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The map label for this gene is pmbA [C]

Identifier: 77461467

GI number: 77461467

Start: 5905308

End: 5906645

Strand: Direct

Name: pmbA [C]

Synonym: Pfl01_5246

Alternate gene names: 77461467

Gene position: 5905308-5906645 (Clockwise)

Preceding gene: 77461466

Following gene: 77461468

Centisome position: 91.72

GC content: 63.0

Gene sequence:

>1338_bases
ATGAGTATTTCCAAGAACCCGTCCGAGGCGTTCAAGGTGCTGGTCAACTGGCTGCGCGATGCCGTGCGCGAGCCGGAACA
GTTCACCCTGAGTTACGACGCCGAATCGTCGGCCTTCGTCCGTTTCAACCACGCCAAGGTGCGTCAGGCCGGGCAAGTTC
AGCAAGCCGGTATCGGTCTGAAACTGATCGACGACGGTCGCCATGCCGACCTGCACATCACCCTGTCCGGCGAGCAGGCC
ACCGACCTGCAACGTCTTGCCGAAGGCTTGCAACAACTGCGCGAAACCCTGCCGCTGCTGCCGCAGGATCCGTACCTGTT
GCTCAACCACAACGGCTGGCAGAGCAAGAACGTGCAGGAACATCCGCTGCCGGACACCGAGCAGGTGGTGGCGGAAATCG
CTAATGCTGCCGAAGGCCTGGATCTGGTCGGCTTCTATGCCGCCGGGCCGATCAGCCGTGGTTTTGCCAGCTCTTCCGGC
GCGTTCGGCTGGCATCAGGCCAACAGCTTCAACTTCGATTTCAGCCTGTTCCACGAGAACGGCGAAGCGGTGAAAGCCAG
CTACGCCGGGCATGACTGGAACAGCGAAGACTTCGCCAGACGCATCCAGCAGGCCCGCGAGCAACTCGAATTTCTGGGGC
GGCCGCTGCGCACCCTGCCGCCCGGCCAATACCGCGCCTACCTGGCGCCGGCAGCCCTGGAAGAAATCATGGGCATGCTG
TGCTGGGGTGGTTTCTCGGCGCAGTCGATTGCCAGCAAGAGCAGCCCGTTGCAGAAGCTGTATGCCGGCGATCAGGCGTT
CAGCCCGCTGGTGTCCCTCGACGAGAAAGTCAGCGAATCGCTGAGCCCGGCGTTCTCCGGCGAAGGTTACCCGCGCAGCG
ATCTGCGGCTGATCATCGAAGGCAAAGCAGGTGACCAGTTGGTGGGTTCGCGCAGTGCCGCCGAGTACGGTCTGACGGCC
AACGGTGCCAGCGGCGGCGAATCGCCGAGCGCGCTGAACATGGGCGCTGGTGATTTGCCTCAAGCGGAGATTCTCAAGCA
ACTGGGCACCGGGCTGTACATCAGTAACCTGTGGTACCTGAATTTCTCGGATCAACCGGCGGCGCGCCTGACCGGGATGA
CCCGGTTTGCTACCTTCTGGGTCGAGAACGGCGAGATTCAGGCGCCGGTCAGCACCATGCGTTTCGACGACAGCGCCTAC
AGCCTGCTGGGTTCGCAGCTGGAAGCGTTGACCGCCGAGCGCGAGTTGCTGCTGTCGGCGAGCACCTACAGCCAGCGCAA
TACCTCGTCGGCGCTGTTGCCGGGGGCGCTGGTGAGCCGATTGACCCTGACCCTGTAA

Upstream 100 bases:

>100_bases
CGAACTGCGGCAAGGGCGAACCGAACCAGGTGATCCGCGTCGGCCATGCGTCGCCGGCCTGCGTGTTCAGCAATGTTGAT
GTGTTTGGGGGAGACGCCTG

Downstream 100 bases:

>100_bases
ATCCCGGACCTGATCGTTCCCACGCTCTGCGTGGGAATGCATCCCGTGACGCTCCGCGTCACTTTACAGCGGACGCAGAG
CGTCCATGGCGGCATTCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Zn-Dependent Protease; TldD Protein; TldD/PmbA Family Protein; DNA Gyrase Modulator Family Protein; Modulator Of DNA Gyrase; Zn-Dependent Protease-Like Protein

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSISKNPSEAFKVLVNWLRDAVREPEQFTLSYDAESSAFVRFNHAKVRQAGQVQQAGIGLKLIDDGRHADLHITLSGEQA
TDLQRLAEGLQQLRETLPLLPQDPYLLLNHNGWQSKNVQEHPLPDTEQVVAEIANAAEGLDLVGFYAAGPISRGFASSSG
AFGWHQANSFNFDFSLFHENGEAVKASYAGHDWNSEDFARRIQQAREQLEFLGRPLRTLPPGQYRAYLAPAALEEIMGML
CWGGFSAQSIASKSSPLQKLYAGDQAFSPLVSLDEKVSESLSPAFSGEGYPRSDLRLIIEGKAGDQLVGSRSAAEYGLTA
NGASGGESPSALNMGAGDLPQAEILKQLGTGLYISNLWYLNFSDQPAARLTGMTRFATFWVENGEIQAPVSTMRFDDSAY
SLLGSQLEALTAERELLLSASTYSQRNTSSALLPGALVSRLTLTL

