCACGGCGCCCGGGCGGTGCTCGACGCCGGCGGC
AGCGCCAGCCTCACCGGTCGCCGTCGCCTGCACGAACTCGATCAACAACTCATTGCATTGAATGCCTCGCCCGGTGGCGC
CGCCGACTTGCTCGCCGCCAGCCTGCTGCTCGATCGAATCGAGCGCGACGGCATCCTTCAGGGAGCGTTTTGA

Upstream 100 bases:

>100_bases
CCGACGCCACCCGCGAACTGCTCGCGGCGAAGAGCGTGGCCGATCTGGTCGAGTGGTCCGGCGGCCTCTACAACCCGCCC
GCCAAGTTCAGGAGCTGGTA

Downstream 100 bases:

>100_bases
TGGAAACCTTATCCTTTGAATTCCCCGCCGGGCAGCCGCCGCGTGGTCGGGCGCTGGTCGGTTGTGTCGGTTCGGGCGAT
CTGGAAGTGCTGATCGAACC

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MHALNLQPKTITLAERLADLAVDALIDEADLSPKPALVDRRGNGAHTDLHLGLMHASALALWPAFKEMAEAALEFGEIGL
PLREAIGRIGREGEQAMLATTHGVNTHRGAIWALGLLVTAAALDTKSTSAGAVTLRAARLALLDDRYAPRPLSHGAQVAQ
RYGARGAREEAQLGFPSVVQRGLPQLKRSRAAGHGEQNARLDALLAIMTDLADTCVLYRAGEQGLHAMQHGARAVLDAGG
SASLTGRRRLHELDQQLIALNASPGGAADLLAASLLLDRIERDGILQGAF

Sequences:

>Translated_290_residues
MHALNLQPKTITLAERLADLAVDALIDEADLSPKPALVDRRGNGAHTDLHLGLMHASALALWPAFKEMAEAALEFGEIGL
PLREAIGRIGREGEQAMLATTHGVNTHRGAIWALGLLVTAAALDTKSTSAGAVTLRAARLALLDDRYAPRPLSHGAQVAQ
RYGARGAREEAQLGFPSVVQRGLPQLKRSRAAGHGEQNARLDALLAIMTDLADTCVLYRAGEQGLHAMQHGARAVLDAGG
SASLTGRRRLHELDQQLIALNASPGGAADLLAASLLLDRIERDGILQGAF
>Mature_290_residues
MHALNLQPKTITLAERLADLAVDALIDEADLSPKPALVDRRGNGAHTDLHLGLMHASALALWPAFKEMAEAALEFGEIGL
PLREAIGRIGREGEQAMLATTHGVNTHRGAIWALGLLVTAAALDTKSTSAGAVTLRAARLALLDDRYAPRPLSHGAQVAQ
RYGARGAREEAQLGFPSVVQRGLPQLKRSRAAGHGEQNARLDALLAIMTDLADTCVLYRAGEQGLHAMQHGARAVLDAGG
SASLTGRRRLHELDQQLIALNASPGGAADLLAASLLLDRIERDGILQGAF

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family

Homologues:

Organism=Escherichia coli, GI1786830, Length=286, Percent_Identity=36.3636363636364, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDCB_PSEPF (Q3K5B6)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_351029.1
- STRING:   Q3K5B6
- GeneID:   3715197
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_5301
- eggNOG:   COG1767
- HOGENOM:   HBG305005
- OMA:   LMHASAL
- ProtClustDB:   PRK01237
- BioCyc:   PFLU205922:PFL_5301-MONOMER
- HAMAP:   MF_01883
- InterPro:   IPR002736
- InterPro:   IPR017555
- TIGRFAMs:   TIGR03132

Pfam domain/function: PF01874 CitG

EC number: =2.7.8.25

Molecular weight: Translated: 30649; Mature: 30649

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALNLQPKTITLAERLADLAVDALIDEADLSPKPALVDRRGNGAHTDLHLGLMHASALA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LWPAFKEMAEAALEFGEIGLPLREAIGRIGREGEQAMLATTHGVNTHRGAIWALGLLVTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AALDTKSTSAGAVTLRAARLALLDDRYAPRPLSHGAQVAQRYGARGAREEAQLGFPSVVQ
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHH
RGLPQLKRSRAAGHGEQNARLDALLAIMTDLADTCVLYRAGEQGLHAMQHGARAVLDAGG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
SASLTGRRRLHELDQQLIALNASPGGAADLLAASLLLDRIERDGILQGAF
CCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHALNLQPKTITLAERLADLAVDALIDEADLSPKPALVDRRGNGAHTDLHLGLMHASALA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHH
LWPAFKEMAEAALEFGEIGLPLREAIGRIGREGEQAMLATTHGVNTHRGAIWALGLLVTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
AALDTKSTSAGAVTLRAARLALLDDRYAPRPLSHGAQVAQRYGARGAREEAQLGFPSVVQ
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHH
RGLPQLKRSRAAGHGEQNARLDALLAIMTDLADTCVLYRAGEQGLHAMQHGARAVLDAGG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
SASLTGRRRLHELDQQLIALNASPGGAADLLAASLLLDRIERDGILQGAF
CCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA