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The map label for this gene is 77461446

Identifier: 77461446

GI number: 77461446

Start: 5880918

End: 5881895

Strand: Reverse

Name: 77461446

Synonym: Pfl01_5225

Alternate gene names: NA

Gene position: 5881895-5880918 (Counterclockwise)

Preceding gene: 77461449

Following gene: 77461445

Centisome position: 91.36

GC content: 60.22

Gene sequence:

>978_bases
ATGAGCCCAGCCGAATTACACGCCGACAGCATCGTTATCGACGGTCTGATCATTGCCAAATGGAACCGCGAGCTGTTCGA
AGACATGCGCAAGGGCGGTCTGACGGCGGCCAACTGCACCGTGTCGGTGTGGGAGGGCTTTCAGGCCACGGTCAACAACA
TCGCCGCCAGCCAGAAACTGATTCGCGAAAACAGCGACCTGGTGATCCCCGTCCGCACCACCGCCGACATCCGCAAGGCC
AAGGAGCAGGGCAAGACCGGCATCCTCTTCGGCTTCCAGAACGCCCATGCGTTCGAAGACCAGATCGGTTATGTCGAGGT
GTTCAAGCAGCTCGGCGTCGGCATCGTACAGATGTGCTACAACACCCAGAACCTGGTGGGCACCGGTTGCTACGAACGTG
ACGGCGGCCTGTCGGGCTTCGGTCGCGAAATCGTCGCCGAGATGAACCGTGTCGGCGTCATGTGCGACCTGTCCCACGTC
GGCTCCAAGACCTCCGAAGAAGTCATCCTCGAATCGAAAAAACCGGTCTGCTATTCCCACTGCCTGCCGTCGGGGCTGAA
AGAGCACCCGCGCAACAAGTCCGATGAAGAGCTGAAGTTCATCGCTGACCACGGCGGTTTCGTCGGCGTGACCATGTTCG
CGCCGTTCCTGGCCAAGGGCATCGATTCGACCATCGACGACTACGCCGAAGCCATCGAATACACCATGAACATCGTCGGC
GAAGACGCCATCGGCATCGGCACCGACTTCACCCAGGGTCACGGCCAGGACTTCTTCGAATACCTGACCCACGACAAGGG
CTACGCCCGCCGTCTGACCAACTTCGGCAAGATCATCAACCCGCTGGGCATCCGCACCGTCGGCGAGTTCCCGAACCTGA
CCGAAACCCTGCTCAAGCGCGGCCACTCCGAGCGCGTGGTACGCAAGATCATGGGCGAAAACTGGGTGAACGTCCTCAAA
GACGTTTGGGGCGAGTAA

Upstream 100 bases:

>100_bases
TGTCGTTTTTGCACCCGGCTGGTCGCGCACCGAGGCATATGCTGGCCCCAAAGCGCCGGCAGACGATTCGGCGCATGAAT
CGCCAATAAGGGGACGCCTG

Downstream 100 bases:

>100_bases
GCCGCCGCTTCCCGAATACTTTCCCCCGGCCGTCCGTGCCGGGGGCAACACCAAAATTTTCTGGAGTTAAGTTTCCATGG
CCAAGATCGCCCCGCAATTG

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKLIRENSDLVIPVRTTADIRKA
KEQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCYNTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHV
GSKTSEEVILESKKPVCYSHCLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTMNIVG
EDAIGIGTDFTQGHGQDFFEYLTHDKGYARRLTNFGKIINPLGIRTVGEFPNLTETLLKRGHSERVVRKIMGENWVNVLK
DVWGE

Sequences:

>Translated_325_residues
MSPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKLIRENSDLVIPVRTTADIRKA
KEQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCYNTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHV
GSKTSEEVILESKKPVCYSHCLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTMNIVG
EDAIGIGTDFTQGHGQDFFEYLTHDKGYARRLTNFGKIINPLGIRTVGEFPNLTETLLKRGHSERVVRKIMGENWVNVLK
DVWGE
>Mature_324_residues
SPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKLIRENSDLVIPVRTTADIRKAK
EQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCYNTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHVG
SKTSEEVILESKKPVCYSHCLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTMNIVGE
DAIGIGTDFTQGHGQDFFEYLTHDKGYARRLTNFGKIINPLGIRTVGEFPNLTETLLKRGHSERVVRKIMGENWVNVLKD
VWGE

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=291, Percent_Identity=24.3986254295533, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4758190, Length=291, Percent_Identity=24.3986254295533, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI11641269, Length=291, Percent_Identity=23.7113402061856, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI193211608, Length=245, Percent_Identity=24.0816326530612, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI193211610, Length=245, Percent_Identity=24.0816326530612, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281362638, Length=318, Percent_Identity=25.4716981132075, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281362636, Length=318, Percent_Identity=25.4716981132075, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI161083233, Length=315, Percent_Identity=25.7142857142857, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221475880, Length=317, Percent_Identity=24.6056782334385, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 35958; Mature: 35827

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKL
CCCHHHCCCCEEECCEEEECCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHH
IRENSDLVIPVRTTADIRKAKEQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCY
HHCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHVGSKTSEEVILESKKPVCYSH
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHCCCCCHHHHHCCCCCHHHHH
CLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTMNIVG
HCCHHHHHCCCCCCCHHHHEEECCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
EDAIGIGTDFTQGHGQDFFEYLTHDKGYARRLTNFGKIINPLGIRTVGEFPNLTETLLKR
CCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GHSERVVRKIMGENWVNVLKDVWGE
CCHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKL
CCHHHCCCCEEECCEEEECCCHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHH
IRENSDLVIPVRTTADIRKAKEQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCY
HHCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHVGSKTSEEVILESKKPVCYSH
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEHHHHCCCCCHHHHHCCCCCHHHHH
CLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTMNIVG
HCCHHHHHCCCCCCCHHHHEEECCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
EDAIGIGTDFTQGHGQDFFEYLTHDKGYARRLTNFGKIINPLGIRTVGEFPNLTETLLKR
CCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GHSERVVRKIMGENWVNVLKDVWGE
CCHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]