Sequences:

>Translated_445_residues
MSISKNPSEAFKVLVNWLRDAVREPEQFTLSYDAESSAFVRFNHAKVRQAGQVQQAGIGLKLIDDGRHADLHITLSGEQA
TDLQRLAEGLQQLRETLPLLPQDPYLLLNHNGWQSKNVQEHPLPDTEQVVAEIANAAEGLDLVGFYAAGPISRGFASSSG
AFGWHQANSFNFDFSLFHENGEAVKASYAGHDWNSEDFARRIQQAREQLEFLGRPLRTLPPGQYRAYLAPAALEEIMGML
CWGGFSAQSIASKSSPLQKLYAGDQAFSPLVSLDEKVSESLSPAFSGEGYPRSDLRLIIEGKAGDQLVGSRSAAEYGLTA
NGASGGESPSALNMGAGDLPQAEILKQLGTGLYISNLWYLNFSDQPAARLTGMTRFATFWVENGEIQAPVSTMRFDDSAY
SLLGSQLEALTAERELLLSASTYSQRNTSSALLPGALVSRLTLTL
>Mature_444_residues
SISKNPSEAFKVLVNWLRDAVREPEQFTLSYDAESSAFVRFNHAKVRQAGQVQQAGIGLKLIDDGRHADLHITLSGEQAT
DLQRLAEGLQQLRETLPLLPQDPYLLLNHNGWQSKNVQEHPLPDTEQVVAEIANAAEGLDLVGFYAAGPISRGFASSSGA
FGWHQANSFNFDFSLFHENGEAVKASYAGHDWNSEDFARRIQQAREQLEFLGRPLRTLPPGQYRAYLAPAALEEIMGMLC
WGGFSAQSIASKSSPLQKLYAGDQAFSPLVSLDEKVSESLSPAFSGEGYPRSDLRLIIEGKAGDQLVGSRSAAEYGLTAN
GASGGESPSALNMGAGDLPQAEILKQLGTGLYISNLWYLNFSDQPAARLTGMTRFATFWVENGEIQAPVSTMRFDDSAYS
LLGSQLEALTAERELLLSASTYSQRNTSSALLPGALVSRLTLTL

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48382; Mature: 48250

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISKNPSEAFKVLVNWLRDAVREPEQFTLSYDAESSAFVRFNHAKVRQAGQVQQAGIGL
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHCCHHHHCCCE
KLIDDGRHADLHITLSGEQATDLQRLAEGLQQLRETLPLLPQDPYLLLNHNGWQSKNVQE
EEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCC
HPLPDTEQVVAEIANAAEGLDLVGFYAAGPISRGFASSSGAFGWHQANSFNFDFSLFHEN
CCCCCHHHHHHHHHHHHCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GEAVKASYAGHDWNSEDFARRIQQAREQLEFLGRPLRTLPPGQYRAYLAPAALEEIMGML
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHH
CWGGFSAQSIASKSSPLQKLYAGDQAFSPLVSLDEKVSESLSPAFSGEGYPRSDLRLIIE
HCCCCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
GKAGDQLVGSRSAAEYGLTANGASGGESPSALNMGAGDLPQAEILKQLGTGLYISNLWYL
CCCCCCHHCCCCHHHCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCEEEEEEEEE
NFSDQPAARLTGMTRFATFWVENGEIQAPVSTMRFDDSAYSLLGSQLEALTAERELLLSA
ECCCCCHHHHHHHHHEEEEEEECCEEECCHHHHEECHHHHHHHHHHHHHHHHHHHHHEEH
STYSQRNTSSALLPGALVSRLTLTL
HHHCCCCCCCHHCHHHHHHHHHHCC
>Mature Secondary Structure 
SISKNPSEAFKVLVNWLRDAVREPEQFTLSYDAESSAFVRFNHAKVRQAGQVQQAGIGL
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHCCHHHHCCCE
KLIDDGRHADLHITLSGEQATDLQRLAEGLQQLRETLPLLPQDPYLLLNHNGWQSKNVQE
EEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCC
HPLPDTEQVVAEIANAAEGLDLVGFYAAGPISRGFASSSGAFGWHQANSFNFDFSLFHEN
CCCCCHHHHHHHHHHHHCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GEAVKASYAGHDWNSEDFARRIQQAREQLEFLGRPLRTLPPGQYRAYLAPAALEEIMGML
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHH
CWGGFSAQSIASKSSPLQKLYAGDQAFSPLVSLDEKVSESLSPAFSGEGYPRSDLRLIIE
HCCCCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
GKAGDQLVGSRSAAEYGLTANGASGGESPSALNMGAGDLPQAEILKQLGTGLYISNLWYL
CCCCCCHHCCCCHHHCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCCCEEEEEEEEE
NFSDQPAARLTGMTRFATFWVENGEIQAPVSTMRFDDSAYSLLGSQLEALTAERELLLSA
ECCCCCHHHHHHHHHEEEEEEECCEEECCHHHHEECHHHHHHHHHHHHHHHHHHHHHEEH
STYSQRNTSSALLPGALVSRLTLTL
HHHCCCCCCCHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA